Protein kinase domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H5C0_LEIBR

TriTrypDb:

LbrM.08.0560 , LBRM2903_080011600

Length:

439

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H5C0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H5C0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	189	193	PF00656	0.799
CLV_C14_Caspase3-7	375	379	PF00656	0.845
CLV_NRD_NRD_1	139	141	PF00675	0.877
CLV_NRD_NRD_1	14	16	PF00675	0.873
CLV_NRD_NRD_1	349	351	PF00675	0.792
CLV_NRD_NRD_1	66	68	PF00675	0.847
CLV_PCSK_KEX2_1	139	141	PF00082	0.877
CLV_PCSK_KEX2_1	14	16	PF00082	0.873
CLV_PCSK_KEX2_1	349	351	PF00082	0.792
CLV_PCSK_KEX2_1	66	68	PF00082	0.847
CLV_PCSK_SKI1_1	139	143	PF00082	0.881
CLV_PCSK_SKI1_1	361	365	PF00082	0.786
CLV_PCSK_SKI1_1	421	425	PF00082	0.797
DEG_COP1_1	262	272	PF00400	0.798
DEG_Nend_Nbox_1	1	3	PF02207	0.855
DEG_SPOP_SBC_1	371	375	PF00917	0.835
DEG_SPOP_SBC_1	38	42	PF00917	0.880
DOC_MAPK_RevD_3	335	350	PF00069	0.731
DOC_PP1_RVXF_1	307	313	PF00149	0.816
DOC_USP7_MATH_1	31	35	PF00917	0.870
DOC_USP7_MATH_1	36	40	PF00917	0.786
DOC_USP7_MATH_1	371	375	PF00917	0.835
DOC_USP7_MATH_1	401	405	PF00917	0.840
DOC_USP7_MATH_1	423	427	PF00917	0.797
DOC_USP7_MATH_1	87	91	PF00917	0.861
DOC_WW_Pin1_4	112	117	PF00397	0.864
DOC_WW_Pin1_4	18	23	PF00397	0.862
DOC_WW_Pin1_4	201	206	PF00397	0.880
DOC_WW_Pin1_4	341	346	PF00397	0.739
LIG_14-3-3_CanoR_1	107	113	PF00244	0.865
LIG_14-3-3_CanoR_1	361	368	PF00244	0.795
LIG_14-3-3_CanoR_1	425	429	PF00244	0.800
LIG_FHA_1	230	236	PF00498	0.848
LIG_FHA_1	50	56	PF00498	0.854
LIG_FHA_2	170	176	PF00498	0.756
LIG_FHA_2	373	379	PF00498	0.842
LIG_IRF3_LxIS_1	102	109	PF10401	0.854
LIG_LIR_Gen_1	157	168	PF02991	0.783
LIG_LIR_Gen_1	332	343	PF02991	0.707
LIG_LIR_Nem_3	157	163	PF02991	0.789
LIG_LIR_Nem_3	332	338	PF02991	0.714
LIG_NRBOX	178	184	PF00104	0.728
LIG_PCNA_yPIPBox_3	154	163	PF02747	0.799
LIG_PDZ_Class_2	434	439	PF00595	0.805
LIG_SH2_NCK_1	331	335	PF00017	0.732
LIG_SH2_STAP1	160	164	PF00017	0.781
LIG_SH2_STAP1	261	265	PF00017	0.772
LIG_SH2_STAP1	331	335	PF00017	0.732
LIG_SH2_STAT5	331	334	PF00017	0.738
LIG_SH3_3	16	22	PF00018	0.867
LIG_SH3_3	30	36	PF00018	0.623
LIG_SUMO_SIM_anti_2	52	58	PF11976	0.854
LIG_WRC_WIRS_1	70	75	PF05994	0.853
LIG_WW_3	102	106	PF00397	0.848
MOD_CDK_SPxK_1	201	207	PF00069	0.881
MOD_CK1_1	132	138	PF00069	0.882
MOD_CK1_1	203	209	PF00069	0.885
MOD_CK1_1	341	347	PF00069	0.741
MOD_CK1_1	370	376	PF00069	0.837
MOD_CK1_1	39	45	PF00069	0.880
MOD_CK1_1	404	410	PF00069	0.818
MOD_CK1_1	71	77	PF00069	0.851
MOD_CK1_1	90	96	PF00069	0.531
MOD_CK2_1	261	267	PF00069	0.779
MOD_CK2_1	69	75	PF00069	0.853
MOD_Cter_Amidation	137	140	PF01082	0.877
MOD_Cter_Amidation	64	67	PF01082	0.846
MOD_GlcNHglycan	135	138	PF01048	0.877
MOD_GlcNHglycan	253	256	PF01048	0.699
MOD_GlcNHglycan	269	272	PF01048	0.540
MOD_GlcNHglycan	282	285	PF01048	0.601
MOD_GlcNHglycan	351	354	PF01048	0.785
MOD_GlcNHglycan	369	372	PF01048	0.516
MOD_GlcNHglycan	403	406	PF01048	0.833
MOD_GlcNHglycan	410	413	PF01048	0.675
MOD_GlcNHglycan	42	45	PF01048	0.880
MOD_GSK3_1	108	115	PF00069	0.866
MOD_GSK3_1	129	136	PF00069	0.879
MOD_GSK3_1	150	157	PF00069	0.833
MOD_GSK3_1	171	178	PF00069	0.760
MOD_GSK3_1	199	206	PF00069	0.876
MOD_GSK3_1	209	216	PF00069	0.704
MOD_GSK3_1	227	234	PF00069	0.542
MOD_GSK3_1	36	43	PF00069	0.876
MOD_GSK3_1	367	374	PF00069	0.828
MOD_GSK3_1	404	411	PF00069	0.815
MOD_GSK3_1	87	94	PF00069	0.863
MOD_N-GLC_1	116	121	PF02516	0.868
MOD_N-GLC_1	132	137	PF02516	0.602
MOD_N-GLC_1	219	224	PF02516	0.875
MOD_N-GLC_1	280	285	PF02516	0.831
MOD_N-GLC_1	91	96	PF02516	0.866
MOD_NEK2_1	106	111	PF00069	0.860
MOD_NEK2_1	214	219	PF00069	0.876
MOD_NEK2_1	240	245	PF00069	0.799
MOD_NEK2_1	424	429	PF00069	0.800
MOD_NEK2_2	116	121	PF00069	0.868
MOD_PIKK_1	209	215	PF00454	0.879
MOD_PIKK_1	355	361	PF00454	0.768
MOD_PIKK_1	429	435	PF00454	0.793
MOD_PIKK_1	92	98	PF00454	0.868
MOD_PKA_1	139	145	PF00069	0.883
MOD_PKA_1	349	355	PF00069	0.788
MOD_PKA_2	106	112	PF00069	0.861
MOD_PKA_2	139	145	PF00069	0.883
MOD_PKA_2	206	212	PF00069	0.885
MOD_PKA_2	349	355	PF00069	0.788
MOD_PKA_2	424	430	PF00069	0.798
MOD_PKB_1	105	113	PF00069	0.862
MOD_Plk_1	261	267	PF00069	0.779
MOD_Plk_1	74	80	PF00069	0.849
MOD_Plk_4	338	344	PF00069	0.699
MOD_Plk_4	424	430	PF00069	0.798
MOD_Plk_4	50	56	PF00069	0.854
MOD_Plk_4	74	80	PF00069	0.849
MOD_ProDKin_1	112	118	PF00069	0.866
MOD_ProDKin_1	18	24	PF00069	0.862
MOD_ProDKin_1	201	207	PF00069	0.881
MOD_ProDKin_1	341	347	PF00069	0.741
TRG_ENDOCYTIC_2	160	163	PF00928	0.781
TRG_ER_diArg_1	104	107	PF00400	0.856
TRG_ER_diArg_1	139	141	PF00400	0.877
TRG_ER_diArg_1	14	16	PF00400	0.873
TRG_ER_diArg_1	309	312	PF00400	0.821
TRG_ER_diArg_1	349	351	PF00400	0.792
TRG_ER_diArg_1	396	399	PF00400	0.840
TRG_Pf-PMV_PEXEL_1	166	171	PF00026	0.764