Putative RNA-binding protein 5

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

RNA-binding protein 5, putative

Species:

Leishmania braziliensis

UniProt:

A4H5I3_LEIBR

TriTrypDb:

LbrM.09.0080 , LBRM2903_090005700

Length:

131

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H5I3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H5I3

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	12
GO:0003723	RNA binding	4	12
GO:0005488	binding	1	12
GO:0097159	organic cyclic compound binding	2	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	23	27	PF00082	0.320
CLV_PCSK_SKI1_1	34	38	PF00082	0.277
DOC_MAPK_gen_1	76	84	PF00069	0.527
DOC_MAPK_gen_1	92	99	PF00069	0.440
DOC_MAPK_MEF2A_6	76	84	PF00069	0.529
DOC_USP7_MATH_1	63	67	PF00917	0.462
DOC_USP7_MATH_1	87	91	PF00917	0.445
DOC_USP7_UBL2_3	41	45	PF12436	0.376
DOC_WW_Pin1_4	117	122	PF00397	0.567
DOC_WW_Pin1_4	2	7	PF00397	0.473
DOC_WW_Pin1_4	27	32	PF00397	0.491
LIG_14-3-3_CanoR_1	34	42	PF00244	0.529
LIG_BIR_II_1	1	5	PF00653	0.508
LIG_eIF4E_1	20	26	PF01652	0.535
LIG_FHA_1	35	41	PF00498	0.386
LIG_FHA_1	6	12	PF00498	0.426
LIG_LIR_Apic_2	2	6	PF02991	0.483
LIG_LIR_Gen_1	120	129	PF02991	0.493
LIG_LIR_Nem_3	120	126	PF02991	0.489
LIG_LIR_Nem_3	27	32	PF02991	0.490
LIG_LYPXL_S_1	94	98	PF13949	0.524
LIG_LYPXL_yS_3	95	98	PF13949	0.525
LIG_SH2_CRK	110	114	PF00017	0.617
LIG_SH2_CRK	123	127	PF00017	0.615
LIG_SH2_CRK	52	56	PF00017	0.431
LIG_SH2_SRC	110	113	PF00017	0.625
LIG_SH2_SRC	117	120	PF00017	0.610
LIG_SH2_STAT5	114	117	PF00017	0.539
LIG_SH2_STAT5	12	15	PF00017	0.463
LIG_SH3_3	106	112	PF00018	0.548
LIG_SH3_3	115	121	PF00018	0.508
LIG_SUMO_SIM_par_1	24	30	PF11976	0.535
MOD_CDK_SPxxK_3	2	9	PF00069	0.455
MOD_CDK_SPxxK_3	27	34	PF00069	0.491
MOD_CK1_1	124	130	PF00069	0.424
MOD_CK1_1	2	8	PF00069	0.456
MOD_GlcNHglycan	104	107	PF01048	0.425
MOD_GlcNHglycan	88	92	PF01048	0.467
MOD_GSK3_1	117	124	PF00069	0.600
MOD_GSK3_1	71	78	PF00069	0.474
MOD_PIKK_1	121	127	PF00454	0.501
MOD_PKA_2	75	81	PF00069	0.529
MOD_Plk_4	63	69	PF00069	0.396
MOD_ProDKin_1	117	123	PF00069	0.568
MOD_ProDKin_1	2	8	PF00069	0.464
MOD_ProDKin_1	27	33	PF00069	0.491
TRG_ENDOCYTIC_2	110	113	PF00928	0.448
TRG_ENDOCYTIC_2	123	126	PF00928	0.466
TRG_ENDOCYTIC_2	52	55	PF00928	0.431
TRG_ENDOCYTIC_2	95	98	PF00928	0.504

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HTR1	Leptomonas seymouri	86%	99%
A0A1X0NNG9	Trypanosomatidae	59%	100%
A0A3R7KCI5	Trypanosoma rangeli	56%	100%
A0A3S5H6A7	Leishmania donovani	89%	100%
A4HTS4	Leishmania infantum	89%	100%
D0A984	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	56%	100%
E9AMK7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
Q4QI29	Leishmania major	87%	100%
V5BIJ7	Trypanosoma cruzi	59%	100%
V5BSY3	Trypanosoma cruzi	32%	66%