Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H5B3_LEIBR

TriTrypDb:

LbrM.08.0490 , LBRM2903_080012700

Length:

465

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H5B3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H5B3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	1	3	PF00675	0.771
CLV_NRD_NRD_1	142	144	PF00675	0.741
CLV_NRD_NRD_1	18	20	PF00675	0.475
CLV_NRD_NRD_1	238	240	PF00675	0.854
CLV_NRD_NRD_1	243	245	PF00675	0.786
CLV_NRD_NRD_1	330	332	PF00675	0.736
CLV_NRD_NRD_1	8	10	PF00675	0.612
CLV_PCSK_FUR_1	236	240	PF00082	0.854
CLV_PCSK_KEX2_1	141	143	PF00082	0.748
CLV_PCSK_KEX2_1	18	20	PF00082	0.597
CLV_PCSK_KEX2_1	238	240	PF00082	0.854
CLV_PCSK_KEX2_1	243	245	PF00082	0.786
CLV_PCSK_KEX2_1	294	296	PF00082	0.878
CLV_PCSK_KEX2_1	319	321	PF00082	0.672
CLV_PCSK_KEX2_1	330	332	PF00082	0.543
CLV_PCSK_KEX2_1	37	39	PF00082	0.381
CLV_PCSK_KEX2_1	8	10	PF00082	0.735
CLV_PCSK_PC1ET2_1	294	296	PF00082	0.878
CLV_PCSK_PC1ET2_1	319	321	PF00082	0.672
CLV_PCSK_PC1ET2_1	37	39	PF00082	0.714
CLV_PCSK_PC7_1	239	245	PF00082	0.866
CLV_PCSK_PC7_1	290	296	PF00082	0.875
CLV_PCSK_PC7_1	315	321	PF00082	0.675
CLV_PCSK_SKI1_1	143	147	PF00082	0.731
CLV_PCSK_SKI1_1	295	299	PF00082	0.867
CLV_PCSK_SKI1_1	350	354	PF00082	0.665
DEG_Nend_UBRbox_1	1	4	PF02207	0.761
DEG_SCF_FBW7_2	457	464	PF00400	0.821
DEG_SPOP_SBC_1	108	112	PF00917	0.810
DEG_SPOP_SBC_1	445	449	PF00917	0.810
DOC_ANK_TNKS_1	411	418	PF00023	0.823
DOC_CYCLIN_RxL_1	346	354	PF00134	0.665
DOC_MAPK_gen_1	35	45	PF00069	0.725
DOC_MAPK_MEF2A_6	363	370	PF00069	0.763
DOC_MAPK_MEF2A_6	37	46	PF00069	0.728
DOC_MAPK_NFAT4_5	363	371	PF00069	0.758
DOC_USP7_MATH_1	100	104	PF00917	0.792
DOC_USP7_MATH_1	108	112	PF00917	0.670
DOC_USP7_MATH_1	172	176	PF00917	0.825
DOC_USP7_MATH_1	222	226	PF00917	0.822
DOC_USP7_MATH_1	308	312	PF00917	0.818
DOC_USP7_MATH_1	318	322	PF00917	0.480
DOC_USP7_MATH_1	369	373	PF00917	0.766
DOC_USP7_MATH_1	408	412	PF00917	0.827
DOC_USP7_MATH_1	416	420	PF00917	0.677
DOC_USP7_MATH_2	436	442	PF00917	0.816
DOC_USP7_UBL2_3	31	35	PF12436	0.744
DOC_WW_Pin1_4	457	462	PF00397	0.820
LIG_14-3-3_CanoR_1	153	162	PF00244	0.799
LIG_14-3-3_CanoR_1	213	218	PF00244	0.865
LIG_14-3-3_CanoR_1	243	250	PF00244	0.866
LIG_14-3-3_CanoR_1	265	270	PF00244	0.860
LIG_14-3-3_CanoR_1	363	369	PF00244	0.762
LIG_14-3-3_CanoR_1	386	392	PF00244	0.672
LIG_14-3-3_CanoR_1	56	61	PF00244	0.795
LIG_14-3-3_CanoR_1	82	86	PF00244	0.739
LIG_Actin_WH2_2	375	390	PF00022	0.701
LIG_BRCT_BRCA1_1	102	106	PF00533	0.802
LIG_FHA_1	102	108	PF00498	0.801
LIG_FHA_1	162	168	PF00498	0.820
LIG_FHA_1	56	62	PF00498	0.789
LIG_FHA_2	446	452	PF00498	0.808
LIG_FHA_2	65	71	PF00498	0.726
LIG_LIR_Apic_2	24	30	PF02991	0.763
LIG_LIR_Gen_1	62	72	PF02991	0.737
LIG_LIR_Gen_1	77	87	PF02991	0.467
LIG_LIR_Gen_1	92	100	PF02991	0.512
LIG_LIR_Nem_3	144	149	PF02991	0.736
LIG_LIR_Nem_3	225	230	PF02991	0.825
LIG_LIR_Nem_3	24	29	PF02991	0.765
LIG_LIR_Nem_3	92	96	PF02991	0.775
LIG_LIR_Nem_3	98	102	PF02991	0.678
LIG_LYPXL_yS_3	227	230	PF13949	0.829
LIG_SH2_CRK	27	31	PF00017	0.759
LIG_SH2_STAP1	446	450	PF00017	0.811
LIG_SH2_STAT3	4	7	PF00017	0.727
LIG_SH2_STAT3	60	63	PF00017	0.779
LIG_SH2_STAT5	229	232	PF00017	0.841
LIG_SH2_STAT5	394	397	PF00017	0.675
LIG_SH2_STAT5	4	7	PF00017	0.727
LIG_SH2_STAT5	60	63	PF00017	0.779
LIG_SH3_3	26	32	PF00018	0.761
LIG_SH3_3	426	432	PF00018	0.811
LIG_SH3_4	31	38	PF00018	0.735
LIG_SUMO_SIM_par_1	156	164	PF11976	0.809
LIG_TRAF2_1	67	70	PF00917	0.718
LIG_WRC_WIRS_1	96	101	PF05994	0.778
MOD_CK1_1	109	115	PF00069	0.812
MOD_CK1_1	206	212	PF00069	0.857
MOD_CK1_1	216	222	PF00069	0.675
MOD_CK1_1	246	252	PF00069	0.861
MOD_CK1_1	260	266	PF00069	0.597
MOD_CK1_1	268	274	PF00069	0.726
MOD_CK1_1	59	65	PF00069	0.775
MOD_CK2_1	172	178	PF00069	0.828
MOD_CK2_1	181	187	PF00069	0.682
MOD_CK2_1	251	257	PF00069	0.855
MOD_CK2_1	318	324	PF00069	0.667
MOD_CK2_1	445	451	PF00069	0.806
MOD_CK2_1	64	70	PF00069	0.730
MOD_Cter_Amidation	292	295	PF01082	0.877
MOD_GlcNHglycan	119	122	PF01048	0.778
MOD_GlcNHglycan	220	223	PF01048	0.834
MOD_GlcNHglycan	250	253	PF01048	0.858
MOD_GlcNHglycan	291	294	PF01048	0.874
MOD_GlcNHglycan	310	313	PF01048	0.453
MOD_GlcNHglycan	418	421	PF01048	0.820
MOD_GlcNHglycan	440	443	PF01048	0.828
MOD_GSK3_1	106	113	PF00069	0.811
MOD_GSK3_1	190	197	PF00069	0.849
MOD_GSK3_1	211	218	PF00069	0.862
MOD_GSK3_1	242	249	PF00069	0.868
MOD_GSK3_1	252	259	PF00069	0.678
MOD_GSK3_1	260	267	PF00069	0.528
MOD_GSK3_1	295	302	PF00069	0.862
MOD_GSK3_1	400	407	PF00069	0.752
MOD_GSK3_1	55	62	PF00069	0.787
MOD_LATS_1	241	247	PF00433	0.868
MOD_N-GLC_1	134	139	PF02516	0.763
MOD_N-GLC_1	261	266	PF02516	0.844
MOD_NEK2_1	134	139	PF00069	0.763
MOD_NEK2_1	14	19	PF00069	0.761
MOD_NEK2_1	21	26	PF00069	0.640
MOD_NEK2_1	215	220	PF00069	0.857
MOD_NEK2_1	404	409	PF00069	0.794
MOD_PIKK_1	299	305	PF00454	0.851
MOD_PIKK_1	59	65	PF00454	0.775
MOD_PK_1	194	200	PF00069	0.859
MOD_PK_1	265	271	PF00069	0.860
MOD_PKA_1	243	249	PF00069	0.868
MOD_PKA_2	242	248	PF00069	0.868
MOD_PKA_2	264	270	PF00069	0.857
MOD_PKA_2	289	295	PF00069	0.876
MOD_PKA_2	377	383	PF00069	0.709
MOD_PKA_2	55	61	PF00069	0.792
MOD_PKA_2	81	87	PF00069	0.736
MOD_Plk_1	203	209	PF00069	0.865
MOD_Plk_2-3	89	95	PF00069	0.762
MOD_Plk_4	324	330	PF00069	0.689
MOD_Plk_4	400	406	PF00069	0.742
MOD_Plk_4	56	62	PF00069	0.789
MOD_Plk_4	89	95	PF00069	0.762
MOD_ProDKin_1	457	463	PF00069	0.822
MOD_SUMO_rev_2	12	17	PF00179	0.748
MOD_SUMO_rev_2	274	282	PF00179	0.863
TRG_AP2beta_CARGO_1	144	153	PF09066	0.745
TRG_DiLeu_BaEn_1	347	352	PF01217	0.661
TRG_DiLeu_LyEn_5	347	352	PF01217	0.661
TRG_ENDOCYTIC_2	227	230	PF00928	0.829
TRG_ENDOCYTIC_2	65	68	PF00928	0.729
TRG_ER_diArg_1	140	143	PF00400	0.747
TRG_ER_diArg_1	236	239	PF00400	0.853
TRG_ER_diArg_1	329	331	PF00400	0.721
TRG_Pf-PMV_PEXEL_1	320	324	PF00026	0.670
TRG_Pf-PMV_PEXEL_1	350	354	PF00026	0.665