LeishMANIAdb
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Putative phosphoglycerate mutase protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative phosphoglycerate mutase protein
Gene product:
phosphoglycerate mutase protein, putative
Species:
Leishmania braziliensis
UniProt:
A4H573_LEIBR
TriTrypDb:
LbrM.08.0060 , LBRM2903_080005900
Length:
185

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A4H573
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H573

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 11
GO:0004619 phosphoglycerate mutase activity 5 5
GO:0016853 isomerase activity 2 6
GO:0016866 intramolecular transferase activity 3 5
GO:0016868 intramolecular transferase activity, phosphotransferases 4 5
GO:0016787 hydrolase activity 2 1
GO:0016788 hydrolase activity, acting on ester bonds 3 1
GO:0016791 phosphatase activity 5 1
GO:0042578 phosphoric ester hydrolase activity 4 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_KEX2_1 129 131 PF00082 0.180
CLV_PCSK_PC1ET2_1 129 131 PF00082 0.187
DOC_CYCLIN_yCln2_LP_2 172 178 PF00134 0.288
DOC_PP1_RVXF_1 109 116 PF00149 0.288
DOC_PP1_RVXF_1 163 169 PF00149 0.293
DOC_PP2B_LxvP_1 172 175 PF13499 0.288
DOC_WW_Pin1_4 53 58 PF00397 0.245
LIG_BIR_II_1 1 5 PF00653 0.327
LIG_CaM_IQ_9 71 87 PF13499 0.288
LIG_eIF4E_1 101 107 PF01652 0.168
LIG_FHA_1 178 184 PF00498 0.245
LIG_FHA_1 62 68 PF00498 0.277
LIG_LIR_Apic_2 51 57 PF02991 0.168
LIG_LIR_Nem_3 84 90 PF02991 0.250
LIG_PDZ_Class_2 180 185 PF00595 0.264
LIG_SH2_CRK 50 54 PF00017 0.264
LIG_SH2_NCK_1 50 54 PF00017 0.378
LIG_SH2_NCK_1 95 99 PF00017 0.378
LIG_SH2_PTP2 3 6 PF00017 0.168
LIG_SH2_SRC 3 6 PF00017 0.168
LIG_SH2_STAP1 50 54 PF00017 0.288
LIG_SH2_STAT5 114 117 PF00017 0.285
LIG_SH2_STAT5 176 179 PF00017 0.264
LIG_SH2_STAT5 3 6 PF00017 0.341
LIG_SUMO_SIM_anti_2 145 151 PF11976 0.326
LIG_TYR_ITIM 48 53 PF00017 0.288
MOD_CDK_SPxxK_3 53 60 PF00069 0.245
MOD_CK1_1 96 102 PF00069 0.201
MOD_GlcNHglycan 45 48 PF01048 0.288
MOD_GlcNHglycan 90 93 PF01048 0.378
MOD_GSK3_1 31 38 PF00069 0.168
MOD_GSK3_1 48 55 PF00069 0.130
MOD_N-GLC_1 48 53 PF02516 0.348
MOD_NEK2_1 31 36 PF00069 0.232
MOD_PIKK_1 31 37 PF00454 0.216
MOD_Plk_1 48 54 PF00069 0.168
MOD_Plk_4 48 54 PF00069 0.360
MOD_Plk_4 63 69 PF00069 0.135
MOD_ProDKin_1 53 59 PF00069 0.245
MOD_SUMO_for_1 164 167 PF00179 0.255
TRG_DiLeu_BaEn_1 145 150 PF01217 0.378
TRG_ENDOCYTIC_2 3 6 PF00928 0.168
TRG_ENDOCYTIC_2 50 53 PF00928 0.264
TRG_ENDOCYTIC_2 95 98 PF00928 0.378

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IMU2 Leptomonas seymouri 77% 100%
A0A0S4IY74 Bodo saltans 53% 100%
A0A1X0NP76 Trypanosomatidae 59% 100%
A0A3R7MFI2 Trypanosoma rangeli 57% 100%
A0A3S5H625 Leishmania donovani 85% 100%
A1AJW4 Escherichia coli O1:K1 / APEC 27% 86%
A1JJB8 Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081) 27% 86%
A1TC01 Mycolicibacterium vanbaalenii (strain DSM 7251 / JCM 13017 / BCRC 16820 / KCTC 9966 / NRRL B-24157 / PYR-1) 31% 82%
A1UTM4 Bartonella bacilliformis (strain ATCC 35685 / NCTC 12138 / KC583) 29% 90%
A2RI67 Lactococcus lactis subsp. cremoris (strain MG1363) 26% 79%
A4HTF6 Leishmania infantum 86% 100%
A4TQH5 Yersinia pestis (strain Pestoides F) 27% 86%
A4W6B3 Enterobacter sp. (strain 638) 29% 86%
A5E8K1 Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182) 27% 89%
A6TI09 Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578) 29% 86%
A6WYJ2 Brucella anthropi (strain ATCC 49188 / DSM 6882 / CCUG 24695 / JCM 21032 / LMG 3331 / NBRC 15819 / NCTC 12168 / Alc 37) 27% 90%
A7FMF8 Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) 27% 86%
A7HZ35 Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966) 26% 88%
A7MIJ0 Cronobacter sakazakii (strain ATCC BAA-894) 27% 86%
A7ZVT7 Escherichia coli O139:H28 (strain E24377A / ETEC) 27% 86%
A8A8C4 Escherichia coli O9:H4 (strain HS) 27% 86%
A8ALW1 Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696) 27% 86%
A8IGZ9 Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571) 28% 90%
A9MR94 Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980) 27% 86%
A9N7F5 Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) 27% 86%
A9R032 Yersinia pestis bv. Antiqua (strain Angola) 27% 86%
A9W5P5 Methylorubrum extorquens (strain PA1) 29% 87%
B0UBD4 Methylobacterium sp. (strain 4-46) 29% 89%
B1IS24 Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks) 27% 86%
B1JL20 Yersinia pseudotuberculosis serotype O:3 (strain YPIII) 27% 86%
B1LEK2 Escherichia coli (strain SMS-3-5 / SECEC) 27% 86%
B1M6A7 Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 / 0-1) 26% 87%
B1XFK5 Escherichia coli (strain K12 / DH10B) 27% 86%
B1ZA86 Methylorubrum populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001) 29% 87%
B2K3K5 Yersinia pseudotuberculosis serotype IB (strain PB1/+) 27% 86%
B2TZS8 Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) 27% 86%
B4EY52 Proteus mirabilis (strain HI4320) 28% 86%
B4T4I9 Salmonella newport (strain SL254) 27% 86%
B4TH18 Salmonella heidelberg (strain SL476) 27% 86%
B4TU55 Salmonella schwarzengrund (strain CVM19633) 27% 86%
B5BAL1 Salmonella paratyphi A (strain AKU_12601) 28% 86%
B5F543 Salmonella agona (strain SL483) 27% 86%
B5FTD9 Salmonella dublin (strain CT_02021853) 27% 86%
B5R3B7 Salmonella enteritidis PT4 (strain P125109) 27% 86%
B5R9W3 Salmonella gallinarum (strain 287/91 / NCTC 13346) 27% 86%
B5Y264 Klebsiella pneumoniae (strain 342) 29% 86%
B5Z4S7 Escherichia coli O157:H7 (strain EC4115 / EHEC) 27% 86%
B6I6P3 Escherichia coli (strain SE11) 27% 86%
B7KNX9 Methylorubrum extorquens (strain CM4 / NCIMB 13688) 29% 87%
B7LEP1 Escherichia coli (strain 55989 / EAEC) 27% 86%
B7LNT7 Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73) 29% 86%
B7LXV9 Escherichia coli O8 (strain IAI1) 27% 86%
B7MNK4 Escherichia coli O45:K1 (strain S88 / ExPEC) 27% 86%
B7MTE3 Escherichia coli O81 (strain ED1a) 27% 86%
B7NH70 Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) 27% 86%
B7NW76 Escherichia coli O7:K1 (strain IAI39 / ExPEC) 27% 86%
B8EML2 Methylocella silvestris (strain DSM 15510 / CIP 108128 / LMG 27833 / NCIMB 13906 / BL2) 29% 90%
B9JYQ2 Agrobacterium vitis (strain S4 / ATCC BAA-846) 27% 88%
C0Q8F5 Salmonella paratyphi C (strain RKS4594) 27% 86%
C3MBY8 Sinorhizobium fredii (strain NBRC 101917 / NGR234) 28% 88%
C4ZT77 Escherichia coli (strain K12 / MC4100 / BW2952) 27% 86%
C5BJ25 Teredinibacter turnerae (strain ATCC 39867 / T7901) 26% 75%
C9ZPN2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 56% 100%
D3DFG8 Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6) 28% 88%
D3DFP8 Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6) 32% 91%
E9AM84 Leishmania mexicana (strain MHOM/GT/2001/U1103) 85% 100%
F4KI56 Arabidopsis thaliana 32% 78%
O07617 Bacillus subtilis (strain 168) 28% 96%
P0A7A2 Escherichia coli (strain K12) 27% 86%
P0A7A3 Escherichia coli O157:H7 27% 86%
P0A7A4 Shigella flexneri 27% 86%
Q031Y3 Lactococcus lactis subsp. cremoris (strain SK11) 26% 79%
Q0SX17 Shigella flexneri serotype 5b (strain 8401) 27% 86%
Q0T8R6 Escherichia coli O6:K15:H31 (strain 536 / UPEC) 27% 86%
Q11CB5 Chelativorans sp. (strain BNC1) 30% 90%
Q1C0L5 Yersinia pestis bv. Antiqua (strain Antiqua) 27% 86%
Q1CMX2 Yersinia pestis bv. Antiqua (strain Nepal516) 27% 86%
Q1QRT7 Nitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14) 27% 89%
Q1R246 Escherichia coli (strain UTI89 / UPEC) 27% 86%
Q21CH5 Rhodopseudomonas palustris (strain BisB18) 27% 89%
Q31SU3 Shigella boydii serotype 4 (strain Sb227) 27% 86%
Q327K0 Shigella dysenteriae serotype 1 (strain Sd197) 27% 86%
Q3SW71 Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255) 27% 89%
Q3YTZ9 Shigella sonnei (strain Ss046) 27% 86%
Q4JSW4 Corynebacterium jeikeium (strain K411) 28% 73%
Q4QIG3 Leishmania major 83% 100%
Q57G26 Salmonella choleraesuis (strain SC-B67) 27% 86%
Q5PK44 Salmonella paratyphi A (strain ATCC 9150 / SARB42) 27% 86%
Q66EU3 Yersinia pseudotuberculosis serotype I (strain IP32953) 27% 86%
Q7N900 Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01) 27% 86%
Q89WK1 Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110) 28% 89%
Q8FA40 Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) 27% 86%
Q8KL44 Rhizobium etli (strain CFN 42 / ATCC 51251) 27% 89%
Q8Z0T4 Salmonella typhi 27% 86%
Q8ZIP0 Yersinia pestis 27% 86%
Q8ZJU8 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 27% 86%
Q92T25 Rhizobium meliloti (strain 1021) 27% 88%
Q98DM0 Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) 29% 90%
Q9CIM0 Lactococcus lactis subsp. lactis (strain IL1403) 26% 79%
Q9SCS3 Arabidopsis thaliana 33% 80%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS