Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H580_LEIBR

TriTrypDb:

LbrM.08.0130 , LBRM2903_080006700

Length:

1147

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H580

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H580

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1058	1062	PF00656	0.594
CLV_C14_Caspase3-7	314	318	PF00656	0.630
CLV_C14_Caspase3-7	998	1002	PF00656	0.589
CLV_NRD_NRD_1	1012	1014	PF00675	0.813
CLV_NRD_NRD_1	1099	1101	PF00675	0.606
CLV_NRD_NRD_1	1121	1123	PF00675	0.832
CLV_NRD_NRD_1	220	222	PF00675	0.761
CLV_NRD_NRD_1	238	240	PF00675	0.501
CLV_NRD_NRD_1	278	280	PF00675	0.723
CLV_NRD_NRD_1	494	496	PF00675	0.563

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFF5	Leptomonas seymouri	42%	97%
A0A3S7WQ38	Leishmania donovani	66%	100%
A4HTG3	Leishmania infantum	66%	100%
E9AM91	Leishmania mexicana (strain MHOM/GT/2001/U1103)	65%	100%
Q4QIF6	Leishmania major	65%	100%

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