CLASP_N domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H4U7_LEIBR

TriTrypDb:

LbrM.07.0040 , LBRM2903_070005500

Length:

314

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H4U7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H4U7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	224	226	PF00675	0.758
CLV_NRD_NRD_1	241	243	PF00675	0.509
CLV_NRD_NRD_1	299	301	PF00675	0.702
CLV_PCSK_FUR_1	297	301	PF00082	0.795
CLV_PCSK_KEX2_1	105	107	PF00082	0.417
CLV_PCSK_KEX2_1	239	241	PF00082	0.728
CLV_PCSK_KEX2_1	296	298	PF00082	0.671
CLV_PCSK_KEX2_1	299	301	PF00082	0.693
CLV_PCSK_PC1ET2_1	105	107	PF00082	0.346
CLV_PCSK_PC1ET2_1	239	241	PF00082	0.728
CLV_PCSK_PC1ET2_1	296	298	PF00082	0.671
CLV_PCSK_SKI1_1	102	106	PF00082	0.603
CLV_PCSK_SKI1_1	212	216	PF00082	0.690
CLV_PCSK_SKI1_1	226	230	PF00082	0.662
CLV_PCSK_SKI1_1	300	304	PF00082	0.813
CLV_PCSK_SKI1_1	59	63	PF00082	0.422
DEG_APCC_DBOX_1	211	219	PF00400	0.688
DOC_CKS1_1	266	271	PF01111	0.571
DOC_MAPK_DCC_7	106	116	PF00069	0.353
DOC_MAPK_gen_1	102	112	PF00069	0.503
DOC_MAPK_gen_1	296	306	PF00069	0.697
DOC_MAPK_gen_1	54	62	PF00069	0.560
DOC_MAPK_MEF2A_6	105	114	PF00069	0.487
DOC_USP7_MATH_1	168	172	PF00917	0.700
DOC_USP7_MATH_1	200	204	PF00917	0.636
DOC_USP7_MATH_1	63	67	PF00917	0.503
DOC_USP7_UBL2_3	139	143	PF12436	0.513
DOC_WW_Pin1_4	119	124	PF00397	0.471
DOC_WW_Pin1_4	178	183	PF00397	0.698
DOC_WW_Pin1_4	205	210	PF00397	0.646
DOC_WW_Pin1_4	265	270	PF00397	0.763
DOC_WW_Pin1_4	290	295	PF00397	0.669
DOC_WW_Pin1_4	306	311	PF00397	0.697
DOC_WW_Pin1_4	4	9	PF00397	0.619
LIG_14-3-3_CanoR_1	100	107	PF00244	0.598
LIG_14-3-3_CanoR_1	118	122	PF00244	0.294
LIG_14-3-3_CanoR_1	169	177	PF00244	0.636
LIG_14-3-3_CanoR_1	225	235	PF00244	0.672
LIG_Actin_WH2_2	103	120	PF00022	0.584
LIG_BIR_II_1	1	5	PF00653	0.588
LIG_FHA_1	12	18	PF00498	0.476
LIG_FHA_1	120	126	PF00498	0.467
LIG_FHA_1	21	27	PF00498	0.586
LIG_FHA_1	227	233	PF00498	0.671
LIG_FHA_1	301	307	PF00498	0.802
LIG_FHA_1	41	47	PF00498	0.357
LIG_FHA_1	56	62	PF00498	0.603
LIG_FHA_1	73	79	PF00498	0.332
LIG_FHA_2	181	187	PF00498	0.734
LIG_FHA_2	253	259	PF00498	0.723
LIG_FHA_2	273	279	PF00498	0.605
LIG_FHA_2	83	89	PF00498	0.429
LIG_LIR_Gen_1	74	84	PF02991	0.432
LIG_LIR_Nem_3	74	80	PF02991	0.443
LIG_NRBOX	85	91	PF00104	0.535
LIG_SH2_NCK_1	185	189	PF00017	0.542
LIG_SH2_STAT5	235	238	PF00017	0.597
LIG_SH3_1	263	269	PF00018	0.573
LIG_SH3_2	307	312	PF14604	0.702
LIG_SH3_3	107	113	PF00018	0.436
LIG_SH3_3	174	180	PF00018	0.802
LIG_SH3_3	203	209	PF00018	0.707
LIG_SH3_3	263	269	PF00018	0.684
LIG_SH3_3	301	307	PF00018	0.713
LIG_SUMO_SIM_par_1	287	293	PF11976	0.677
LIG_SUMO_SIM_par_1	81	88	PF11976	0.319
LIG_SxIP_EBH_1	225	238	PF03271	0.744
LIG_TRAF2_1	208	211	PF00917	0.663
LIG_UBA3_1	288	296	PF00899	0.670
MOD_CDC14_SPxK_1	293	296	PF00782	0.670
MOD_CDC14_SPxK_1	309	312	PF00782	0.707
MOD_CDK_SPxK_1	290	296	PF00069	0.671
MOD_CDK_SPxK_1	306	312	PF00069	0.702
MOD_CDK_SPxxK_3	205	212	PF00069	0.534
MOD_CDK_SPxxK_3	290	297	PF00069	0.672
MOD_CK1_1	178	184	PF00069	0.604
MOD_CK1_1	251	257	PF00069	0.810
MOD_CK1_1	68	74	PF00069	0.600
MOD_CK2_1	180	186	PF00069	0.713
MOD_CK2_1	190	196	PF00069	0.594
MOD_CK2_1	205	211	PF00069	0.608
MOD_CK2_1	82	88	PF00069	0.427
MOD_GlcNHglycan	140	143	PF01048	0.665
MOD_GlcNHglycan	192	195	PF01048	0.622
MOD_GlcNHglycan	202	205	PF01048	0.532
MOD_GlcNHglycan	229	232	PF01048	0.658
MOD_GlcNHglycan	248	251	PF01048	0.624
MOD_GlcNHglycan	67	70	PF01048	0.678
MOD_GlcNHglycan	91	94	PF01048	0.456
MOD_GSK3_1	117	124	PF00069	0.584
MOD_GSK3_1	227	234	PF00069	0.654
MOD_GSK3_1	246	253	PF00069	0.684
MOD_GSK3_1	268	275	PF00069	0.662
MOD_GSK3_1	40	47	PF00069	0.439
MOD_GSK3_1	68	75	PF00069	0.600
MOD_N-GLC_1	175	180	PF02516	0.553
MOD_N-GLC_1	226	231	PF02516	0.509
MOD_N-GLC_1	71	76	PF02516	0.521
MOD_NEK2_1	116	121	PF00069	0.479
MOD_NEK2_1	138	143	PF00069	0.605
MOD_NEK2_1	252	257	PF00069	0.597
MOD_NEK2_1	89	94	PF00069	0.449
MOD_PKA_2	117	123	PF00069	0.580
MOD_PKA_2	168	174	PF00069	0.748
MOD_PKA_2	55	61	PF00069	0.497
MOD_PKB_1	298	306	PF00069	0.763
MOD_PKB_1	98	106	PF00069	0.606
MOD_Plk_1	188	194	PF00069	0.526
MOD_Plk_1	300	306	PF00069	0.803
MOD_Plk_4	121	127	PF00069	0.565
MOD_Plk_4	231	237	PF00069	0.627
MOD_Plk_4	272	278	PF00069	0.676
MOD_Plk_4	284	290	PF00069	0.453
MOD_ProDKin_1	119	125	PF00069	0.468
MOD_ProDKin_1	178	184	PF00069	0.695
MOD_ProDKin_1	205	211	PF00069	0.649
MOD_ProDKin_1	265	271	PF00069	0.761
MOD_ProDKin_1	290	296	PF00069	0.671
MOD_ProDKin_1	306	312	PF00069	0.702
MOD_ProDKin_1	4	10	PF00069	0.615
MOD_SUMO_rev_2	193	200	PF00179	0.769
TRG_DiLeu_BaEn_1	57	62	PF01217	0.606
TRG_ER_diArg_1	240	242	PF00400	0.611
TRG_ER_diArg_1	297	300	PF00400	0.692
TRG_NLS_Bipartite_1	225	243	PF00514	0.748
TRG_NLS_MonoCore_2	238	243	PF00514	0.754
TRG_NLS_MonoCore_2	295	300	PF00514	0.676
TRG_NLS_MonoExtC_3	238	244	PF00514	0.755
TRG_NLS_MonoExtC_3	295	300	PF00514	0.686
TRG_NLS_MonoExtN_4	294	300	PF00514	0.684
TRG_Pf-PMV_PEXEL_1	59	64	PF00026	0.459

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZD5	Leptomonas seymouri	41%	100%
A0A3S7WPQ1	Leishmania donovani	73%	100%
A4HT26	Leishmania infantum	73%	100%
E9AL14	Leishmania mexicana (strain MHOM/GT/2001/U1103)	74%	99%
Q4QIU0	Leishmania major	74%	100%