LeishMANIAdb
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Calcium-transporting ATPase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Calcium-transporting ATPase
Gene product:
vacuolar-type Ca2+-ATPase, putative
Species:
Leishmania braziliensis
UniProt:
A4H514_LEIBR
TriTrypDb:
LbrM.07.0700 , LBRM2903_070013900 * , LBRM2903_330017000 *
Length:
1126

Annotations

LeishMANIAdb annotations

Homologous to other eukaryotic P-type Ca2+ ATPases.. For some reason, this group has heavily expanded in Kinetoplastida.. Localization: Endosomal (by homology) / ER (by homology)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 18
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 19
NetGPI no yes: 0, no: 19
Cellular components
Term Name Level Count
GO:0016020 membrane 2 20
GO:0110165 cellular anatomical entity 1 20
GO:0005886 plasma membrane 3 3
GO:0043226 organelle 2 3
GO:0043227 membrane-bounded organelle 3 3
GO:0043229 intracellular organelle 3 3
GO:0043231 intracellular membrane-bounded organelle 4 3

Expansion

Sequence features

A4H514
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H514

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 20
GO:0003824 catalytic activity 1 20
GO:0005215 transporter activity 1 16
GO:0005388 P-type calcium transporter activity 4 16
GO:0005488 binding 1 20
GO:0005524 ATP binding 5 20
GO:0008324 monoatomic cation transmembrane transporter activity 4 16
GO:0015075 monoatomic ion transmembrane transporter activity 3 16
GO:0015085 calcium ion transmembrane transporter activity 6 16
GO:0015318 inorganic molecular entity transmembrane transporter activity 3 16
GO:0015399 primary active transmembrane transporter activity 4 16
GO:0015662 P-type ion transporter activity 4 16
GO:0016462 pyrophosphatase activity 5 20
GO:0016787 hydrolase activity 2 20
GO:0016817 hydrolase activity, acting on acid anhydrides 3 20
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4 20
GO:0016887 ATP hydrolysis activity 7 20
GO:0017076 purine nucleotide binding 4 20
GO:0017111 ribonucleoside triphosphate phosphatase activity 6 20
GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 3 16
GO:0022804 active transmembrane transporter activity 3 16
GO:0022853 active monoatomic ion transmembrane transporter activity 4 16
GO:0022857 transmembrane transporter activity 2 16
GO:0022890 inorganic cation transmembrane transporter activity 4 16
GO:0030554 adenyl nucleotide binding 5 20
GO:0032553 ribonucleotide binding 3 20
GO:0032555 purine ribonucleotide binding 4 20
GO:0032559 adenyl ribonucleotide binding 5 20
GO:0035639 purine ribonucleoside triphosphate binding 4 20
GO:0036094 small molecule binding 2 20
GO:0042626 ATPase-coupled transmembrane transporter activity 2 16
GO:0043167 ion binding 2 20
GO:0043168 anion binding 3 20
GO:0046873 metal ion transmembrane transporter activity 5 16
GO:0097159 organic cyclic compound binding 2 20
GO:0097367 carbohydrate derivative binding 2 20
GO:0140358 P-type transmembrane transporter activity 3 16
GO:0140657 ATP-dependent activity 1 16
GO:1901265 nucleoside phosphate binding 3 20
GO:1901363 heterocyclic compound binding 2 20

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 527 531 PF00656 0.457
CLV_C14_Caspase3-7 661 665 PF00656 0.558
CLV_MEL_PAP_1 45 51 PF00089 0.322
CLV_NRD_NRD_1 114 116 PF00675 0.254
CLV_NRD_NRD_1 197 199 PF00675 0.301
CLV_NRD_NRD_1 218 220 PF00675 0.356
CLV_NRD_NRD_1 36 38 PF00675 0.456
CLV_NRD_NRD_1 411 413 PF00675 0.383
CLV_NRD_NRD_1 473 475 PF00675 0.383
CLV_NRD_NRD_1 542 544 PF00675 0.259
CLV_NRD_NRD_1 559 561 PF00675 0.277
CLV_NRD_NRD_1 819 821 PF00675 0.290
CLV_NRD_NRD_1 887 889 PF00675 0.281
CLV_NRD_NRD_1 895 897 PF00675 0.280
CLV_NRD_NRD_1 951 953 PF00675 0.266
CLV_PCSK_FUR_1 1028 1032 PF00082 0.404
CLV_PCSK_FUR_1 216 220 PF00082 0.276
CLV_PCSK_KEX2_1 1030 1032 PF00082 0.375
CLV_PCSK_KEX2_1 1072 1074 PF00082 0.464
CLV_PCSK_KEX2_1 114 116 PF00082 0.265
CLV_PCSK_KEX2_1 218 220 PF00082 0.335
CLV_PCSK_KEX2_1 411 413 PF00082 0.383
CLV_PCSK_KEX2_1 453 455 PF00082 0.465
CLV_PCSK_KEX2_1 473 475 PF00082 0.353
CLV_PCSK_KEX2_1 51 53 PF00082 0.483
CLV_PCSK_KEX2_1 561 563 PF00082 0.292
CLV_PCSK_KEX2_1 882 884 PF00082 0.325
CLV_PCSK_KEX2_1 895 897 PF00082 0.265
CLV_PCSK_KEX2_1 926 928 PF00082 0.435
CLV_PCSK_PC1ET2_1 1030 1032 PF00082 0.344
CLV_PCSK_PC1ET2_1 1072 1074 PF00082 0.326
CLV_PCSK_PC1ET2_1 453 455 PF00082 0.399
CLV_PCSK_PC1ET2_1 51 53 PF00082 0.516
CLV_PCSK_PC1ET2_1 561 563 PF00082 0.294
CLV_PCSK_PC1ET2_1 882 884 PF00082 0.257
CLV_PCSK_PC1ET2_1 926 928 PF00082 0.435
CLV_PCSK_SKI1_1 1048 1052 PF00082 0.385
CLV_PCSK_SKI1_1 1104 1108 PF00082 0.527
CLV_PCSK_SKI1_1 1116 1120 PF00082 0.311
CLV_PCSK_SKI1_1 114 118 PF00082 0.280
CLV_PCSK_SKI1_1 120 124 PF00082 0.263
CLV_PCSK_SKI1_1 145 149 PF00082 0.335
CLV_PCSK_SKI1_1 549 553 PF00082 0.336
CLV_PCSK_SKI1_1 724 728 PF00082 0.351
CLV_PCSK_SKI1_1 746 750 PF00082 0.291
CLV_PCSK_SKI1_1 820 824 PF00082 0.276
CLV_PCSK_SKI1_1 968 972 PF00082 0.238
CLV_Separin_Metazoa 353 357 PF03568 0.418
DEG_APCC_DBOX_1 967 975 PF00400 0.409
DEG_SCF_FBW7_2 318 325 PF00400 0.482
DEG_SPOP_SBC_1 481 485 PF00917 0.501
DEG_SPOP_SBC_1 488 492 PF00917 0.589
DOC_CYCLIN_RxL_1 818 828 PF00134 0.490
DOC_CYCLIN_yCln2_LP_2 458 464 PF00134 0.584
DOC_MAPK_DCC_7 454 464 PF00069 0.581
DOC_MAPK_gen_1 1070 1079 PF00069 0.541
DOC_MAPK_gen_1 473 481 PF00069 0.426
DOC_MAPK_gen_1 820 827 PF00069 0.486
DOC_MAPK_gen_1 895 903 PF00069 0.516
DOC_MAPK_gen_1 926 937 PF00069 0.323
DOC_MAPK_gen_1 952 960 PF00069 0.501
DOC_MAPK_gen_1 966 974 PF00069 0.405
DOC_MAPK_JIP1_4 968 974 PF00069 0.345
DOC_MAPK_MEF2A_6 746 753 PF00069 0.498
DOC_MAPK_MEF2A_6 820 829 PF00069 0.469
DOC_MAPK_MEF2A_6 895 903 PF00069 0.417
DOC_MAPK_MEF2A_6 966 973 PF00069 0.427
DOC_MAPK_NFAT4_5 746 754 PF00069 0.498
DOC_MAPK_NFAT4_5 820 828 PF00069 0.469
DOC_PP1_RVXF_1 805 812 PF00149 0.488
DOC_PP1_RVXF_1 994 1000 PF00149 0.204
DOC_PP2B_LxvP_1 159 162 PF13499 0.438
DOC_PP2B_LxvP_1 243 246 PF13499 0.466
DOC_USP7_MATH_1 1061 1065 PF00917 0.558
DOC_USP7_MATH_1 12 16 PF00917 0.556
DOC_USP7_MATH_1 151 155 PF00917 0.323
DOC_USP7_MATH_1 362 366 PF00917 0.537
DOC_USP7_MATH_1 480 484 PF00917 0.592
DOC_USP7_MATH_1 555 559 PF00917 0.458
DOC_USP7_MATH_1 789 793 PF00917 0.529
DOC_USP7_MATH_1 891 895 PF00917 0.493
DOC_WW_Pin1_4 237 242 PF00397 0.518
DOC_WW_Pin1_4 274 279 PF00397 0.376
DOC_WW_Pin1_4 318 323 PF00397 0.456
DOC_WW_Pin1_4 846 851 PF00397 0.331
LIG_14-3-3_CanoR_1 1075 1080 PF00244 0.685
LIG_14-3-3_CanoR_1 145 150 PF00244 0.261
LIG_14-3-3_CanoR_1 468 473 PF00244 0.543
LIG_14-3-3_CanoR_1 474 481 PF00244 0.430
LIG_14-3-3_CanoR_1 509 518 PF00244 0.400
LIG_14-3-3_CanoR_1 52 57 PF00244 0.674
LIG_14-3-3_CanoR_1 996 1006 PF00244 0.204
LIG_Actin_WH2_2 1107 1122 PF00022 0.492
LIG_Actin_WH2_2 985 1000 PF00022 0.476
LIG_AP2alpha_1 369 373 PF02296 0.482
LIG_BIR_II_1 1 5 PF00653 0.609
LIG_BIR_III_4 717 721 PF00653 0.625
LIG_BRCT_BRCA1_1 966 970 PF00533 0.483
LIG_CNOT1_NIM_1 366 375 PF04054 0.424
LIG_DLG_GKlike_1 468 475 PF00625 0.536
LIG_EVH1_2 127 131 PF00568 0.476
LIG_FHA_1 1003 1009 PF00498 0.390
LIG_FHA_1 101 107 PF00498 0.365
LIG_FHA_1 1010 1016 PF00498 0.389
LIG_FHA_1 1088 1094 PF00498 0.675
LIG_FHA_1 1105 1111 PF00498 0.594
LIG_FHA_1 171 177 PF00498 0.272
LIG_FHA_1 223 229 PF00498 0.466
LIG_FHA_1 280 286 PF00498 0.482
LIG_FHA_1 362 368 PF00498 0.396
LIG_FHA_1 376 382 PF00498 0.454
LIG_FHA_1 391 397 PF00498 0.499
LIG_FHA_1 428 434 PF00498 0.514
LIG_FHA_1 622 628 PF00498 0.538
LIG_FHA_1 641 647 PF00498 0.550
LIG_FHA_1 851 857 PF00498 0.286
LIG_FHA_1 898 904 PF00498 0.503
LIG_FHA_1 910 916 PF00498 0.342
LIG_FHA_2 1054 1060 PF00498 0.591
LIG_FHA_2 158 164 PF00498 0.468
LIG_FHA_2 222 228 PF00498 0.497
LIG_FHA_2 490 496 PF00498 0.677
LIG_FHA_2 525 531 PF00498 0.483
LIG_FHA_2 56 62 PF00498 0.675
LIG_FHA_2 594 600 PF00498 0.490
LIG_FHA_2 63 69 PF00498 0.594
LIG_FHA_2 705 711 PF00498 0.520
LIG_FHA_2 753 759 PF00498 0.587
LIG_FHA_2 985 991 PF00498 0.341
LIG_Integrin_RGD_1 701 703 PF01839 0.311
LIG_LIR_Gen_1 1007 1017 PF02991 0.314
LIG_LIR_Gen_1 177 187 PF02991 0.339
LIG_LIR_Gen_1 200 209 PF02991 0.682
LIG_LIR_Gen_1 32 41 PF02991 0.560
LIG_LIR_Gen_1 364 374 PF02991 0.345
LIG_LIR_Gen_1 828 839 PF02991 0.351
LIG_LIR_Gen_1 934 945 PF02991 0.309
LIG_LIR_Gen_1 967 978 PF02991 0.466
LIG_LIR_Gen_1 990 999 PF02991 0.236
LIG_LIR_LC3C_4 240 245 PF02991 0.491
LIG_LIR_Nem_3 1007 1013 PF02991 0.252
LIG_LIR_Nem_3 1078 1084 PF02991 0.667
LIG_LIR_Nem_3 130 135 PF02991 0.456
LIG_LIR_Nem_3 177 182 PF02991 0.328
LIG_LIR_Nem_3 20 26 PF02991 0.763
LIG_LIR_Nem_3 200 206 PF02991 0.594
LIG_LIR_Nem_3 32 36 PF02991 0.630
LIG_LIR_Nem_3 364 369 PF02991 0.483
LIG_LIR_Nem_3 371 375 PF02991 0.481
LIG_LIR_Nem_3 710 714 PF02991 0.536
LIG_LIR_Nem_3 799 805 PF02991 0.495
LIG_LIR_Nem_3 828 834 PF02991 0.351
LIG_LIR_Nem_3 934 940 PF02991 0.309
LIG_LIR_Nem_3 959 964 PF02991 0.501
LIG_LIR_Nem_3 967 973 PF02991 0.455
LIG_LIR_Nem_3 987 991 PF02991 0.256
LIG_NRBOX 344 350 PF00104 0.499
LIG_PCNA_yPIPBox_3 813 823 PF02747 0.470
LIG_PDZ_Class_1 1121 1126 PF00595 0.510
LIG_Pex14_1 1080 1084 PF04695 0.522
LIG_Pex14_1 175 179 PF04695 0.339
LIG_Pex14_2 1029 1033 PF04695 0.656
LIG_Pex14_2 369 373 PF04695 0.482
LIG_Pex14_2 918 922 PF04695 0.276
LIG_Pex14_2 942 946 PF04695 0.401
LIG_Pex14_2 976 980 PF04695 0.344
LIG_PTB_Apo_2 710 717 PF02174 0.583
LIG_PTB_Apo_2 774 781 PF02174 0.509
LIG_PTB_Phospho_1 710 716 PF10480 0.579
LIG_REV1ctd_RIR_1 115 123 PF16727 0.476
LIG_SH2_CRK 629 633 PF00017 0.618
LIG_SH2_CRK 907 911 PF00017 0.327
LIG_SH2_GRB2like 592 595 PF00017 0.550
LIG_SH2_NCK_1 955 959 PF00017 0.522
LIG_SH2_PTP2 831 834 PF00017 0.344
LIG_SH2_SRC 955 958 PF00017 0.522
LIG_SH2_STAP1 1084 1088 PF00017 0.529
LIG_SH2_STAP1 26 30 PF00017 0.719
LIG_SH2_STAT5 251 254 PF00017 0.455
LIG_SH2_STAT5 366 369 PF00017 0.498
LIG_SH2_STAT5 372 375 PF00017 0.500
LIG_SH2_STAT5 444 447 PF00017 0.505
LIG_SH2_STAT5 592 595 PF00017 0.568
LIG_SH2_STAT5 831 834 PF00017 0.344
LIG_SH3_3 121 127 PF00018 0.476
LIG_SH3_3 158 164 PF00018 0.454
LIG_SH3_3 272 278 PF00018 0.385
LIG_SH3_3 379 385 PF00018 0.458
LIG_SH3_3 449 455 PF00018 0.561
LIG_SH3_3 654 660 PF00018 0.550
LIG_SUMO_SIM_anti_2 184 190 PF11976 0.317
LIG_SUMO_SIM_anti_2 378 383 PF11976 0.423
LIG_SUMO_SIM_anti_2 794 800 PF11976 0.504
LIG_SUMO_SIM_anti_2 900 905 PF11976 0.412
LIG_SUMO_SIM_par_1 1004 1009 PF11976 0.415
LIG_SUMO_SIM_par_1 184 190 PF11976 0.315
LIG_SUMO_SIM_par_1 222 230 PF11976 0.474
LIG_SUMO_SIM_par_1 380 386 PF11976 0.461
LIG_SUMO_SIM_par_1 388 393 PF11976 0.462
LIG_SUMO_SIM_par_1 749 755 PF11976 0.511
LIG_SUMO_SIM_par_1 758 763 PF11976 0.479
LIG_SUMO_SIM_par_1 794 800 PF11976 0.497
LIG_SUMO_SIM_par_1 981 987 PF11976 0.313
LIG_TRAF2_1 322 325 PF00917 0.474
LIG_TRAF2_1 872 875 PF00917 0.366
LIG_TRAF2_1 876 879 PF00917 0.499
LIG_TYR_ITIM 370 375 PF00017 0.499
LIG_TYR_ITIM 627 632 PF00017 0.546
LIG_TYR_ITIM 829 834 PF00017 0.344
LIG_UBA3_1 945 953 PF00899 0.280
LIG_WRC_WIRS_1 985 990 PF05994 0.347
MOD_CK1_1 1108 1114 PF00069 0.680
MOD_CK1_1 15 21 PF00069 0.678
MOD_CK1_1 22 28 PF00069 0.645
MOD_CK1_1 262 268 PF00069 0.469
MOD_CK1_1 274 280 PF00069 0.458
MOD_CK1_1 427 433 PF00069 0.514
MOD_CK1_1 50 56 PF00069 0.651
MOD_CK1_1 849 855 PF00069 0.273
MOD_CK2_1 1053 1059 PF00069 0.591
MOD_CK2_1 347 353 PF00069 0.474
MOD_CK2_1 480 486 PF00069 0.551
MOD_CK2_1 489 495 PF00069 0.609
MOD_CK2_1 55 61 PF00069 0.706
MOD_CK2_1 593 599 PF00069 0.473
MOD_CK2_1 62 68 PF00069 0.614
MOD_CK2_1 630 636 PF00069 0.478
MOD_CK2_1 752 758 PF00069 0.586
MOD_GlcNHglycan 1063 1066 PF01048 0.438
MOD_GlcNHglycan 14 17 PF01048 0.536
MOD_GlcNHglycan 208 213 PF01048 0.438
MOD_GlcNHglycan 290 293 PF01048 0.213
MOD_GlcNHglycan 340 343 PF01048 0.229
MOD_GlcNHglycan 563 566 PF01048 0.285
MOD_GlcNHglycan 632 635 PF01048 0.435
MOD_GlcNHglycan 783 786 PF01048 0.356
MOD_GlcNHglycan 791 794 PF01048 0.333
MOD_GSK3_1 1002 1009 PF00069 0.433
MOD_GSK3_1 1104 1111 PF00069 0.709
MOD_GSK3_1 135 142 PF00069 0.519
MOD_GSK3_1 15 22 PF00069 0.607
MOD_GSK3_1 186 193 PF00069 0.311
MOD_GSK3_1 204 211 PF00069 0.598
MOD_GSK3_1 222 229 PF00069 0.481
MOD_GSK3_1 281 288 PF00069 0.455
MOD_GSK3_1 420 427 PF00069 0.504
MOD_GSK3_1 760 767 PF00069 0.508
MOD_GSK3_1 830 837 PF00069 0.327
MOD_GSK3_1 845 852 PF00069 0.298
MOD_GSK3_1 870 877 PF00069 0.310
MOD_GSK3_1 926 933 PF00069 0.339
MOD_GSK3_1 94 101 PF00069 0.556
MOD_LATS_1 577 583 PF00433 0.481
MOD_LATS_1 928 934 PF00433 0.145
MOD_N-GLC_1 420 425 PF02516 0.338
MOD_N-GLC_1 481 486 PF02516 0.314
MOD_N-GLC_1 510 515 PF02516 0.240
MOD_N-GLC_1 593 598 PF02516 0.273
MOD_N-GLC_1 621 626 PF02516 0.318
MOD_N-GLC_1 697 702 PF02516 0.301
MOD_NEK2_1 1015 1020 PF00069 0.203
MOD_NEK2_1 1110 1115 PF00069 0.527
MOD_NEK2_1 1119 1124 PF00069 0.557
MOD_NEK2_1 157 162 PF00069 0.442
MOD_NEK2_1 250 255 PF00069 0.549
MOD_NEK2_1 279 284 PF00069 0.437
MOD_NEK2_1 309 314 PF00069 0.482
MOD_NEK2_1 375 380 PF00069 0.416
MOD_NEK2_1 390 395 PF00069 0.473
MOD_NEK2_1 396 401 PF00069 0.453
MOD_NEK2_1 697 702 PF00069 0.607
MOD_NEK2_1 704 709 PF00069 0.562
MOD_NEK2_1 738 743 PF00069 0.516
MOD_NEK2_1 752 757 PF00069 0.492
MOD_NEK2_1 825 830 PF00069 0.319
MOD_NEK2_1 838 843 PF00069 0.319
MOD_NEK2_1 897 902 PF00069 0.459
MOD_NEK2_1 909 914 PF00069 0.280
MOD_NEK2_1 964 969 PF00069 0.485
MOD_NEK2_1 98 103 PF00069 0.524
MOD_NEK2_1 992 997 PF00069 0.235
MOD_NEK2_2 672 677 PF00069 0.505
MOD_PIKK_1 396 402 PF00454 0.464
MOD_PIKK_1 420 426 PF00454 0.513
MOD_PIKK_1 431 437 PF00454 0.540
MOD_PIKK_1 738 744 PF00454 0.531
MOD_PK_1 271 277 PF00069 0.474
MOD_PKA_1 271 277 PF00069 0.528
MOD_PKA_1 473 479 PF00069 0.403
MOD_PKA_1 561 567 PF00069 0.469
MOD_PKA_1 926 932 PF00069 0.145
MOD_PKA_2 47 53 PF00069 0.715
MOD_PKA_2 473 479 PF00069 0.429
MOD_PKA_2 561 567 PF00069 0.482
MOD_PKA_2 926 932 PF00069 0.292
MOD_PKA_2 997 1003 PF00069 0.204
MOD_PKB_1 1073 1081 PF00069 0.521
MOD_Plk_1 139 145 PF00069 0.513
MOD_Plk_1 221 227 PF00069 0.490
MOD_Plk_1 259 265 PF00069 0.457
MOD_Plk_1 300 306 PF00069 0.476
MOD_Plk_1 420 426 PF00069 0.533
MOD_Plk_1 621 627 PF00069 0.518
MOD_Plk_1 67 73 PF00069 0.519
MOD_Plk_1 930 936 PF00069 0.257
MOD_Plk_1 992 998 PF00069 0.178
MOD_Plk_2-3 222 228 PF00069 0.345
MOD_Plk_2-3 874 880 PF00069 0.506
MOD_Plk_4 1075 1081 PF00069 0.660
MOD_Plk_4 127 133 PF00069 0.457
MOD_Plk_4 139 145 PF00069 0.454
MOD_Plk_4 151 157 PF00069 0.296
MOD_Plk_4 181 187 PF00069 0.320
MOD_Plk_4 253 259 PF00069 0.470
MOD_Plk_4 281 287 PF00069 0.466
MOD_Plk_4 347 353 PF00069 0.485
MOD_Plk_4 362 368 PF00069 0.419
MOD_Plk_4 375 381 PF00069 0.413
MOD_Plk_4 436 442 PF00069 0.509
MOD_Plk_4 52 58 PF00069 0.729
MOD_Plk_4 570 576 PF00069 0.531
MOD_Plk_4 6 12 PF00069 0.670
MOD_Plk_4 647 653 PF00069 0.559
MOD_Plk_4 733 739 PF00069 0.594
MOD_Plk_4 834 840 PF00069 0.315
MOD_Plk_4 909 915 PF00069 0.290
MOD_Plk_4 931 937 PF00069 0.262
MOD_ProDKin_1 237 243 PF00069 0.518
MOD_ProDKin_1 274 280 PF00069 0.376
MOD_ProDKin_1 318 324 PF00069 0.456
MOD_ProDKin_1 846 852 PF00069 0.259
MOD_SUMO_for_1 1029 1032 PF00179 0.581
MOD_SUMO_rev_2 196 203 PF00179 0.483
MOD_SUMO_rev_2 528 536 PF00179 0.418
MOD_SUMO_rev_2 558 563 PF00179 0.465
TRG_AP2beta_CARGO_1 959 968 PF09066 0.345
TRG_DiLeu_BaEn_1 329 334 PF01217 0.516
TRG_DiLeu_BaEn_1 570 575 PF01217 0.483
TRG_DiLeu_BaLyEn_6 1017 1022 PF01217 0.378
TRG_DiLeu_BaLyEn_6 142 147 PF01217 0.435
TRG_ENDOCYTIC_2 1115 1118 PF00928 0.586
TRG_ENDOCYTIC_2 366 369 PF00928 0.473
TRG_ENDOCYTIC_2 372 375 PF00928 0.464
TRG_ENDOCYTIC_2 444 447 PF00928 0.487
TRG_ENDOCYTIC_2 629 632 PF00928 0.525
TRG_ENDOCYTIC_2 831 834 PF00928 0.457
TRG_ENDOCYTIC_2 85 88 PF00928 0.562
TRG_ENDOCYTIC_2 907 910 PF00928 0.331
TRG_ENDOCYTIC_2 955 958 PF00928 0.485
TRG_ER_diArg_1 1073 1076 PF00400 0.659
TRG_ER_diArg_1 215 218 PF00400 0.563
TRG_ER_diArg_1 410 412 PF00400 0.568
TRG_ER_diArg_1 45 48 PF00400 0.728
TRG_ER_diArg_1 472 474 PF00400 0.612
TRG_ER_diArg_1 560 563 PF00400 0.519
TRG_ER_diArg_1 895 897 PF00400 0.488
TRG_ER_diArg_1 966 969 PF00400 0.384
TRG_ER_diArg_1 996 999 PF00400 0.328
TRG_NES_CRM1_1 644 656 PF08389 0.553
TRG_NES_CRM1_1 742 758 PF08389 0.521
TRG_NLS_MonoExtC_3 270 276 PF00514 0.418
TRG_NLS_MonoExtN_4 1070 1076 PF00514 0.527
TRG_NLS_MonoExtN_4 270 275 PF00514 0.499
TRG_Pf-PMV_PEXEL_1 307 311 PF00026 0.282
TRG_Pf-PMV_PEXEL_1 356 361 PF00026 0.292
TRG_Pf-PMV_PEXEL_1 473 477 PF00026 0.376
TRG_Pf-PMV_PEXEL_1 712 717 PF00026 0.345
TRG_Pf-PMV_PEXEL_1 952 956 PF00026 0.265

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P3Y1 Leptomonas seymouri 29% 100%
A0A0N1HWG6 Leptomonas seymouri 40% 100%
A0A0N1PFH3 Leptomonas seymouri 27% 93%
A0A0S4J5A1 Bodo saltans 30% 100%
A0A0S4J6U4 Bodo saltans 39% 100%
A0A0S4JA92 Bodo saltans 42% 100%
A0A0S4JDQ9 Bodo saltans 22% 100%
A0A0S4JRV4 Bodo saltans 41% 100%
A0A0S4KIG5 Bodo saltans 29% 100%
A0A0S4KNQ6 Bodo saltans 62% 100%
A0A1X0NNY6 Trypanosomatidae 28% 100%
A0A1X0NPD9 Trypanosomatidae 64% 100%
A0A1X0NTI6 Trypanosomatidae 40% 99%
A0A1X0P0Y8 Trypanosomatidae 36% 100%
A0A1X0P689 Trypanosomatidae 27% 100%
A0A381MFJ0 Leishmania infantum 24% 100%
A0A3R7KM63 Trypanosoma rangeli 67% 100%
A0A3R7MRX8 Trypanosoma rangeli 28% 100%
A0A3S5H5Y9 Leishmania donovani 89% 100%
A0A3S5IRL5 Trypanosoma rangeli 24% 100%
A0A3S5ISK9 Trypanosoma rangeli 36% 100%
A0A3S7WPW0 Leishmania donovani 82% 100%
A0A3S7WUG2 Leishmania donovani 39% 99%
A0A3S7WV61 Leishmania donovani 24% 100%
A0A3S7WV68 Leishmania donovani 24% 100%
A0A3S7X978 Leishmania donovani 26% 100%
A0A422NTS7 Trypanosoma rangeli 30% 100%
A0A451EJU6 Leishmania donovani 28% 100%
A2VDL6 Bos taurus 28% 100%
A4H3S2 Leishmania braziliensis 28% 100%
A4H903 Leishmania braziliensis 39% 100%
A4H9Q5 Leishmania braziliensis 24% 100%
A4HMM8 Leishmania braziliensis 28% 100%
A4HRZ6 Leishmania infantum 28% 100%
A4HT82 Leishmania infantum 82% 100%
A4HTF0 Leishmania infantum 91% 100%
A4HXD4 Leishmania infantum 39% 99%
A4HY23 Leishmania infantum 24% 100%
A4IBA6 Leishmania infantum 26% 100%
A7L9Z8 Mus musculus 28% 100%
C9ZPL1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
C9ZUN6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 60% 100%
C9ZZN4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 100%
D0A4V8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
D0ZTB2 Salmonella typhimurium (strain 14028s / SGSC 2262) 25% 100%
D2WKD8 Sus scrofa 28% 100%
D3K0R6 Bos taurus 36% 93%
E9AF31 Leishmania major 26% 100%
E9AJY3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 28% 100%
E9AL76 Leishmania mexicana (strain MHOM/GT/2001/U1103) 89% 100%
E9AL78 Leishmania mexicana (strain MHOM/GT/2001/U1103) 82% 100%
E9AR29 Leishmania mexicana (strain MHOM/GT/2001/U1103) 39% 99%
E9ART6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 25% 100%
E9B686 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 92%
G5E829 Mus musculus 39% 92%
J9VQQ3 Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) 38% 80%
O14022 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 20% 100%
O14983 Homo sapiens 29% 100%
O22218 Arabidopsis thaliana 37% 100%
O23087 Arabidopsis thaliana 27% 100%
O34431 Bacillus subtilis (strain 168) 30% 100%
O43108 Yarrowia lipolytica (strain CLIB 122 / E 150) 29% 100%
O46674 Canis lupus familiaris 27% 100%
O55143 Mus musculus 27% 100%
O59868 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 30% 100%
O64806 Arabidopsis thaliana 38% 100%
O75185 Homo sapiens 27% 100%
O77696 Sus scrofa 29% 100%
O81108 Arabidopsis thaliana 38% 100%
P04074 Ovis aries 27% 100%
P04191 Oryctolagus cuniculus 28% 100%
P05023 Homo sapiens 27% 100%
P05024 Sus scrofa 27% 100%
P05025 Tetronarce californica 28% 100%
P06685 Rattus norvegicus 28% 100%
P06686 Rattus norvegicus 29% 100%
P06687 Rattus norvegicus 28% 100%
P09572 Gallus gallus 28% 100%
P09626 Rattus norvegicus 26% 100%
P09627 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 25% 100%
P0ABB8 Escherichia coli (strain K12) 25% 100%
P0ABB9 Escherichia coli O157:H7 25% 100%
P11505 Rattus norvegicus 39% 92%
P11506 Rattus norvegicus 38% 91%
P11507 Rattus norvegicus 27% 100%
P11607 Sus scrofa 27% 100%
P13585 Gallus gallus 28% 100%
P13586 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 30% 100%
P13637 Homo sapiens 28% 100%
P16615 Homo sapiens 27% 100%
P17326 Artemia franciscana 28% 100%
P18596 Rattus norvegicus 29% 100%
P18907 Equus caballus 27% 100%
P19156 Sus scrofa 26% 100%
P20020 Homo sapiens 38% 92%
P20647 Oryctolagus cuniculus 27% 100%
P20648 Homo sapiens 26% 100%
P22036 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 25% 100%
P22189 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 27% 100%
P22700 Drosophila melanogaster 27% 100%
P23220 Sus scrofa 38% 92%
P23634 Homo sapiens 40% 91%
P24797 Gallus gallus 29% 100%
P24798 Gallus gallus 28% 100%
P25489 Catostomus commersonii 28% 100%
P27112 Oryctolagus cuniculus 26% 100%
P28774 Artemia franciscana 29% 100%
P30714 Rhinella marina 27% 100%
P35315 Trypanosoma brucei brucei 30% 100%
P35316 Artemia franciscana 27% 100%
P35317 Hydra vulgaris 29% 100%
P36640 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 25% 100%
P37278 Synechococcus elongatus (strain PCC 7942 / FACHB-805) 30% 100%
P37367 Synechocystis sp. (strain PCC 6803 / Kazusa) 28% 100%
P38929 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 34% 96%
P47317 Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37) 27% 100%
P49380 Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) 26% 100%
P50993 Homo sapiens 29% 100%
P50996 Canis lupus familiaris 26% 100%
P50997 Canis lupus familiaris 27% 100%
P54209 Dunaliella bioculata 29% 100%
P54211 Dunaliella bioculata 24% 100%
P54678 Dictyostelium discoideum 39% 100%
P54707 Homo sapiens 27% 100%
P54708 Rattus norvegicus 27% 100%
P57709 Bos taurus 28% 100%
P58312 Oreochromis mossambicus 27% 100%
P63688 Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) 30% 100%
P70083 Makaira nigricans 29% 100%
P78036 Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) 28% 100%
P92939 Arabidopsis thaliana 28% 100%
P98194 Homo sapiens 27% 100%
P9WPS8 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) 30% 100%
P9WPS9 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 30% 100%
Q00779 Felis catus 27% 100%
Q00804 Oryctolagus cuniculus 38% 92%
Q01814 Homo sapiens 38% 91%
Q03669 Gallus gallus 27% 100%
Q07421 Ajellomyces capsulatus 24% 100%
Q08DA1 Bos taurus 27% 100%
Q0VCY0 Bos taurus 29% 100%
Q16720 Homo sapiens 36% 92%
Q21286 Caenorhabditis elegans 22% 94%
Q292Q0 Drosophila pseudoobscura pseudoobscura 28% 100%
Q2QMX9 Oryza sativa subsp. japonica 37% 100%
Q2QY12 Oryza sativa subsp. japonica 38% 100%
Q2RAS0 Oryza sativa subsp. japonica 38% 100%
Q37145 Arabidopsis thaliana 37% 100%
Q4QDN7 Leishmania major 24% 100%
Q4QDN8 Leishmania major 24% 100%
Q4QED4 Leishmania major 40% 100%
Q4QIM6 Leishmania major 81% 100%
Q4QIM8 Leishmania major 88% 100%
Q4VNC1 Homo sapiens 22% 94%
Q5R5K5 Pongo abelii 28% 100%
Q5RCD8 Pongo abelii 29% 100%
Q5RDR3 Pongo abelii 28% 100%
Q5XF90 Mus musculus 23% 94%
Q5ZKB7 Gallus gallus 21% 94%
Q64392 Cavia porcellus 26% 100%
Q64518 Mus musculus 29% 100%
Q64541 Rattus norvegicus 28% 100%
Q64542 Rattus norvegicus 36% 94%
Q64566 Rattus norvegicus 27% 100%
Q64568 Rattus norvegicus 37% 90%
Q64578 Rattus norvegicus 28% 100%
Q65X71 Oryza sativa subsp. japonica 36% 100%
Q6ATV4 Oryza sativa subsp. japonica 38% 100%
Q6PIC6 Mus musculus 28% 100%
Q6PIE5 Mus musculus 29% 100%
Q6Q477 Mus musculus 36% 93%
Q6RWA9 Taenia solium 29% 100%
Q73E41 Bacillus cereus (strain ATCC 10987 / NRS 248) 29% 100%
Q7PPA5 Anopheles gambiae 28% 100%
Q7X8B5 Oryza sativa subsp. japonica 36% 100%
Q7XEK4 Oryza sativa subsp. japonica 37% 100%
Q80XR2 Mus musculus 27% 100%
Q8R429 Mus musculus 28% 100%
Q8RUN1 Oryza sativa subsp. japonica 38% 100%
Q8VDN2 Mus musculus 27% 100%
Q8Y8Q5 Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) 30% 100%
Q92030 Anguilla anguilla 28% 100%
Q92036 Rhinella marina 26% 100%
Q92105 Pelophylax lessonae 29% 100%
Q92123 Xenopus laevis 28% 100%
Q92126 Xenopus laevis 27% 100%
Q93084 Homo sapiens 29% 100%
Q95Z93 Leishmania major 28% 100%
Q98SH2 Gallus gallus 37% 93%
Q9CFU9 Lactococcus lactis subsp. lactis (strain IL1403) 28% 100%
Q9HDW7 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 39% 87%
Q9LF79 Arabidopsis thaliana 36% 100%
Q9LIK7 Arabidopsis thaliana 35% 100%
Q9LU41 Arabidopsis thaliana 36% 100%
Q9LY77 Arabidopsis thaliana 37% 100%
Q9M2A0 Arabidopsis thaliana 23% 100%
Q9M2L4 Arabidopsis thaliana 38% 100%
Q9N0Z6 Oryctolagus cuniculus 28% 100%
Q9NQ11 Homo sapiens 24% 95%
Q9R0K7 Mus musculus 36% 94%
Q9SH76 Arabidopsis thaliana 22% 100%
Q9SY55 Arabidopsis thaliana 27% 100%
Q9SZR1 Arabidopsis thaliana 37% 100%
Q9TV52 Oryctolagus cuniculus 27% 100%
Q9WV27 Mus musculus 28% 100%
Q9XES1 Arabidopsis thaliana 28% 100%
Q9YGL9 Gallus gallus 29% 100%
Q9YH26 Oreochromis mossambicus 28% 100%
Q9Z1W8 Mus musculus 27% 100%
V5B873 Trypanosoma cruzi 63% 100%
V5BHZ2 Trypanosoma cruzi 27% 100%
V5BLM1 Trypanosoma cruzi 30% 100%
V5BPC6 Trypanosoma cruzi 35% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS