SEC7 domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Sec7 domain containing protein, putative

Species:

Leishmania braziliensis

UniProt:

A4H4V5_LEIBR

TriTrypDb:

LbrM.07.0120 , LBRM2903_070006400

Length:

2058

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005654	nucleoplasm	2	1
GO:0005730	nucleolus	5	1
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4H4V5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term	Name	Level	Count
GO:0009966	regulation of signal transduction	4	10
GO:0010646	regulation of cell communication	4	10
GO:0023051	regulation of signaling	3	10
GO:0032012	regulation of ARF protein signal transduction	8	10
GO:0046578	regulation of Ras protein signal transduction	7	10
GO:0048583	regulation of response to stimulus	3	10
GO:0050789	regulation of biological process	2	10
GO:0050794	regulation of cellular process	3	10
GO:0051056	regulation of small GTPase mediated signal transduction	6	10
GO:0065007	biological regulation	1	10
GO:1902531	regulation of intracellular signal transduction	5	10

Molecular functions
Term	Name	Level	Count
GO:0005085	guanyl-nucleotide exchange factor activity	3	10
GO:0030234	enzyme regulator activity	2	10
GO:0030695	GTPase regulator activity	4	10
GO:0060589	nucleoside-triphosphatase regulator activity	3	10
GO:0098772	molecular function regulator activity	1	10
GO:0140677	molecular function activator activity	2	10
GO:0140678	molecular function inhibitor activity	2	10

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1227	1231	PF00656	0.448
CLV_C14_Caspase3-7	212	216	PF00656	0.579
CLV_C14_Caspase3-7	49	53	PF00656	0.549
CLV_C14_Caspase3-7	837	841	PF00656	0.444
CLV_NRD_NRD_1	1065	1067	PF00675	0.618
CLV_NRD_NRD_1	1112	1114	PF00675	0.359
CLV_NRD_NRD_1	1302	1304	PF00675	0.440
CLV_NRD_NRD_1	1397	1399	PF00675	0.547
CLV_NRD_NRD_1	1506	1508	PF00675	0.401
CLV_NRD_NRD_1	1546	1548	PF00675	0.503
CLV_NRD_NRD_1	1621	1623	PF00675	0.585
CLV_NRD_NRD_1	1699	1701	PF00675	0.374
CLV_NRD_NRD_1	175	177	PF00675	0.504
CLV_NRD_NRD_1	1806	1808	PF00675	0.622
CLV_NRD_NRD_1	1949	1951	PF00675	0.539
CLV_NRD_NRD_1	235	237	PF00675	0.519
CLV_NRD_NRD_1	735	737	PF00675	0.444
CLV_NRD_NRD_1	852	854	PF00675	0.412
CLV_PCSK_KEX2_1	1065	1067	PF00082	0.618
CLV_PCSK_KEX2_1	1112	1114	PF00082	0.359
CLV_PCSK_KEX2_1	1124	1126	PF00082	0.359
CLV_PCSK_KEX2_1	1397	1399	PF00082	0.571
CLV_PCSK_KEX2_1	1506	1508	PF00082	0.430
CLV_PCSK_KEX2_1	1546	1548	PF00082	0.503
CLV_PCSK_KEX2_1	1621	1623	PF00082	0.585
CLV_PCSK_KEX2_1	1699	1701	PF00082	0.374
CLV_PCSK_KEX2_1	175	177	PF00082	0.504
CLV_PCSK_KEX2_1	1806	1808	PF00082	0.622
CLV_PCSK_KEX2_1	1949	1951	PF00082	0.567
CLV_PCSK_KEX2_1	235	237	PF00082	0.497
CLV_PCSK_KEX2_1	467	469	PF00082	0.426
CLV_PCSK_KEX2_1	735	737	PF00082	0.444
CLV_PCSK_KEX2_1	852	854	PF00082	0.412
CLV_PCSK_KEX2_1	859	861	PF00082	0.578
CLV_PCSK_KEX2_1	887	889	PF00082	0.421
CLV_PCSK_PC1ET2_1	1124	1126	PF00082	0.383
CLV_PCSK_PC1ET2_1	467	469	PF00082	0.483
CLV_PCSK_PC1ET2_1	859	861	PF00082	0.500
CLV_PCSK_PC1ET2_1	887	889	PF00082	0.483
CLV_PCSK_SKI1_1	1004	1008	PF00082	0.434
CLV_PCSK_SKI1_1	1112	1116	PF00082	0.360
CLV_PCSK_SKI1_1	1136	1140	PF00082	0.453
CLV_PCSK_SKI1_1	1245	1249	PF00082	0.438
CLV_PCSK_SKI1_1	139	143	PF00082	0.424
CLV_PCSK_SKI1_1	1402	1406	PF00082	0.510
CLV_PCSK_SKI1_1	1547	1551	PF00082	0.461
CLV_PCSK_SKI1_1	1825	1829	PF00082	0.334
CLV_PCSK_SKI1_1	1932	1936	PF00082	0.482
CLV_PCSK_SKI1_1	377	381	PF00082	0.469
CLV_PCSK_SKI1_1	431	435	PF00082	0.308
CLV_PCSK_SKI1_1	623	627	PF00082	0.642
CLV_PCSK_SKI1_1	64	68	PF00082	0.431
CLV_PCSK_SKI1_1	904	908	PF00082	0.518
CLV_PCSK_SKI1_1	929	933	PF00082	0.404
CLV_Separin_Metazoa	1442	1446	PF03568	0.349
CLV_Separin_Metazoa	1762	1766	PF03568	0.322
CLV_Separin_Metazoa	238	242	PF03568	0.339
DEG_APCC_DBOX_1	1324	1332	PF00400	0.381
DEG_APCC_DBOX_1	138	146	PF00400	0.363
DEG_APCC_DBOX_1	1545	1553	PF00400	0.502
DEG_APCC_DBOX_1	1604	1612	PF00400	0.518
DEG_APCC_DBOX_1	186	194	PF00400	0.308
DEG_APCC_DBOX_1	622	630	PF00400	0.539
DEG_APCC_DBOX_1	851	859	PF00400	0.367
DEG_Kelch_Keap1_1	4	9	PF01344	0.405
DEG_MDM2_SWIB_1	676	684	PF02201	0.444
DEG_SCF_FBW7_2	612	619	PF00400	0.419
DEG_SPOP_SBC_1	109	113	PF00917	0.406
DEG_SPOP_SBC_1	1369	1373	PF00917	0.656
DEG_SPOP_SBC_1	27	31	PF00917	0.636
DEG_SPOP_SBC_1	37	41	PF00917	0.554
DOC_CKS1_1	15	20	PF01111	0.527
DOC_CKS1_1	1970	1975	PF01111	0.527
DOC_CKS1_1	719	724	PF01111	0.443
DOC_CYCLIN_RxL_1	61	70	PF00134	0.476
DOC_CYCLIN_RxL_1	732	743	PF00134	0.442
DOC_CYCLIN_yCln2_LP_2	1499	1505	PF00134	0.241
DOC_CYCLIN_yCln2_LP_2	594	600	PF00134	0.500
DOC_CYCLIN_yCln2_LP_2	684	687	PF00134	0.444
DOC_MAPK_DCC_7	1546	1554	PF00069	0.490
DOC_MAPK_gen_1	1124	1132	PF00069	0.495
DOC_MAPK_gen_1	1215	1225	PF00069	0.414
DOC_MAPK_gen_1	1445	1454	PF00069	0.498
DOC_MAPK_gen_1	1546	1554	PF00069	0.501
DOC_MAPK_gen_1	467	474	PF00069	0.504
DOC_MAPK_MEF2A_6	1445	1454	PF00069	0.537
DOC_MAPK_MEF2A_6	1546	1554	PF00069	0.363
DOC_MAPK_MEF2A_6	161	170	PF00069	0.428
DOC_MAPK_MEF2A_6	1765	1774	PF00069	0.545
DOC_MAPK_MEF2A_6	467	474	PF00069	0.519
DOC_MAPK_MEF2A_6	491	500	PF00069	0.397
DOC_MAPK_MEF2A_6	792	801	PF00069	0.444
DOC_MAPK_MEF2A_6	82	89	PF00069	0.460
DOC_MAPK_NFAT4_5	467	475	PF00069	0.517
DOC_MAPK_NFAT4_5	491	499	PF00069	0.288
DOC_MAPK_RevD_3	1109	1125	PF00069	0.249
DOC_PP1_RVXF_1	62	68	PF00149	0.477
DOC_PP1_RVXF_1	886	893	PF00149	0.433
DOC_PP2B_LxvP_1	1499	1502	PF13499	0.240
DOC_PP2B_LxvP_1	1940	1943	PF13499	0.375
DOC_PP2B_LxvP_1	594	597	PF13499	0.514
DOC_PP2B_LxvP_1	684	687	PF13499	0.444
DOC_PP2B_PxIxI_1	1384	1390	PF00149	0.414
DOC_PP4_FxxP_1	1497	1500	PF00568	0.457
DOC_PP4_FxxP_1	1553	1556	PF00568	0.346
DOC_PP4_FxxP_1	582	585	PF00568	0.402
DOC_PP4_FxxP_1	976	979	PF00568	0.499
DOC_USP7_MATH_1	1068	1072	PF00917	0.634
DOC_USP7_MATH_1	1226	1230	PF00917	0.475
DOC_USP7_MATH_1	1369	1373	PF00917	0.636
DOC_USP7_MATH_1	152	156	PF00917	0.342
DOC_USP7_MATH_1	1540	1544	PF00917	0.479
DOC_USP7_MATH_1	1556	1560	PF00917	0.262
DOC_USP7_MATH_1	1566	1570	PF00917	0.383
DOC_USP7_MATH_1	1614	1618	PF00917	0.428
DOC_USP7_MATH_1	1627	1631	PF00917	0.510
DOC_USP7_MATH_1	1687	1691	PF00917	0.608
DOC_USP7_MATH_1	1740	1744	PF00917	0.649
DOC_USP7_MATH_1	1746	1750	PF00917	0.667
DOC_USP7_MATH_1	1754	1758	PF00917	0.575
DOC_USP7_MATH_1	1764	1768	PF00917	0.463
DOC_USP7_MATH_1	1799	1803	PF00917	0.655
DOC_USP7_MATH_1	1872	1876	PF00917	0.631
DOC_USP7_MATH_1	2012	2016	PF00917	0.629
DOC_USP7_MATH_1	3	7	PF00917	0.629
DOC_USP7_MATH_1	37	41	PF00917	0.575
DOC_USP7_MATH_1	487	491	PF00917	0.340
DOC_USP7_MATH_1	554	558	PF00917	0.558
DOC_USP7_MATH_1	578	582	PF00917	0.643
DOC_USP7_MATH_1	687	691	PF00917	0.444
DOC_USP7_MATH_1	740	744	PF00917	0.437
DOC_USP7_MATH_1	790	794	PF00917	0.401
DOC_USP7_MATH_1	854	858	PF00917	0.481
DOC_USP7_MATH_1	865	869	PF00917	0.545
DOC_USP7_MATH_2	578	584	PF00917	0.429
DOC_USP7_MATH_2	616	622	PF00917	0.658
DOC_USP7_UBL2_3	654	658	PF12436	0.344
DOC_WW_Pin1_4	1	6	PF00397	0.609
DOC_WW_Pin1_4	1371	1376	PF00397	0.635
DOC_WW_Pin1_4	1381	1386	PF00397	0.565
DOC_WW_Pin1_4	14	19	PF00397	0.491
DOC_WW_Pin1_4	1481	1486	PF00397	0.495
DOC_WW_Pin1_4	1489	1494	PF00397	0.374
DOC_WW_Pin1_4	1552	1557	PF00397	0.348
DOC_WW_Pin1_4	1610	1615	PF00397	0.539
DOC_WW_Pin1_4	1867	1872	PF00397	0.659
DOC_WW_Pin1_4	1902	1907	PF00397	0.418
DOC_WW_Pin1_4	1969	1974	PF00397	0.489
DOC_WW_Pin1_4	323	328	PF00397	0.601
DOC_WW_Pin1_4	331	336	PF00397	0.568
DOC_WW_Pin1_4	456	461	PF00397	0.390
DOC_WW_Pin1_4	574	579	PF00397	0.653
DOC_WW_Pin1_4	581	586	PF00397	0.436
DOC_WW_Pin1_4	612	617	PF00397	0.665
DOC_WW_Pin1_4	648	653	PF00397	0.250
DOC_WW_Pin1_4	718	723	PF00397	0.416
DOC_WW_Pin1_4	993	998	PF00397	0.506
LIG_14-3-3_CanoR_1	1034	1042	PF00244	0.527
LIG_14-3-3_CanoR_1	1057	1061	PF00244	0.469
LIG_14-3-3_CanoR_1	1182	1188	PF00244	0.331
LIG_14-3-3_CanoR_1	1325	1329	PF00244	0.245
LIG_14-3-3_CanoR_1	1402	1410	PF00244	0.621
LIG_14-3-3_CanoR_1	1445	1451	PF00244	0.541
LIG_14-3-3_CanoR_1	1507	1517	PF00244	0.399
LIG_14-3-3_CanoR_1	1568	1576	PF00244	0.424
LIG_14-3-3_CanoR_1	1605	1614	PF00244	0.525
LIG_14-3-3_CanoR_1	1765	1772	PF00244	0.552
LIG_14-3-3_CanoR_1	377	386	PF00244	0.489
LIG_14-3-3_CanoR_1	431	441	PF00244	0.331
LIG_14-3-3_CanoR_1	898	907	PF00244	0.446
LIG_14-3-3_CanoR_1	91	100	PF00244	0.417
LIG_14-3-3_CanoR_1	964	970	PF00244	0.387
LIG_Actin_WH2_1	1440	1457	PF00022	0.314
LIG_Actin_WH2_2	1097	1114	PF00022	0.464
LIG_AP2alpha_1	838	842	PF02296	0.424
LIG_BIR_II_1	1	5	PF00653	0.436
LIG_BIR_III_2	994	998	PF00653	0.504
LIG_BRCT_BRCA1_1	123	127	PF00533	0.499
LIG_BRCT_BRCA1_1	158	162	PF00533	0.429
LIG_BRCT_BRCA1_1	261	265	PF00533	0.540
LIG_BRCT_BRCA1_1	578	582	PF00533	0.638
LIG_deltaCOP1_diTrp_1	921	931	PF00928	0.518
LIG_eIF4E_1	1841	1847	PF01652	0.579
LIG_EVH1_1	685	689	PF00568	0.233
LIG_FHA_1	1011	1017	PF00498	0.478
LIG_FHA_1	1043	1049	PF00498	0.305
LIG_FHA_1	1077	1083	PF00498	0.565
LIG_FHA_1	1116	1122	PF00498	0.431
LIG_FHA_1	1124	1130	PF00498	0.407
LIG_FHA_1	1137	1143	PF00498	0.456
LIG_FHA_1	1178	1184	PF00498	0.442
LIG_FHA_1	1196	1202	PF00498	0.561
LIG_FHA_1	1358	1364	PF00498	0.369
LIG_FHA_1	136	142	PF00498	0.390
LIG_FHA_1	1404	1410	PF00498	0.557
LIG_FHA_1	1447	1453	PF00498	0.474
LIG_FHA_1	1481	1487	PF00498	0.480
LIG_FHA_1	1490	1496	PF00498	0.240
LIG_FHA_1	1643	1649	PF00498	0.506
LIG_FHA_1	1673	1679	PF00498	0.573
LIG_FHA_1	1848	1854	PF00498	0.554
LIG_FHA_1	1896	1902	PF00498	0.497
LIG_FHA_1	1939	1945	PF00498	0.428
LIG_FHA_1	1975	1981	PF00498	0.389
LIG_FHA_1	1985	1991	PF00498	0.351
LIG_FHA_1	29	35	PF00498	0.595
LIG_FHA_1	315	321	PF00498	0.491
LIG_FHA_1	374	380	PF00498	0.512
LIG_FHA_1	39	45	PF00498	0.624
LIG_FHA_1	467	473	PF00498	0.536
LIG_FHA_1	518	524	PF00498	0.488
LIG_FHA_1	558	564	PF00498	0.386
LIG_FHA_1	719	725	PF00498	0.391
LIG_FHA_1	802	808	PF00498	0.401
LIG_FHA_1	901	907	PF00498	0.480
LIG_FHA_1	981	987	PF00498	0.469
LIG_FHA_2	1048	1054	PF00498	0.504
LIG_FHA_2	110	116	PF00498	0.636
LIG_FHA_2	1256	1262	PF00498	0.292
LIG_FHA_2	1288	1294	PF00498	0.411
LIG_FHA_2	1437	1443	PF00498	0.442
LIG_FHA_2	1537	1543	PF00498	0.416
LIG_FHA_2	1979	1985	PF00498	0.427
LIG_FHA_2	434	440	PF00498	0.286
LIG_FHA_2	559	565	PF00498	0.392
LIG_FHA_2	575	581	PF00498	0.714
LIG_FHA_2	613	619	PF00498	0.675
LIG_FHA_2	631	637	PF00498	0.338
LIG_FHA_2	718	724	PF00498	0.485
LIG_FHA_2	909	915	PF00498	0.608
LIG_GBD_Chelix_1	1524	1532	PF00786	0.516
LIG_GBD_Chelix_1	374	382	PF00786	0.554
LIG_HP1_1	280	284	PF01393	0.607
LIG_Integrin_isoDGR_2	2046	2048	PF01839	0.387
LIG_LIR_Apic_2	1758	1764	PF02991	0.491
LIG_LIR_Apic_2	579	585	PF02991	0.419
LIG_LIR_Gen_1	1046	1055	PF02991	0.484
LIG_LIR_Gen_1	1116	1123	PF02991	0.387
LIG_LIR_Gen_1	1137	1146	PF02991	0.412
LIG_LIR_Gen_1	124	134	PF02991	0.475
LIG_LIR_Gen_1	1265	1271	PF02991	0.514
LIG_LIR_Gen_1	1272	1281	PF02991	0.385
LIG_LIR_Gen_1	1492	1502	PF02991	0.306
LIG_LIR_Gen_1	1714	1723	PF02991	0.427
LIG_LIR_Gen_1	1781	1789	PF02991	0.494
LIG_LIR_Gen_1	1917	1927	PF02991	0.474
LIG_LIR_Gen_1	61	67	PF02991	0.440
LIG_LIR_Gen_1	795	806	PF02991	0.396
LIG_LIR_Gen_1	876	882	PF02991	0.552
LIG_LIR_Gen_1	934	943	PF02991	0.346
LIG_LIR_Nem_3	1046	1052	PF02991	0.468
LIG_LIR_Nem_3	1116	1120	PF02991	0.413
LIG_LIR_Nem_3	1137	1141	PF02991	0.400
LIG_LIR_Nem_3	1173	1178	PF02991	0.418
LIG_LIR_Nem_3	1213	1217	PF02991	0.457
LIG_LIR_Nem_3	124	130	PF02991	0.485
LIG_LIR_Nem_3	1272	1276	PF02991	0.398
LIG_LIR_Nem_3	1492	1497	PF02991	0.286
LIG_LIR_Nem_3	1633	1638	PF02991	0.469
LIG_LIR_Nem_3	1668	1673	PF02991	0.365
LIG_LIR_Nem_3	1714	1718	PF02991	0.420
LIG_LIR_Nem_3	1781	1786	PF02991	0.449
LIG_LIR_Nem_3	1917	1923	PF02991	0.484
LIG_LIR_Nem_3	1984	1989	PF02991	0.428
LIG_LIR_Nem_3	401	407	PF02991	0.317
LIG_LIR_Nem_3	61	65	PF02991	0.440
LIG_LIR_Nem_3	795	801	PF02991	0.396
LIG_LIR_Nem_3	844	850	PF02991	0.369
LIG_LIR_Nem_3	876	880	PF02991	0.538
LIG_LIR_Nem_3	921	927	PF02991	0.486
LIG_LIR_Nem_3	934	939	PF02991	0.221
LIG_MYND_1	24	28	PF01753	0.416
LIG_NRBOX	1166	1172	PF00104	0.471
LIG_NRBOX	1327	1333	PF00104	0.352
LIG_NRBOX	1427	1433	PF00104	0.431
LIG_NRBOX	1929	1935	PF00104	0.431
LIG_NRBOX	1966	1972	PF00104	0.422
LIG_NRBOX	83	89	PF00104	0.457
LIG_NRBOX	965	971	PF00104	0.452
LIG_NRBOX	985	991	PF00104	0.198
LIG_Pex14_1	1023	1027	PF04695	0.235
LIG_Pex14_2	1210	1214	PF04695	0.415
LIG_Pex14_2	1509	1513	PF04695	0.265
LIG_Pex14_2	1783	1787	PF04695	0.426
LIG_Pex14_2	474	478	PF04695	0.512
LIG_Pex14_2	676	680	PF04695	0.444
LIG_Pex14_2	838	842	PF04695	0.344
LIG_Pex14_2	877	881	PF04695	0.522
LIG_PTB_Apo_2	1413	1420	PF02174	0.508
LIG_PTB_Phospho_1	1413	1419	PF10480	0.512
LIG_Rb_pABgroove_1	498	506	PF01858	0.429
LIG_Rb_pABgroove_1	61	69	PF01858	0.476
LIG_SH2_CRK	1027	1031	PF00017	0.236
LIG_SH2_CRK	1117	1121	PF00017	0.388
LIG_SH2_CRK	1920	1924	PF00017	0.461
LIG_SH2_CRK	404	408	PF00017	0.485
LIG_SH2_CRK	449	453	PF00017	0.467
LIG_SH2_GRB2like	1715	1718	PF00017	0.505
LIG_SH2_GRB2like	449	452	PF00017	0.424
LIG_SH2_PTP2	1146	1149	PF00017	0.504
LIG_SH2_PTP2	1715	1718	PF00017	0.505
LIG_SH2_STAP1	1014	1018	PF00017	0.448
LIG_SH2_STAP1	1117	1121	PF00017	0.463
LIG_SH2_STAP1	1221	1225	PF00017	0.465
LIG_SH2_STAP1	1267	1271	PF00017	0.468
LIG_SH2_STAP1	1602	1606	PF00017	0.440
LIG_SH2_STAP1	1644	1648	PF00017	0.414
LIG_SH2_STAP1	449	453	PF00017	0.424
LIG_SH2_STAP1	504	508	PF00017	0.505
LIG_SH2_STAT3	1638	1641	PF00017	0.516
LIG_SH2_STAT3	1798	1801	PF00017	0.613
LIG_SH2_STAT5	1117	1120	PF00017	0.419
LIG_SH2_STAT5	1131	1134	PF00017	0.341
LIG_SH2_STAT5	1146	1149	PF00017	0.504
LIG_SH2_STAT5	1267	1270	PF00017	0.471
LIG_SH2_STAT5	1419	1422	PF00017	0.481
LIG_SH2_STAT5	1638	1641	PF00017	0.475
LIG_SH2_STAT5	1644	1647	PF00017	0.484
LIG_SH2_STAT5	1715	1718	PF00017	0.421
LIG_SH2_STAT5	180	183	PF00017	0.550
LIG_SH2_STAT5	1831	1834	PF00017	0.436
LIG_SH2_STAT5	1929	1932	PF00017	0.470
LIG_SH2_STAT5	1985	1988	PF00017	0.371
LIG_SH2_STAT5	1989	1992	PF00017	0.386
LIG_SH2_STAT5	357	360	PF00017	0.400
LIG_SH2_STAT5	465	468	PF00017	0.508
LIG_SH2_STAT5	62	65	PF00017	0.477
LIG_SH2_STAT5	733	736	PF00017	0.444
LIG_SH2_STAT5	770	773	PF00017	0.410
LIG_SH3_3	1138	1144	PF00018	0.501
LIG_SH3_3	1182	1188	PF00018	0.545
LIG_SH3_3	12	18	PF00018	0.503
LIG_SH3_3	1273	1279	PF00018	0.414
LIG_SH3_3	1376	1382	PF00018	0.678
LIG_SH3_3	1386	1392	PF00018	0.522
LIG_SH3_3	1573	1579	PF00018	0.463
LIG_SH3_3	1601	1607	PF00018	0.502
LIG_SH3_3	1608	1614	PF00018	0.415
LIG_SH3_3	1866	1872	PF00018	0.667
LIG_SH3_3	2026	2032	PF00018	0.411
LIG_SH3_3	255	261	PF00018	0.512
LIG_SH3_3	457	463	PF00018	0.383
LIG_SH3_3	683	689	PF00018	0.258
LIG_SH3_3	752	758	PF00018	0.369
LIG_SH3_3	912	918	PF00018	0.553
LIG_SH3_3	939	945	PF00018	0.455
LIG_Sin3_3	1138	1145	PF02671	0.466
LIG_SUMO_SIM_anti_2	11	17	PF11976	0.615
LIG_SUMO_SIM_anti_2	1105	1112	PF11976	0.503
LIG_SUMO_SIM_anti_2	1165	1173	PF11976	0.368
LIG_SUMO_SIM_anti_2	1296	1301	PF11976	0.457
LIG_SUMO_SIM_anti_2	1966	1972	PF11976	0.498
LIG_SUMO_SIM_anti_2	983	988	PF11976	0.478
LIG_SUMO_SIM_par_1	1196	1205	PF11976	0.552
LIG_SUMO_SIM_par_1	1384	1391	PF11976	0.411
LIG_SUMO_SIM_par_1	1462	1468	PF11976	0.264
LIG_SUMO_SIM_par_1	1845	1852	PF11976	0.527
LIG_SUMO_SIM_par_1	1966	1972	PF11976	0.483
LIG_SUMO_SIM_par_1	1976	1981	PF11976	0.370
LIG_SUMO_SIM_par_1	55	61	PF11976	0.372
LIG_SUMO_SIM_par_1	798	804	PF11976	0.356
LIG_SUMO_SIM_par_1	930	938	PF11976	0.236
LIG_SUMO_SIM_par_1	980	988	PF11976	0.470
LIG_SxIP_EBH_1	491	500	PF03271	0.286
LIG_TRAF2_1	113	116	PF00917	0.624
LIG_TRAF2_1	1272	1275	PF00917	0.494
LIG_TRAF2_1	1412	1415	PF00917	0.531
LIG_TRAF2_1	1674	1677	PF00917	0.627
LIG_TRAF2_1	1694	1697	PF00917	0.582
LIG_TRAF2_1	1905	1908	PF00917	0.625
LIG_TRAF2_1	322	325	PF00917	0.404
LIG_TRAF2_1	531	534	PF00917	0.556
LIG_TRAF2_1	616	619	PF00917	0.644
LIG_TRAF2_1	663	666	PF00917	0.424
LIG_TRAF2_1	883	886	PF00917	0.426
LIG_TYR_ITIM	1115	1120	PF00017	0.387
LIG_TYR_ITIM	1713	1718	PF00017	0.419
LIG_TYR_ITIM	60	65	PF00017	0.474
LIG_UBA3_1	126	132	PF00899	0.513
LIG_UBA3_1	1299	1304	PF00899	0.453
LIG_Vh1_VBS_1	89	107	PF01044	0.477
LIG_WRC_WIRS_1	1211	1216	PF05994	0.362
LIG_WRC_WIRS_1	1667	1672	PF05994	0.363
LIG_WRC_WIRS_1	475	480	PF05994	0.419
LIG_WW_2	686	689	PF00397	0.233
MOD_CDC14_SPxK_1	1870	1873	PF00782	0.449
MOD_CDC14_SPxK_1	651	654	PF00782	0.250
MOD_CDK_SPK_2	648	653	PF00069	0.339
MOD_CDK_SPxK_1	1867	1873	PF00069	0.444
MOD_CDK_SPxK_1	648	654	PF00069	0.250
MOD_CDK_SPxK_1	993	999	PF00069	0.506
MOD_CK1_1	1177	1183	PF00069	0.476
MOD_CK1_1	1229	1235	PF00069	0.393
MOD_CK1_1	1265	1271	PF00069	0.456
MOD_CK1_1	1357	1363	PF00069	0.403
MOD_CK1_1	1371	1377	PF00069	0.550
MOD_CK1_1	14	20	PF00069	0.504
MOD_CK1_1	1489	1495	PF00069	0.463
MOD_CK1_1	151	157	PF00069	0.366
MOD_CK1_1	1512	1518	PF00069	0.463
MOD_CK1_1	1555	1561	PF00069	0.399
MOD_CK1_1	1613	1619	PF00069	0.568
MOD_CK1_1	1630	1636	PF00069	0.216
MOD_CK1_1	1736	1742	PF00069	0.429
MOD_CK1_1	1966	1972	PF00069	0.452
MOD_CK1_1	199	205	PF00069	0.488
MOD_CK1_1	2000	2006	PF00069	0.504
MOD_CK1_1	314	320	PF00069	0.589
MOD_CK1_1	329	335	PF00069	0.448
MOD_CK1_1	351	357	PF00069	0.464
MOD_CK1_1	38	44	PF00069	0.556
MOD_CK1_1	4	10	PF00069	0.509
MOD_CK1_1	459	465	PF00069	0.387
MOD_CK1_1	483	489	PF00069	0.461
MOD_CK1_1	521	527	PF00069	0.557
MOD_CK1_1	557	563	PF00069	0.531
MOD_CK1_1	581	587	PF00069	0.574
MOD_CK1_1	690	696	PF00069	0.339
MOD_CK1_1	873	879	PF00069	0.515
MOD_CK1_1	934	940	PF00069	0.447
MOD_CK1_1	953	959	PF00069	0.276
MOD_CK2_1	1047	1053	PF00069	0.491
MOD_CK2_1	109	115	PF00069	0.661
MOD_CK2_1	1216	1222	PF00069	0.473
MOD_CK2_1	1269	1275	PF00069	0.482
MOD_CK2_1	1287	1293	PF00069	0.258
MOD_CK2_1	1409	1415	PF00069	0.555
MOD_CK2_1	1436	1442	PF00069	0.432
MOD_CK2_1	1536	1542	PF00069	0.424
MOD_CK2_1	1746	1752	PF00069	0.428
MOD_CK2_1	180	186	PF00069	0.546
MOD_CK2_1	1902	1908	PF00069	0.431
MOD_CK2_1	291	297	PF00069	0.585
MOD_CK2_1	3	9	PF00069	0.543
MOD_CK2_1	433	439	PF00069	0.403
MOD_CK2_1	574	580	PF00069	0.698
MOD_CK2_1	612	618	PF00069	0.651
MOD_CK2_1	630	636	PF00069	0.466
MOD_CK2_1	660	666	PF00069	0.421
MOD_CK2_1	675	681	PF00069	0.474
MOD_CK2_1	717	723	PF00069	0.425
MOD_CK2_1	740	746	PF00069	0.444
MOD_CK2_1	880	886	PF00069	0.408
MOD_Cter_Amidation	1063	1066	PF01082	0.381
MOD_Cter_Amidation	1619	1622	PF01082	0.577
MOD_GlcNHglycan	1093	1096	PF01048	0.463
MOD_GlcNHglycan	1105	1108	PF01048	0.391
MOD_GlcNHglycan	1185	1188	PF01048	0.470
MOD_GlcNHglycan	1226	1229	PF01048	0.441
MOD_GlcNHglycan	123	126	PF01048	0.537
MOD_GlcNHglycan	1230	1234	PF01048	0.419
MOD_GlcNHglycan	1258	1261	PF01048	0.429
MOD_GlcNHglycan	1346	1349	PF01048	0.394
MOD_GlcNHglycan	1365	1368	PF01048	0.320
MOD_GlcNHglycan	150	153	PF01048	0.446
MOD_GlcNHglycan	1532	1535	PF01048	0.499
MOD_GlcNHglycan	1629	1632	PF01048	0.531
MOD_GlcNHglycan	1735	1738	PF01048	0.602
MOD_GlcNHglycan	1746	1749	PF01048	0.607
MOD_GlcNHglycan	1766	1769	PF01048	0.227
MOD_GlcNHglycan	18	21	PF01048	0.606
MOD_GlcNHglycan	1815	1818	PF01048	0.534
MOD_GlcNHglycan	1842	1845	PF01048	0.579
MOD_GlcNHglycan	1916	1919	PF01048	0.480
MOD_GlcNHglycan	199	202	PF01048	0.480
MOD_GlcNHglycan	1999	2002	PF01048	0.574
MOD_GlcNHglycan	2010	2013	PF01048	0.605
MOD_GlcNHglycan	2014	2017	PF01048	0.635
MOD_GlcNHglycan	2021	2024	PF01048	0.427
MOD_GlcNHglycan	2032	2035	PF01048	0.352
MOD_GlcNHglycan	328	331	PF01048	0.616
MOD_GlcNHglycan	353	356	PF01048	0.503
MOD_GlcNHglycan	485	488	PF01048	0.516
MOD_GlcNHglycan	491	494	PF01048	0.246
MOD_GlcNHglycan	520	523	PF01048	0.504
MOD_GlcNHglycan	556	559	PF01048	0.568
MOD_GlcNHglycan	618	623	PF01048	0.671
MOD_GlcNHglycan	662	665	PF01048	0.452
MOD_GlcNHglycan	689	692	PF01048	0.495
MOD_GlcNHglycan	771	774	PF01048	0.361
MOD_GlcNHglycan	814	817	PF01048	0.485
MOD_GlcNHglycan	952	955	PF01048	0.494
MOD_GSK3_1	1033	1040	PF00069	0.381
MOD_GSK3_1	104	111	PF00069	0.541
MOD_GSK3_1	1068	1075	PF00069	0.620
MOD_GSK3_1	1170	1177	PF00069	0.378
MOD_GSK3_1	1183	1190	PF00069	0.489
MOD_GSK3_1	1195	1202	PF00069	0.387
MOD_GSK3_1	1265	1272	PF00069	0.496
MOD_GSK3_1	1309	1316	PF00069	0.467
MOD_GSK3_1	1353	1360	PF00069	0.391
MOD_GSK3_1	1365	1372	PF00069	0.480
MOD_GSK3_1	148	155	PF00069	0.413
MOD_GSK3_1	1480	1487	PF00069	0.349
MOD_GSK3_1	1508	1515	PF00069	0.430
MOD_GSK3_1	1536	1543	PF00069	0.510
MOD_GSK3_1	1552	1559	PF00069	0.243
MOD_GSK3_1	1606	1613	PF00069	0.496
MOD_GSK3_1	1626	1633	PF00069	0.491
MOD_GSK3_1	1681	1688	PF00069	0.532
MOD_GSK3_1	1701	1708	PF00069	0.433
MOD_GSK3_1	1732	1739	PF00069	0.540
MOD_GSK3_1	1740	1747	PF00069	0.601
MOD_GSK3_1	1836	1843	PF00069	0.512
MOD_GSK3_1	1879	1886	PF00069	0.596
MOD_GSK3_1	1932	1939	PF00069	0.442
MOD_GSK3_1	1974	1981	PF00069	0.359
MOD_GSK3_1	2008	2015	PF00069	0.631
MOD_GSK3_1	2030	2037	PF00069	0.625
MOD_GSK3_1	244	251	PF00069	0.477
MOD_GSK3_1	298	305	PF00069	0.447
MOD_GSK3_1	309	316	PF00069	0.553
MOD_GSK3_1	344	351	PF00069	0.300
MOD_GSK3_1	373	380	PF00069	0.558
MOD_GSK3_1	38	45	PF00069	0.564
MOD_GSK3_1	479	486	PF00069	0.473
MOD_GSK3_1	517	524	PF00069	0.466
MOD_GSK3_1	554	561	PF00069	0.522
MOD_GSK3_1	574	581	PF00069	0.652
MOD_GSK3_1	630	637	PF00069	0.636
MOD_GSK3_1	702	709	PF00069	0.384
MOD_GSK3_1	866	873	PF00069	0.481
MOD_GSK3_1	92	99	PF00069	0.425
MOD_GSK3_1	931	938	PF00069	0.393
MOD_GSK3_1	949	956	PF00069	0.309
MOD_GSK3_1	965	972	PF00069	0.349
MOD_N-GLC_1	1102	1107	PF02516	0.462
MOD_N-GLC_1	1556	1561	PF02516	0.238
MOD_N-GLC_1	2039	2044	PF02516	0.662
MOD_N-GLC_1	480	485	PF02516	0.302
MOD_N-GLC_1	573	578	PF02516	0.713
MOD_N-GLC_1	648	653	PF02516	0.316
MOD_NEK2_1	1115	1120	PF00069	0.363
MOD_NEK2_1	1163	1168	PF00069	0.484
MOD_NEK2_1	1170	1175	PF00069	0.458
MOD_NEK2_1	1210	1215	PF00069	0.501
MOD_NEK2_1	1248	1253	PF00069	0.445
MOD_NEK2_1	1269	1274	PF00069	0.453
MOD_NEK2_1	1354	1359	PF00069	0.420
MOD_NEK2_1	1365	1370	PF00069	0.464
MOD_NEK2_1	1471	1476	PF00069	0.440
MOD_NEK2_1	1509	1514	PF00069	0.379
MOD_NEK2_1	1772	1777	PF00069	0.366
MOD_NEK2_1	196	201	PF00069	0.478
MOD_NEK2_1	1963	1968	PF00069	0.457
MOD_NEK2_1	1978	1983	PF00069	0.295
MOD_NEK2_1	248	253	PF00069	0.483
MOD_NEK2_1	265	270	PF00069	0.338
MOD_NEK2_1	311	316	PF00069	0.596
MOD_NEK2_1	349	354	PF00069	0.415
MOD_NEK2_1	373	378	PF00069	0.462
MOD_NEK2_1	398	403	PF00069	0.323
MOD_NEK2_1	432	437	PF00069	0.541
MOD_NEK2_1	447	452	PF00069	0.253
MOD_NEK2_1	474	479	PF00069	0.353
MOD_NEK2_1	563	568	PF00069	0.657
MOD_NEK2_1	610	615	PF00069	0.562
MOD_NEK2_1	80	85	PF00069	0.509
MOD_NEK2_1	806	811	PF00069	0.369
MOD_NEK2_1	931	936	PF00069	0.391
MOD_NEK2_1	969	974	PF00069	0.296
MOD_NEK2_2	1216	1221	PF00069	0.350
MOD_NEK2_2	1778	1783	PF00069	0.504
MOD_NEK2_2	630	635	PF00069	0.634
MOD_NEK2_2	854	859	PF00069	0.489
MOD_PIKK_1	1403	1409	PF00454	0.580
MOD_PIKK_1	1568	1574	PF00454	0.453
MOD_PIKK_1	1681	1687	PF00454	0.406
MOD_PIKK_1	533	539	PF00454	0.469
MOD_PIKK_1	558	564	PF00454	0.594
MOD_PIKK_1	610	616	PF00454	0.613
MOD_PIKK_1	675	681	PF00454	0.457
MOD_PIKK_1	702	708	PF00454	0.358
MOD_PIKK_1	880	886	PF00454	0.483
MOD_PIKK_1	908	914	PF00454	0.592
MOD_PK_1	658	664	PF00069	0.233
MOD_PKA_2	1033	1039	PF00069	0.515
MOD_PKA_2	1056	1062	PF00069	0.469
MOD_PKA_2	1076	1082	PF00069	0.573
MOD_PKA_2	1181	1187	PF00069	0.317
MOD_PKA_2	1286	1292	PF00069	0.470
MOD_PKA_2	1324	1330	PF00069	0.246
MOD_PKA_2	1509	1515	PF00069	0.400
MOD_PKA_2	1698	1704	PF00069	0.485
MOD_PKA_2	1764	1770	PF00069	0.559
MOD_PKA_2	1813	1819	PF00069	0.628
MOD_PKA_2	2008	2014	PF00069	0.389
MOD_PKA_2	634	640	PF00069	0.644
MOD_PKA_2	848	854	PF00069	0.418
MOD_PKA_2	873	879	PF00069	0.534
MOD_Plk_1	1068	1074	PF00069	0.483
MOD_Plk_1	1115	1121	PF00069	0.462
MOD_Plk_1	1136	1142	PF00069	0.454
MOD_Plk_1	1221	1227	PF00069	0.432
MOD_Plk_1	1556	1562	PF00069	0.239
MOD_Plk_1	1614	1620	PF00069	0.579
MOD_Plk_1	1890	1896	PF00069	0.622
MOD_Plk_1	207	213	PF00069	0.361
MOD_Plk_1	480	486	PF00069	0.307
MOD_Plk_1	680	686	PF00069	0.401
MOD_Plk_1	834	840	PF00069	0.429
MOD_Plk_1	980	986	PF00069	0.465
MOD_Plk_2-3	291	297	PF00069	0.569
MOD_Plk_2-3	834	840	PF00069	0.424
MOD_Plk_4	1163	1169	PF00069	0.384
MOD_Plk_4	1170	1176	PF00069	0.381
MOD_Plk_4	1231	1237	PF00069	0.414
MOD_Plk_4	1262	1268	PF00069	0.466
MOD_Plk_4	1324	1330	PF00069	0.367
MOD_Plk_4	1516	1522	PF00069	0.298
MOD_Plk_4	1540	1546	PF00069	0.481
MOD_Plk_4	1614	1620	PF00069	0.467
MOD_Plk_4	1778	1784	PF00069	0.389
MOD_Plk_4	1963	1969	PF00069	0.433
MOD_Plk_4	1974	1980	PF00069	0.340
MOD_Plk_4	2034	2040	PF00069	0.439
MOD_Plk_4	244	250	PF00069	0.543
MOD_Plk_4	474	480	PF00069	0.405
MOD_Plk_4	58	64	PF00069	0.443
MOD_Plk_4	680	686	PF00069	0.444
MOD_Plk_4	740	746	PF00069	0.407
MOD_Plk_4	80	86	PF00069	0.475
MOD_Plk_4	801	807	PF00069	0.401
MOD_Plk_4	92	98	PF00069	0.341
MOD_Plk_4	931	937	PF00069	0.236
MOD_Plk_4	965	971	PF00069	0.392
MOD_Plk_4	982	988	PF00069	0.293
MOD_ProDKin_1	1	7	PF00069	0.439
MOD_ProDKin_1	1371	1377	PF00069	0.634
MOD_ProDKin_1	1381	1387	PF00069	0.560
MOD_ProDKin_1	14	20	PF00069	0.487
MOD_ProDKin_1	1481	1487	PF00069	0.489
MOD_ProDKin_1	1489	1495	PF00069	0.372
MOD_ProDKin_1	1552	1558	PF00069	0.348
MOD_ProDKin_1	1610	1616	PF00069	0.543
MOD_ProDKin_1	1867	1873	PF00069	0.661
MOD_ProDKin_1	1902	1908	PF00069	0.418
MOD_ProDKin_1	1969	1975	PF00069	0.488
MOD_ProDKin_1	323	329	PF00069	0.599
MOD_ProDKin_1	331	337	PF00069	0.566
MOD_ProDKin_1	456	462	PF00069	0.391
MOD_ProDKin_1	574	580	PF00069	0.647
MOD_ProDKin_1	581	587	PF00069	0.433
MOD_ProDKin_1	612	618	PF00069	0.668
MOD_ProDKin_1	648	654	PF00069	0.250
MOD_ProDKin_1	718	724	PF00069	0.416
MOD_ProDKin_1	993	999	PF00069	0.506
MOD_SUMO_for_1	531	534	PF00179	0.597
MOD_SUMO_rev_2	2051	2058	PF00179	0.387
MOD_SUMO_rev_2	815	825	PF00179	0.447
TRG_DiLeu_BaEn_1	1653	1658	PF01217	0.607
TRG_DiLeu_BaEn_1	1714	1719	PF01217	0.421
TRG_DiLeu_BaEn_1	902	907	PF01217	0.508
TRG_DiLeu_BaEn_4	188	194	PF01217	0.521
TRG_DiLeu_BaEn_4	885	891	PF01217	0.448
TRG_DiLeu_BaLyEn_6	1929	1934	PF01217	0.514
TRG_DiLeu_BaLyEn_6	374	379	PF01217	0.444
TRG_DiLeu_BaLyEn_6	389	394	PF01217	0.399
TRG_DiLeu_BaLyEn_6	428	433	PF01217	0.274
TRG_DiLeu_BaLyEn_6	452	457	PF01217	0.515
TRG_DiLeu_BaLyEn_6	61	66	PF01217	0.476
TRG_DiLeu_BaLyEn_6	763	768	PF01217	0.344
TRG_DiLeu_BaLyEn_6	83	88	PF01217	0.446
TRG_ENDOCYTIC_2	1027	1030	PF00928	0.236
TRG_ENDOCYTIC_2	1117	1120	PF00928	0.389
TRG_ENDOCYTIC_2	1146	1149	PF00928	0.490
TRG_ENDOCYTIC_2	1267	1270	PF00928	0.512
TRG_ENDOCYTIC_2	1715	1718	PF00928	0.421
TRG_ENDOCYTIC_2	1831	1834	PF00928	0.435
TRG_ENDOCYTIC_2	1920	1923	PF00928	0.388
TRG_ENDOCYTIC_2	404	407	PF00928	0.460
TRG_ENDOCYTIC_2	408	411	PF00928	0.443
TRG_ENDOCYTIC_2	449	452	PF00928	0.467
TRG_ENDOCYTIC_2	62	65	PF00928	0.477
TRG_ENDOCYTIC_2	657	660	PF00928	0.444
TRG_ER_diArg_1	1111	1113	PF00400	0.360
TRG_ER_diArg_1	1397	1399	PF00400	0.547
TRG_ER_diArg_1	1505	1507	PF00400	0.466
TRG_ER_diArg_1	1545	1547	PF00400	0.503
TRG_ER_diArg_1	1621	1623	PF00400	0.585
TRG_ER_diArg_1	1805	1807	PF00400	0.369
TRG_ER_diArg_1	235	237	PF00400	0.520
TRG_ER_diArg_1	734	736	PF00400	0.410
TRG_ER_diArg_1	852	854	PF00400	0.421
TRG_NES_CRM1_1	227	243	PF08389	0.356
TRG_NES_CRM1_1	746	760	PF08389	0.444
TRG_Pf-PMV_PEXEL_1	1218	1222	PF00026	0.387
TRG_Pf-PMV_PEXEL_1	1448	1453	PF00026	0.475
TRG_Pf-PMV_PEXEL_1	1568	1572	PF00026	0.406
TRG_Pf-PMV_PEXEL_1	1622	1626	PF00026	0.358
TRG_Pf-PMV_PEXEL_1	377	381	PF00026	0.469
TRG_Pf-PMV_PEXEL_1	54	58	PF00026	0.391
TRG_Pf-PMV_PEXEL_1	64	68	PF00026	0.408

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I7J0	Leptomonas seymouri	58%	89%
A0A0S4IYJ4	Bodo saltans	27%	85%
A0A1X0NL18	Trypanosomatidae	34%	99%
A0A3S5H5W1	Leishmania donovani	79%	92%
A4HT57	Leishmania infantum	79%	92%
C9ZUV9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	100%
E9AL22	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	94%
Q4QIT2	Leishmania major	79%	100%