LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania braziliensis
UniProt:
A4H4T2_LEIBR
TriTrypDb:
LbrM.06.1190 , LBRM2903_060019300 *
Length:
394

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H4T2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H4T2

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 190 194 PF00656 0.565
CLV_C14_Caspase3-7 224 228 PF00656 0.571
CLV_C14_Caspase3-7 281 285 PF00656 0.796
CLV_NRD_NRD_1 143 145 PF00675 0.683
CLV_NRD_NRD_1 152 154 PF00675 0.625
CLV_NRD_NRD_1 306 308 PF00675 0.684
CLV_NRD_NRD_1 325 327 PF00675 0.723
CLV_NRD_NRD_1 359 361 PF00675 0.698
CLV_NRD_NRD_1 86 88 PF00675 0.489
CLV_PCSK_KEX2_1 308 310 PF00082 0.712
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P4J6 Leptomonas seymouri 41% 100%
A0A3S5H5U8 Leishmania donovani 69% 100%
A4HT11 Leishmania infantum 70% 100%
E9AKZ9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 67% 100%
Q4QIV6 Leishmania major 68% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS