RNA binding protein-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

RNA binding protein-like protein

Species:

Leishmania braziliensis

UniProt:

A4H548_LEIBR

TriTrypDb:

LbrM.07.1050 , LBRM2903_070019500

Length:

458

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	1
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4H548

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H548

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	201	205	PF00656	0.715
CLV_C14_Caspase3-7	241	245	PF00656	0.851
CLV_C14_Caspase3-7	249	253	PF00656	0.708
CLV_C14_Caspase3-7	267	271	PF00656	0.666
CLV_C14_Caspase3-7	284	288	PF00656	0.800
CLV_NRD_NRD_1	1	3	PF00675	0.563
CLV_NRD_NRD_1	456	458	PF00675	0.576
CLV_NRD_NRD_1	8	10	PF00675	0.509
CLV_PCSK_KEX2_1	455	457	PF00082	0.573
CLV_PCSK_KEX2_1	8	10	PF00082	0.524
CLV_PCSK_SKI1_1	148	152	PF00082	0.275
CLV_PCSK_SKI1_1	29	33	PF00082	0.538
DEG_Nend_UBRbox_1	1	4	PF02207	0.558
DOC_CYCLIN_yClb3_PxF_3	79	85	PF00134	0.433
DOC_CYCLIN_yCln2_LP_2	151	157	PF00134	0.243
DOC_MAPK_DCC_7	9	19	PF00069	0.516
DOC_MAPK_MEF2A_6	148	157	PF00069	0.238
DOC_MAPK_MEF2A_6	207	214	PF00069	0.533
DOC_MAPK_NFAT4_5	207	215	PF00069	0.533
DOC_PP1_RVXF_1	44	50	PF00149	0.494
DOC_PP2B_LxvP_1	105	108	PF13499	0.527
DOC_PP2B_LxvP_1	151	154	PF13499	0.527
DOC_USP7_MATH_1	140	144	PF00917	0.516
DOC_USP7_MATH_1	169	173	PF00917	0.527
DOC_USP7_MATH_1	246	250	PF00917	0.559
DOC_USP7_MATH_1	350	354	PF00917	0.622
DOC_WW_Pin1_4	358	363	PF00397	0.782
DOC_WW_Pin1_4	367	372	PF00397	0.752
DOC_WW_Pin1_4	376	381	PF00397	0.699
DOC_WW_Pin1_4	385	390	PF00397	0.786
DOC_WW_Pin1_4	394	399	PF00397	0.732
DOC_WW_Pin1_4	403	408	PF00397	0.585
DOC_WW_Pin1_4	412	417	PF00397	0.572
DOC_WW_Pin1_4	421	426	PF00397	0.653
DOC_WW_Pin1_4	439	444	PF00397	0.636
DOC_WW_Pin1_4	95	100	PF00397	0.527
LIG_14-3-3_CanoR_1	2	10	PF00244	0.535
LIG_14-3-3_CanoR_1	46	50	PF00244	0.491
LIG_BRCT_BRCA1_1	27	31	PF00533	0.531
LIG_BRCT_BRCA1_1	54	58	PF00533	0.475
LIG_DLG_GKlike_1	13	21	PF00625	0.514
LIG_EVH1_2	81	85	PF00568	0.440
LIG_FHA_1	127	133	PF00498	0.527
LIG_FHA_1	60	66	PF00498	0.468
LIG_LIR_Gen_1	48	56	PF02991	0.480
LIG_LIR_Gen_1	91	99	PF02991	0.527
LIG_LIR_Nem_3	48	52	PF02991	0.484
LIG_LIR_Nem_3	91	95	PF02991	0.373
LIG_Pex14_2	49	53	PF04695	0.484
LIG_PTAP_UEV_1	303	308	PF05743	0.847
LIG_REV1ctd_RIR_1	165	174	PF16727	0.527
LIG_SH2_NCK_1	139	143	PF00017	0.527
LIG_SH2_STAT5	131	134	PF00017	0.527
LIG_SH3_3	301	307	PF00018	0.847
LIG_SH3_3	76	82	PF00018	0.430
LIG_TRAF2_1	271	274	PF00917	0.551
LIG_TRAF2_1	329	332	PF00917	0.687
MOD_CDK_SPxxK_3	358	365	PF00069	0.734
MOD_CDK_SPxxK_3	367	374	PF00069	0.631
MOD_CDK_SPxxK_3	376	383	PF00069	0.673
MOD_CDK_SPxxK_3	385	392	PF00069	0.812
MOD_CDK_SPxxK_3	394	401	PF00069	0.753
MOD_CDK_SPxxK_3	403	410	PF00069	0.588
MOD_CDK_SPxxK_3	412	419	PF00069	0.571
MOD_CDK_SPxxK_3	421	428	PF00069	0.655
MOD_CDK_SPxxK_3	439	446	PF00069	0.638
MOD_CK1_1	116	122	PF00069	0.488
MOD_CK1_1	143	149	PF00069	0.527
MOD_CK1_1	20	26	PF00069	0.503
MOD_CK1_1	358	364	PF00069	0.718
MOD_CK1_1	376	382	PF00069	0.852
MOD_CK1_1	394	400	PF00069	0.602
MOD_CK1_1	412	418	PF00069	0.634
MOD_CK1_1	98	104	PF00069	0.272
MOD_CK2_1	200	206	PF00069	0.764
MOD_CK2_1	232	238	PF00069	0.571
MOD_CK2_1	268	274	PF00069	0.653
MOD_CK2_1	306	312	PF00069	0.842
MOD_Cter_Amidation	453	456	PF01082	0.574
MOD_GlcNHglycan	132	135	PF01048	0.484
MOD_GlcNHglycan	171	174	PF01048	0.388
MOD_GlcNHglycan	244	247	PF01048	0.846
MOD_GlcNHglycan	248	252	PF01048	0.777
MOD_GlcNHglycan	358	361	PF01048	0.850
MOD_GlcNHglycan	375	378	PF01048	0.705
MOD_GlcNHglycan	393	396	PF01048	0.703
MOD_GlcNHglycan	411	414	PF01048	0.631
MOD_GlcNHglycan	429	432	PF01048	0.827
MOD_GlcNHglycan	447	450	PF01048	0.735
MOD_GSK3_1	126	133	PF00069	0.367
MOD_GSK3_1	215	222	PF00069	0.583
MOD_GSK3_1	242	249	PF00069	0.684
MOD_GSK3_1	252	259	PF00069	0.780
MOD_GSK3_1	30	37	PF00069	0.539
MOD_GSK3_1	302	309	PF00069	0.845
MOD_GSK3_1	363	370	PF00069	0.860
MOD_GSK3_1	381	388	PF00069	0.697
MOD_GSK3_1	399	406	PF00069	0.650
MOD_GSK3_1	417	424	PF00069	0.613
MOD_GSK3_1	435	442	PF00069	0.602
MOD_GSK3_1	9	16	PF00069	0.516
MOD_GSK3_1	93	100	PF00069	0.243
MOD_LATS_1	7	13	PF00433	0.519
MOD_N-GLC_1	195	200	PF02516	0.588
MOD_NEK2_1	1	6	PF00069	0.549
MOD_NEK2_1	113	118	PF00069	0.369
MOD_NEK2_1	17	22	PF00069	0.475
MOD_NEK2_1	32	37	PF00069	0.506
MOD_NEK2_1	51	56	PF00069	0.435
MOD_NEK2_1	58	63	PF00069	0.450
MOD_NEK2_1	68	73	PF00069	0.442
MOD_NEK2_1	84	89	PF00069	0.404
MOD_NEK2_2	126	131	PF00069	0.527
MOD_NEK2_2	171	176	PF00069	0.369
MOD_NEK2_2	45	50	PF00069	0.492
MOD_PIKK_1	143	149	PF00454	0.394
MOD_PIKK_1	17	23	PF00454	0.509
MOD_PKA_1	8	14	PF00069	0.520
MOD_PKA_2	1	7	PF00069	0.544
MOD_PKA_2	23	29	PF00069	0.478
MOD_PKA_2	232	238	PF00069	0.579
MOD_PKA_2	355	361	PF00069	0.861
MOD_PKA_2	373	379	PF00069	0.710
MOD_PKA_2	391	397	PF00069	0.786
MOD_PKA_2	409	415	PF00069	0.633
MOD_PKA_2	427	433	PF00069	0.553
MOD_PKA_2	445	451	PF00069	0.697
MOD_PKA_2	45	51	PF00069	0.491
MOD_PKA_2	8	14	PF00069	0.504
MOD_Plk_2-3	195	201	PF00069	0.753
MOD_Plk_2-3	232	238	PF00069	0.571
MOD_Plk_2-3	252	258	PF00069	0.846
MOD_Plk_2-3	268	274	PF00069	0.579
MOD_Plk_2-3	321	327	PF00069	0.825
MOD_Plk_4	113	119	PF00069	0.454
MOD_Plk_4	126	132	PF00069	0.286
MOD_Plk_4	84	90	PF00069	0.429
MOD_ProDKin_1	358	364	PF00069	0.783
MOD_ProDKin_1	367	373	PF00069	0.754
MOD_ProDKin_1	376	382	PF00069	0.700
MOD_ProDKin_1	385	391	PF00069	0.789
MOD_ProDKin_1	394	400	PF00069	0.731
MOD_ProDKin_1	403	409	PF00069	0.586
MOD_ProDKin_1	412	418	PF00069	0.570
MOD_ProDKin_1	421	427	PF00069	0.656
MOD_ProDKin_1	439	445	PF00069	0.637
MOD_ProDKin_1	95	101	PF00069	0.527
MOD_SUMO_rev_2	133	138	PF00179	0.527
TRG_DiLeu_BaEn_1	238	243	PF01217	0.562
TRG_DiLeu_BaEn_4	322	328	PF01217	0.560
TRG_ER_diArg_1	455	457	PF00400	0.635
TRG_ER_diArg_1	8	10	PF00400	0.524

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WQ00	Leishmania donovani	64%	100%
A4HTC4	Leishmania infantum	63%	100%
E9ALB7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	67%	100%
Q4QII7	Leishmania major	68%	99%