LeishMANIAdb
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Putative nucleolar RNA-binding protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Putative nucleolar RNA-binding protein
Gene product:
nucleolar RNA-binding protein, putative
Species:
Leishmania braziliensis
UniProt:
A4H547_LEIBR
TriTrypDb:
LbrM.07.1040 , LBRM2903_070019400 *
Length:
327

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 5
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 2
NetGPI no yes: 0, no: 2
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H547
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H547

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_KEX2_1 59 61 PF00082 0.299
CLV_PCSK_PC1ET2_1 59 61 PF00082 0.299
CLV_PCSK_SKI1_1 13 17 PF00082 0.549
CLV_PCSK_SKI1_1 49 53 PF00082 0.277
DEG_Nend_UBRbox_2 1 3 PF02207 0.515
DOC_CYCLIN_yCln2_LP_2 30 36 PF00134 0.299
DOC_MAPK_MEF2A_6 26 34 PF00069 0.299
DOC_PP2B_LxvP_1 30 33 PF13499 0.299
DOC_USP7_MATH_1 107 111 PF00917 0.599
DOC_USP7_MATH_1 148 152 PF00917 0.636
LIG_14-3-3_CanoR_1 26 34 PF00244 0.277
LIG_Actin_WH2_2 12 28 PF00022 0.299
LIG_FHA_1 65 71 PF00498 0.324
LIG_FHA_1 88 94 PF00498 0.354
LIG_LIR_Apic_2 90 95 PF02991 0.277
LIG_LIR_Nem_3 2 7 PF02991 0.277
LIG_Pex14_2 42 46 PF04695 0.299
LIG_SH2_PTP2 92 95 PF00017 0.416
LIG_SH2_STAT5 92 95 PF00017 0.513
LIG_TRAF2_1 110 113 PF00917 0.689
LIG_WRC_WIRS_1 43 48 PF05994 0.299
MOD_CK2_1 107 113 PF00069 0.632
MOD_CK2_1 127 133 PF00069 0.530
MOD_CK2_1 148 154 PF00069 0.632
MOD_GlcNHglycan 109 112 PF01048 0.593
MOD_GlcNHglycan 142 145 PF01048 0.633
MOD_GlcNHglycan 295 298 PF01048 0.620
MOD_GlcNHglycan 79 82 PF01048 0.345
MOD_GSK3_1 127 134 PF00069 0.628
MOD_GSK3_1 38 45 PF00069 0.380
MOD_NEK2_1 25 30 PF00069 0.375
MOD_NEK2_1 69 74 PF00069 0.433
MOD_PIKK_1 25 31 PF00454 0.375
MOD_PKA_2 25 31 PF00069 0.277
MOD_Plk_1 75 81 PF00069 0.386
MOD_Plk_2-3 127 133 PF00069 0.629
MOD_Plk_4 38 44 PF00069 0.341
MOD_SUMO_rev_2 41 51 PF00179 0.299
TRG_ER_diArg_1 324 327 PF00400 0.582

Homologs

Protein Taxonomy Sequence identity Coverage
C9ZUJ5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 89%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS