Methionine synthase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Methionine synthase

Gene product:

cobalamin-dependent methionine synthase, putative

Species:

Leishmania braziliensis

UniProt:

A4H4V2_LEIBR

TriTrypDb:

LbrM.07.0090 , LBRM2903_070006100

Length:

1249

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0005829	cytosol	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4H4V2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H4V2

Function

Biological processes
Term	Name	Level	Count
GO:0006725	cellular aromatic compound metabolic process	3	8
GO:0006807	nitrogen compound metabolic process	2	8
GO:0008152	metabolic process	1	8
GO:0009987	cellular process	1	8
GO:0032259	methylation	2	8
GO:0042558	pteridine-containing compound metabolic process	4	8
GO:0044237	cellular metabolic process	2	8
GO:0046483	heterocycle metabolic process	3	8
GO:0071704	organic substance metabolic process	2	8
GO:1901360	organic cyclic compound metabolic process	3	8
GO:1901564	organonitrogen compound metabolic process	3	8
GO:0000096	sulfur amino acid metabolic process	4	1
GO:0000097	sulfur amino acid biosynthetic process	5	1
GO:0006082	organic acid metabolic process	3	1
GO:0006520	amino acid metabolic process	3	1
GO:0006555	methionine metabolic process	5	1
GO:0006790	sulfur compound metabolic process	3	1
GO:0008652	amino acid biosynthetic process	4	1
GO:0009058	biosynthetic process	2	1
GO:0009066	aspartate family amino acid metabolic process	5	1
GO:0009067	aspartate family amino acid biosynthetic process	6	1
GO:0009086	methionine biosynthetic process	6	1
GO:0016053	organic acid biosynthetic process	4	1
GO:0019752	carboxylic acid metabolic process	5	1
GO:0043436	oxoacid metabolic process	4	1
GO:0044238	primary metabolic process	2	1
GO:0044249	cellular biosynthetic process	3	1
GO:0044272	sulfur compound biosynthetic process	4	1
GO:0044281	small molecule metabolic process	2	1
GO:0044283	small molecule biosynthetic process	3	1
GO:0046394	carboxylic acid biosynthetic process	5	1
GO:1901566	organonitrogen compound biosynthetic process	4	1
GO:1901576	organic substance biosynthetic process	3	1
GO:1901605	alpha-amino acid metabolic process	4	1
GO:1901607	alpha-amino acid biosynthetic process	5	1

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	8
GO:0005488	binding	1	8
GO:0008168	methyltransferase activity	4	8
GO:0008172	S-methyltransferase activity	5	8
GO:0008270	zinc ion binding	6	8
GO:0008705	methionine synthase activity	6	8
GO:0016740	transferase activity	2	8
GO:0016741	transferase activity, transferring one-carbon groups	3	8
GO:0019842	vitamin binding	3	8
GO:0031419	cobalamin binding	4	8
GO:0036094	small molecule binding	2	8
GO:0042084	5-methyltetrahydrofolate-dependent methyltransferase activity	5	8
GO:0043167	ion binding	2	8
GO:0043169	cation binding	3	8
GO:0046872	metal ion binding	4	8
GO:0046906	tetrapyrrole binding	3	8
GO:0046914	transition metal ion binding	5	8
GO:0097159	organic cyclic compound binding	2	8
GO:1901363	heterocyclic compound binding	2	8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	105	107	PF00675	0.287
CLV_NRD_NRD_1	1229	1231	PF00675	0.287
CLV_NRD_NRD_1	128	130	PF00675	0.325
CLV_NRD_NRD_1	391	393	PF00675	0.228
CLV_NRD_NRD_1	478	480	PF00675	0.321
CLV_NRD_NRD_1	945	947	PF00675	0.546
CLV_PCSK_FUR_1	765	769	PF00082	0.597
CLV_PCSK_KEX2_1	105	107	PF00082	0.287
CLV_PCSK_KEX2_1	128	130	PF00082	0.287
CLV_PCSK_KEX2_1	18	20	PF00082	0.540
CLV_PCSK_KEX2_1	376	378	PF00082	0.399
CLV_PCSK_KEX2_1	478	480	PF00082	0.346
CLV_PCSK_KEX2_1	506	508	PF00082	0.346
CLV_PCSK_KEX2_1	767	769	PF00082	0.399
CLV_PCSK_KEX2_1	999	1001	PF00082	0.287
CLV_PCSK_PC1ET2_1	18	20	PF00082	0.540
CLV_PCSK_PC1ET2_1	376	378	PF00082	0.399
CLV_PCSK_PC1ET2_1	506	508	PF00082	0.346
CLV_PCSK_PC1ET2_1	767	769	PF00082	0.399
CLV_PCSK_PC1ET2_1	999	1001	PF00082	0.287
CLV_PCSK_SKI1_1	1047	1051	PF00082	0.377
CLV_PCSK_SKI1_1	128	132	PF00082	0.325
CLV_PCSK_SKI1_1	155	159	PF00082	0.287
CLV_PCSK_SKI1_1	18	22	PF00082	0.463
CLV_PCSK_SKI1_1	193	197	PF00082	0.287
CLV_PCSK_SKI1_1	377	381	PF00082	0.346
CLV_PCSK_SKI1_1	47	51	PF00082	0.293
CLV_PCSK_SKI1_1	723	727	PF00082	0.287
CLV_PCSK_SKI1_1	734	738	PF00082	0.287
CLV_PCSK_SKI1_1	751	755	PF00082	0.537
CLV_PCSK_SKI1_1	767	771	PF00082	0.417
CLV_PCSK_SKI1_1	839	843	PF00082	0.295
CLV_PCSK_SKI1_1	999	1003	PF00082	0.287
DEG_Nend_UBRbox_1	1	4	PF02207	0.428
DOC_CKS1_1	453	458	PF01111	0.399
DOC_CKS1_1	826	831	PF01111	0.487
DOC_CYCLIN_RxL_1	16	24	PF00134	0.446
DOC_CYCLIN_RxL_1	416	427	PF00134	0.218
DOC_CYCLIN_RxL_1	917	929	PF00134	0.504
DOC_CYCLIN_yClb5_NLxxxL_5	366	373	PF00134	0.218
DOC_CYCLIN_yCln2_LP_2	62	68	PF00134	0.577
DOC_MAPK_gen_1	1016	1026	PF00069	0.525
DOC_MAPK_gen_1	1060	1069	PF00069	0.525
DOC_MAPK_gen_1	337	346	PF00069	0.436
DOC_MAPK_gen_1	380	390	PF00069	0.399
DOC_MAPK_gen_1	478	486	PF00069	0.320
DOC_MAPK_gen_1	503	513	PF00069	0.346
DOC_MAPK_gen_1	734	744	PF00069	0.487
DOC_MAPK_gen_1	842	850	PF00069	0.487
DOC_MAPK_gen_1	917	926	PF00069	0.488
DOC_MAPK_gen_1	944	953	PF00069	0.549
DOC_MAPK_HePTP_8	237	249	PF00069	0.396
DOC_MAPK_MEF2A_6	1060	1069	PF00069	0.487
DOC_MAPK_MEF2A_6	240	249	PF00069	0.525
DOC_MAPK_MEF2A_6	737	744	PF00069	0.487
DOC_MAPK_MEF2A_6	783	790	PF00069	0.487
DOC_MAPK_MEF2A_6	843	852	PF00069	0.487
DOC_MAPK_MEF2A_6	928	936	PF00069	0.397
DOC_MAPK_MEF2A_6	987	996	PF00069	0.396
DOC_PP1_RVXF_1	920	927	PF00149	0.483
DOC_PP1_RVXF_1	931	937	PF00149	0.374
DOC_PP1_RVXF_1	962	968	PF00149	0.487
DOC_PP4_FxxP_1	1072	1075	PF00568	0.479
DOC_PP4_FxxP_1	846	849	PF00568	0.487
DOC_PP4_FxxP_1	989	992	PF00568	0.487
DOC_USP7_MATH_1	1014	1018	PF00917	0.547
DOC_USP7_MATH_1	1028	1032	PF00917	0.415
DOC_USP7_MATH_1	1197	1201	PF00917	0.490
DOC_USP7_MATH_1	328	332	PF00917	0.476
DOC_USP7_MATH_1	559	563	PF00917	0.348
DOC_USP7_MATH_1	581	585	PF00917	0.346
DOC_USP7_MATH_1	592	596	PF00917	0.346
DOC_USP7_MATH_1	629	633	PF00917	0.457
DOC_USP7_MATH_1	855	859	PF00917	0.487
DOC_USP7_MATH_1	879	883	PF00917	0.323
DOC_USP7_UBL2_3	1021	1025	PF12436	0.396
DOC_USP7_UBL2_3	1221	1225	PF12436	0.549
DOC_USP7_UBL2_3	376	380	PF12436	0.346
DOC_USP7_UBL2_3	47	51	PF12436	0.508
DOC_USP7_UBL2_3	839	843	PF12436	0.408
DOC_WW_Pin1_4	143	148	PF00397	0.487
DOC_WW_Pin1_4	3	8	PF00397	0.476
DOC_WW_Pin1_4	315	320	PF00397	0.577
DOC_WW_Pin1_4	452	457	PF00397	0.399
DOC_WW_Pin1_4	625	630	PF00397	0.457
DOC_WW_Pin1_4	754	759	PF00397	0.620
DOC_WW_Pin1_4	825	830	PF00397	0.463
DOC_WW_Pin1_4	965	970	PF00397	0.477
LIG_14-3-3_CanoR_1	1129	1139	PF00244	0.577
LIG_14-3-3_CanoR_1	155	160	PF00244	0.487
LIG_14-3-3_CanoR_1	340	345	PF00244	0.369
LIG_Actin_WH2_2	458	474	PF00022	0.399
LIG_APCC_ABBA_1	1036	1041	PF00400	0.487
LIG_APCC_ABBA_1	606	611	PF00400	0.461
LIG_APCC_ABBA_1	743	748	PF00400	0.457
LIG_BRCT_BRCA1_1	1210	1214	PF00533	0.487
LIG_BRCT_BRCA1_1	371	375	PF00533	0.346
LIG_BRCT_BRCA1_1	438	442	PF00533	0.346
LIG_BRCT_BRCA1_1	5	9	PF00533	0.443
LIG_BRCT_BRCA1_1	568	572	PF00533	0.346
LIG_BRCT_BRCA1_1	967	971	PF00533	0.504
LIG_CtBP_PxDLS_1	292	296	PF00389	0.525
LIG_deltaCOP1_diTrp_1	1134	1138	PF00928	0.396
LIG_deltaCOP1_diTrp_1	966	974	PF00928	0.487
LIG_eIF4E_1	98	104	PF01652	0.525
LIG_FHA_1	1122	1128	PF00498	0.453
LIG_FHA_1	1144	1150	PF00498	0.486
LIG_FHA_1	140	146	PF00498	0.487
LIG_FHA_1	169	175	PF00498	0.519
LIG_FHA_1	341	347	PF00498	0.450
LIG_FHA_1	353	359	PF00498	0.360
LIG_FHA_1	416	422	PF00498	0.326
LIG_FHA_1	453	459	PF00498	0.399
LIG_FHA_1	48	54	PF00498	0.525
LIG_FHA_1	61	67	PF00498	0.525
LIG_FHA_1	826	832	PF00498	0.487
LIG_FHA_1	871	877	PF00498	0.470
LIG_FHA_1	948	954	PF00498	0.442
LIG_FHA_1	98	104	PF00498	0.525
LIG_FHA_1	991	997	PF00498	0.396
LIG_FHA_2	1041	1047	PF00498	0.525
LIG_FHA_2	156	162	PF00498	0.487
LIG_FHA_2	183	189	PF00498	0.487
LIG_FHA_2	199	205	PF00498	0.487
LIG_FHA_2	216	222	PF00498	0.487
LIG_FHA_2	315	321	PF00498	0.525
LIG_FHA_2	531	537	PF00498	0.346
LIG_FHA_2	608	614	PF00498	0.455
LIG_FHA_2	656	662	PF00498	0.518
LIG_FHA_2	902	908	PF00498	0.451
LIG_FHA_2	950	956	PF00498	0.492
LIG_IRF3_LxIS_1	1065	1070	PF10401	0.577
LIG_LIR_Apic_2	1070	1075	PF02991	0.479
LIG_LIR_Gen_1	1064	1074	PF02991	0.495
LIG_LIR_Gen_1	1190	1201	PF02991	0.525
LIG_LIR_Gen_1	158	166	PF02991	0.487
LIG_LIR_Gen_1	184	195	PF02991	0.495
LIG_LIR_Gen_1	205	215	PF02991	0.487
LIG_LIR_Gen_1	233	244	PF02991	0.487
LIG_LIR_Gen_1	304	311	PF02991	0.416
LIG_LIR_Gen_1	418	428	PF02991	0.346
LIG_LIR_Gen_1	439	449	PF02991	0.316
LIG_LIR_Gen_1	6	16	PF02991	0.476
LIG_LIR_Gen_1	794	803	PF02991	0.577
LIG_LIR_Gen_1	895	905	PF02991	0.474
LIG_LIR_LC3C_4	1085	1088	PF02991	0.493
LIG_LIR_Nem_3	1050	1054	PF02991	0.477
LIG_LIR_Nem_3	1064	1069	PF02991	0.398
LIG_LIR_Nem_3	1105	1110	PF02991	0.487
LIG_LIR_Nem_3	1133	1139	PF02991	0.404
LIG_LIR_Nem_3	1211	1216	PF02991	0.487
LIG_LIR_Nem_3	153	157	PF02991	0.487
LIG_LIR_Nem_3	158	162	PF02991	0.487
LIG_LIR_Nem_3	184	190	PF02991	0.495
LIG_LIR_Nem_3	205	211	PF02991	0.487
LIG_LIR_Nem_3	304	310	PF02991	0.416
LIG_LIR_Nem_3	372	378	PF02991	0.383
LIG_LIR_Nem_3	418	423	PF02991	0.228
LIG_LIR_Nem_3	439	445	PF02991	0.316
LIG_LIR_Nem_3	569	575	PF02991	0.346
LIG_LIR_Nem_3	6	12	PF02991	0.432
LIG_LIR_Nem_3	794	798	PF02991	0.577
LIG_LIR_Nem_3	895	901	PF02991	0.483
LIG_LIR_Nem_3	903	908	PF02991	0.428
LIG_LIR_Nem_3	918	924	PF02991	0.457
LIG_LIR_Nem_3	966	970	PF02991	0.487
LIG_MLH1_MIPbox_1	1210	1214	PF16413	0.487
LIG_MLH1_MIPbox_1	967	971	PF16413	0.396
LIG_PAM2_1	188	200	PF00658	0.440
LIG_PCNA_PIPBox_1	712	721	PF02747	0.487
LIG_Pex14_1	69	73	PF04695	0.396
LIG_Pex14_1	967	971	PF04695	0.487
LIG_Pex14_2	1119	1123	PF04695	0.525
LIG_Pex14_2	970	974	PF04695	0.487
LIG_Pex14_2	985	989	PF04695	0.487
LIG_PTB_Apo_2	153	160	PF02174	0.487
LIG_PTB_Apo_2	564	571	PF02174	0.346
LIG_PTB_Apo_2	979	986	PF02174	0.517
LIG_PTB_Phospho_1	153	159	PF10480	0.487
LIG_Rb_pABgroove_1	197	205	PF01858	0.440
LIG_REV1ctd_RIR_1	1049	1059	PF16727	0.525
LIG_SH2_CRK	1107	1111	PF00017	0.487
LIG_SH2_CRK	1154	1158	PF00017	0.487
LIG_SH2_CRK	154	158	PF00017	0.487
LIG_SH2_CRK	208	212	PF00017	0.487
LIG_SH2_CRK	509	513	PF00017	0.346
LIG_SH2_CRK	921	925	PF00017	0.423
LIG_SH2_NCK_1	208	212	PF00017	0.466
LIG_SH2_NCK_1	288	292	PF00017	0.440
LIG_SH2_NCK_1	609	613	PF00017	0.449
LIG_SH2_NCK_1	75	79	PF00017	0.525
LIG_SH2_NCK_1	795	799	PF00017	0.466
LIG_SH2_SRC	159	162	PF00017	0.487
LIG_SH2_SRC	288	291	PF00017	0.396
LIG_SH2_SRC	905	908	PF00017	0.503
LIG_SH2_STAP1	159	163	PF00017	0.487
LIG_SH2_STAP1	166	170	PF00017	0.487
LIG_SH2_STAP1	498	502	PF00017	0.371
LIG_SH2_STAP1	509	513	PF00017	0.332
LIG_SH2_STAP1	541	545	PF00017	0.390
LIG_SH2_STAP1	638	642	PF00017	0.460
LIG_SH2_STAP1	816	820	PF00017	0.396
LIG_SH2_STAT3	1163	1166	PF00017	0.487
LIG_SH2_STAT3	166	169	PF00017	0.487
LIG_SH2_STAT3	98	101	PF00017	0.487
LIG_SH2_STAT5	1066	1069	PF00017	0.514
LIG_SH2_STAT5	1082	1085	PF00017	0.487
LIG_SH2_STAT5	1213	1216	PF00017	0.487
LIG_SH2_STAT5	1234	1237	PF00017	0.334
LIG_SH2_STAT5	166	169	PF00017	0.525
LIG_SH2_STAT5	208	211	PF00017	0.487
LIG_SH2_STAT5	236	239	PF00017	0.396
LIG_SH2_STAT5	261	264	PF00017	0.487
LIG_SH2_STAT5	272	275	PF00017	0.487
LIG_SH2_STAT5	353	356	PF00017	0.464
LIG_SH2_STAT5	609	612	PF00017	0.449
LIG_SH2_STAT5	912	915	PF00017	0.539
LIG_SH3_1	1158	1164	PF00018	0.487
LIG_SH3_1	330	336	PF00018	0.436
LIG_SH3_3	1158	1164	PF00018	0.487
LIG_SH3_3	132	138	PF00018	0.547
LIG_SH3_3	146	152	PF00018	0.415
LIG_SH3_3	330	336	PF00018	0.471
LIG_SH3_3	520	526	PF00018	0.429
LIG_SH3_3	739	745	PF00018	0.464
LIG_SH3_3	917	923	PF00018	0.527
LIG_SH3_3	934	940	PF00018	0.417
LIG_SH3_CIN85_PxpxPR_1	941	946	PF14604	0.533
LIG_Sin3_3	1020	1027	PF02671	0.525
LIG_SUMO_SIM_anti_2	750	757	PF11976	0.408
LIG_SUMO_SIM_anti_2	817	822	PF11976	0.448
LIG_SUMO_SIM_par_1	179	185	PF11976	0.525
LIG_SUMO_SIM_par_1	19	24	PF11976	0.402
LIG_SUMO_SIM_par_1	211	216	PF11976	0.525
LIG_SUMO_SIM_par_1	341	347	PF11976	0.380
LIG_SUMO_SIM_par_1	433	440	PF11976	0.321
LIG_SUMO_SIM_par_1	527	533	PF11976	0.310
LIG_SUMO_SIM_par_1	949	955	PF11976	0.445
LIG_TRAF2_1	667	670	PF00917	0.369
LIG_TRAF2_1	8	11	PF00917	0.305
LIG_TRAF2_1	904	907	PF00917	0.443
LIG_TYR_ITIM	157	162	PF00017	0.346
LIG_UBA3_1	186	193	PF00899	0.346
LIG_UBA3_1	59	67	PF00899	0.399
LIG_UBA3_1	672	678	PF00899	0.218
LIG_UBA3_1	708	714	PF00899	0.399
LIG_WRC_WIRS_1	1048	1053	PF05994	0.399
LIG_WW_3	332	336	PF00397	0.505
MOD_CDK_SPK_2	754	759	PF00069	0.443
MOD_CDK_SPxxK_3	754	761	PF00069	0.449
MOD_CK1_1	123	129	PF00069	0.471
MOD_CK1_1	1240	1246	PF00069	0.563
MOD_CK1_1	223	229	PF00069	0.346
MOD_CK1_1	566	572	PF00069	0.316
MOD_CK1_1	882	888	PF00069	0.325
MOD_CK2_1	1040	1046	PF00069	0.399
MOD_CK2_1	155	161	PF00069	0.346
MOD_CK2_1	344	350	PF00069	0.452
MOD_CK2_1	530	536	PF00069	0.346
MOD_CK2_1	607	613	PF00069	0.452
MOD_CK2_1	827	833	PF00069	0.346
MOD_CK2_1	889	895	PF00069	0.537
MOD_CK2_1	901	907	PF00069	0.382
MOD_CK2_1	93	99	PF00069	0.432
MOD_Cter_Amidation	126	129	PF01082	0.335
MOD_GlcNHglycan	1201	1204	PF01048	0.354
MOD_GlcNHglycan	215	218	PF01048	0.346
MOD_GlcNHglycan	221	225	PF01048	0.346
MOD_GlcNHglycan	227	230	PF01048	0.346
MOD_GlcNHglycan	346	349	PF01048	0.440
MOD_GlcNHglycan	369	372	PF01048	0.346
MOD_GlcNHglycan	561	564	PF01048	0.316
MOD_GlcNHglycan	583	586	PF01048	0.341
MOD_GlcNHglycan	720	723	PF01048	0.375
MOD_GlcNHglycan	731	734	PF01048	0.297
MOD_GlcNHglycan	823	826	PF01048	0.312
MOD_GSK3_1	1167	1174	PF00069	0.346
MOD_GSK3_1	1237	1244	PF00069	0.563
MOD_GSK3_1	139	146	PF00069	0.346
MOD_GSK3_1	164	171	PF00069	0.391
MOD_GSK3_1	182	189	PF00069	0.439
MOD_GSK3_1	213	220	PF00069	0.346
MOD_GSK3_1	340	347	PF00069	0.450
MOD_GSK3_1	493	500	PF00069	0.218
MOD_GSK3_1	559	566	PF00069	0.313
MOD_GSK3_1	625	632	PF00069	0.446
MOD_GSK3_1	759	766	PF00069	0.631
MOD_GSK3_1	821	828	PF00069	0.346
MOD_GSK3_1	855	862	PF00069	0.346
MOD_GSK3_1	93	100	PF00069	0.395
MOD_GSK3_1	947	954	PF00069	0.429
MOD_GSK3_1	965	972	PF00069	0.218
MOD_N-GLC_1	139	144	PF02516	0.346
MOD_N-GLC_1	155	160	PF02516	0.346
MOD_N-GLC_1	367	372	PF02516	0.346
MOD_N-GLC_1	47	52	PF02516	0.399
MOD_N-GLC_1	566	571	PF02516	0.346
MOD_N-GLC_1	625	630	PF02516	0.452
MOD_NEK2_1	1189	1194	PF00069	0.383
MOD_NEK2_1	1242	1247	PF00069	0.484
MOD_NEK2_1	139	144	PF00069	0.386
MOD_NEK2_1	182	187	PF00069	0.346
MOD_NEK2_1	235	240	PF00069	0.399
MOD_NEK2_1	344	349	PF00069	0.394
MOD_NEK2_1	352	357	PF00069	0.441
MOD_NEK2_1	369	374	PF00069	0.190
MOD_NEK2_1	436	441	PF00069	0.323
MOD_NEK2_1	449	454	PF00069	0.346
MOD_NEK2_1	568	573	PF00069	0.346
MOD_NEK2_1	60	65	PF00069	0.346
MOD_NEK2_1	718	723	PF00069	0.399
MOD_NEK2_1	770	775	PF00069	0.264
MOD_NEK2_1	877	882	PF00069	0.431
MOD_NEK2_1	889	894	PF00069	0.455
MOD_NEK2_2	1014	1019	PF00069	0.471
MOD_NEK2_2	198	203	PF00069	0.346
MOD_NEK2_2	271	276	PF00069	0.399
MOD_NEK2_2	870	875	PF00069	0.543
MOD_PIKK_1	1162	1168	PF00454	0.346
MOD_PIKK_1	1237	1243	PF00454	0.557
MOD_PIKK_1	449	455	PF00454	0.316
MOD_PIKK_1	60	66	PF00454	0.346
MOD_PIKK_1	91	97	PF00454	0.331
MOD_PK_1	141	147	PF00069	0.346
MOD_PK_1	759	765	PF00069	0.446
MOD_PKA_2	1140	1146	PF00069	0.218
MOD_PKA_2	339	345	PF00069	0.347
MOD_PKA_2	976	982	PF00069	0.399
MOD_Plk_1	1040	1046	PF00069	0.218
MOD_Plk_1	155	161	PF00069	0.346
MOD_Plk_1	566	572	PF00069	0.346
MOD_Plk_2-3	1121	1127	PF00069	0.399
MOD_Plk_4	1047	1053	PF00069	0.346
MOD_Plk_4	1082	1088	PF00069	0.367
MOD_Plk_4	1171	1177	PF00069	0.399
MOD_Plk_4	182	188	PF00069	0.346
MOD_Plk_4	198	204	PF00069	0.346
MOD_Plk_4	26	32	PF00069	0.346
MOD_Plk_4	879	885	PF00069	0.335
MOD_ProDKin_1	143	149	PF00069	0.346
MOD_ProDKin_1	3	9	PF00069	0.465
MOD_ProDKin_1	315	321	PF00069	0.471
MOD_ProDKin_1	452	458	PF00069	0.399
MOD_ProDKin_1	625	631	PF00069	0.450
MOD_ProDKin_1	754	760	PF00069	0.622
MOD_ProDKin_1	825	831	PF00069	0.312
MOD_ProDKin_1	965	971	PF00069	0.332
MOD_SUMO_for_1	642	645	PF00179	0.548
MOD_SUMO_rev_2	40	49	PF00179	0.471
MOD_SUMO_rev_2	496	502	PF00179	0.218
MOD_SUMO_rev_2	653	658	PF00179	0.684
TRG_DiLeu_BaEn_1	1145	1150	PF01217	0.374
TRG_DiLeu_BaEn_1	750	755	PF01217	0.648
TRG_DiLeu_BaEn_1	99	104	PF01217	0.390
TRG_DiLeu_BaEn_3	1125	1131	PF01217	0.346
TRG_DiLeu_BaLyEn_6	472	477	PF01217	0.399
TRG_DiLeu_BaLyEn_6	668	673	PF01217	0.218
TRG_ENDOCYTIC_2	1066	1069	PF00928	0.399
TRG_ENDOCYTIC_2	1107	1110	PF00928	0.346
TRG_ENDOCYTIC_2	1154	1157	PF00928	0.346
TRG_ENDOCYTIC_2	1193	1196	PF00928	0.399
TRG_ENDOCYTIC_2	1213	1216	PF00928	0.141
TRG_ENDOCYTIC_2	154	157	PF00928	0.346
TRG_ENDOCYTIC_2	159	162	PF00928	0.346
TRG_ENDOCYTIC_2	208	211	PF00928	0.346
TRG_ENDOCYTIC_2	236	239	PF00928	0.346
TRG_ENDOCYTIC_2	509	512	PF00928	0.346
TRG_ENDOCYTIC_2	609	612	PF00928	0.449
TRG_ENDOCYTIC_2	795	798	PF00928	0.346
TRG_ENDOCYTIC_2	905	908	PF00928	0.449
TRG_ENDOCYTIC_2	921	924	PF00928	0.417
TRG_ER_diArg_1	104	106	PF00400	0.348
TRG_ER_diArg_1	128	130	PF00400	0.399
TRG_ER_diArg_1	477	479	PF00400	0.346
TRG_ER_diArg_1	943	946	PF00400	0.543
TRG_Pf-PMV_PEXEL_1	19	24	PF00026	0.399
TRG_Pf-PMV_PEXEL_1	225	230	PF00026	0.346

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7K4	Leptomonas seymouri	86%	100%
A0A0S4ISL0	Bodo saltans	65%	96%
A0A3S5H5V8	Leishmania donovani	90%	100%
A4HT60	Leishmania infantum	90%	100%
A6H5Y3	Mus musculus	55%	100%
A8XY95	Caenorhabditis briggsae	53%	98%
E9AL19	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
O33259	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	30%	100%
P13009	Escherichia coli (strain K12)	52%	100%
P37586	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	52%	100%
Q09582	Caenorhabditis elegans	54%	100%
Q49775	Mycobacterium leprae (strain TN)	31%	100%
Q4JIJ3	Bos taurus	57%	99%
Q4QIT5	Leishmania major	90%	100%
Q54P92	Dictyostelium discoideum	55%	99%
Q55786	Synechocystis sp. (strain PCC 6803 / Kazusa)	32%	100%
Q5E814	Aliivibrio fischeri (strain ATCC 700601 / ES114)	51%	100%
Q7MHB1	Vibrio vulnificus (strain YJ016)	52%	100%
Q87L95	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	52%	100%
Q8DCJ7	Vibrio vulnificus (strain CMCP6)	51%	100%
Q99707	Homo sapiens	56%	99%
Q9AJQ8	Aliivibrio fischeri	52%	100%
Q9I2Q2	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	52%	100%
Q9KUW9	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	51%	100%
Q9Z2Q4	Rattus norvegicus	55%	100%