Protein kinase domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

kinetoplastid kinetochore protein 19, putative

Species:

Leishmania braziliensis

UniProt:

A4H5L7_LEIBR

TriTrypDb:

LbrM.09.0420 , LBRM2903_090009700

Length:

476

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 16
NetGPI	no	yes: 0, no: 16

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	2
GO:0005737	cytoplasm	2	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0051286	cell tip	3	2
GO:0060187	cell pole	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

A4H5L7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H5L7

Function

Biological processes
Term	Name	Level	Count
GO:0006468	protein phosphorylation	5	17
GO:0006793	phosphorus metabolic process	3	17
GO:0006796	phosphate-containing compound metabolic process	4	17
GO:0006807	nitrogen compound metabolic process	2	17
GO:0008152	metabolic process	1	17
GO:0009987	cellular process	1	17
GO:0016310	phosphorylation	5	17
GO:0019538	protein metabolic process	3	17
GO:0036211	protein modification process	4	17
GO:0043170	macromolecule metabolic process	3	17
GO:0043412	macromolecule modification	4	17
GO:0044237	cellular metabolic process	2	17
GO:0044238	primary metabolic process	2	17
GO:0071704	organic substance metabolic process	2	17
GO:1901564	organonitrogen compound metabolic process	3	17
GO:0000278	mitotic cell cycle	3	1
GO:0007049	cell cycle	2	1
GO:0008283	cell population proliferation	2	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	17
GO:0003824	catalytic activity	1	17
GO:0004672	protein kinase activity	3	17
GO:0004674	protein serine/threonine kinase activity	4	16
GO:0005488	binding	1	17
GO:0005524	ATP binding	5	17
GO:0016301	kinase activity	4	17
GO:0016740	transferase activity	2	17
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	17
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	17
GO:0017076	purine nucleotide binding	4	17
GO:0030554	adenyl nucleotide binding	5	17
GO:0032553	ribonucleotide binding	3	17
GO:0032555	purine ribonucleotide binding	4	17
GO:0032559	adenyl ribonucleotide binding	5	17
GO:0035639	purine ribonucleoside triphosphate binding	4	17
GO:0036094	small molecule binding	2	17
GO:0043167	ion binding	2	17
GO:0043168	anion binding	3	17
GO:0097159	organic cyclic compound binding	2	17
GO:0097367	carbohydrate derivative binding	2	17
GO:0140096	catalytic activity, acting on a protein	2	17
GO:1901265	nucleoside phosphate binding	3	17
GO:1901363	heterocyclic compound binding	2	17

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	275	279	PF00656	0.233
CLV_C14_Caspase3-7	462	466	PF00656	0.542
CLV_NRD_NRD_1	159	161	PF00675	0.275
CLV_NRD_NRD_1	28	30	PF00675	0.556
CLV_NRD_NRD_1	78	80	PF00675	0.630
CLV_PCSK_FUR_1	435	439	PF00082	0.303
CLV_PCSK_KEX2_1	161	163	PF00082	0.275
CLV_PCSK_KEX2_1	437	439	PF00082	0.303
CLV_PCSK_KEX2_1	78	80	PF00082	0.605
CLV_PCSK_KEX2_1	83	85	PF00082	0.594
CLV_PCSK_PC1ET2_1	161	163	PF00082	0.275
CLV_PCSK_PC1ET2_1	437	439	PF00082	0.323
CLV_PCSK_PC1ET2_1	83	85	PF00082	0.600
CLV_PCSK_PC7_1	79	85	PF00082	0.628
CLV_PCSK_SKI1_1	109	113	PF00082	0.551
CLV_PCSK_SKI1_1	179	183	PF00082	0.311
CLV_PCSK_SKI1_1	442	446	PF00082	0.360
CLV_PCSK_SKI1_1	467	471	PF00082	0.546
DEG_APCC_DBOX_1	198	206	PF00400	0.280
DEG_SCF_FBW7_1	31	38	PF00400	0.483
DEG_SPOP_SBC_1	18	22	PF00917	0.520
DEG_SPOP_SBC_1	48	52	PF00917	0.729
DOC_CYCLIN_RxL_1	138	148	PF00134	0.288
DOC_MAPK_gen_1	160	170	PF00069	0.281
DOC_MAPK_gen_1	176	185	PF00069	0.365
DOC_MAPK_gen_1	318	327	PF00069	0.288
DOC_MAPK_HePTP_8	315	327	PF00069	0.288
DOC_MAPK_MEF2A_6	179	187	PF00069	0.303
DOC_MAPK_MEF2A_6	318	327	PF00069	0.288
DOC_PP2B_LxvP_1	470	473	PF13499	0.516
DOC_PP4_MxPP_1	102	105	PF00568	0.535
DOC_SPAK_OSR1_1	139	143	PF12202	0.275
DOC_USP7_MATH_1	313	317	PF00917	0.303
DOC_USP7_MATH_1	35	39	PF00917	0.753
DOC_USP7_MATH_1	47	51	PF00917	0.633
DOC_USP7_MATH_1	62	66	PF00917	0.556
DOC_WW_Pin1_4	31	36	PF00397	0.612
DOC_WW_Pin1_4	319	324	PF00397	0.290
LIG_14-3-3_CanoR_1	387	396	PF00244	0.388
LIG_14-3-3_CanoR_1	397	402	PF00244	0.347
LIG_14-3-3_CanoR_1	442	448	PF00244	0.304
LIG_BIR_II_1	1	5	PF00653	0.653
LIG_deltaCOP1_diTrp_1	229	237	PF00928	0.323
LIG_EH1_1	139	147	PF00400	0.275
LIG_FHA_1	10	16	PF00498	0.513
LIG_FHA_1	110	116	PF00498	0.508
LIG_FHA_1	310	316	PF00498	0.303
LIG_FHA_1	347	353	PF00498	0.275
LIG_FHA_1	391	397	PF00498	0.233
LIG_FHA_1	55	61	PF00498	0.643
LIG_LIR_Apic_2	112	116	PF02991	0.474
LIG_LIR_Apic_2	317	323	PF02991	0.275
LIG_LIR_Gen_1	164	171	PF02991	0.275
LIG_LIR_Nem_3	122	128	PF02991	0.396
LIG_LIR_Nem_3	137	143	PF02991	0.373
LIG_LIR_Nem_3	148	154	PF02991	0.274
LIG_LIR_Nem_3	164	168	PF02991	0.275
LIG_PCNA_yPIPBox_3	95	109	PF02747	0.429
LIG_PTB_Apo_2	13	20	PF02174	0.501
LIG_PTB_Phospho_1	13	19	PF10480	0.500
LIG_SH2_CRK	113	117	PF00017	0.499
LIG_SH2_CRK	165	169	PF00017	0.275
LIG_SH2_PTP2	126	129	PF00017	0.369
LIG_SH2_STAP1	177	181	PF00017	0.275
LIG_SH2_STAP1	19	23	PF00017	0.611
LIG_SH2_STAP1	333	337	PF00017	0.303
LIG_SH2_STAT3	241	244	PF00017	0.173
LIG_SH2_STAT3	433	436	PF00017	0.323
LIG_SH2_STAT5	126	129	PF00017	0.386
LIG_SH2_STAT5	165	168	PF00017	0.275
LIG_SH2_STAT5	177	180	PF00017	0.275
LIG_SH2_STAT5	19	22	PF00017	0.686
LIG_SH2_STAT5	208	211	PF00017	0.284
LIG_SH2_STAT5	241	244	PF00017	0.413
LIG_SH2_STAT5	255	258	PF00017	0.298
LIG_SH2_STAT5	3	6	PF00017	0.475
LIG_SH2_STAT5	348	351	PF00017	0.380
LIG_SH2_STAT5	449	452	PF00017	0.358
LIG_SH3_1	287	293	PF00018	0.303
LIG_SH3_1	458	464	PF00018	0.422
LIG_SH3_2	290	295	PF14604	0.303
LIG_SH3_3	287	293	PF00018	0.277
LIG_SH3_3	458	464	PF00018	0.396
LIG_SH3_3	98	104	PF00018	0.651
LIG_UBA3_1	227	233	PF00899	0.275
LIG_UBA3_1	343	351	PF00899	0.303
MOD_CK1_1	89	95	PF00069	0.654
MOD_CK2_1	40	46	PF00069	0.552
MOD_CK2_1	67	73	PF00069	0.619
MOD_Cter_Amidation	76	79	PF01082	0.730
MOD_GlcNHglycan	212	215	PF01048	0.368
MOD_GlcNHglycan	278	281	PF01048	0.302
MOD_GlcNHglycan	79	82	PF01048	0.597
MOD_GSK3_1	309	316	PF00069	0.277
MOD_GSK3_1	31	38	PF00069	0.658
MOD_GSK3_1	332	339	PF00069	0.275
MOD_GSK3_1	372	379	PF00069	0.413
MOD_GSK3_1	49	56	PF00069	0.463
MOD_GSK3_1	58	65	PF00069	0.607
MOD_LATS_1	395	401	PF00433	0.173
MOD_N-GLC_1	210	215	PF02516	0.303
MOD_N-GLC_1	465	470	PF02516	0.547
MOD_NEK2_1	366	371	PF00069	0.293
MOD_NEK2_1	388	393	PF00069	0.332
MOD_NEK2_1	67	72	PF00069	0.682
MOD_PIKK_1	134	140	PF00454	0.365
MOD_PKA_1	109	115	PF00069	0.536
MOD_PKA_2	307	313	PF00069	0.303
MOD_PKA_2	77	83	PF00069	0.614
MOD_Plk_1	366	372	PF00069	0.275
MOD_Plk_1	465	471	PF00069	0.499
MOD_Plk_1	86	92	PF00069	0.769
MOD_Plk_4	141	147	PF00069	0.297
MOD_Plk_4	62	68	PF00069	0.631
MOD_ProDKin_1	31	37	PF00069	0.613
MOD_ProDKin_1	319	325	PF00069	0.290
MOD_SUMO_for_1	181	184	PF00179	0.303
MOD_SUMO_for_1	267	270	PF00179	0.275
TRG_DiLeu_BaEn_1	361	366	PF01217	0.275
TRG_DiLeu_BaEn_1	384	389	PF01217	0.368
TRG_DiLeu_BaEn_4	384	390	PF01217	0.323
TRG_DiLeu_LyEn_5	384	389	PF01217	0.368
TRG_ENDOCYTIC_2	126	129	PF00928	0.361
TRG_ENDOCYTIC_2	165	168	PF00928	0.275
TRG_ER_diArg_1	295	298	PF00400	0.318
TRG_ER_diArg_1	410	413	PF00400	0.288
TRG_NLS_MonoCore_2	106	111	PF00514	0.560
TRG_NLS_MonoExtN_4	104	111	PF00514	0.536
TRG_Pf-PMV_PEXEL_1	240	244	PF00026	0.275
TRG_Pf-PMV_PEXEL_1	287	292	PF00026	0.437

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2E2	Leptomonas seymouri	22%	100%
A0A0N0P2X9	Leptomonas seymouri	26%	100%
A0A0N0P4E3	Leptomonas seymouri	26%	71%
A0A0N1I0C1	Leptomonas seymouri	25%	100%
A0A0N1I3G0	Leptomonas seymouri	22%	100%
A0A0N1I9B7	Leptomonas seymouri	27%	100%
A0A0N1IHY4	Leptomonas seymouri	24%	100%
A0A0N1II59	Leptomonas seymouri	23%	100%
A0A0N1IIU9	Leptomonas seymouri	23%	100%
A0A0N1IL28	Leptomonas seymouri	23%	100%
A0A0S4IKY7	Bodo saltans	24%	100%
A0A0S4IL53	Bodo saltans	24%	70%
A0A0S4IUF2	Bodo saltans	27%	87%
A0A0S4IV16	Bodo saltans	24%	100%
A0A0S4IVF2	Bodo saltans	57%	100%
A0A0S4IVQ6	Bodo saltans	24%	100%
A0A0S4IYY9	Bodo saltans	57%	100%
A0A0S4J2K6	Bodo saltans	26%	100%
A0A0S4J343	Bodo saltans	24%	85%
A0A0S4J6A5	Bodo saltans	26%	100%
A0A0S4JCK3	Bodo saltans	24%	100%
A0A0S4JFM9	Bodo saltans	23%	100%
A0A0S4JKY3	Bodo saltans	30%	97%
A0A0S4JQ66	Bodo saltans	23%	100%
A0A0S4JUY0	Bodo saltans	31%	80%
A0A0S4JVD7	Bodo saltans	23%	100%
A0A0S4KHS0	Bodo saltans	27%	100%
A0A1X0NHA6	Trypanosomatidae	25%	90%
A0A1X0NLN7	Trypanosomatidae	25%	100%
A0A1X0NM44	Trypanosomatidae	26%	100%
A0A1X0NMR5	Trypanosomatidae	71%	96%
A0A1X0NMS0	Trypanosomatidae	72%	100%
A0A1X0NWR7	Trypanosomatidae	26%	93%
A0A1X0P020	Trypanosomatidae	26%	100%
A0A1X0P1E8	Trypanosomatidae	24%	100%
A0A1X0P1G1	Trypanosomatidae	26%	85%
A0A1X0P2I7	Trypanosomatidae	21%	100%
A0A1X0P3K5	Trypanosomatidae	27%	100%
A0A1X0P6E7	Trypanosomatidae	26%	100%
A0A1X0P6U6	Trypanosomatidae	28%	100%
A0A1X0P859	Trypanosomatidae	23%	100%
A0A1X0P8R6	Trypanosomatidae	22%	100%
A0A1X0P919	Trypanosomatidae	24%	100%
A0A3Q8IB74	Leishmania donovani	24%	100%
A0A3Q8IC55	Leishmania donovani	26%	95%
A0A3Q8IE25	Leishmania donovani	25%	72%
A0A3Q8II44	Leishmania donovani	24%	100%
A0A3Q8ITZ9	Leishmania donovani	22%	100%
A0A3Q8IVR8	Leishmania donovani	25%	100%
A0A3R7K5U6	Trypanosoma rangeli	26%	81%
A0A3R7K7W6	Trypanosoma rangeli	22%	100%
A0A3R7KDC2	Trypanosoma rangeli	25%	100%
A0A3R7KRL6	Trypanosoma rangeli	26%	100%
A0A3R7KRM5	Trypanosoma rangeli	28%	71%
A0A3R7L9Q6	Trypanosoma rangeli	21%	100%
A0A3R7LCG7	Trypanosoma rangeli	26%	82%
A0A3R7MKJ1	Trypanosoma rangeli	22%	88%
A0A3R7MWP2	Trypanosoma rangeli	26%	100%
A0A3S5H6C8	Leishmania donovani	90%	100%
A0A3S5H725	Leishmania donovani	22%	100%
A0A3S5H7N7	Leishmania donovani	22%	100%
A0A3S7WQK7	Leishmania donovani	85%	100%
A0A3S7WUE7	Leishmania donovani	23%	86%
A0A3S7X2Z6	Leishmania donovani	24%	100%
A0A3S7X9D1	Leishmania donovani	27%	83%
A0A3S7XA45	Leishmania donovani	25%	100%
A0A422N0M4	Trypanosoma rangeli	25%	100%
A0A422N7C9	Trypanosoma rangeli	85%	76%
A0A422N878	Trypanosoma rangeli	24%	91%
A0A422N9H2	Trypanosoma rangeli	24%	100%
A0A422NCX4	Trypanosoma rangeli	25%	100%
A0A422NL22	Trypanosoma rangeli	24%	79%
A0A422P2B2	Trypanosoma rangeli	24%	100%
A1CAF0	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	25%	100%
A1CPG7	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	25%	100%
A1D2C9	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	24%	100%
A1DES4	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	24%	100%
A1IVT7	Botryotinia fuckeliana (strain B05.10)	23%	100%
A2QN07	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	26%	100%
A2QRF6	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	24%	100%
A2XFC8	Oryza sativa subsp. indica	22%	100%
A2XUW1	Oryza sativa subsp. indica	26%	67%
A3EZ55	Wallemia ichthyophaga (strain EXF-994 / CBS 113033)	23%	100%
A3LN91	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	26%	100%
A4H436	Leishmania braziliensis	23%	100%
A4H4A1	Leishmania braziliensis	24%	100%
A4H641	Leishmania braziliensis	23%	100%
A4H9D1	Leishmania braziliensis	22%	100%
A4H9X5	Leishmania braziliensis	24%	100%
A4HA94	Leishmania braziliensis	28%	100%
A4HC27	Leishmania braziliensis	26%	95%
A4HFC9	Leishmania braziliensis	26%	72%
A4HIM5	Leishmania braziliensis	23%	100%
A4HLJ9	Leishmania braziliensis	21%	100%
A4HMK7	Leishmania braziliensis	27%	83%
A4HNG3	Leishmania braziliensis	25%	100%
A4HNT2	Leishmania braziliensis	24%	100%
A4HQG8	Leishmania braziliensis	23%	100%
A4HTV4	Leishmania infantum	85%	100%
A4HTV5	Leishmania infantum	90%	100%
A4HX71	Leishmania infantum	23%	86%
A4HXQ3	Leishmania infantum	22%	100%
A4HYH4	Leishmania infantum	27%	100%
A4HZH0	Leishmania infantum	26%	95%
A4I2K6	Leishmania infantum	25%	72%
A4I564	Leishmania infantum	24%	100%
A4I5X0	Leishmania infantum	22%	100%
A4I910	Leishmania infantum	22%	100%
A4IB86	Leishmania infantum	27%	83%
A4IC54	Leishmania infantum	25%	100%
A4ICA4	Leishmania infantum	24%	100%
A4ICR2	Leishmania infantum	25%	100%
A9S9Q8	Physcomitrium patens	24%	100%
A9T142	Physcomitrium patens	26%	100%
B0XR80	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)	24%	100%
B0Y462	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)	25%	100%
B0Y4X4	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)	24%	100%
B1H3E1	Xenopus tropicalis	24%	100%
B6DTC0	Bodo saltans	22%	100%
B6DTE5	Bodo saltans	25%	100%
B6DTK9	Bodo saltans	24%	100%
C9ZJ15	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	23%	100%
C9ZKU8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	82%
C9ZL78	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	23%	100%
C9ZNW1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	70%
C9ZR94	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	100%
C9ZUD1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	100%
C9ZVD8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	23%	100%
C9ZYF0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
D0A032	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	22%	100%
D0A0D6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
D0A0U8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	100%
D0A105	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	93%
D0A230	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	100%
D0A2P2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	100%
D0A3L9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	100%
D0A485	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	88%
D0A509	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	22%	100%
D0A813	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	98%
D0A820	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	100%
D0A9B7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	73%	100%
D3ZSZ3	Rattus norvegicus	24%	90%
E1BMN8	Bos taurus	24%	89%
E2QWQ2	Canis lupus familiaris	24%	90%
E8NHK0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
E8NHS0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
E9ACY7	Leishmania major	25%	72%
E9AF07	Leishmania major	27%	83%
E9AFX4	Leishmania major	23%	100%
E9AGS0	Leishmania infantum	24%	100%
E9AKG1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
E9AMP2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
E9ARC8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	86%
E9ARG4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	21%	100%
E9ARW9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9AS98	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9ASJ2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
E9AVG0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	95%
E9AYR2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	72%
E9B164	Leishmania mexicana (strain MHOM/GT/2001/U1103)	21%	100%
E9B663	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	83%
E9B727	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
G4N374	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	25%	100%
G4NH08	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	24%	100%
G5EBT1	Caenorhabditis elegans	23%	94%
M1T7M3	Wallemia ichthyophaga (strain EXF-994 / CBS 113033)	25%	100%
O02812	Canis lupus familiaris	25%	100%
O04160	Brassica napus	23%	100%
O08605	Mus musculus	25%	100%
O13352	Magnaporthe oryzae	25%	100%
O15264	Homo sapiens	27%	100%
O23236	Arabidopsis thaliana	24%	100%
O35491	Mus musculus	35%	95%
O35492	Mus musculus	34%	75%
O35493	Mus musculus	34%	99%
O42099	Cyprinus carpio	23%	100%
O43781	Homo sapiens	27%	81%
O44514	Caenorhabditis elegans	26%	100%
O54949	Mus musculus	24%	90%
O59853	Zygosaccharomyces rouxii	25%	100%
O59854	Zygosaccharomyces rouxii	25%	100%
O61443	Drosophila melanogaster	27%	100%
O93982	Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229)	25%	100%
O94547	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	21%	82%
P0C431	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	24%	100%
P0CP68	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	22%	100%
P0CP69	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	22%	100%
P11801	Homo sapiens	22%	100%
P14681	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	23%	100%
P16892	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	23%	100%
P18431	Drosophila melanogaster	22%	93%
P20793	Rattus norvegicus	26%	77%
P20794	Homo sapiens	25%	76%
P21708	Rattus norvegicus	25%	100%
P22518	Mus musculus	36%	99%
P26696	Xenopus laevis	25%	100%
P27361	Homo sapiens	25%	100%
P27638	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	22%	100%
P27704	Rattus norvegicus	24%	66%
P28482	Homo sapiens	26%	100%
P31152	Homo sapiens	23%	81%
P32485	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	100%
P38615	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	23%	100%
P39745	Caenorhabditis elegans	24%	100%
P40417	Drosophila melanogaster	24%	100%
P42525	Dictyostelium discoideum	26%	90%
P45983	Homo sapiens	23%	100%
P45984	Homo sapiens	24%	100%
P46196	Bos taurus	26%	100%
P47811	Mus musculus	26%	100%
P47812	Xenopus laevis	24%	100%
P49185	Rattus norvegicus	23%	100%
P49186	Rattus norvegicus	24%	100%
P49187	Rattus norvegicus	23%	100%
P49759	Homo sapiens	37%	98%
P49760	Homo sapiens	35%	95%
P49761	Homo sapiens	34%	75%
P51136	Dictyostelium discoideum	24%	100%
P51137	Medicago sativa	24%	100%
P51138	Medicago sativa	21%	100%
P51566	Arabidopsis thaliana	35%	100%
P51567	Arabidopsis thaliana	37%	100%
P51568	Arabidopsis thaliana	39%	100%
P53779	Homo sapiens	23%	100%
P63085	Mus musculus	26%	100%
P63086	Rattus norvegicus	26%	100%
P70618	Rattus norvegicus	25%	100%
P83101	Drosophila melanogaster	23%	95%
Q00532	Homo sapiens	24%	100%
Q00534	Homo sapiens	24%	100%
Q00772	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	98%
Q04859	Mus musculus	26%	77%
Q06060	Pisum sativum	25%	100%
Q07176	Medicago sativa	25%	100%
Q07538	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	27%	100%
Q09892	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	24%	100%
Q0CIC7	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	24%	100%
Q0D0P5	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	24%	100%
Q0U4L8	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	25%	100%
Q0V7M1	Bos taurus	22%	100%
Q10156	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	69%
Q10N20	Oryza sativa subsp. japonica	22%	100%
Q11179	Caenorhabditis elegans	23%	100%
Q12222	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	23%	100%
Q15759	Homo sapiens	25%	100%
Q16539	Homo sapiens	26%	100%
Q16659	Homo sapiens	24%	66%
Q1DUU8	Coccidioides immitis (strain RS)	24%	100%
Q1KTF2	Zymoseptoria tritici (strain CBS 115943 / IPO323)	23%	100%
Q1L5Z8	Torulaspora delbrueckii	25%	100%
Q2H332	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	23%	100%
Q2U469	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	26%	100%
Q2WFL5	Cochliobolus miyabeanus	25%	100%
Q2WGK3	Trichoderma harzianum	24%	100%
Q336X9	Oryza sativa subsp. japonica	24%	100%
Q39021	Arabidopsis thaliana	23%	100%
Q39022	Arabidopsis thaliana	23%	100%
Q39023	Arabidopsis thaliana	23%	100%
Q39024	Arabidopsis thaliana	24%	100%
Q39025	Arabidopsis thaliana	24%	100%
Q39026	Arabidopsis thaliana	24%	100%
Q39027	Arabidopsis thaliana	23%	100%
Q3S406	Magnaporthe oryzae	24%	100%
Q3SX21	Bos taurus	34%	97%
Q3T0N5	Bos taurus	27%	100%
Q40353	Medicago sativa	25%	100%
Q40517	Nicotiana tabacum	24%	100%
Q40518	Nicotiana tabacum	22%	100%
Q40531	Nicotiana tabacum	25%	100%
Q40532	Nicotiana tabacum	24%	100%
Q40884	Petunia hybrida	24%	100%
Q45FA5	Physarum polycephalum	29%	100%
Q4G050	Rattus norvegicus	25%	100%
Q4PC06	Ustilago maydis (strain 521 / FGSC 9021)	25%	100%
Q4Q0B0	Leishmania major	23%	100%
Q4Q204	Leishmania major	24%	100%
Q4Q449	Leishmania major	22%	100%
Q4Q701	Leishmania major	23%	100%
Q4QC19	Leishmania major	26%	100%
Q4QD66	Leishmania major	27%	100%
Q4QDK3	Leishmania major	24%	100%
Q4QE15	Leishmania major	22%	100%
Q4QEJ2	Leishmania major	23%	86%
Q4QFG6	Leishmania major	27%	100%
Q4QHY3	Leishmania major	92%	100%
Q4QHY4	Leishmania major	89%	100%
Q4QJE7	Leishmania major	24%	100%
Q4R6S5	Macaca fascicularis	27%	84%
Q4V8A3	Rattus norvegicus	27%	81%
Q4W6D3	Cochliobolus heterostrophus	25%	100%
Q4WQR3	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	24%	100%
Q4WSF6	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	24%	100%
Q4WUN7	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	24%	100%
Q501Q9	Xenopus laevis	26%	81%
Q501V0	Danio rerio	22%	100%
Q52PH6	Alternaria brassicicola	24%	100%
Q53N72	Oryza sativa subsp. japonica	25%	96%
Q54QB1	Dictyostelium discoideum	22%	100%
Q54Y06	Dictyostelium discoideum	25%	75%
Q55FJ6	Dictyostelium discoideum	23%	94%
Q56R42	Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)	22%	100%
Q58D94	Bos taurus	26%	100%
Q5J4W4	Oryza sativa subsp. japonica	23%	100%
Q5SN53	Oryza sativa subsp. japonica	26%	84%
Q5U4C9	Mus musculus	28%	79%
Q5VP69	Oryza sativa subsp. japonica	24%	95%
Q5Z859	Oryza sativa subsp. japonica	25%	100%
Q5Z9J0	Oryza sativa subsp. japonica	26%	82%
Q5ZIU3	Gallus gallus	25%	90%
Q61532	Mus musculus	24%	66%
Q61831	Mus musculus	23%	100%
Q63117	Rattus norvegicus	34%	97%
Q63844	Mus musculus	25%	100%
Q64261	Mus musculus	24%	100%
Q66JF3	Xenopus tropicalis	25%	100%
Q6AXJ9	Danio rerio	23%	100%
Q6C4M9	Yarrowia lipolytica (strain CLIB 122 / E 150)	25%	100%
Q6CJA8	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	25%	100%
Q6FIU2	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	25%	100%
Q6FV07	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	23%	100%
Q6L5F7	Oryza sativa subsp. japonica	26%	82%
Q6P5G0	Mus musculus	24%	82%
Q6PWX2	Beauveria bassiana	24%	100%
Q6XKY3	Hypocrea atroviridis	24%	100%
Q6Z437	Oryza sativa subsp. japonica	24%	100%
Q702W0	Blastobotrys adeninivorans	25%	100%
Q750A9	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	25%	100%
Q75KK8	Oryza sativa subsp. japonica	24%	88%
Q75Q66	Colletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422)	23%	100%
Q7XUF4	Oryza sativa subsp. japonica	26%	67%
Q80Y86	Mus musculus	27%	87%
Q84UI5	Oryza sativa subsp. japonica	26%	100%
Q871M9	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	26%	85%
Q875L0	Cryphonectria parasitica	24%	100%
Q8BI55	Mus musculus	28%	75%
Q8BLF2	Mus musculus	24%	80%
Q8GYQ5	Arabidopsis thaliana	23%	100%
Q8NJT7	Hortaea werneckii	24%	100%
Q8QGV6	Xenopus laevis	24%	100%
Q8QHK8	Xenopus laevis	23%	100%
Q8SQZ4	Encephalitozoon cuniculi (strain GB-M1)	28%	100%
Q8TD08	Homo sapiens	26%	88%
Q8TGA9	Blumeria graminis	23%	100%
Q8VZD5	Arabidopsis thaliana	23%	100%
Q8W4J2	Arabidopsis thaliana	26%	84%
Q8WQG9	Caenorhabditis elegans	26%	100%
Q90327	Cyprinus carpio	23%	100%
Q90336	Cyprinus carpio	26%	100%
Q91Y86	Mus musculus	23%	100%
Q91YA2	Mus musculus	22%	100%
Q92207	Candida albicans (strain SC5314 / ATCC MYA-2876)	27%	100%
Q922Y0	Mus musculus	27%	81%
Q92630	Homo sapiens	28%	79%
Q95NE7	Pan troglodytes	26%	100%
Q966Y3	Suberites domuncula	25%	100%
Q96QS6	Homo sapiens	24%	100%
Q96TL5	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	23%	100%
Q96VK3	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	26%	88%
Q99078	Ustilago maydis (strain 521 / FGSC 9021)	24%	100%
Q9C9U4	Arabidopsis thaliana	23%	83%
Q9DGD9	Danio rerio	23%	100%
Q9DGE1	Danio rerio	27%	100%
Q9DGE2	Danio rerio	26%	100%
Q9FGW5	Arabidopsis thaliana	25%	78%
Q9FVS6	Arabidopsis thaliana	22%	100%
Q9GRU1	Leishmania mexicana	27%	100%
Q9HAZ1	Homo sapiens	34%	99%
Q9HG11	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	25%	100%
Q9I958	Cyprinus carpio	25%	100%
Q9JM01	Rattus norvegicus	24%	80%
Q9LMM5	Arabidopsis thaliana	24%	100%
Q9LQQ9	Arabidopsis thaliana	21%	100%
Q9M1Z5	Arabidopsis thaliana	24%	100%
Q9N272	Pan troglodytes	26%	100%
Q9NR20	Homo sapiens	28%	92%
Q9P419	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	23%	100%
Q9U2H1	Caenorhabditis elegans	24%	100%
Q9U6D2	Ancylostoma caninum	26%	100%
Q9U6V4	Leishmania donovani	27%	100%
Q9U9Y8	Caenorhabditis elegans	25%	75%
Q9UBE8	Homo sapiens	24%	90%
Q9UPZ9	Homo sapiens	24%	75%
Q9UQ07	Homo sapiens	22%	100%
Q9UV50	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	26%	100%
Q9UV51	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	23%	100%
Q9WTU6	Mus musculus	24%	100%
Q9WUI1	Mus musculus	25%	100%
Q9WVS4	Mus musculus	22%	100%
Q9Z2A6	Rattus norvegicus	26%	87%
V5B6E9	Trypanosoma cruzi	23%	100%
V5B8S3	Trypanosoma cruzi	24%	100%
V5B8U8	Trypanosoma cruzi	27%	100%
V5B9Y9	Trypanosoma cruzi	23%	100%
V5BCX5	Trypanosoma cruzi	22%	100%
V5BH88	Trypanosoma cruzi	22%	87%
V5BJT8	Trypanosoma cruzi	24%	100%
V5BLT9	Trypanosoma cruzi	21%	100%
V5BN23	Trypanosoma cruzi	74%	97%
V5BPE2	Trypanosoma cruzi	25%	100%
V5BSG8	Trypanosoma cruzi	25%	100%
V5DCD4	Trypanosoma cruzi	25%	81%
V5DDT1	Trypanosoma cruzi	24%	100%
V5DIC3	Trypanosoma cruzi	25%	79%
V5DTI8	Trypanosoma cruzi	25%	100%