Highly similar to mitochondrial ADP/ATP antiporters of other Eukaryotes.. Only duplicated sporadically in Strigomonas and T. cruzi.. Localization: Mitochondrial inner membrane (by homology)
| Source | Evidence on protein | Close homologs | 
|---|---|---|
| Cuervo et al. | no | yes: 0 | 
| Hassani et al. | no | yes: 0 | 
| Forrest at al. (metacyclic) | no | yes: 0 | 
| Forrest at al. (procyclic) | no | yes: 0 | 
| Silverman et al. | no | yes: 0 | 
| Pissara et al. | no | yes: 0 | 
| Source | Evidence on protein | Close homologs | 
|---|---|---|
| Pires et al. | no | yes: 0 | 
| Source | Evidence on protein | Close homologs | 
|---|---|---|
| Silverman et al. | no | yes: 0 | 
| Source | Evidence on protein | Close homologs | 
|---|---|---|
| Jamdhade et al. | no | yes: 0 | 
| Source | Evidence on protein | Close homologs | 
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 12 | 
| NetGPI | no | yes: 0, no: 12 | 
| Term | Name | Level | Count | 
|---|---|---|---|
| GO:0005743 | mitochondrial inner membrane | 5 | 13 | 
| GO:0016020 | membrane | 2 | 13 | 
| GO:0019866 | organelle inner membrane | 4 | 13 | 
| GO:0031090 | organelle membrane | 3 | 13 | 
| GO:0031966 | mitochondrial membrane | 4 | 13 | 
| GO:0110165 | cellular anatomical entity | 1 | 13 | 
Related structures:
AlphaFold database: A4H503
| Term | Name | Level | Count | 
|---|---|---|---|
| GO:0006810 | transport | 3 | 13 | 
| GO:0006811 | monoatomic ion transport | 4 | 13 | 
| GO:0006820 | monoatomic anion transport | 5 | 13 | 
| GO:0006862 | nucleotide transport | 6 | 13 | 
| GO:0009987 | cellular process | 1 | 13 | 
| GO:0015711 | organic anion transport | 5 | 13 | 
| GO:0015748 | organophosphate ester transport | 5 | 13 | 
| GO:0015865 | purine nucleotide transport | 7 | 13 | 
| GO:0015866 | ADP transport | 6 | 13 | 
| GO:0015867 | ATP transport | 6 | 13 | 
| GO:0015868 | purine ribonucleotide transport | 6 | 13 | 
| GO:0015931 | nucleobase-containing compound transport | 5 | 13 | 
| GO:0034220 | monoatomic ion transmembrane transport | 3 | 13 | 
| GO:0051179 | localization | 1 | 13 | 
| GO:0051234 | establishment of localization | 2 | 13 | 
| GO:0051503 | adenine nucleotide transport | 8 | 13 | 
| GO:0055085 | transmembrane transport | 2 | 13 | 
| GO:0071702 | organic substance transport | 4 | 13 | 
| GO:0071705 | nitrogen compound transport | 4 | 13 | 
| GO:0072530 | purine-containing compound transmembrane transport | 3 | 13 | 
| GO:0098656 | monoatomic anion transmembrane transport | 4 | 13 | 
| GO:0140021 | mitochondrial ADP transmembrane transport | 4 | 13 | 
| GO:1901264 | carbohydrate derivative transport | 5 | 13 | 
| GO:1901679 | nucleotide transmembrane transport | 3 | 13 | 
| GO:1990542 | mitochondrial transmembrane transport | 3 | 13 | 
| GO:1990544 | mitochondrial ATP transmembrane transport | 4 | 13 | 
| GO:0006996 | organelle organization | 4 | 1 | 
| GO:0007005 | mitochondrion organization | 5 | 1 | 
| GO:0007006 | mitochondrial membrane organization | 5 | 1 | 
| GO:0009966 | regulation of signal transduction | 4 | 1 | 
| GO:0009968 | negative regulation of signal transduction | 5 | 1 | 
| GO:0010639 | negative regulation of organelle organization | 6 | 1 | 
| GO:0010646 | regulation of cell communication | 4 | 1 | 
| GO:0010648 | negative regulation of cell communication | 5 | 1 | 
| GO:0010821 | regulation of mitochondrion organization | 6 | 1 | 
| GO:0010823 | negative regulation of mitochondrion organization | 7 | 1 | 
| GO:0010941 | regulation of cell death | 4 | 1 | 
| GO:0016043 | cellular component organization | 3 | 1 | 
| GO:0023051 | regulation of signaling | 3 | 1 | 
| GO:0023057 | negative regulation of signaling | 4 | 1 | 
| GO:0032879 | regulation of localization | 3 | 1 | 
| GO:0033043 | regulation of organelle organization | 5 | 1 | 
| GO:0035795 | negative regulation of mitochondrial membrane permeability | 5 | 1 | 
| GO:0042981 | regulation of apoptotic process | 6 | 1 | 
| GO:0043066 | negative regulation of apoptotic process | 7 | 1 | 
| GO:0043067 | regulation of programmed cell death | 5 | 1 | 
| GO:0043069 | negative regulation of programmed cell death | 6 | 1 | 
| GO:0046902 | regulation of mitochondrial membrane permeability | 4 | 1 | 
| GO:0048519 | negative regulation of biological process | 3 | 1 | 
| GO:0048523 | negative regulation of cellular process | 4 | 1 | 
| GO:0048583 | regulation of response to stimulus | 3 | 1 | 
| GO:0048585 | negative regulation of response to stimulus | 4 | 1 | 
| GO:0050789 | regulation of biological process | 2 | 1 | 
| GO:0050794 | regulation of cellular process | 3 | 1 | 
| GO:0051049 | regulation of transport | 4 | 1 | 
| GO:0051128 | regulation of cellular component organization | 4 | 1 | 
| GO:0051129 | negative regulation of cellular component organization | 5 | 1 | 
| GO:0060548 | negative regulation of cell death | 5 | 1 | 
| GO:0061024 | membrane organization | 4 | 1 | 
| GO:0065007 | biological regulation | 1 | 1 | 
| GO:0065008 | regulation of biological quality | 2 | 1 | 
| GO:0071840 | cellular component organization or biogenesis | 2 | 1 | 
| GO:0090559 | regulation of membrane permeability | 3 | 1 | 
| GO:1901028 | regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | 5 | 1 | 
| GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | 6 | 1 | 
| GO:1905709 | negative regulation of membrane permeability | 4 | 1 | 
| GO:2001233 | regulation of apoptotic signaling pathway | 5 | 1 | 
| GO:2001234 | negative regulation of apoptotic signaling pathway | 6 | 1 | 
| Term | Name | Level | Count | 
|---|---|---|---|
| GO:0000295 | adenine nucleotide transmembrane transporter activity | 6 | 13 | 
| GO:0005215 | transporter activity | 1 | 13 | 
| GO:0005346 | purine ribonucleotide transmembrane transporter activity | 4 | 13 | 
| GO:0005347 | ATP transmembrane transporter activity | 5 | 13 | 
| GO:0005471 | ATP:ADP antiporter activity | 5 | 13 | 
| GO:0008509 | monoatomic anion transmembrane transporter activity | 4 | 13 | 
| GO:0008514 | organic anion transmembrane transporter activity | 5 | 13 | 
| GO:0015075 | monoatomic ion transmembrane transporter activity | 3 | 13 | 
| GO:0015215 | nucleotide transmembrane transporter activity | 4 | 13 | 
| GO:0015216 | purine nucleotide transmembrane transporter activity | 5 | 13 | 
| GO:0015217 | ADP transmembrane transporter activity | 5 | 13 | 
| GO:0015291 | secondary active transmembrane transporter activity | 4 | 13 | 
| GO:0015297 | antiporter activity | 5 | 13 | 
| GO:0015605 | organophosphate ester transmembrane transporter activity | 3 | 13 | 
| GO:0015932 | nucleobase-containing compound transmembrane transporter activity | 3 | 13 | 
| GO:0022804 | active transmembrane transporter activity | 3 | 13 | 
| GO:0022853 | active monoatomic ion transmembrane transporter activity | 4 | 13 | 
| GO:0022857 | transmembrane transporter activity | 2 | 13 | 
| GO:0140323 | obsolete solute:monoatomic anion antiporter activity | 6 | 13 | 
| GO:1901505 | carbohydrate derivative transmembrane transporter activity | 3 | 13 | 
| Leishmania | From | To | Domain/Motif | Score | 
|---|---|---|---|---|
| CLV_PCSK_SKI1_1 | 24 | 28 | PF00082 | 0.524 | 
| CLV_PCSK_SKI1_1 | 241 | 245 | PF00082 | 0.396 | 
| CLV_PCSK_SKI1_1 | 336 | 340 | PF00082 | 0.273 | 
| CLV_PCSK_SKI1_1 | 348 | 352 | PF00082 | 0.329 | 
| CLV_PCSK_SKI1_1 | 88 | 92 | PF00082 | 0.258 | 
| DEG_APCC_DBOX_1 | 137 | 145 | PF00400 | 0.407 | 
| DEG_APCC_DBOX_1 | 87 | 95 | PF00400 | 0.517 | 
| DEG_MDM2_SWIB_1 | 117 | 124 | PF02201 | 0.517 | 
| DOC_CYCLIN_yCln2_LP_2 | 263 | 269 | PF00134 | 0.311 | 
| DOC_MAPK_gen_1 | 203 | 210 | PF00069 | 0.416 | 
| DOC_MAPK_gen_1 | 305 | 312 | PF00069 | 0.458 | 
| DOC_MAPK_MEF2A_6 | 203 | 210 | PF00069 | 0.416 | 
| DOC_MAPK_MEF2A_6 | 305 | 312 | PF00069 | 0.458 | 
| DOC_PP2B_LxvP_1 | 263 | 266 | PF13499 | 0.335 | 
| DOC_USP7_MATH_1 | 160 | 164 | PF00917 | 0.308 | 
| DOC_USP7_MATH_1 | 18 | 22 | PF00917 | 0.666 | 
| DOC_USP7_MATH_1 | 2 | 6 | PF00917 | 0.680 | 
| DOC_USP7_MATH_1 | 230 | 234 | PF00917 | 0.453 | 
| DOC_USP7_MATH_1 | 42 | 46 | PF00917 | 0.737 | 
| DOC_USP7_MATH_1 | 50 | 54 | PF00917 | 0.677 | 
| DOC_USP7_MATH_1 | 8 | 12 | PF00917 | 0.645 | 
| DOC_USP7_MATH_2 | 270 | 276 | PF00917 | 0.379 | 
| DOC_WW_Pin1_4 | 275 | 280 | PF00397 | 0.274 | 
| DOC_WW_Pin1_4 | 44 | 49 | PF00397 | 0.680 | 
| LIG_14-3-3_CanoR_1 | 221 | 225 | PF00244 | 0.427 | 
| LIG_14-3-3_CanoR_1 | 24 | 31 | PF00244 | 0.736 | 
| LIG_14-3-3_CanoR_1 | 241 | 246 | PF00244 | 0.120 | 
| LIG_14-3-3_CanoR_1 | 316 | 326 | PF00244 | 0.426 | 
| LIG_BRCT_BRCA1_1 | 162 | 166 | PF00533 | 0.315 | 
| LIG_BRCT_BRCA1_1 | 216 | 220 | PF00533 | 0.433 | 
| LIG_BRCT_BRCA1_1 | 222 | 226 | PF00533 | 0.422 | 
| LIG_Clathr_ClatBox_1 | 71 | 75 | PF01394 | 0.618 | 
| LIG_CtBP_PxDLS_1 | 300 | 304 | PF00389 | 0.517 | 
| LIG_eIF4E_1 | 240 | 246 | PF01652 | 0.311 | 
| LIG_FHA_1 | 1 | 7 | PF00498 | 0.683 | 
| LIG_FHA_1 | 169 | 175 | PF00498 | 0.285 | 
| LIG_FHA_1 | 242 | 248 | PF00498 | 0.328 | 
| LIG_FHA_1 | 276 | 282 | PF00498 | 0.257 | 
| LIG_FHA_1 | 291 | 297 | PF00498 | 0.193 | 
| LIG_FHA_1 | 341 | 347 | PF00498 | 0.296 | 
| LIG_FHA_1 | 351 | 357 | PF00498 | 0.225 | 
| LIG_LIR_Gen_1 | 119 | 127 | PF02991 | 0.459 | 
| LIG_LIR_Gen_1 | 181 | 190 | PF02991 | 0.309 | 
| LIG_LIR_Gen_1 | 200 | 208 | PF02991 | 0.416 | 
| LIG_LIR_Gen_1 | 250 | 261 | PF02991 | 0.277 | 
| LIG_LIR_Nem_3 | 116 | 120 | PF02991 | 0.447 | 
| LIG_LIR_Nem_3 | 181 | 185 | PF02991 | 0.309 | 
| LIG_LIR_Nem_3 | 200 | 204 | PF02991 | 0.415 | 
| LIG_LIR_Nem_3 | 223 | 227 | PF02991 | 0.472 | 
| LIG_LIR_Nem_3 | 250 | 256 | PF02991 | 0.298 | 
| LIG_Pex14_2 | 117 | 121 | PF04695 | 0.440 | 
| LIG_Pex14_2 | 164 | 168 | PF04695 | 0.276 | 
| LIG_Pex14_2 | 220 | 224 | PF04695 | 0.517 | 
| LIG_REV1ctd_RIR_1 | 336 | 344 | PF16727 | 0.483 | 
| LIG_SH2_CRK | 182 | 186 | PF00017 | 0.314 | 
| LIG_SH2_CRK | 240 | 244 | PF00017 | 0.267 | 
| LIG_SH2_CRK | 253 | 257 | PF00017 | 0.222 | 
| LIG_SH2_NCK_1 | 177 | 181 | PF00017 | 0.309 | 
| LIG_SH2_PTP2 | 267 | 270 | PF00017 | 0.400 | 
| LIG_SH2_SRC | 267 | 270 | PF00017 | 0.400 | 
| LIG_SH2_STAP1 | 182 | 186 | PF00017 | 0.265 | 
| LIG_SH2_STAP1 | 319 | 323 | PF00017 | 0.458 | 
| LIG_SH2_STAT3 | 159 | 162 | PF00017 | 0.363 | 
| LIG_SH2_STAT3 | 99 | 102 | PF00017 | 0.483 | 
| LIG_SH2_STAT5 | 126 | 129 | PF00017 | 0.517 | 
| LIG_SH2_STAT5 | 177 | 180 | PF00017 | 0.279 | 
| LIG_SH2_STAT5 | 267 | 270 | PF00017 | 0.353 | 
| LIG_SH2_STAT5 | 76 | 79 | PF00017 | 0.531 | 
| LIG_SH2_STAT5 | 99 | 102 | PF00017 | 0.483 | 
| LIG_SH3_3 | 192 | 198 | PF00018 | 0.254 | 
| LIG_SH3_3 | 263 | 269 | PF00018 | 0.291 | 
| LIG_SH3_3 | 355 | 361 | PF00018 | 0.164 | 
| LIG_SH3_3 | 87 | 93 | PF00018 | 0.517 | 
| LIG_SUMO_SIM_anti_2 | 353 | 359 | PF11976 | 0.164 | 
| LIG_SUMO_SIM_anti_2 | 65 | 73 | PF11976 | 0.491 | 
| LIG_SUMO_SIM_par_1 | 308 | 315 | PF11976 | 0.515 | 
| LIG_SUMO_SIM_par_1 | 342 | 347 | PF11976 | 0.396 | 
| LIG_SUMO_SIM_par_1 | 70 | 75 | PF11976 | 0.588 | 
| LIG_TRAF2_1 | 270 | 273 | PF00917 | 0.438 | 
| LIG_TYR_ITIM | 238 | 243 | PF00017 | 0.234 | 
| LIG_TYR_ITIM | 251 | 256 | PF00017 | 0.278 | 
| MOD_CK1_1 | 122 | 128 | PF00069 | 0.351 | 
| MOD_CK1_1 | 25 | 31 | PF00069 | 0.723 | 
| MOD_CK1_1 | 275 | 281 | PF00069 | 0.244 | 
| MOD_CK1_1 | 291 | 297 | PF00069 | 0.221 | 
| MOD_CK1_1 | 44 | 50 | PF00069 | 0.763 | 
| MOD_GlcNHglycan | 11 | 14 | PF01048 | 0.554 | 
| MOD_GlcNHglycan | 16 | 19 | PF01048 | 0.537 | 
| MOD_GlcNHglycan | 20 | 23 | PF01048 | 0.536 | 
| MOD_GlcNHglycan | 271 | 277 | PF01048 | 0.603 | 
| MOD_GlcNHglycan | 290 | 293 | PF01048 | 0.205 | 
| MOD_GlcNHglycan | 320 | 323 | PF01048 | 0.240 | 
| MOD_GlcNHglycan | 52 | 55 | PF01048 | 0.481 | 
| MOD_GSK3_1 | 14 | 21 | PF00069 | 0.703 | 
| MOD_GSK3_1 | 22 | 29 | PF00069 | 0.681 | 
| MOD_GSK3_1 | 286 | 293 | PF00069 | 0.326 | 
| MOD_GSK3_1 | 340 | 347 | PF00069 | 0.469 | 
| MOD_N-GLC_2 | 167 | 169 | PF02516 | 0.551 | 
| MOD_NEK2_1 | 130 | 135 | PF00069 | 0.400 | 
| MOD_NEK2_1 | 168 | 173 | PF00069 | 0.248 | 
| MOD_NEK2_1 | 190 | 195 | PF00069 | 0.358 | 
| MOD_NEK2_1 | 220 | 225 | PF00069 | 0.493 | 
| MOD_NEK2_1 | 26 | 31 | PF00069 | 0.685 | 
| MOD_NEK2_1 | 288 | 293 | PF00069 | 0.288 | 
| MOD_NEK2_1 | 317 | 322 | PF00069 | 0.468 | 
| MOD_PIKK_1 | 158 | 164 | PF00454 | 0.273 | 
| MOD_PIKK_1 | 52 | 58 | PF00454 | 0.646 | 
| MOD_PKA_2 | 220 | 226 | PF00069 | 0.416 | 
| MOD_Plk_1 | 175 | 181 | PF00069 | 0.206 | 
| MOD_Plk_1 | 22 | 28 | PF00069 | 0.608 | 
| MOD_Plk_4 | 116 | 122 | PF00069 | 0.557 | 
| MOD_Plk_4 | 143 | 149 | PF00069 | 0.254 | 
| MOD_Plk_4 | 160 | 166 | PF00069 | 0.250 | 
| MOD_Plk_4 | 170 | 176 | PF00069 | 0.316 | 
| MOD_Plk_4 | 190 | 196 | PF00069 | 0.120 | 
| MOD_Plk_4 | 241 | 247 | PF00069 | 0.303 | 
| MOD_Plk_4 | 67 | 73 | PF00069 | 0.638 | 
| MOD_ProDKin_1 | 275 | 281 | PF00069 | 0.274 | 
| MOD_ProDKin_1 | 44 | 50 | PF00069 | 0.679 | 
| TRG_DiLeu_BaEn_1 | 234 | 239 | PF01217 | 0.365 | 
| TRG_ENDOCYTIC_2 | 182 | 185 | PF00928 | 0.340 | 
| TRG_ENDOCYTIC_2 | 201 | 204 | PF00928 | 0.517 | 
| TRG_ENDOCYTIC_2 | 240 | 243 | PF00928 | 0.241 | 
| TRG_ENDOCYTIC_2 | 253 | 256 | PF00928 | 0.241 | 
| TRG_ER_diArg_1 | 304 | 307 | PF00400 | 0.407 | 
| Protein | Taxonomy | Sequence identity | Coverage | 
|---|---|---|---|
| A0A0N0P222 | Leptomonas seymouri | 30% | 100% | 
| A0A0N1P9L0 | Leptomonas seymouri | 74% | 100% | 
| A0A0S4IU86 | Bodo saltans | 44% | 100% | 
| A0A0S4IYL3 | Bodo saltans | 29% | 100% | 
| A0A0S4IZ65 | Bodo saltans | 25% | 100% | 
| A0A0S4IZG7 | Bodo saltans | 25% | 100% | 
| A0A0S4J2G4 | Bodo saltans | 22% | 100% | 
| A0A1X0NPW5 | Trypanosomatidae | 56% | 100% | 
| A0A1X0P6F0 | Trypanosomatidae | 30% | 100% | 
| A0A1X0P6P9 | Trypanosomatidae | 29% | 100% | 
| A0A3Q8IB56 | Leishmania donovani | 28% | 100% | 
| A0A3R7K844 | Trypanosoma rangeli | 32% | 100% | 
| A0A3R7KEL4 | Trypanosoma rangeli | 56% | 100% | 
| A0A3S5H5Y3 | Leishmania donovani | 85% | 99% | 
| A1DI57 | Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) | 25% | 100% | 
| A2A3V2 | Mus musculus | 24% | 100% | 
| A2ASZ8 | Mus musculus | 26% | 77% | 
| A2CEQ0 | Danio rerio | 27% | 77% | 
| A2R5A0 | Aspergillus niger (strain CBS 513.88 / FGSC A1513) | 23% | 100% | 
| A4H9X7 | Leishmania braziliensis | 29% | 100% | 
| A4H9X8 | Leishmania braziliensis | 29% | 100% | 
| A4HT75 | Leishmania infantum | 85% | 99% | 
| A4HY43 | Leishmania infantum | 28% | 100% | 
| A4RF23 | Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) | 24% | 100% | 
| A5PJZ1 | Bos taurus | 26% | 76% | 
| A6RF73 | Ajellomyces capsulatus (strain NAm1 / WU24) | 24% | 100% | 
| A6SL61 | Botryotinia fuckeliana (strain B05.10) | 24% | 100% | 
| A7ER02 | Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) | 23% | 100% | 
| B0G159 | Dictyostelium discoideum | 23% | 77% | 
| B4F8I5 | Zea mays | 25% | 100% | 
| B8ZHC9 | Rattus norvegicus | 24% | 100% | 
| C9ZUP8 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 41% | 100% | 
| D0A0D8 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 29% | 100% | 
| E9AL65 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 84% | 99% | 
| E9ARX1 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 28% | 100% | 
| E9ARX2 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 28% | 100% | 
| F4HW79 | Arabidopsis thaliana | 22% | 100% | 
| F4JU70 | Arabidopsis thaliana | 26% | 100% | 
| G2QNH0 | Myceliophthora thermophila (strain ATCC 42464 / BCRC 31852 / DSM 1799) | 28% | 100% | 
| K7VYZ9 | Zea mays | 26% | 100% | 
| O04619 | Arabidopsis thaliana | 22% | 100% | 
| O18757 | Oryctolagus cuniculus | 25% | 76% | 
| O22342 | Gossypium hirsutum | 28% | 94% | 
| O46373 | Oryctolagus cuniculus | 29% | 100% | 
| O49447 | Arabidopsis thaliana | 29% | 96% | 
| O65023 | Arabidopsis thaliana | 25% | 95% | 
| O94502 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 22% | 85% | 
| O97470 | Dictyostelium discoideum | 29% | 100% | 
| P02722 | Bos taurus | 29% | 100% | 
| P02723 | Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) | 29% | 100% | 
| P04709 | Zea mays | 29% | 94% | 
| P04710 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 29% | 100% | 
| P05141 | Homo sapiens | 30% | 100% | 
| P0C546 | Rattus norvegicus | 24% | 100% | 
| P12235 | Homo sapiens | 28% | 100% | 
| P12236 | Homo sapiens | 28% | 100% | 
| P12857 | Zea mays | 30% | 94% | 
| P16260 | Homo sapiens | 22% | 100% | 
| P18238 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 28% | 100% | 
| P18239 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 29% | 100% | 
| P25083 | Solanum tuberosum | 28% | 94% | 
| P27080 | Chlamydomonas reinhardtii | 29% | 100% | 
| P27081 | Solanum tuberosum | 27% | 94% | 
| P29518 | Zea mays | 23% | 83% | 
| P31167 | Arabidopsis thaliana | 26% | 95% | 
| P31691 | Oryza sativa subsp. japonica | 30% | 95% | 
| P31692 | Parachlorella kessleri | 31% | 100% | 
| P32007 | Bos taurus | 28% | 100% | 
| P40941 | Arabidopsis thaliana | 28% | 94% | 
| P48962 | Mus musculus | 29% | 100% | 
| P49382 | Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) | 28% | 100% | 
| P51881 | Mus musculus | 29% | 100% | 
| Q000K2 | Tachyglossus aculeatus aculeatus | 29% | 100% | 
| Q01888 | Bos taurus | 24% | 100% | 
| Q05962 | Rattus norvegicus | 29% | 100% | 
| Q05AQ3 | Xenopus tropicalis | 28% | 100% | 
| Q09073 | Rattus norvegicus | 29% | 100% | 
| Q09188 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 31% | 100% | 
| Q0CEN9 | Aspergillus terreus (strain NIH 2624 / FGSC A1156) | 23% | 100% | 
| Q0P483 | Danio rerio | 26% | 100% | 
| Q0UUH1 | Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) | 26% | 100% | 
| Q0V7M4 | Bos taurus | 28% | 77% | 
| Q12251 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 25% | 100% | 
| Q19529 | Caenorhabditis elegans | 26% | 68% | 
| Q1E7P0 | Coccidioides immitis (strain RS) | 24% | 100% | 
| Q1ECW7 | Danio rerio | 21% | 100% | 
| Q26365 | Drosophila melanogaster | 28% | 100% | 
| Q27238 | Anopheles gambiae | 29% | 100% | 
| Q29RM1 | Bos taurus | 23% | 100% | 
| Q2UCW8 | Aspergillus oryzae (strain ATCC 42149 / RIB 40) | 24% | 100% | 
| Q2YDD9 | Bos taurus | 29% | 100% | 
| Q3V132 | Mus musculus | 29% | 100% | 
| Q41629 | Triticum aestivum | 28% | 100% | 
| Q41630 | Triticum aestivum | 28% | 100% | 
| Q4QDK0 | Leishmania major | 26% | 100% | 
| Q4QIN9 | Leishmania major | 85% | 99% | 
| Q4R8M0 | Macaca fascicularis | 30% | 100% | 
| Q4X022 | Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) | 25% | 100% | 
| Q54DU1 | Dictyostelium discoideum | 24% | 100% | 
| Q54MZ4 | Dictyostelium discoideum | 27% | 83% | 
| Q5AVW1 | Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) | 24% | 100% | 
| Q5IS35 | Macaca fascicularis | 23% | 100% | 
| Q5NVC1 | Pongo abelii | 23% | 100% | 
| Q5PQ27 | Xenopus laevis | 26% | 100% | 
| Q5R5A1 | Pongo abelii | 30% | 100% | 
| Q5U3V7 | Danio rerio | 23% | 100% | 
| Q5XH95 | Xenopus tropicalis | 26% | 71% | 
| Q5XHA0 | Xenopus tropicalis | 28% | 77% | 
| Q628Z2 | Caenorhabditis briggsae | 26% | 68% | 
| Q66L49 | Danio rerio | 28% | 76% | 
| Q6DHS9 | Danio rerio | 24% | 100% | 
| Q6GQS1 | Mus musculus | 26% | 78% | 
| Q6KCM7 | Homo sapiens | 28% | 77% | 
| Q6NUK1 | Homo sapiens | 26% | 76% | 
| Q6NYZ6 | Danio rerio | 27% | 77% | 
| Q6QRN9 | Sus scrofa | 27% | 100% | 
| Q7PQV7 | Anopheles gambiae | 28% | 100% | 
| Q7S2H8 | Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) | 26% | 100% | 
| Q7T0U6 | Xenopus laevis | 28% | 77% | 
| Q7ZY36 | Xenopus laevis | 28% | 77% | 
| Q7ZYD5 | Xenopus laevis | 26% | 70% | 
| Q8BMD8 | Mus musculus | 26% | 76% | 
| Q8BVN7 | Mus musculus | 25% | 100% | 
| Q8C0K5 | Mus musculus | 23% | 100% | 
| Q8K3P6 | Rattus norvegicus | 26% | 77% | 
| Q8LB08 | Arabidopsis thaliana | 25% | 100% | 
| Q8N5S1 | Homo sapiens | 23% | 98% | 
| Q8SQH5 | Bos taurus | 29% | 100% | 
| Q8TFH2 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 25% | 100% | 
| Q8WUT9 | Homo sapiens | 23% | 100% | 
| Q9BV35 | Homo sapiens | 26% | 77% | 
| Q9DAM5 | Mus musculus | 24% | 100% | 
| Q9FI43 | Arabidopsis thaliana | 26% | 74% | 
| Q9FI73 | Arabidopsis thaliana | 23% | 100% | 
| Q9FLS8 | Arabidopsis thaliana | 26% | 76% | 
| Q9FM86 | Arabidopsis thaliana | 25% | 100% | 
| Q9H0C2 | Homo sapiens | 30% | 100% | 
| Q9HC21 | Homo sapiens | 23% | 100% | 
| Q9LY28 | Arabidopsis thaliana | 27% | 76% | 
| Q9M024 | Arabidopsis thaliana | 26% | 87% | 
| Q9SUV1 | Arabidopsis thaliana | 26% | 92% | 
| V5BTC0 | Trypanosoma cruzi | 52% | 100% | 
| V5BWX9 | Trypanosoma cruzi | 31% | 100% |