ATP-dependent DNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNA repair and recombination helicase protein PIF7, putative

Species:

Leishmania braziliensis

UniProt:

A4H550_LEIBR

TriTrypDb:

LbrM.07.1070 , LBRM2903_070019700 , LBRM2903_070019800

Length:

1329

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	6
GO:0110165	cellular anatomical entity	1	7
GO:0005657	replication fork	2	1
GO:0005739	mitochondrion	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1

Expansion

Sequence features

A4H550

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term	Name	Level	Count
GO:0000723	telomere maintenance	5	7
GO:0006139	nucleobase-containing compound metabolic process	3	7
GO:0006259	DNA metabolic process	4	7
GO:0006281	DNA repair	5	7
GO:0006310	DNA recombination	5	7
GO:0006725	cellular aromatic compound metabolic process	3	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0006950	response to stress	2	7
GO:0006974	DNA damage response	4	7
GO:0006996	organelle organization	4	7
GO:0008152	metabolic process	1	7
GO:0009987	cellular process	1	7
GO:0016043	cellular component organization	3	7
GO:0032200	telomere organization	6	7
GO:0033554	cellular response to stress	3	7
GO:0034641	cellular nitrogen compound metabolic process	3	7
GO:0043170	macromolecule metabolic process	3	7
GO:0044237	cellular metabolic process	2	7
GO:0044238	primary metabolic process	2	7
GO:0044260	obsolete cellular macromolecule metabolic process	3	7
GO:0046483	heterocycle metabolic process	3	7
GO:0050896	response to stimulus	1	7
GO:0051276	chromosome organization	5	7
GO:0051716	cellular response to stimulus	2	7
GO:0071704	organic substance metabolic process	2	7
GO:0071840	cellular component organization or biogenesis	2	7
GO:0090304	nucleic acid metabolic process	4	7
GO:1901360	organic cyclic compound metabolic process	3	7
GO:0006260	DNA replication	5	1
GO:0032392	DNA geometric change	7	1
GO:0032508	DNA duplex unwinding	8	1
GO:0071103	DNA conformation change	6	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	7
GO:0003678	DNA helicase activity	3	7
GO:0003824	catalytic activity	1	7
GO:0004386	helicase activity	2	7
GO:0005488	binding	1	7
GO:0005524	ATP binding	5	7
GO:0008094	ATP-dependent activity, acting on DNA	2	7
GO:0016462	pyrophosphatase activity	5	7
GO:0016787	hydrolase activity	2	7
GO:0016817	hydrolase activity, acting on acid anhydrides	3	7
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	7
GO:0016887	ATP hydrolysis activity	7	7
GO:0017076	purine nucleotide binding	4	7
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	7
GO:0030554	adenyl nucleotide binding	5	7
GO:0032553	ribonucleotide binding	3	7
GO:0032555	purine ribonucleotide binding	4	7
GO:0032559	adenyl ribonucleotide binding	5	7
GO:0035639	purine ribonucleoside triphosphate binding	4	7
GO:0036094	small molecule binding	2	7
GO:0043167	ion binding	2	7
GO:0043168	anion binding	3	7
GO:0097159	organic cyclic compound binding	2	7
GO:0097367	carbohydrate derivative binding	2	7
GO:0140097	catalytic activity, acting on DNA	3	7
GO:0140640	catalytic activity, acting on a nucleic acid	2	7
GO:0140657	ATP-dependent activity	1	7
GO:1901265	nucleoside phosphate binding	3	7
GO:1901363	heterocyclic compound binding	2	7
GO:0000287	magnesium ion binding	5	1
GO:0043169	cation binding	3	1
GO:0046872	metal ion binding	4	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1032	1036	PF00656	0.689
CLV_C14_Caspase3-7	1174	1178	PF00656	0.334
CLV_C14_Caspase3-7	1322	1326	PF00656	0.447
CLV_C14_Caspase3-7	310	314	PF00656	0.553
CLV_C14_Caspase3-7	436	440	PF00656	0.438
CLV_C14_Caspase3-7	512	516	PF00656	0.290
CLV_NRD_NRD_1	1000	1002	PF00675	0.364
CLV_NRD_NRD_1	1052	1054	PF00675	0.542
CLV_NRD_NRD_1	1222	1224	PF00675	0.424
CLV_NRD_NRD_1	1233	1235	PF00675	0.285
CLV_NRD_NRD_1	30	32	PF00675	0.492
CLV_NRD_NRD_1	513	515	PF00675	0.411
CLV_NRD_NRD_1	68	70	PF00675	0.453
CLV_NRD_NRD_1	702	704	PF00675	0.446
CLV_NRD_NRD_1	776	778	PF00675	0.318
CLV_NRD_NRD_1	889	891	PF00675	0.518
CLV_NRD_NRD_1	926	928	PF00675	0.587
CLV_NRD_NRD_1	978	980	PF00675	0.751
CLV_NRD_NRD_1	992	994	PF00675	0.499
CLV_PCSK_FUR_1	511	515	PF00082	0.513
CLV_PCSK_FUR_1	887	891	PF00082	0.641
CLV_PCSK_FUR_1	924	928	PF00082	0.482
CLV_PCSK_KEX2_1	1000	1002	PF00082	0.362
CLV_PCSK_KEX2_1	1051	1053	PF00082	0.551
CLV_PCSK_KEX2_1	1222	1224	PF00082	0.424
CLV_PCSK_KEX2_1	1233	1235	PF00082	0.285
CLV_PCSK_KEX2_1	30	32	PF00082	0.492
CLV_PCSK_KEX2_1	513	515	PF00082	0.411
CLV_PCSK_KEX2_1	605	607	PF00082	0.567
CLV_PCSK_KEX2_1	68	70	PF00082	0.453
CLV_PCSK_KEX2_1	776	778	PF00082	0.482
CLV_PCSK_KEX2_1	889	891	PF00082	0.518
CLV_PCSK_KEX2_1	926	928	PF00082	0.545
CLV_PCSK_KEX2_1	978	980	PF00082	0.753
CLV_PCSK_KEX2_1	992	994	PF00082	0.509
CLV_PCSK_PC1ET2_1	605	607	PF00082	0.567
CLV_PCSK_PC7_1	601	607	PF00082	0.680
CLV_PCSK_PC7_1	885	891	PF00082	0.631
CLV_PCSK_SKI1_1	1052	1056	PF00082	0.512
CLV_PCSK_SKI1_1	1222	1226	PF00082	0.410
CLV_PCSK_SKI1_1	1268	1272	PF00082	0.558
CLV_PCSK_SKI1_1	1274	1278	PF00082	0.459
CLV_PCSK_SKI1_1	366	370	PF00082	0.465
CLV_PCSK_SKI1_1	68	72	PF00082	0.460
CLV_PCSK_SKI1_1	688	692	PF00082	0.578
CLV_PCSK_SKI1_1	707	711	PF00082	0.473
CLV_PCSK_SKI1_1	795	799	PF00082	0.620
CLV_PCSK_SKI1_1	912	916	PF00082	0.374
DEG_COP1_1	219	227	PF00400	0.417
DEG_Nend_UBRbox_2	1	3	PF02207	0.505
DEG_SPOP_SBC_1	230	234	PF00917	0.458
DEG_SPOP_SBC_1	307	311	PF00917	0.549
DEG_SPOP_SBC_1	349	353	PF00917	0.532
DEG_SPOP_SBC_1	401	405	PF00917	0.358
DEG_SPOP_SBC_1	626	630	PF00917	0.419
DEG_SPOP_SBC_1	946	950	PF00917	0.670
DOC_CKS1_1	537	542	PF01111	0.416
DOC_CYCLIN_RxL_1	541	550	PF00134	0.270
DOC_CYCLIN_RxL_1	874	884	PF00134	0.542
DOC_MAPK_DCC_7	30	40	PF00069	0.452
DOC_MAPK_DCC_7	764	773	PF00069	0.476
DOC_MAPK_gen_1	1196	1205	PF00069	0.500
DOC_MAPK_gen_1	1222	1230	PF00069	0.317
DOC_MAPK_gen_1	30	38	PF00069	0.509
DOC_MAPK_gen_1	453	463	PF00069	0.411
DOC_MAPK_gen_1	703	711	PF00069	0.453
DOC_MAPK_MEF2A_6	1051	1060	PF00069	0.381
DOC_MAPK_MEF2A_6	31	40	PF00069	0.513
DOC_MAPK_MEF2A_6	529	536	PF00069	0.411
DOC_MAPK_MEF2A_6	764	773	PF00069	0.472
DOC_MAPK_MEF2A_6	805	813	PF00069	0.431
DOC_PP1_RVXF_1	542	549	PF00149	0.439
DOC_PP1_RVXF_1	574	580	PF00149	0.619
DOC_PP1_RVXF_1	883	889	PF00149	0.514
DOC_PP2B_LxvP_1	287	290	PF13499	0.431
DOC_PP2B_LxvP_1	504	507	PF13499	0.411
DOC_USP7_MATH_1	103	107	PF00917	0.624
DOC_USP7_MATH_1	1030	1034	PF00917	0.574
DOC_USP7_MATH_1	1097	1101	PF00917	0.316
DOC_USP7_MATH_1	1146	1150	PF00917	0.634
DOC_USP7_MATH_1	1217	1221	PF00917	0.380
DOC_USP7_MATH_1	290	294	PF00917	0.433
DOC_USP7_MATH_1	360	364	PF00917	0.390
DOC_USP7_MATH_1	401	405	PF00917	0.463
DOC_USP7_MATH_1	432	436	PF00917	0.342
DOC_USP7_MATH_1	52	56	PF00917	0.506
DOC_USP7_MATH_1	608	612	PF00917	0.587
DOC_USP7_MATH_1	914	918	PF00917	0.395
DOC_USP7_MATH_1	946	950	PF00917	0.670
DOC_USP7_MATH_1	953	957	PF00917	0.575
DOC_WW_Pin1_4	1052	1057	PF00397	0.497
DOC_WW_Pin1_4	1135	1140	PF00397	0.557
DOC_WW_Pin1_4	131	136	PF00397	0.604
DOC_WW_Pin1_4	14	19	PF00397	0.581
DOC_WW_Pin1_4	176	181	PF00397	0.640
DOC_WW_Pin1_4	246	251	PF00397	0.563
DOC_WW_Pin1_4	46	51	PF00397	0.580
DOC_WW_Pin1_4	514	519	PF00397	0.513
DOC_WW_Pin1_4	536	541	PF00397	0.416
DOC_WW_Pin1_4	906	911	PF00397	0.594
DOC_WW_Pin1_4	942	947	PF00397	0.627
LIG_14-3-3_CanoR_1	104	108	PF00244	0.452
LIG_14-3-3_CanoR_1	1131	1140	PF00244	0.490
LIG_14-3-3_CanoR_1	12	18	PF00244	0.513
LIG_14-3-3_CanoR_1	1222	1231	PF00244	0.467
LIG_14-3-3_CanoR_1	269	277	PF00244	0.479
LIG_14-3-3_CanoR_1	317	321	PF00244	0.745
LIG_14-3-3_CanoR_1	434	442	PF00244	0.261
LIG_14-3-3_CanoR_1	450	456	PF00244	0.507
LIG_14-3-3_CanoR_1	617	626	PF00244	0.582
LIG_14-3-3_CanoR_1	764	768	PF00244	0.471
LIG_14-3-3_CanoR_1	849	856	PF00244	0.459
LIG_14-3-3_CanoR_1	865	873	PF00244	0.482
LIG_14-3-3_CanoR_1	887	897	PF00244	0.606
LIG_BRCT_BRCA1_1	1099	1103	PF00533	0.337
LIG_BRCT_BRCA1_1	402	406	PF00533	0.411
LIG_BRCT_BRCA1_1	499	503	PF00533	0.411
LIG_BRCT_BRCA1_1	516	520	PF00533	0.411
LIG_BRCT_BRCA1_1	537	541	PF00533	0.411
LIG_BRCT_BRCA1_1	87	91	PF00533	0.418
LIG_FHA_1	1042	1048	PF00498	0.630
LIG_FHA_1	1053	1059	PF00498	0.526
LIG_FHA_1	1209	1215	PF00498	0.563
LIG_FHA_1	1223	1229	PF00498	0.468
LIG_FHA_1	1278	1284	PF00498	0.469
LIG_FHA_1	1293	1299	PF00498	0.402
LIG_FHA_1	143	149	PF00498	0.638
LIG_FHA_1	259	265	PF00498	0.552
LIG_FHA_1	266	272	PF00498	0.545
LIG_FHA_1	408	414	PF00498	0.438
LIG_FHA_1	531	537	PF00498	0.261
LIG_FHA_1	572	578	PF00498	0.510
LIG_FHA_1	584	590	PF00498	0.551
LIG_FHA_1	723	729	PF00498	0.500
LIG_FHA_1	930	936	PF00498	0.522
LIG_FHA_2	1093	1099	PF00498	0.349
LIG_FHA_2	1253	1259	PF00498	0.489
LIG_FHA_2	154	160	PF00498	0.739
LIG_FHA_2	238	244	PF00498	0.619
LIG_FHA_2	370	376	PF00498	0.424
LIG_FHA_2	632	638	PF00498	0.628
LIG_FHA_2	657	663	PF00498	0.515
LIG_FHA_2	673	679	PF00498	0.265
LIG_FHA_2	725	731	PF00498	0.560
LIG_FHA_2	781	787	PF00498	0.437
LIG_FHA_2	826	832	PF00498	0.589
LIG_HP1_1	193	197	PF01393	0.479
LIG_LIR_Apic_2	32	37	PF02991	0.457
LIG_LIR_Gen_1	1100	1108	PF02991	0.461
LIG_LIR_Gen_1	500	509	PF02991	0.411
LIG_LIR_Gen_1	651	661	PF02991	0.507
LIG_LIR_Gen_1	729	739	PF02991	0.438
LIG_LIR_Gen_1	831	838	PF02991	0.355
LIG_LIR_Gen_1	852	863	PF02991	0.332
LIG_LIR_LC3C_4	784	789	PF02991	0.637
LIG_LIR_Nem_3	1100	1106	PF02991	0.463
LIG_LIR_Nem_3	1220	1224	PF02991	0.482
LIG_LIR_Nem_3	1278	1282	PF02991	0.433
LIG_LIR_Nem_3	470	476	PF02991	0.364
LIG_LIR_Nem_3	490	495	PF02991	0.183
LIG_LIR_Nem_3	500	506	PF02991	0.411
LIG_LIR_Nem_3	524	530	PF02991	0.410
LIG_LIR_Nem_3	554	560	PF02991	0.477
LIG_LIR_Nem_3	647	653	PF02991	0.488
LIG_LIR_Nem_3	678	684	PF02991	0.522
LIG_LIR_Nem_3	729	734	PF02991	0.388
LIG_LIR_Nem_3	831	837	PF02991	0.428
LIG_LIR_Nem_3	843	847	PF02991	0.567
LIG_LIR_Nem_3	852	858	PF02991	0.421
LIG_MYND_1	33	37	PF01753	0.460
LIG_PCNA_PIPBox_1	1060	1069	PF02747	0.370
LIG_PDZ_Class_2	1324	1329	PF00595	0.459
LIG_Pex14_2	1103	1107	PF04695	0.520
LIG_Pex14_2	295	299	PF04695	0.458
LIG_Pex14_2	834	838	PF04695	0.425
LIG_SH2_CRK	288	292	PF00017	0.418
LIG_SH2_CRK	653	657	PF00017	0.506
LIG_SH2_CRK	671	675	PF00017	0.570
LIG_SH2_CRK	876	880	PF00017	0.477
LIG_SH2_CRK	913	917	PF00017	0.536
LIG_SH2_NCK_1	1173	1177	PF00017	0.336
LIG_SH2_NCK_1	913	917	PF00017	0.383
LIG_SH2_PTP2	844	847	PF00017	0.466
LIG_SH2_PTP2	855	858	PF00017	0.477
LIG_SH2_STAP1	1279	1283	PF00017	0.429
LIG_SH2_STAP1	1303	1307	PF00017	0.415
LIG_SH2_STAP1	367	371	PF00017	0.411
LIG_SH2_STAP1	815	819	PF00017	0.434
LIG_SH2_STAT3	670	673	PF00017	0.622
LIG_SH2_STAT5	1185	1188	PF00017	0.304
LIG_SH2_STAT5	1279	1282	PF00017	0.494
LIG_SH2_STAT5	1316	1319	PF00017	0.535
LIG_SH2_STAT5	34	37	PF00017	0.464
LIG_SH2_STAT5	479	482	PF00017	0.411
LIG_SH2_STAT5	653	656	PF00017	0.504
LIG_SH2_STAT5	739	742	PF00017	0.513
LIG_SH2_STAT5	844	847	PF00017	0.466
LIG_SH2_STAT5	855	858	PF00017	0.477
LIG_SH3_1	485	491	PF00018	0.411
LIG_SH3_3	1091	1097	PF00018	0.583
LIG_SH3_3	1140	1146	PF00018	0.579
LIG_SH3_3	1173	1179	PF00018	0.333
LIG_SH3_3	118	124	PF00018	0.579
LIG_SH3_3	1202	1208	PF00018	0.524
LIG_SH3_3	137	143	PF00018	0.534
LIG_SH3_3	187	193	PF00018	0.606
LIG_SH3_3	19	25	PF00018	0.537
LIG_SH3_3	222	228	PF00018	0.524
LIG_SH3_3	239	245	PF00018	0.632
LIG_SH3_3	249	255	PF00018	0.649
LIG_SH3_3	342	348	PF00018	0.729
LIG_SH3_3	485	491	PF00018	0.411
LIG_SH3_3	785	791	PF00018	0.510
LIG_SH3_3	804	810	PF00018	0.434
LIG_SUMO_SIM_anti_2	1189	1195	PF11976	0.451
LIG_SUMO_SIM_anti_2	563	570	PF11976	0.472
LIG_SUMO_SIM_anti_2	634	640	PF11976	0.660
LIG_SUMO_SIM_par_1	1310	1315	PF11976	0.269
LIG_SUMO_SIM_par_1	459	465	PF11976	0.513
LIG_TRAF2_1	322	325	PF00917	0.486
LIG_TRAF2_1	675	678	PF00917	0.340
LIG_TRAF2_1	898	901	PF00917	0.509
LIG_UBA3_1	1057	1065	PF00899	0.376
LIG_UBA3_1	329	338	PF00899	0.520
LIG_WRC_WIRS_1	423	428	PF05994	0.411
LIG_WRC_WIRS_1	731	736	PF05994	0.439
MOD_CDK_SPK_2	131	136	PF00069	0.707
MOD_CDK_SPxK_1	536	542	PF00069	0.416
MOD_CDK_SPxK_1	906	912	PF00069	0.357
MOD_CK1_1	10	16	PF00069	0.550
MOD_CK1_1	1129	1135	PF00069	0.419
MOD_CK1_1	1138	1144	PF00069	0.477
MOD_CK1_1	1319	1325	PF00069	0.289
MOD_CK1_1	169	175	PF00069	0.653
MOD_CK1_1	183	189	PF00069	0.665
MOD_CK1_1	198	204	PF00069	0.615
MOD_CK1_1	219	225	PF00069	0.537
MOD_CK1_1	226	232	PF00069	0.605
MOD_CK1_1	246	252	PF00069	0.447
MOD_CK1_1	256	262	PF00069	0.551
MOD_CK1_1	293	299	PF00069	0.566
MOD_CK1_1	319	325	PF00069	0.584
MOD_CK1_1	419	425	PF00069	0.382
MOD_CK1_1	44	50	PF00069	0.571
MOD_CK1_1	440	446	PF00069	0.459
MOD_CK1_1	570	576	PF00069	0.509
MOD_CK1_1	627	633	PF00069	0.570
MOD_CK1_1	63	69	PF00069	0.519
MOD_CK1_1	724	730	PF00069	0.463
MOD_CK1_1	77	83	PF00069	0.467
MOD_CK1_1	840	846	PF00069	0.565
MOD_CK1_1	848	854	PF00069	0.458
MOD_CK1_1	85	91	PF00069	0.499
MOD_CK1_1	942	948	PF00069	0.657
MOD_CK1_1	951	957	PF00069	0.564
MOD_CK2_1	1092	1098	PF00069	0.354
MOD_CK2_1	1129	1135	PF00069	0.522
MOD_CK2_1	1252	1258	PF00069	0.454
MOD_CK2_1	153	159	PF00069	0.617
MOD_CK2_1	175	181	PF00069	0.488
MOD_CK2_1	197	203	PF00069	0.690
MOD_CK2_1	269	275	PF00069	0.661
MOD_CK2_1	319	325	PF00069	0.570
MOD_CK2_1	369	375	PF00069	0.261
MOD_CK2_1	464	470	PF00069	0.411
MOD_CK2_1	631	637	PF00069	0.664
MOD_CK2_1	656	662	PF00069	0.514
MOD_CK2_1	672	678	PF00069	0.269
MOD_CK2_1	780	786	PF00069	0.401
MOD_Cter_Amidation	976	979	PF01082	0.552
MOD_GlcNHglycan	1098	1102	PF01048	0.476
MOD_GlcNHglycan	1167	1170	PF01048	0.331
MOD_GlcNHglycan	1321	1324	PF01048	0.529
MOD_GlcNHglycan	233	236	PF01048	0.652
MOD_GlcNHglycan	255	258	PF01048	0.616
MOD_GlcNHglycan	377	380	PF01048	0.261
MOD_GlcNHglycan	418	421	PF01048	0.411
MOD_GlcNHglycan	499	502	PF01048	0.411
MOD_GlcNHglycan	58	61	PF01048	0.556
MOD_GlcNHglycan	592	595	PF01048	0.522
MOD_GlcNHglycan	609	613	PF01048	0.590
MOD_GlcNHglycan	63	66	PF01048	0.490
MOD_GlcNHglycan	75	79	PF01048	0.669
MOD_GlcNHglycan	839	842	PF01048	0.561
MOD_GlcNHglycan	85	88	PF01048	0.498
MOD_GlcNHglycan	94	97	PF01048	0.341
MOD_GSK3_1	1092	1099	PF00069	0.353
MOD_GSK3_1	1122	1129	PF00069	0.483
MOD_GSK3_1	1131	1138	PF00069	0.532
MOD_GSK3_1	142	149	PF00069	0.610
MOD_GSK3_1	169	176	PF00069	0.621
MOD_GSK3_1	216	223	PF00069	0.497
MOD_GSK3_1	226	233	PF00069	0.584
MOD_GSK3_1	256	263	PF00069	0.549
MOD_GSK3_1	265	272	PF00069	0.666
MOD_GSK3_1	293	300	PF00069	0.555
MOD_GSK3_1	316	323	PF00069	0.621
MOD_GSK3_1	375	382	PF00069	0.513
MOD_GSK3_1	401	408	PF00069	0.369
MOD_GSK3_1	41	48	PF00069	0.655
MOD_GSK3_1	418	425	PF00069	0.392
MOD_GSK3_1	433	440	PF00069	0.299
MOD_GSK3_1	52	59	PF00069	0.530
MOD_GSK3_1	567	574	PF00069	0.516
MOD_GSK3_1	6	13	PF00069	0.569
MOD_GSK3_1	621	628	PF00069	0.543
MOD_GSK3_1	722	729	PF00069	0.471
MOD_GSK3_1	77	84	PF00069	0.546
MOD_GSK3_1	815	822	PF00069	0.310
MOD_GSK3_1	85	92	PF00069	0.523
MOD_GSK3_1	864	871	PF00069	0.401
MOD_GSK3_1	914	921	PF00069	0.557
MOD_GSK3_1	929	936	PF00069	0.690
MOD_GSK3_1	937	944	PF00069	0.615
MOD_GSK3_1	947	954	PF00069	0.495
MOD_GSK3_1	98	105	PF00069	0.397
MOD_N-GLC_1	1030	1035	PF02516	0.628
MOD_N-GLC_1	1041	1046	PF02516	0.694
MOD_N-GLC_1	13	18	PF02516	0.514
MOD_N-GLC_1	416	421	PF02516	0.411
MOD_N-GLC_1	432	437	PF02516	0.411
MOD_N-GLC_1	721	726	PF02516	0.481
MOD_N-GLC_1	868	873	PF02516	0.394
MOD_NEK2_1	1041	1046	PF00069	0.748
MOD_NEK2_1	109	114	PF00069	0.439
MOD_NEK2_1	1181	1186	PF00069	0.554
MOD_NEK2_1	1277	1282	PF00069	0.439
MOD_NEK2_1	1283	1288	PF00069	0.422
MOD_NEK2_1	171	176	PF00069	0.650
MOD_NEK2_1	196	201	PF00069	0.647
MOD_NEK2_1	218	223	PF00069	0.649
MOD_NEK2_1	231	236	PF00069	0.531
MOD_NEK2_1	369	374	PF00069	0.261
MOD_NEK2_1	392	397	PF00069	0.513
MOD_NEK2_1	416	421	PF00069	0.381
MOD_NEK2_1	441	446	PF00069	0.272
MOD_NEK2_1	56	61	PF00069	0.580
MOD_NEK2_1	631	636	PF00069	0.602
MOD_NEK2_1	656	661	PF00069	0.514
MOD_NEK2_1	825	830	PF00069	0.480
MOD_NEK2_1	91	96	PF00069	0.430
MOD_NEK2_1	934	939	PF00069	0.635
MOD_NEK2_2	618	623	PF00069	0.578
MOD_NEK2_2	815	820	PF00069	0.434
MOD_PIKK_1	142	148	PF00454	0.435
MOD_PIKK_1	7	13	PF00454	0.572
MOD_PIKK_1	77	83	PF00454	0.501
MOD_PIKK_1	819	825	PF00454	0.472
MOD_PK_1	1172	1178	PF00069	0.335
MOD_PK_1	1310	1316	PF00069	0.387
MOD_PK_1	547	553	PF00069	0.295
MOD_PKA_1	1222	1228	PF00069	0.321
MOD_PKA_1	513	519	PF00069	0.513
MOD_PKA_1	68	74	PF00069	0.468
MOD_PKA_2	103	109	PF00069	0.481
MOD_PKA_2	112	118	PF00069	0.518
MOD_PKA_2	1222	1228	PF00069	0.472
MOD_PKA_2	1244	1250	PF00069	0.408
MOD_PKA_2	1319	1325	PF00069	0.289
MOD_PKA_2	316	322	PF00069	0.786
MOD_PKA_2	433	439	PF00069	0.513
MOD_PKA_2	513	519	PF00069	0.513
MOD_PKA_2	56	62	PF00069	0.496
MOD_PKA_2	656	662	PF00069	0.472
MOD_PKA_2	68	74	PF00069	0.433
MOD_PKA_2	763	769	PF00069	0.483
MOD_PKA_2	848	854	PF00069	0.413
MOD_PKA_2	864	870	PF00069	0.481
MOD_PKA_2	888	894	PF00069	0.611
MOD_PKA_2	929	935	PF00069	0.732
MOD_PKB_1	267	275	PF00069	0.494
MOD_PKB_1	511	519	PF00069	0.513
MOD_Plk_1	1041	1047	PF00069	0.737
MOD_Plk_1	124	130	PF00069	0.474
MOD_Plk_1	1277	1283	PF00069	0.284
MOD_Plk_1	464	470	PF00069	0.411
MOD_Plk_1	868	874	PF00069	0.395
MOD_Plk_2-3	464	470	PF00069	0.411
MOD_Plk_4	103	109	PF00069	0.531
MOD_Plk_4	1119	1125	PF00069	0.584
MOD_Plk_4	1181	1187	PF00069	0.373
MOD_Plk_4	1277	1283	PF00069	0.492
MOD_Plk_4	1294	1300	PF00069	0.399
MOD_Plk_4	226	232	PF00069	0.642
MOD_Plk_4	402	408	PF00069	0.411
MOD_Plk_4	437	443	PF00069	0.450
MOD_Plk_4	464	470	PF00069	0.411
MOD_Plk_4	523	529	PF00069	0.290
MOD_Plk_4	595	601	PF00069	0.424
MOD_Plk_4	651	657	PF00069	0.448
MOD_Plk_4	763	769	PF00069	0.483
MOD_Plk_4	840	846	PF00069	0.551
MOD_Plk_4	86	92	PF00069	0.500
MOD_ProDKin_1	1052	1058	PF00069	0.494
MOD_ProDKin_1	1135	1141	PF00069	0.559
MOD_ProDKin_1	131	137	PF00069	0.604
MOD_ProDKin_1	14	20	PF00069	0.585
MOD_ProDKin_1	176	182	PF00069	0.646
MOD_ProDKin_1	246	252	PF00069	0.562
MOD_ProDKin_1	46	52	PF00069	0.581
MOD_ProDKin_1	514	520	PF00069	0.513
MOD_ProDKin_1	536	542	PF00069	0.416
MOD_ProDKin_1	906	912	PF00069	0.595
MOD_ProDKin_1	942	948	PF00069	0.630
MOD_SUMO_for_1	1171	1174	PF00179	0.339
MOD_SUMO_for_1	973	976	PF00179	0.779
MOD_SUMO_rev_2	790	797	PF00179	0.585
TRG_DiLeu_BaEn_1	213	218	PF01217	0.604
TRG_DiLeu_BaEn_2	574	580	PF01217	0.619
TRG_DiLeu_BaLyEn_6	1053	1058	PF01217	0.527
TRG_DiLeu_BaLyEn_6	1176	1181	PF01217	0.464
TRG_DiLeu_BaLyEn_6	807	812	PF01217	0.531
TRG_DiLeu_BaLyEn_6	94	99	PF01217	0.383
TRG_DiLeu_LyEn_5	1226	1231	PF01217	0.307
TRG_DiLeu_LyEn_5	325	330	PF01217	0.504
TRG_ENDOCYTIC_2	1161	1164	PF00928	0.430
TRG_ENDOCYTIC_2	1173	1176	PF00928	0.330
TRG_ENDOCYTIC_2	288	291	PF00928	0.572
TRG_ENDOCYTIC_2	653	656	PF00928	0.504
TRG_ENDOCYTIC_2	671	674	PF00928	0.592
TRG_ENDOCYTIC_2	681	684	PF00928	0.463
TRG_ENDOCYTIC_2	844	847	PF00928	0.466
TRG_ENDOCYTIC_2	855	858	PF00928	0.477
TRG_ENDOCYTIC_2	876	879	PF00928	0.480
TRG_ER_diArg_1	1000	1002	PF00400	0.532
TRG_ER_diArg_1	1050	1053	PF00400	0.556
TRG_ER_diArg_1	1221	1223	PF00400	0.510
TRG_ER_diArg_1	484	487	PF00400	0.411
TRG_ER_diArg_1	541	544	PF00400	0.411
TRG_ER_diArg_1	68	70	PF00400	0.453
TRG_ER_diArg_1	775	777	PF00400	0.322
TRG_ER_diArg_1	885	888	PF00400	0.518
TRG_ER_diArg_1	924	927	PF00400	0.482
TRG_Pf-PMV_PEXEL_1	1274	1278	PF00026	0.456
TRG_Pf-PMV_PEXEL_1	269	273	PF00026	0.728
TRG_Pf-PMV_PEXEL_1	459	464	PF00026	0.411
TRG_Pf-PMV_PEXEL_1	68	72	PF00026	0.460
TRG_Pf-PMV_PEXEL_1	785	790	PF00026	0.637
TRG_Pf-PMV_PEXEL_1	964	968	PF00026	0.522

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3C2	Leptomonas seymouri	54%	100%
A0A3S7WQ25	Leishmania donovani	71%	100%
A4HTC6	Leishmania infantum	71%	100%
E9ALB9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	70%	100%
Q4QII5	Leishmania major	70%	100%