Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H5A6_LEIBR

TriTrypDb:

LbrM.08.0400 , LBRM2903_080008900

Length:

968

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H5A6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H5A6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	159	163	PF00656	0.717
CLV_C14_Caspase3-7	165	169	PF00656	0.606
CLV_C14_Caspase3-7	609	613	PF00656	0.852
CLV_C14_Caspase3-7	739	743	PF00656	0.766
CLV_NRD_NRD_1	133	135	PF00675	0.837
CLV_NRD_NRD_1	351	353	PF00675	0.768
CLV_NRD_NRD_1	437	439	PF00675	0.830
CLV_NRD_NRD_1	548	550	PF00675	0.817
CLV_NRD_NRD_1	588	590	PF00675	0.836
CLV_NRD_NRD_1	713	715	PF00675	0.758
CLV_NRD_NRD_1	853	855	PF00675	0.792
CLV_PCSK_FUR_1	131	135	PF00082	0.840
CLV_PCSK_KEX2_1	133	135	PF00082	0.837
CLV_PCSK_KEX2_1	351	353	PF00082	0.768
CLV_PCSK_KEX2_1	368	370	PF00082	0.462
CLV_PCSK_KEX2_1	437	439	PF00082	0.830
CLV_PCSK_KEX2_1	548	550	PF00082	0.817
CLV_PCSK_KEX2_1	855	857	PF00082	0.791
CLV_PCSK_PC1ET2_1	368	370	PF00082	0.759
CLV_PCSK_PC1ET2_1	855	857	PF00082	0.791
CLV_PCSK_SKI1_1	231	235	PF00082	0.693
CLV_PCSK_SKI1_1	538	542	PF00082	0.794
CLV_PCSK_SKI1_1	548	552	PF00082	0.642
CLV_PCSK_SKI1_1	667	671	PF00082	0.752
CLV_PCSK_SKI1_1	714	718	PF00082	0.749
CLV_PCSK_SKI1_1	764	768	PF00082	0.699
CLV_PCSK_SKI1_1	855	859	PF00082	0.785
CLV_Separin_Metazoa	711	715	PF03568	0.761
DEG_APCC_DBOX_1	230	238	PF00400	0.698
DEG_APCC_DBOX_1	351	359	PF00400	0.743
DEG_APCC_DBOX_1	537	545	PF00400	0.797
DEG_Nend_UBRbox_1	1	4	PF02207	0.751
DEG_SPOP_SBC_1	36	40	PF00917	0.755
DOC_CKS1_1	540	545	PF01111	0.792
DOC_CKS1_1	884	889	PF01111	0.828
DOC_CKS1_1	940	945	PF01111	0.780
DOC_CYCLIN_yCln2_LP_2	30	36	PF00134	0.729
DOC_MAPK_gen_1	252	259	PF00069	0.758
DOC_MAPK_gen_1	714	722	PF00069	0.741
DOC_MAPK_MEF2A_6	659	666	PF00069	0.768
DOC_MIT_MIM_1	945	955	PF04212	0.769
DOC_PP1_RVXF_1	647	653	PF00149	0.727
DOC_PP2B_LxvP_1	461	464	PF13499	0.803
DOC_PP2B_LxvP_1	468	471	PF13499	0.724
DOC_PP2B_LxvP_1	604	607	PF13499	0.853
DOC_PP2B_LxvP_1	869	872	PF13499	0.777
DOC_PP4_FxxP_1	554	557	PF00568	0.845
DOC_PP4_FxxP_1	797	800	PF00568	0.758
DOC_USP7_MATH_1	13	17	PF00917	0.673
DOC_USP7_MATH_1	176	180	PF00917	0.812
DOC_USP7_MATH_1	283	287	PF00917	0.844
DOC_USP7_MATH_1	314	318	PF00917	0.711
DOC_USP7_MATH_1	328	332	PF00917	0.619
DOC_USP7_MATH_1	464	468	PF00917	0.826
DOC_USP7_MATH_1	557	561	PF00917	0.854
DOC_USP7_MATH_1	571	575	PF00917	0.589
DOC_USP7_MATH_1	697	701	PF00917	0.839
DOC_USP7_MATH_1	798	802	PF00917	0.728
DOC_USP7_MATH_1	8	12	PF00917	0.767
DOC_USP7_MATH_1	845	849	PF00917	0.833
DOC_USP7_MATH_1	922	926	PF00917	0.858
DOC_WW_Pin1_4	252	257	PF00397	0.769
DOC_WW_Pin1_4	299	304	PF00397	0.807
DOC_WW_Pin1_4	391	396	PF00397	0.858
DOC_WW_Pin1_4	539	544	PF00397	0.789
DOC_WW_Pin1_4	796	801	PF00397	0.761
DOC_WW_Pin1_4	883	888	PF00397	0.818
DOC_WW_Pin1_4	9	14	PF00397	0.776
DOC_WW_Pin1_4	926	931	PF00397	0.846
DOC_WW_Pin1_4	939	944	PF00397	0.565
LIG_14-3-3_CanoR_1	133	142	PF00244	0.793
LIG_14-3-3_CanoR_1	150	155	PF00244	0.341
LIG_14-3-3_CanoR_1	207	215	PF00244	0.843
LIG_14-3-3_CanoR_1	359	364	PF00244	0.722
LIG_14-3-3_CanoR_1	369	374	PF00244	0.594
LIG_14-3-3_CanoR_1	481	488	PF00244	0.859
LIG_14-3-3_CanoR_1	548	557	PF00244	0.828
LIG_14-3-3_CanoR_1	75	80	PF00244	0.773
LIG_14-3-3_CanoR_1	891	901	PF00244	0.835
LIG_Actin_RPEL_3	93	112	PF02755	0.677
LIG_Actin_WH2_2	723	739	PF00022	0.745
LIG_BIR_III_2	842	846	PF00653	0.848
LIG_BRCT_BRCA1_1	800	804	PF00533	0.709
LIG_BRCT_BRCA1_1	829	833	PF00533	0.724
LIG_CSL_BTD_1	33	36	PF09270	0.750
LIG_eIF4E_1	113	119	PF01652	0.654
LIG_eIF4E_1	645	651	PF01652	0.724
LIG_eIF4E_1	822	828	PF01652	0.711
LIG_EVH1_1	468	472	PF00568	0.852
LIG_FHA_1	300	306	PF00498	0.786
LIG_FHA_1	345	351	PF00498	0.794
LIG_FHA_1	48	54	PF00498	0.661
LIG_FHA_1	528	534	PF00498	0.826
LIG_FHA_1	645	651	PF00498	0.724
LIG_FHA_1	652	658	PF00498	0.617
LIG_FHA_1	755	761	PF00498	0.715
LIG_FHA_1	908	914	PF00498	0.824
LIG_FHA_1	957	963	PF00498	0.791
LIG_FHA_2	155	161	PF00498	0.699
LIG_FHA_2	600	606	PF00498	0.853
LIG_FHA_2	687	693	PF00498	0.794
LIG_FHA_2	699	705	PF00498	0.630
LIG_FHA_2	765	771	PF00498	0.700
LIG_FHA_2	893	899	PF00498	0.830
LIG_FHA_2	940	946	PF00498	0.773
LIG_GBD_Chelix_1	905	913	PF00786	0.826
LIG_Integrin_isoDGR_2	399	401	PF01839	0.855
LIG_IRF3_LxIS_1	899	904	PF10401	0.815
LIG_LIR_Apic_2	250	256	PF02991	0.797
LIG_LIR_Apic_2	551	557	PF02991	0.833
LIG_LIR_Gen_1	820	829	PF02991	0.713
LIG_LIR_Gen_1	830	839	PF02991	0.593
LIG_LIR_Nem_3	362	367	PF02991	0.716
LIG_LIR_Nem_3	536	540	PF02991	0.802
LIG_LIR_Nem_3	820	825	PF02991	0.715
LIG_LIR_Nem_3	830	836	PF02991	0.576
LIG_MYND_1	466	470	PF01753	0.842
LIG_NRBOX	26	32	PF00104	0.684
LIG_NRBOX	665	671	PF00104	0.749
LIG_NRBOX	822	828	PF00104	0.711
LIG_NRBOX	951	957	PF00104	0.777
LIG_PCNA_yPIPBox_3	659	670	PF02747	0.763
LIG_PTAP_UEV_1	524	529	PF05743	0.826
LIG_SH2_CRK	113	117	PF00017	0.642
LIG_SH2_CRK	364	368	PF00017	0.717
LIG_SH2_CRK	636	640	PF00017	0.748
LIG_SH2_CRK	645	649	PF00017	0.568
LIG_SH2_SRC	808	811	PF00017	0.714
LIG_SH2_STAP1	636	640	PF00017	0.748
LIG_SH2_STAP1	808	812	PF00017	0.708
LIG_SH2_STAT5	364	367	PF00017	0.710
LIG_SH2_STAT5	774	777	PF00017	0.811
LIG_SH2_STAT5	822	825	PF00017	0.703
LIG_SH3_3	30	36	PF00018	0.729
LIG_SH3_3	300	306	PF00018	0.786
LIG_SH3_3	463	469	PF00018	0.826
LIG_SH3_3	522	528	PF00018	0.832
LIG_SH3_3	537	543	PF00018	0.534
LIG_SH3_3	728	734	PF00018	0.749
LIG_SH3_3	924	930	PF00018	0.853
LIG_SH3_3	937	943	PF00018	0.571
LIG_SUMO_SIM_anti_2	824	830	PF11976	0.706
LIG_SUMO_SIM_par_1	150	157	PF11976	0.653
LIG_SUMO_SIM_par_1	417	423	PF11976	0.754
LIG_SUMO_SIM_par_1	824	830	PF11976	0.706
LIG_TRAF2_1	246	249	PF00917	0.856
LIG_TRAF2_1	269	272	PF00917	0.751
LIG_TRAF2_2	190	195	PF00917	0.859
LIG_TYR_ITIM	111	116	PF00017	0.638
LIG_TYR_ITIM	643	648	PF00017	0.723
LIG_WRC_WIRS_1	451	456	PF05994	0.745
LIG_WRC_WIRS_1	822	827	PF05994	0.711
MOD_CDK_SPK_2	391	396	PF00069	0.858
MOD_CDK_SPK_2	9	14	PF00069	0.776
MOD_CK1_1	153	159	PF00069	0.671
MOD_CK1_1	298	304	PF00069	0.810
MOD_CK1_1	362	368	PF00069	0.720
MOD_CK1_1	38	44	PF00069	0.733
MOD_CK1_1	526	532	PF00069	0.828
MOD_CK1_1	579	585	PF00069	0.812
MOD_CK1_1	596	602	PF00069	0.534
MOD_CK1_1	686	692	PF00069	0.797
MOD_CK1_1	9	15	PF00069	0.770
MOD_CK1_1	926	932	PF00069	0.840
MOD_CK2_1	114	120	PF00069	0.666
MOD_CK2_1	154	160	PF00069	0.685
MOD_CK2_1	176	182	PF00069	0.821
MOD_CK2_1	329	335	PF00069	0.874
MOD_CK2_1	37	43	PF00069	0.743
MOD_CK2_1	425	431	PF00069	0.775
MOD_CK2_1	599	605	PF00069	0.851
MOD_CK2_1	686	692	PF00069	0.797
MOD_CK2_1	764	770	PF00069	0.696
MOD_CK2_1	9	15	PF00069	0.770
MOD_CK2_1	922	928	PF00069	0.859
MOD_CK2_1	939	945	PF00069	0.490
MOD_GlcNHglycan	101	104	PF01048	0.687
MOD_GlcNHglycan	178	181	PF01048	0.821
MOD_GlcNHglycan	241	244	PF01048	0.829
MOD_GlcNHglycan	248	252	PF01048	0.719
MOD_GlcNHglycan	287	290	PF01048	0.845
MOD_GlcNHglycan	326	329	PF01048	0.846
MOD_GlcNHglycan	340	343	PF01048	0.609
MOD_GlcNHglycan	371	374	PF01048	0.770
MOD_GlcNHglycan	407	410	PF01048	0.797
MOD_GlcNHglycan	427	430	PF01048	0.428
MOD_GlcNHglycan	438	441	PF01048	0.629
MOD_GlcNHglycan	482	485	PF01048	0.858
MOD_GlcNHglycan	518	521	PF01048	0.827
MOD_GlcNHglycan	525	528	PF01048	0.706
MOD_GlcNHglycan	551	554	PF01048	0.827
MOD_GlcNHglycan	558	562	PF01048	0.734
MOD_GlcNHglycan	581	584	PF01048	0.808
MOD_GlcNHglycan	599	602	PF01048	0.526
MOD_GlcNHglycan	706	711	PF01048	0.800
MOD_GlcNHglycan	738	741	PF01048	0.762
MOD_GlcNHglycan	8	11	PF01048	0.770
MOD_GlcNHglycan	873	876	PF01048	0.772
MOD_GlcNHglycan	892	895	PF01048	0.512
MOD_GlcNHglycan	930	933	PF01048	0.830
MOD_GSK3_1	150	157	PF00069	0.653
MOD_GSK3_1	176	183	PF00069	0.826
MOD_GSK3_1	279	286	PF00069	0.842
MOD_GSK3_1	291	298	PF00069	0.637
MOD_GSK3_1	324	331	PF00069	0.849
MOD_GSK3_1	359	366	PF00069	0.721
MOD_GSK3_1	37	44	PF00069	0.737
MOD_GSK3_1	436	443	PF00069	0.812
MOD_GSK3_1	523	530	PF00069	0.828
MOD_GSK3_1	567	574	PF00069	0.839
MOD_GSK3_1	593	600	PF00069	0.828
MOD_GSK3_1	651	658	PF00069	0.736
MOD_GSK3_1	682	689	PF00069	0.793
MOD_GSK3_1	786	793	PF00069	0.863
MOD_GSK3_1	817	824	PF00069	0.723
MOD_GSK3_1	9	16	PF00069	0.763
MOD_GSK3_1	907	914	PF00069	0.825
MOD_GSK3_1	922	929	PF00069	0.594
MOD_GSK3_1	95	102	PF00069	0.712
MOD_N-GLC_1	593	598	PF02516	0.825
MOD_NEK2_1	259	264	PF00069	0.677
MOD_NEK2_1	295	300	PF00069	0.840
MOD_NEK2_1	363	368	PF00069	0.719
MOD_NEK2_1	37	42	PF00069	0.754
MOD_NEK2_1	419	424	PF00069	0.763
MOD_NEK2_1	436	441	PF00069	0.524
MOD_NEK2_1	450	455	PF00069	0.499
MOD_NEK2_1	47	52	PF00069	0.489
MOD_NEK2_1	577	582	PF00069	0.817
MOD_NEK2_1	595	600	PF00069	0.512
MOD_NEK2_1	6	11	PF00069	0.761
MOD_NEK2_1	644	649	PF00069	0.726
MOD_NEK2_1	736	741	PF00069	0.763
MOD_NEK2_1	827	832	PF00069	0.721
MOD_NEK2_1	892	897	PF00069	0.842
MOD_NEK2_1	901	906	PF00069	0.666
MOD_NEK2_1	909	914	PF00069	0.528
MOD_NEK2_1	956	961	PF00069	0.782
MOD_NEK2_2	291	296	PF00069	0.851
MOD_PIKK_1	486	492	PF00454	0.855
MOD_PIKK_1	616	622	PF00454	0.876
MOD_PIKK_1	626	632	PF00454	0.665
MOD_PIKK_1	764	770	PF00454	0.696
MOD_PIKK_1	772	778	PF00454	0.657
MOD_PIKK_1	798	804	PF00454	0.721
MOD_PK_1	150	156	PF00069	0.642
MOD_PK_1	75	81	PF00069	0.761
MOD_PKA_1	133	139	PF00069	0.815
MOD_PKA_1	548	554	PF00069	0.823
MOD_PKA_2	133	139	PF00069	0.815
MOD_PKA_2	277	283	PF00069	0.834
MOD_PKA_2	324	330	PF00069	0.847
MOD_PKA_2	41	47	PF00069	0.707
MOD_PKA_2	436	442	PF00069	0.819
MOD_PKA_2	480	486	PF00069	0.860
MOD_PKA_2	548	554	PF00069	0.823
MOD_PKA_2	62	68	PF00069	0.768
MOD_PKA_2	736	742	PF00069	0.768
MOD_PKA_2	74	80	PF00069	0.565
MOD_PKA_2	814	820	PF00069	0.740
MOD_PKA_2	890	896	PF00069	0.847
MOD_PKA_2	899	905	PF00069	0.660
MOD_PKA_2	99	105	PF00069	0.692
MOD_PKB_1	131	139	PF00069	0.822
MOD_Plk_1	142	148	PF00069	0.682
MOD_Plk_1	181	187	PF00069	0.854
MOD_Plk_1	419	425	PF00069	0.757
MOD_Plk_1	47	53	PF00069	0.664
MOD_Plk_1	922	928	PF00069	0.859
MOD_Plk_2-3	923	929	PF00069	0.855
MOD_Plk_4	114	120	PF00069	0.666
MOD_Plk_4	142	148	PF00069	0.682
MOD_Plk_4	150	156	PF00069	0.502
MOD_Plk_4	26	32	PF00069	0.684
MOD_Plk_4	314	320	PF00069	0.722
MOD_Plk_4	359	365	PF00069	0.720
MOD_Plk_4	450	456	PF00069	0.748
MOD_Plk_4	494	500	PF00069	0.834
MOD_Plk_4	529	535	PF00069	0.825
MOD_Plk_4	571	577	PF00069	0.833
MOD_Plk_4	821	827	PF00069	0.714
MOD_ProDKin_1	252	258	PF00069	0.762
MOD_ProDKin_1	299	305	PF00069	0.801
MOD_ProDKin_1	391	397	PF00069	0.857
MOD_ProDKin_1	539	545	PF00069	0.790
MOD_ProDKin_1	796	802	PF00069	0.757
MOD_ProDKin_1	883	889	PF00069	0.821
MOD_ProDKin_1	9	15	PF00069	0.770
MOD_ProDKin_1	926	932	PF00069	0.840
MOD_ProDKin_1	939	945	PF00069	0.560
MOD_SUMO_rev_2	847	857	PF00179	0.807
TRG_DiLeu_BaEn_1	853	858	PF01217	0.789
TRG_DiLeu_BaEn_1	933	938	PF01217	0.820
TRG_DiLeu_BaLyEn_6	253	258	PF01217	0.750
TRG_DiLeu_BaLyEn_6	513	518	PF01217	0.808
TRG_DiLeu_BaLyEn_6	635	640	PF01217	0.756
TRG_DiLeu_BaLyEn_6	646	651	PF01217	0.534
TRG_DiLeu_LyEn_5	853	858	PF01217	0.789
TRG_ENDOCYTIC_2	113	116	PF00928	0.640
TRG_ENDOCYTIC_2	364	367	PF00928	0.710
TRG_ENDOCYTIC_2	636	639	PF00928	0.757
TRG_ENDOCYTIC_2	645	648	PF00928	0.566
TRG_ENDOCYTIC_2	808	811	PF00928	0.714
TRG_ENDOCYTIC_2	822	825	PF00928	0.458
TRG_ER_diArg_1	17	20	PF00400	0.724
TRG_ER_diArg_1	350	352	PF00400	0.777
TRG_ER_diArg_1	436	438	PF00400	0.826
TRG_ER_diArg_1	547	549	PF00400	0.812
TRG_ER_diArg_1	61	64	PF00400	0.719
TRG_ER_diArg_1	854	857	PF00400	0.791
TRG_ER_diArg_1	962	965	PF00400	0.809