Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4H5B7_LEIBR

TriTrypDb:

LbrM.08.0530 , LBRM2903_080011800

Length:

381

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H5B7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H5B7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	119	123	PF00656	0.723
CLV_NRD_NRD_1	16	18	PF00675	0.663
CLV_NRD_NRD_1	216	218	PF00675	0.610
CLV_NRD_NRD_1	273	275	PF00675	0.677
CLV_NRD_NRD_1	4	6	PF00675	0.712
CLV_NRD_NRD_1	62	64	PF00675	0.680
CLV_PCSK_KEX2_1	139	141	PF00082	0.559
CLV_PCSK_KEX2_1	215	217	PF00082	0.763
CLV_PCSK_KEX2_1	273	275	PF00082	0.677
CLV_PCSK_KEX2_1	62	64	PF00082	0.554
CLV_PCSK_PC1ET2_1	139	141	PF00082	0.559
CLV_PCSK_PC1ET2_1	62	64	PF00082	0.554
CLV_PCSK_SKI1_1	18	22	PF00082	0.682
CLV_PCSK_SKI1_1	267	271	PF00082	0.680
CLV_PCSK_SKI1_1	355	359	PF00082	0.470
CLV_PCSK_SKI1_1	59	63	PF00082	0.558
CLV_PCSK_SKI1_1	68	72	PF00082	0.539
CLV_PCSK_SKI1_1	96	100	PF00082	0.474
DEG_APCC_DBOX_1	332	340	PF00400	0.681
DEG_APCC_DBOX_1	368	376	PF00400	0.562
DEG_APCC_DBOX_1	90	98	PF00400	0.675
DEG_SIAH_1	151	159	PF03145	0.559
DEG_SPOP_SBC_1	364	368	PF00917	0.478
DOC_ANK_TNKS_1	142	149	PF00023	0.573
DOC_MAPK_DCC_7	369	377	PF00069	0.477
DOC_USP7_MATH_1	152	156	PF00917	0.609
DOC_USP7_MATH_1	159	163	PF00917	0.692
DOC_USP7_MATH_1	232	236	PF00917	0.559
DOC_USP7_MATH_1	340	344	PF00917	0.519
DOC_WW_Pin1_4	113	118	PF00397	0.610
DOC_WW_Pin1_4	195	200	PF00397	0.760
DOC_WW_Pin1_4	246	251	PF00397	0.731
DOC_WW_Pin1_4	30	35	PF00397	0.832
DOC_WW_Pin1_4	303	308	PF00397	0.557
DOC_WW_Pin1_4	370	375	PF00397	0.481
DOC_WW_Pin1_4	39	44	PF00397	0.681
LIG_14-3-3_CanoR_1	274	280	PF00244	0.574
LIG_14-3-3_CanoR_1	355	364	PF00244	0.643
LIG_14-3-3_CanoR_1	65	71	PF00244	0.716
LIG_14-3-3_CanoR_1	76	82	PF00244	0.674
LIG_14-3-3_CanoR_1	96	103	PF00244	0.524
LIG_deltaCOP1_diTrp_1	263	269	PF00928	0.655
LIG_eIF4E_1	103	109	PF01652	0.667
LIG_FHA_1	151	157	PF00498	0.562
LIG_FHA_1	164	170	PF00498	0.723
LIG_FHA_1	228	234	PF00498	0.557
LIG_FHA_1	356	362	PF00498	0.503
LIG_FHA_1	90	96	PF00498	0.505
LIG_FHA_2	114	120	PF00498	0.553
LIG_FHA_2	344	350	PF00498	0.649
LIG_FHA_2	78	84	PF00498	0.564
LIG_LIR_Nem_3	173	177	PF02991	0.703
LIG_LIR_Nem_3	263	269	PF02991	0.663
LIG_PCNA_PIPBox_1	350	359	PF02747	0.461
LIG_PDZ_Class_3	376	381	PF00595	0.657
LIG_SH2_NCK_1	103	107	PF00017	0.661
LIG_SH2_STAT5	103	106	PF00017	0.663
LIG_SH2_STAT5	356	359	PF00017	0.648
LIG_SH3_2	16	21	PF14604	0.738
LIG_SH3_3	13	19	PF00018	0.713
LIG_SH3_3	244	250	PF00018	0.554
LIG_SH3_3	52	58	PF00018	0.575
LIG_SH3_4	18	25	PF00018	0.583
LIG_TRAF2_1	98	101	PF00917	0.651
MOD_CK1_1	208	214	PF00069	0.614
MOD_CK1_1	288	294	PF00069	0.578
MOD_CK1_1	301	307	PF00069	0.524
MOD_CK1_1	343	349	PF00069	0.480
MOD_CK1_1	42	48	PF00069	0.724
MOD_CK1_1	69	75	PF00069	0.730
MOD_CK1_1	77	83	PF00069	0.624
MOD_CK2_1	170	176	PF00069	0.686
MOD_CK2_1	343	349	PF00069	0.662
MOD_CK2_1	77	83	PF00069	0.588
MOD_Cter_Amidation	213	216	PF01082	0.765
MOD_DYRK1A_RPxSP_1	30	34	PF00069	0.691
MOD_GlcNHglycan	206	210	PF01048	0.598
MOD_GlcNHglycan	234	237	PF01048	0.593
MOD_GlcNHglycan	259	262	PF01048	0.532
MOD_GlcNHglycan	292	295	PF01048	0.621
MOD_GlcNHglycan	316	319	PF01048	0.580
MOD_GSK3_1	1	8	PF00069	0.573
MOD_GSK3_1	159	166	PF00069	0.729
MOD_GSK3_1	204	211	PF00069	0.711
MOD_GSK3_1	273	280	PF00069	0.642
MOD_GSK3_1	284	291	PF00069	0.620
MOD_GSK3_1	30	37	PF00069	0.719
MOD_GSK3_1	339	346	PF00069	0.770
MOD_GSK3_1	360	367	PF00069	0.478
MOD_GSK3_1	38	45	PF00069	0.739
MOD_GSK3_1	66	73	PF00069	0.674
MOD_GSK3_1	77	84	PF00069	0.715
MOD_GSK3_1	85	92	PF00069	0.665
MOD_LATS_1	272	278	PF00433	0.524
MOD_N-GLC_1	204	209	PF02516	0.585
MOD_N-GLC_1	301	306	PF02516	0.566
MOD_N-GLC_1	84	89	PF02516	0.556
MOD_NEK2_1	227	232	PF00069	0.555
MOD_NEK2_1	339	344	PF00069	0.602
MOD_PIKK_1	10	16	PF00454	0.580
MOD_PIKK_1	163	169	PF00454	0.573
MOD_PIKK_1	96	102	PF00454	0.673
MOD_PKA_1	139	145	PF00069	0.565
MOD_PKA_1	273	279	PF00069	0.681
MOD_PKA_1	5	11	PF00069	0.582
MOD_PKA_2	139	145	PF00069	0.615
MOD_PKA_2	273	279	PF00069	0.681
MOD_PKA_2	280	286	PF00069	0.652
MOD_Plk_1	159	165	PF00069	0.607
MOD_Plk_1	74	80	PF00069	0.590
MOD_Plk_1	85	91	PF00069	0.471
MOD_Plk_2-3	170	176	PF00069	0.602
MOD_Plk_4	104	110	PF00069	0.615
MOD_Plk_4	159	165	PF00069	0.558
MOD_Plk_4	254	260	PF00069	0.587
MOD_Plk_4	340	346	PF00069	0.503
MOD_ProDKin_1	113	119	PF00069	0.614
MOD_ProDKin_1	195	201	PF00069	0.763
MOD_ProDKin_1	246	252	PF00069	0.727
MOD_ProDKin_1	30	36	PF00069	0.833
MOD_ProDKin_1	303	309	PF00069	0.556
MOD_ProDKin_1	370	376	PF00069	0.481
MOD_ProDKin_1	39	45	PF00069	0.682
TRG_DiLeu_BaLyEn_6	107	112	PF01217	0.690
TRG_DiLeu_BaLyEn_6	56	61	PF01217	0.556
TRG_ENDOCYTIC_2	174	177	PF00928	0.671
TRG_ER_diArg_1	215	217	PF00400	0.581
TRG_ER_diArg_1	333	336	PF00400	0.711
TRG_NLS_MonoCore_2	61	66	PF00514	0.559
TRG_NLS_MonoExtN_4	59	66	PF00514	0.626

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H654	Leishmania donovani	50%	100%
A4HTJ8	Leishmania infantum	49%	100%
E9AMC9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	50%	100%
Q4QIB9	Leishmania major	50%	91%