LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4H512_LEIBR
TriTrypDb:
LbrM.07.0680 , LBRM2903_070013300 *
Length:
253

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H512
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H512

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 12 16 PF00656 0.734
CLV_MEL_PAP_1 116 122 PF00089 0.506
CLV_NRD_NRD_1 22 24 PF00675 0.524
CLV_PCSK_KEX2_1 154 156 PF00082 0.629
CLV_PCSK_KEX2_1 218 220 PF00082 0.790
CLV_PCSK_KEX2_1 22 24 PF00082 0.524
CLV_PCSK_PC1ET2_1 154 156 PF00082 0.629
CLV_PCSK_PC1ET2_1 218 220 PF00082 0.774
DEG_SPOP_SBC_1 132 136 PF00917 0.740
DEG_SPOP_SBC_1 137 141 PF00917 0.696
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P403 Leptomonas seymouri 46% 97%
A0A3S5H5Y8 Leishmania donovani 66% 100%
A4HT86 Leishmania infantum 67% 100%
C9ZUN8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 27% 100%
E9AL74 Leishmania mexicana (strain MHOM/GT/2001/U1103) 61% 99%
Q4QIN0 Leishmania major 66% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS