Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H4Z7_LEIBR

TriTrypDb:

LbrM.07.0530 , LBRM2903_070011700

Length:

159


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	9
GO:0110165	cellular anatomical entity	1	9

A4H4Z7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H4Z7


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	115	117	PF00082	0.350
CLV_PCSK_PC1ET2_1	115	117	PF00082	0.345
CLV_PCSK_SKI1_1	115	119	PF00082	0.226
CLV_PCSK_SKI1_1	12	16	PF00082	0.469
CLV_PCSK_SKI1_1	64	68	PF00082	0.590
CLV_PCSK_SKI1_1	7	11	PF00082	0.400
CLV_PCSK_SKI1_1	95	99	PF00082	0.343
DOC_MAPK_DCC_7	75	83	PF00069	0.288
DOC_MAPK_gen_1	100	107	PF00069	0.607
DOC_MAPK_MEF2A_6	100	107	PF00069	0.607
DOC_MAPK_MEF2A_6	75	83	PF00069	0.270
DOC_WW_Pin1_4	152	157	PF00397	0.667
LIG_Actin_WH2_2	99	117	PF00022	0.519
LIG_FHA_1	153	159	PF00498	0.715
LIG_FHA_1	49	55	PF00498	0.429
LIG_LIR_Apic_2	70	76	PF02991	0.367
LIG_LIR_Gen_1	148	157	PF02991	0.668
LIG_LIR_Gen_1	37	48	PF02991	0.530
LIG_LIR_Nem_3	148	152	PF02991	0.580
LIG_LIR_Nem_3	37	43	PF02991	0.560
LIG_PTB_Apo_2	66	73	PF02174	0.384
LIG_PTB_Phospho_1	66	72	PF10480	0.386
LIG_SH2_CRK	73	77	PF00017	0.369
LIG_SH2_STAP1	110	114	PF00017	0.517
LIG_SH2_STAT5	13	16	PF00017	0.533
LIG_SH2_STAT5	42	45	PF00017	0.318
LIG_SH3_1	73	79	PF00018	0.367
LIG_SH3_3	73	79	PF00018	0.367
LIG_SUMO_SIM_par_1	13	18	PF11976	0.604
MOD_CDK_SPxxK_3	152	159	PF00069	0.680
MOD_CK1_1	50	56	PF00069	0.365
MOD_NEK2_1	15	20	PF00069	0.629
MOD_NEK2_1	67	72	PF00069	0.430
MOD_PIKK_1	124	130	PF00454	0.594
MOD_PIKK_1	15	21	PF00454	0.584
MOD_Plk_1	15	21	PF00069	0.593
MOD_Plk_4	50	56	PF00069	0.363
MOD_Plk_4	67	73	PF00069	0.354
MOD_ProDKin_1	152	158	PF00069	0.670
MOD_SUMO_rev_2	108	117	PF00179	0.528
TRG_ER_diArg_1	99	102	PF00400	0.528


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4IUG7	Bodo saltans	64%	95%
A0A1X0NPB3	Trypanosomatidae	72%	100%
A0A3S7WPV0	Leishmania donovani	94%	100%
A4HT81	Leishmania infantum	94%	100%
C9ZUQ4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	75%	95%
E9AL59	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
Q4QIP5	Leishmania major	94%	100%
V5BYF1	Trypanosoma cruzi	71%	100%