Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H504_LEIBR

TriTrypDb:

LbrM.07.0600 , LBRM2903_070012400

Length:

820

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H504

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H504

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	258	262	PF00656	0.837
CLV_C14_Caspase3-7	351	355	PF00656	0.828
CLV_C14_Caspase3-7	587	591	PF00656	0.769
CLV_C14_Caspase3-7	752	756	PF00656	0.765
CLV_NRD_NRD_1	128	130	PF00675	0.706
CLV_NRD_NRD_1	224	226	PF00675	0.562
CLV_NRD_NRD_1	259	261	PF00675	0.750
CLV_NRD_NRD_1	281	283	PF00675	0.777
CLV_NRD_NRD_1	357	359	PF00675	0.815
CLV_NRD_NRD_1	438	440	PF00675	0.833
CLV_NRD_NRD_1	578	580	PF00675	0.721
CLV_NRD_NRD_1	601	603	PF00675	0.768
CLV_NRD_NRD_1	650	652	PF00675	0.539
CLV_NRD_NRD_1	774	776	PF00675	0.603
CLV_PCSK_FUR_1	257	261	PF00082	0.748
CLV_PCSK_FUR_1	576	580	PF00082	0.837
CLV_PCSK_FUR_1	692	696	PF00082	0.660
CLV_PCSK_KEX2_1	128	130	PF00082	0.732
CLV_PCSK_KEX2_1	224	226	PF00082	0.562
CLV_PCSK_KEX2_1	259	261	PF00082	0.750
CLV_PCSK_KEX2_1	281	283	PF00082	0.777
CLV_PCSK_KEX2_1	357	359	PF00082	0.815
CLV_PCSK_KEX2_1	578	580	PF00082	0.721
CLV_PCSK_KEX2_1	601	603	PF00082	0.768
CLV_PCSK_KEX2_1	625	627	PF00082	0.607
CLV_PCSK_KEX2_1	650	652	PF00082	0.539
CLV_PCSK_KEX2_1	694	696	PF00082	0.684
CLV_PCSK_KEX2_1	774	776	PF00082	0.603
CLV_PCSK_PC1ET2_1	625	627	PF00082	0.542
CLV_PCSK_PC1ET2_1	694	696	PF00082	0.779
CLV_PCSK_PC7_1	124	130	PF00082	0.707
CLV_PCSK_SKI1_1	514	518	PF00082	0.839
CLV_PCSK_SKI1_1	610	614	PF00082	0.666
CLV_PCSK_SKI1_1	626	630	PF00082	0.377
CLV_PCSK_SKI1_1	816	820	PF00082	0.649
CLV_Separin_Metazoa	60	64	PF03568	0.822
DEG_Kelch_Keap1_1	592	597	PF01344	0.832
DEG_SPOP_SBC_1	133	137	PF00917	0.819
DEG_SPOP_SBC_1	139	143	PF00917	0.733
DEG_SPOP_SBC_1	535	539	PF00917	0.829
DOC_CKS1_1	310	315	PF01111	0.816
DOC_CKS1_1	678	683	PF01111	0.642
DOC_MAPK_gen_1	625	634	PF00069	0.512
DOC_MAPK_gen_1	636	643	PF00069	0.490
DOC_MAPK_gen_1	650	656	PF00069	0.266
DOC_USP7_MATH_1	156	160	PF00917	0.797
DOC_USP7_MATH_1	280	284	PF00917	0.804
DOC_USP7_MATH_1	337	341	PF00917	0.735
DOC_USP7_MATH_1	470	474	PF00917	0.735
DOC_USP7_MATH_1	496	500	PF00917	0.743
DOC_USP7_MATH_1	534	538	PF00917	0.820
DOC_USP7_MATH_1	693	697	PF00917	0.774
DOC_USP7_MATH_1	75	79	PF00917	0.785
DOC_USP7_UBL2_3	625	629	PF12436	0.531
DOC_WW_Pin1_4	11	16	PF00397	0.794
DOC_WW_Pin1_4	309	314	PF00397	0.753
DOC_WW_Pin1_4	430	435	PF00397	0.752
DOC_WW_Pin1_4	444	449	PF00397	0.813
DOC_WW_Pin1_4	478	483	PF00397	0.696
DOC_WW_Pin1_4	505	510	PF00397	0.827
DOC_WW_Pin1_4	52	57	PF00397	0.707
DOC_WW_Pin1_4	677	682	PF00397	0.626
DOC_WW_Pin1_4	87	92	PF00397	0.788
LIG_14-3-3_CanoR_1	20	25	PF00244	0.667
LIG_14-3-3_CanoR_1	281	287	PF00244	0.784
LIG_14-3-3_CanoR_1	498	504	PF00244	0.832
LIG_14-3-3_CanoR_1	733	742	PF00244	0.511
LIG_14-3-3_CanoR_1	8	13	PF00244	0.744
LIG_14-3-3_CanoR_1	814	819	PF00244	0.490
LIG_BIR_III_2	457	461	PF00653	0.786
LIG_BIR_III_4	590	594	PF00653	0.826
LIG_BRCT_BRCA1_1	507	511	PF00533	0.827
LIG_Clathr_ClatBox_1	721	725	PF01394	0.556
LIG_DLG_GKlike_1	20	27	PF00625	0.785
LIG_FHA_1	384	390	PF00498	0.770
LIG_FHA_1	391	397	PF00498	0.682
LIG_FHA_1	404	410	PF00498	0.466
LIG_FHA_1	420	426	PF00498	0.500
LIG_FHA_1	466	472	PF00498	0.792
LIG_FHA_1	638	644	PF00498	0.597
LIG_FHA_2	349	355	PF00498	0.824
LIG_LIR_Apic_2	120	126	PF02991	0.815
LIG_LIR_Apic_2	371	375	PF02991	0.798
LIG_LIR_Apic_2	57	62	PF02991	0.786
LIG_LIR_Apic_2	677	681	PF02991	0.606
LIG_LIR_Gen_1	108	117	PF02991	0.694
LIG_LIR_Gen_1	528	535	PF02991	0.834
LIG_LIR_Gen_1	736	744	PF02991	0.612
LIG_LIR_Nem_3	108	114	PF02991	0.696
LIG_LIR_Nem_3	215	220	PF02991	0.531
LIG_LIR_Nem_3	696	701	PF02991	0.773
LIG_LIR_Nem_3	736	742	PF02991	0.617
LIG_MYND_1	130	134	PF01753	0.693
LIG_NRBOX	23	29	PF00104	0.785
LIG_PDZ_Class_2	815	820	PF00595	0.514
LIG_PTAP_UEV_1	523	528	PF05743	0.816
LIG_SH2_CRK	217	221	PF00017	0.524
LIG_SH2_CRK	372	376	PF00017	0.798
LIG_SH2_CRK	698	702	PF00017	0.775
LIG_SH2_CRK	739	743	PF00017	0.593
LIG_SH2_CRK	97	101	PF00017	0.784
LIG_SH2_NCK_1	97	101	PF00017	0.738
LIG_SH2_PTP2	213	216	PF00017	0.514
LIG_SH2_SRC	111	114	PF00017	0.595
LIG_SH2_SRC	59	62	PF00017	0.820
LIG_SH2_SRC	97	100	PF00017	0.735
LIG_SH2_STAP1	186	190	PF00017	0.585
LIG_SH2_STAP1	715	719	PF00017	0.606
LIG_SH2_STAT5	181	184	PF00017	0.535
LIG_SH2_STAT5	213	216	PF00017	0.514
LIG_SH2_STAT5	263	266	PF00017	0.811
LIG_SH2_STAT5	278	281	PF00017	0.530
LIG_SH2_STAT5	645	648	PF00017	0.657
LIG_SH2_STAT5	728	731	PF00017	0.461
LIG_SH3_1	128	134	PF00018	0.699
LIG_SH3_1	246	252	PF00018	0.806
LIG_SH3_2	15	20	PF14604	0.782
LIG_SH3_2	252	257	PF14604	0.692
LIG_SH3_2	524	529	PF14604	0.821
LIG_SH3_2	58	63	PF14604	0.820
LIG_SH3_3	12	18	PF00018	0.680
LIG_SH3_3	128	134	PF00018	0.699
LIG_SH3_3	150	156	PF00018	0.805
LIG_SH3_3	233	239	PF00018	0.649
LIG_SH3_3	246	252	PF00018	0.609
LIG_SH3_3	307	313	PF00018	0.812
LIG_SH3_3	331	337	PF00018	0.713
LIG_SH3_3	498	504	PF00018	0.832
LIG_SH3_3	521	527	PF00018	0.816
LIG_SH3_3	55	61	PF00018	0.820
LIG_SH3_3	621	627	PF00018	0.657
LIG_SH3_3	668	674	PF00018	0.501
LIG_SH3_3	85	91	PF00018	0.686
LIG_SH3_3	93	99	PF00018	0.657
LIG_SUMO_SIM_anti_2	158	164	PF11976	0.793
LIG_SUMO_SIM_par_1	788	794	PF11976	0.550
LIG_TRAF2_1	110	113	PF00917	0.701
LIG_TRAF2_1	615	618	PF00917	0.786
LIG_TRAF2_1	69	72	PF00917	0.824
LIG_TRAF2_1	709	712	PF00917	0.582
LIG_UBA3_1	656	663	PF00899	0.467
LIG_WW_3	60	64	PF00397	0.822
MOD_CDK_SPxxK_3	430	437	PF00069	0.831
MOD_CDK_SPxxK_3	478	485	PF00069	0.699
MOD_CK1_1	11	17	PF00069	0.680
MOD_CK1_1	119	125	PF00069	0.817
MOD_CK1_1	22	28	PF00069	0.674
MOD_CK1_1	362	368	PF00069	0.799
MOD_CK1_1	420	426	PF00069	0.725
MOD_CK1_1	499	505	PF00069	0.814
MOD_CK1_1	525	531	PF00069	0.728
MOD_CK1_1	537	543	PF00069	0.694
MOD_CK1_1	637	643	PF00069	0.606
MOD_CK2_1	350	356	PF00069	0.767
MOD_CK2_1	54	60	PF00069	0.825
MOD_CK2_1	706	712	PF00069	0.573
MOD_Cter_Amidation	599	602	PF01082	0.839
MOD_Cter_Amidation	772	775	PF01082	0.634
MOD_GlcNHglycan	10	13	PF01048	0.798
MOD_GlcNHglycan	146	149	PF01048	0.758
MOD_GlcNHglycan	200	203	PF01048	0.680
MOD_GlcNHglycan	283	286	PF01048	0.724
MOD_GlcNHglycan	33	37	PF01048	0.788
MOD_GlcNHglycan	339	342	PF01048	0.762
MOD_GlcNHglycan	381	384	PF01048	0.787
MOD_GlcNHglycan	524	527	PF01048	0.665
MOD_GlcNHglycan	558	561	PF01048	0.833
MOD_GlcNHglycan	584	587	PF01048	0.731
MOD_GlcNHglycan	620	623	PF01048	0.591
MOD_GlcNHglycan	71	76	PF01048	0.749
MOD_GlcNHglycan	752	755	PF01048	0.739
MOD_GSK3_1	133	140	PF00069	0.826
MOD_GSK3_1	19	26	PF00069	0.622
MOD_GSK3_1	317	324	PF00069	0.752
MOD_GSK3_1	32	39	PF00069	0.764
MOD_GSK3_1	359	366	PF00069	0.719
MOD_GSK3_1	379	386	PF00069	0.782
MOD_GSK3_1	417	424	PF00069	0.736
MOD_GSK3_1	429	436	PF00069	0.601
MOD_GSK3_1	486	493	PF00069	0.772
MOD_GSK3_1	534	541	PF00069	0.755
MOD_GSK3_1	582	589	PF00069	0.725
MOD_GSK3_1	7	14	PF00069	0.715
MOD_GSK3_1	71	78	PF00069	0.789
MOD_GSK3_1	750	757	PF00069	0.760
MOD_GSK3_1	83	90	PF00069	0.615
MOD_N-GLC_1	362	367	PF02516	0.798
MOD_N-GLC_1	449	454	PF02516	0.701
MOD_N-GLC_1	814	819	PF02516	0.490
MOD_N-GLC_1	83	88	PF02516	0.803
MOD_N-GLC_2	174	176	PF02516	0.650
MOD_NEK2_1	19	24	PF00069	0.786
MOD_NEK2_1	216	221	PF00069	0.502
MOD_NEK2_1	229	234	PF00069	0.505
MOD_NEK2_1	272	277	PF00069	0.782
MOD_NEK2_1	359	364	PF00069	0.718
MOD_NEK2_1	379	384	PF00069	0.788
MOD_NEK2_1	419	424	PF00069	0.816
MOD_NEK2_1	517	522	PF00069	0.833
MOD_NEK2_1	634	639	PF00069	0.501
MOD_NEK2_1	706	711	PF00069	0.572
MOD_NEK2_1	738	743	PF00069	0.591
MOD_PIKK_1	117	123	PF00454	0.699
MOD_PIKK_1	261	267	PF00454	0.816
MOD_PIKK_1	332	338	PF00454	0.809
MOD_PIKK_1	517	523	PF00454	0.832
MOD_PIKK_1	706	712	PF00454	0.573
MOD_PKA_1	281	287	PF00069	0.816
MOD_PKA_1	439	445	PF00069	0.840
MOD_PKA_2	19	25	PF00069	0.669
MOD_PKA_2	280	286	PF00069	0.719
MOD_PKA_2	487	493	PF00069	0.831
MOD_PKA_2	499	505	PF00069	0.621
MOD_PKA_2	550	556	PF00069	0.788
MOD_PKA_2	637	643	PF00069	0.606
MOD_PKA_2	666	672	PF00069	0.630
MOD_PKA_2	7	13	PF00069	0.747
MOD_PKB_1	437	445	PF00069	0.838
MOD_Plk_1	229	235	PF00069	0.561
MOD_Plk_1	449	455	PF00069	0.808
MOD_Plk_1	814	820	PF00069	0.510
MOD_Plk_2-3	755	761	PF00069	0.756
MOD_Plk_4	23	29	PF00069	0.668
MOD_Plk_4	230	236	PF00069	0.627
MOD_Plk_4	274	280	PF00069	0.783
MOD_Plk_4	421	427	PF00069	0.815
MOD_Plk_4	738	744	PF00069	0.486
MOD_Plk_4	791	797	PF00069	0.397
MOD_ProDKin_1	11	17	PF00069	0.793
MOD_ProDKin_1	309	315	PF00069	0.746
MOD_ProDKin_1	430	436	PF00069	0.753
MOD_ProDKin_1	444	450	PF00069	0.811
MOD_ProDKin_1	478	484	PF00069	0.697
MOD_ProDKin_1	505	511	PF00069	0.830
MOD_ProDKin_1	52	58	PF00069	0.705
MOD_ProDKin_1	677	683	PF00069	0.630
MOD_ProDKin_1	87	93	PF00069	0.789
MOD_SUMO_for_1	114	117	PF00179	0.735
TRG_DiLeu_BaEn_1	158	163	PF01217	0.796
TRG_DiLeu_BaEn_2	229	235	PF01217	0.736
TRG_DiLeu_BaLyEn_6	630	635	PF01217	0.602
TRG_ENDOCYTIC_2	111	114	PF00928	0.697
TRG_ENDOCYTIC_2	213	216	PF00928	0.514
TRG_ENDOCYTIC_2	217	220	PF00928	0.529
TRG_ENDOCYTIC_2	698	701	PF00928	0.776
TRG_ENDOCYTIC_2	739	742	PF00928	0.598
TRG_ER_diArg_1	127	129	PF00400	0.718
TRG_ER_diArg_1	280	282	PF00400	0.773
TRG_ER_diArg_1	357	359	PF00400	0.815
TRG_ER_diArg_1	498	501	PF00400	0.839
TRG_ER_diArg_1	578	580	PF00400	0.725
TRG_ER_diArg_1	62	65	PF00400	0.827
TRG_ER_diArg_1	635	638	PF00400	0.618
TRG_ER_diArg_1	650	652	PF00400	0.539
TRG_ER_diArg_1	774	776	PF00400	0.603
TRG_NLS_MonoExtN_4	691	698	PF00514	0.774
TRG_Pf-PMV_PEXEL_1	298	302	PF00026	0.805
TRG_Pf-PMV_PEXEL_1	626	630	PF00026	0.523
TRG_Pf-PMV_PEXEL_1	733	737	PF00026	0.651

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I2F0	Leptomonas seymouri	39%	79%