LeishMANIAdb
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PHD-type domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
PHD-type domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4H593_LEIBR
TriTrypDb:
LbrM.08.0270 , LBRM2903_080007900 *
Length:
675

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H593
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H593

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 330 334 PF00656 0.838
CLV_NRD_NRD_1 227 229 PF00675 0.848
CLV_NRD_NRD_1 357 359 PF00675 0.754
CLV_NRD_NRD_1 425 427 PF00675 0.863
CLV_NRD_NRD_1 471 473 PF00675 0.881
CLV_NRD_NRD_1 554 556 PF00675 0.755
CLV_NRD_NRD_1 563 565 PF00675 0.559
CLV_NRD_NRD_1 664 666 PF00675 0.679
CLV_NRD_NRD_1 96 98 PF00675 0.868
CLV_PCSK_FUR_1 375 379 PF00082 0.736
CLV_PCSK_FUR_1 561 565 PF00082 0.715
CLV_PCSK_KEX2_1 226 228 PF00082 0.852
CLV_PCSK_KEX2_1 377 379 PF00082 0.734
CLV_PCSK_KEX2_1 386 388 PF00082 0.553
CLV_PCSK_KEX2_1 427 429 PF00082 0.864
CLV_PCSK_KEX2_1 470 472 PF00082 0.884
CLV_PCSK_KEX2_1 49 51 PF00082 0.815
CLV_PCSK_KEX2_1 554 556 PF00082 0.755
CLV_PCSK_KEX2_1 563 565 PF00082 0.559
CLV_PCSK_KEX2_1 577 579 PF00082 0.490
CLV_PCSK_KEX2_1 664 666 PF00082 0.679
CLV_PCSK_KEX2_1 7 9 PF00082 0.858
CLV_PCSK_KEX2_1 98 100 PF00082 0.860
CLV_PCSK_PC1ET2_1 377 379 PF00082 0.734
CLV_PCSK_PC1ET2_1 386 388 PF00082 0.553
CLV_PCSK_PC1ET2_1 427 429 PF00082 0.864
CLV_PCSK_PC1ET2_1 49 51 PF00082 0.815
CLV_PCSK_PC1ET2_1 577 579 PF00082 0.735
CLV_PCSK_PC1ET2_1 7 9 PF00082 0.858
CLV_PCSK_PC1ET2_1 98 100 PF00082 0.860
CLV_PCSK_PC7_1 467 473 PF00082 0.876
CLV_PCSK_SKI1_1 185 189 PF00082 0.816
CLV_PCSK_SKI1_1 288 292 PF00082 0.847
CLV_PCSK_SKI1_1 336 340 PF00082 0.814
CLV_PCSK_SKI1_1 471 475 PF00082 0.884
CLV_PCSK_SKI1_1 486 490 PF00082 0.622
CLV_PCSK_SKI1_1 600 604 PF00082 0.837
DEG_APCC_DBOX_1 142 150 PF00400 0.848
DEG_APCC_DBOX_1 266 274 PF00400 0.846
DEG_APCC_DBOX_1 392 400 PF00400 0.736
DEG_COP1_1 524 533 PF00400 0.858
DEG_SPOP_SBC_1 21 25 PF00917 0.843
DEG_SPOP_SBC_1 433 437 PF00917 0.865
DEG_SPOP_SBC_1 442 446 PF00917 0.703
DOC_CKS1_1 481 486 PF01111 0.866
DOC_CYCLIN_RxL_1 639 650 PF00134 0.674
DOC_CYCLIN_yCln2_LP_2 144 150 PF00134 0.849
DOC_MAPK_gen_1 285 293 PF00069 0.853
DOC_MAPK_gen_1 4 13 PF00069 0.854
DOC_MAPK_gen_1 639 649 PF00069 0.674
DOC_MAPK_gen_1 655 662 PF00069 0.383
DOC_MAPK_MEF2A_6 285 293 PF00069 0.853
DOC_PP2B_LxvP_1 144 147 PF13499 0.836
DOC_PP2B_LxvP_1 256 259 PF13499 0.846
DOC_PP2B_LxvP_1 310 313 PF13499 0.824
DOC_PP4_FxxP_1 111 114 PF00568 0.833
DOC_PP4_FxxP_1 201 204 PF00568 0.812
DOC_PP4_FxxP_1 271 274 PF00568 0.836
DOC_PP4_FxxP_1 280 283 PF00568 0.670
DOC_USP7_MATH_1 21 25 PF00917 0.843
DOC_USP7_MATH_1 232 236 PF00917 0.851
DOC_USP7_MATH_1 252 256 PF00917 0.506
DOC_USP7_MATH_1 301 305 PF00917 0.833
DOC_USP7_MATH_1 31 35 PF00917 0.673
DOC_USP7_MATH_1 313 317 PF00917 0.611
DOC_USP7_MATH_1 325 329 PF00917 0.629
DOC_USP7_MATH_1 392 396 PF00917 0.712
DOC_USP7_MATH_1 433 437 PF00917 0.865
DOC_USP7_MATH_1 473 477 PF00917 0.882
DOC_USP7_MATH_1 493 497 PF00917 0.522
DOC_USP7_MATH_1 550 554 PF00917 0.791
DOC_USP7_MATH_1 621 625 PF00917 0.799
DOC_USP7_UBL2_3 124 128 PF12436 0.831
DOC_USP7_UBL2_3 382 386 PF12436 0.714
DOC_WW_Pin1_4 126 131 PF00397 0.822
DOC_WW_Pin1_4 151 156 PF00397 0.870
DOC_WW_Pin1_4 157 162 PF00397 0.772
DOC_WW_Pin1_4 169 174 PF00397 0.559
DOC_WW_Pin1_4 239 244 PF00397 0.845
DOC_WW_Pin1_4 254 259 PF00397 0.587
DOC_WW_Pin1_4 294 299 PF00397 0.862
DOC_WW_Pin1_4 308 313 PF00397 0.590
DOC_WW_Pin1_4 413 418 PF00397 0.849
DOC_WW_Pin1_4 480 485 PF00397 0.861
DOC_WW_Pin1_4 494 499 PF00397 0.621
DOC_WW_Pin1_4 523 528 PF00397 0.857
DOC_WW_Pin1_4 529 534 PF00397 0.754
DOC_WW_Pin1_4 538 543 PF00397 0.590
DOC_WW_Pin1_4 97 102 PF00397 0.852
LIG_14-3-3_CanoR_1 165 175 PF00244 0.877
LIG_14-3-3_CanoR_1 226 236 PF00244 0.851
LIG_14-3-3_CanoR_1 288 294 PF00244 0.856
LIG_14-3-3_CanoR_1 329 338 PF00244 0.835
LIG_14-3-3_CanoR_1 393 397 PF00244 0.719
LIG_14-3-3_CanoR_1 456 463 PF00244 0.862
LIG_14-3-3_CanoR_1 472 478 PF00244 0.600
LIG_14-3-3_CanoR_1 494 498 PF00244 0.867
LIG_Clathr_ClatBox_1 646 650 PF01394 0.668
LIG_FHA_1 105 111 PF00498 0.857
LIG_FHA_1 158 164 PF00498 0.881
LIG_FHA_1 413 419 PF00498 0.849
LIG_FHA_1 448 454 PF00498 0.865
LIG_FHA_1 53 59 PF00498 0.831
LIG_FHA_1 632 638 PF00498 0.736
LIG_FHA_2 261 267 PF00498 0.848
LIG_FHA_2 98 104 PF00498 0.854
LIG_LIR_Apic_2 269 274 PF02991 0.840
LIG_LIR_Nem_3 215 219 PF02991 0.823
LIG_NRBOX 642 648 PF00104 0.671
LIG_Pex14_2 47 51 PF04695 0.812
LIG_RPA_C_Fungi 567 579 PF08784 0.710
LIG_SH2_CRK 348 352 PF00017 0.691
LIG_SH2_NCK_1 322 326 PF00017 0.845
LIG_SH2_STAP1 322 326 PF00017 0.845
LIG_SH2_STAP1 384 388 PF00017 0.713
LIG_SH2_STAP1 570 574 PF00017 0.701
LIG_SH3_2 92 97 PF14604 0.851
LIG_SH3_3 10 16 PF00018 0.841
LIG_SH3_3 144 150 PF00018 0.849
LIG_SH3_3 172 178 PF00018 0.852
LIG_SH3_3 270 276 PF00018 0.832
LIG_SH3_3 295 301 PF00018 0.849
LIG_SH3_3 414 420 PF00018 0.849
LIG_SH3_3 527 533 PF00018 0.858
LIG_SH3_3 89 95 PF00018 0.851
LIG_SUMO_SIM_anti_2 658 664 PF11976 0.661
LIG_SUMO_SIM_par_1 645 650 PF11976 0.671
LIG_TRAF2_1 177 180 PF00917 0.840
LIG_TRAF2_1 517 520 PF00917 0.762
LIG_UBA3_1 89 98 PF00899 0.856
LIG_WW_2 18 21 PF00397 0.818
LIG_WW_3 1 5 PF00397 0.860
LIG_WW_3 483 487 PF00397 0.867
LIG_WW_3 491 495 PF00397 0.728
LIG_WW_3 536 540 PF00397 0.853
MOD_CDC14_SPxK_1 247 250 PF00782 0.841
MOD_CDK_SPK_2 523 528 PF00069 0.857
MOD_CDK_SPxK_1 126 132 PF00069 0.826
MOD_CDK_SPxK_1 244 250 PF00069 0.843
MOD_CDK_SPxK_1 480 486 PF00069 0.863
MOD_CK1_1 139 145 PF00069 0.833
MOD_CK1_1 157 163 PF00069 0.563
MOD_CK1_1 167 173 PF00069 0.705
MOD_CK1_1 239 245 PF00069 0.842
MOD_CK1_1 30 36 PF00069 0.848
MOD_CK1_1 328 334 PF00069 0.839
MOD_CK1_1 432 438 PF00069 0.863
MOD_CK1_1 441 447 PF00069 0.702
MOD_CK1_1 521 527 PF00069 0.831
MOD_CK1_1 624 630 PF00069 0.790
MOD_CK2_1 512 518 PF00069 0.839
MOD_CK2_1 97 103 PF00069 0.855
MOD_Cter_Amidation 424 427 PF01082 0.862
MOD_Cter_Amidation 5 8 PF01082 0.852
MOD_DYRK1A_RPxSP_1 171 175 PF00069 0.862
MOD_DYRK1A_RPxSP_1 494 498 PF00069 0.867
MOD_GlcNHglycan 111 114 PF01048 0.833
MOD_GlcNHglycan 190 193 PF01048 0.790
MOD_GlcNHglycan 29 32 PF01048 0.852
MOD_GlcNHglycan 33 36 PF01048 0.777
MOD_GlcNHglycan 420 423 PF01048 0.852
MOD_GlcNHglycan 431 434 PF01048 0.665
MOD_GlcNHglycan 439 443 PF01048 0.529
MOD_GlcNHglycan 44 47 PF01048 0.544
MOD_GlcNHglycan 456 459 PF01048 0.568
MOD_GlcNHglycan 475 478 PF01048 0.547
MOD_GlcNHglycan 626 629 PF01048 0.787
MOD_GSK3_1 151 158 PF00069 0.871
MOD_GSK3_1 167 174 PF00069 0.599
MOD_GSK3_1 208 215 PF00069 0.827
MOD_GSK3_1 21 28 PF00069 0.851
MOD_GSK3_1 227 234 PF00069 0.518
MOD_GSK3_1 308 315 PF00069 0.834
MOD_GSK3_1 325 332 PF00069 0.540
MOD_GSK3_1 409 416 PF00069 0.840
MOD_GSK3_1 428 435 PF00069 0.530
MOD_GSK3_1 437 444 PF00069 0.702
MOD_GSK3_1 445 452 PF00069 0.564
MOD_GSK3_1 493 500 PF00069 0.864
MOD_GSK3_1 514 521 PF00069 0.851
MOD_GSK3_1 550 557 PF00069 0.773
MOD_GSK3_1 93 100 PF00069 0.855
MOD_N-GLC_1 334 339 PF02516 0.823
MOD_N-GLC_1 52 57 PF02516 0.830
MOD_NEK2_1 291 296 PF00069 0.873
MOD_OFUCOSY 586 593 PF10250 0.819
MOD_PIKK_1 22 28 PF00454 0.855
MOD_PIKK_1 301 307 PF00454 0.839
MOD_PIKK_1 497 503 PF00454 0.853
MOD_PIKK_1 572 578 PF00454 0.708
MOD_PKA_1 226 232 PF00069 0.849
MOD_PKA_1 471 477 PF00069 0.884
MOD_PKA_1 554 560 PF00069 0.737
MOD_PKA_2 164 170 PF00069 0.890
MOD_PKA_2 226 232 PF00069 0.849
MOD_PKA_2 328 334 PF00069 0.839
MOD_PKA_2 392 398 PF00069 0.719
MOD_PKA_2 433 439 PF00069 0.863
MOD_PKA_2 466 472 PF00069 0.877
MOD_PKA_2 493 499 PF00069 0.864
MOD_PKA_2 554 560 PF00069 0.737
MOD_PKB_1 226 234 PF00069 0.850
MOD_PKB_1 426 434 PF00069 0.862
MOD_Plk_1 139 145 PF00069 0.833
MOD_Plk_1 334 340 PF00069 0.819
MOD_Plk_2-3 633 639 PF00069 0.729
MOD_Plk_4 115 121 PF00069 0.829
MOD_Plk_4 212 218 PF00069 0.828
MOD_ProDKin_1 126 132 PF00069 0.826
MOD_ProDKin_1 151 157 PF00069 0.871
MOD_ProDKin_1 169 175 PF00069 0.552
MOD_ProDKin_1 239 245 PF00069 0.842
MOD_ProDKin_1 254 260 PF00069 0.586
MOD_ProDKin_1 294 300 PF00069 0.861
MOD_ProDKin_1 308 314 PF00069 0.589
MOD_ProDKin_1 413 419 PF00069 0.849
MOD_ProDKin_1 480 486 PF00069 0.863
MOD_ProDKin_1 494 500 PF00069 0.621
MOD_ProDKin_1 523 529 PF00069 0.859
MOD_ProDKin_1 531 537 PF00069 0.711
MOD_ProDKin_1 538 544 PF00069 0.587
MOD_ProDKin_1 97 103 PF00069 0.855
TRG_DiLeu_BaLyEn_6 144 149 PF01217 0.847
TRG_DiLeu_BaLyEn_6 642 647 PF01217 0.673
TRG_ENDOCYTIC_2 348 351 PF00928 0.696
TRG_ER_diArg_1 132 135 PF00400 0.847
TRG_ER_diArg_1 225 228 PF00400 0.850
TRG_ER_diArg_1 470 472 PF00400 0.884
TRG_ER_diArg_1 561 564 PF00400 0.719
TRG_ER_diArg_1 663 665 PF00400 0.675
TRG_NLS_MonoExtC_3 96 101 PF00514 0.859
TRG_NLS_MonoExtN_4 94 101 PF00514 0.852
TRG_Pf-PMV_PEXEL_1 645 650 PF00026 0.671

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS