Radial spoke protein 9

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H541_LEIBR

TriTrypDb:

LbrM.07.0980 , LBRM2903_070018700

Length:

335

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

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Cellular components
Term	Name	Level	Count
GO:0001534	radial spoke	2	2
GO:0005930	axoneme	2	1
GO:0032991	protein-containing complex	1	2
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

A4H541

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H541

Function

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Biological processes
Term	Name	Level	Count
GO:0000226	microtubule cytoskeleton organization	3	1
GO:0001578	microtubule bundle formation	4	1
GO:0003341	cilium movement	4	3
GO:0006996	organelle organization	4	3
GO:0007010	cytoskeleton organization	5	1
GO:0007017	microtubule-based process	2	3
GO:0007018	microtubule-based movement	3	3
GO:0009987	cellular process	1	3
GO:0016043	cellular component organization	3	3
GO:0022607	cellular component assembly	4	3

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Could not find GO molecular_function term for this entry.

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	163	167	PF00656	0.498
CLV_NRD_NRD_1	173	175	PF00675	0.629
CLV_PCSK_KEX2_1	175	177	PF00082	0.520
CLV_PCSK_PC1ET2_1	175	177	PF00082	0.520
CLV_PCSK_SKI1_1	176	180	PF00082	0.655
CLV_PCSK_SKI1_1	207	211	PF00082	0.498
CLV_PCSK_SKI1_1	292	296	PF00082	0.439
DEG_SCF_FBW7_1	125	131	PF00400	0.414
DOC_CKS1_1	125	130	PF01111	0.555
DOC_MAPK_gen_1	174	185	PF00069	0.444

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8E1	Leptomonas seymouri	26%	100%
A0A0N1IL99	Leptomonas seymouri	71%	98%
A0A0S4J8G1	Bodo saltans	40%	100%
A0A1X0NQ76	Trypanosomatidae	48%	100%
A0A1X0P3V0	Trypanosomatidae	26%	100%
A0A3Q8IKD9	Leishmania donovani	24%	100%
A0A3R7MSU5	Trypanosoma rangeli	48%	99%
A0A3S7WQ16	Leishmania donovani	86%	100%
A0A422P0B0	Trypanosoma rangeli	26%	100%
A4HLW1	Leishmania braziliensis	22%	100%

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