Putative acyl-coenzyme a dehydrogenase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

acyl-coenzyme a dehydrogenase, putative

Species:

Leishmania braziliensis

UniProt:

A4H4Q0_LEIBR

TriTrypDb:

LbrM.06.0850 , LBRM2903_060015500

Length:

511

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 8

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 1, no: 10
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005739	mitochondrion	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4H4Q0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H4Q0

Function

Biological processes
Term	Name	Level	Count
GO:0006082	organic acid metabolic process	3	1
GO:0006629	lipid metabolic process	3	1
GO:0006631	fatty acid metabolic process	4	1
GO:0006635	fatty acid beta-oxidation	6	1
GO:0008152	metabolic process	1	1
GO:0009056	catabolic process	2	1
GO:0009062	fatty acid catabolic process	5	1
GO:0009987	cellular process	1	1
GO:0016042	lipid catabolic process	4	1
GO:0016054	organic acid catabolic process	4	1
GO:0019395	fatty acid oxidation	5	1
GO:0019752	carboxylic acid metabolic process	5	1
GO:0030258	lipid modification	4	1
GO:0032787	monocarboxylic acid metabolic process	6	1
GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	7	1
GO:0034440	lipid oxidation	5	1
GO:0043436	oxoacid metabolic process	4	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044242	cellular lipid catabolic process	4	1
GO:0044248	cellular catabolic process	3	1
GO:0044255	cellular lipid metabolic process	3	1
GO:0044281	small molecule metabolic process	2	1
GO:0044282	small molecule catabolic process	3	1
GO:0046395	carboxylic acid catabolic process	5	1
GO:0051791	medium-chain fatty acid metabolic process	5	1
GO:0051793	medium-chain fatty acid catabolic process	6	1
GO:0071704	organic substance metabolic process	2	1
GO:0072329	monocarboxylic acid catabolic process	6	1
GO:1901575	organic substance catabolic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003824	catalytic activity	1	12
GO:0003995	acyl-CoA dehydrogenase activity	5	11
GO:0005488	binding	1	12
GO:0016491	oxidoreductase activity	2	12
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	3	12
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	4	6
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0043958	acryloyl-CoA reductase (NADH) activity	5	6
GO:0050660	flavin adenine dinucleotide binding	4	12
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	4	11
GO:0097159	organic cyclic compound binding	2	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12
GO:0070991	medium-chain-acyl-CoA dehydrogenase activity	6	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	200	204	PF00656	0.429
CLV_NRD_NRD_1	24	26	PF00675	0.448
CLV_NRD_NRD_1	275	277	PF00675	0.286
CLV_NRD_NRD_1	384	386	PF00675	0.328
CLV_NRD_NRD_1	439	441	PF00675	0.390
CLV_NRD_NRD_1	7	9	PF00675	0.505
CLV_NRD_NRD_1	70	72	PF00675	0.488
CLV_NRD_NRD_1	73	75	PF00675	0.473
CLV_PCSK_FUR_1	71	75	PF00082	0.482
CLV_PCSK_KEX2_1	384	386	PF00082	0.336
CLV_PCSK_KEX2_1	439	441	PF00082	0.390
CLV_PCSK_KEX2_1	7	9	PF00082	0.734
CLV_PCSK_KEX2_1	70	72	PF00082	0.488
CLV_PCSK_KEX2_1	73	75	PF00082	0.473
CLV_PCSK_SKI1_1	168	172	PF00082	0.443
CLV_PCSK_SKI1_1	339	343	PF00082	0.255
CLV_PCSK_SKI1_1	384	388	PF00082	0.390
CLV_PCSK_SKI1_1	425	429	PF00082	0.429
CLV_PCSK_SKI1_1	458	462	PF00082	0.215
CLV_PCSK_SKI1_1	504	508	PF00082	0.458
DEG_Nend_UBRbox_1	1	4	PF02207	0.499
DEG_SCF_FBW7_1	12	18	PF00400	0.483
DOC_CDC14_PxL_1	227	235	PF14671	0.463
DOC_CKS1_1	12	17	PF01111	0.482
DOC_MAPK_MEF2A_6	38	47	PF00069	0.427
DOC_PP1_RVXF_1	337	344	PF00149	0.317
DOC_PP2B_LxvP_1	43	46	PF13499	0.420
DOC_PP2B_LxvP_1	75	78	PF13499	0.456
DOC_PP4_FxxP_1	32	35	PF00568	0.453
DOC_USP7_MATH_1	129	133	PF00917	0.612
DOC_USP7_MATH_1	46	50	PF00917	0.413
DOC_USP7_MATH_1	88	92	PF00917	0.413
DOC_WW_Pin1_4	106	111	PF00397	0.602
DOC_WW_Pin1_4	11	16	PF00397	0.485
DOC_WW_Pin1_4	27	32	PF00397	0.432
DOC_WW_Pin1_4	62	67	PF00397	0.480
DOC_WW_Pin1_4	73	78	PF00397	0.444
LIG_14-3-3_CanoR_1	25	31	PF00244	0.465
LIG_14-3-3_CanoR_1	334	341	PF00244	0.336
LIG_14-3-3_CanoR_1	372	376	PF00244	0.442
LIG_14-3-3_CanoR_1	384	393	PF00244	0.388
LIG_14-3-3_CanoR_1	397	401	PF00244	0.292
LIG_14-3-3_CanoR_1	425	430	PF00244	0.393
LIG_14-3-3_CanoR_1	439	444	PF00244	0.250
LIG_14-3-3_CanoR_1	87	96	PF00244	0.602
LIG_14-3-3_CanoR_1	97	104	PF00244	0.578
LIG_Actin_WH2_2	99	114	PF00022	0.680
LIG_BRCT_BRCA1_1	297	301	PF00533	0.223
LIG_BRCT_BRCA1_1	75	79	PF00533	0.456
LIG_FHA_1	309	315	PF00498	0.365
LIG_FHA_1	336	342	PF00498	0.290
LIG_FHA_1	459	465	PF00498	0.351
LIG_FHA_1	492	498	PF00498	0.336
LIG_FHA_2	218	224	PF00498	0.303
LIG_FHA_2	321	327	PF00498	0.442
LIG_FHA_2	35	41	PF00498	0.441
LIG_LIR_Apic_2	29	35	PF02991	0.642
LIG_LIR_Gen_1	342	349	PF02991	0.357
LIG_LIR_Gen_1	48	55	PF02991	0.419
LIG_LIR_Nem_3	192	197	PF02991	0.395
LIG_LIR_Nem_3	298	303	PF02991	0.325
LIG_LIR_Nem_3	307	313	PF02991	0.316
LIG_LIR_Nem_3	342	346	PF02991	0.357
LIG_LIR_Nem_3	40	45	PF02991	0.429
LIG_LIR_Nem_3	48	53	PF02991	0.400
LIG_MLH1_MIPbox_1	297	301	PF16413	0.223
LIG_PCNA_yPIPBox_3	288	300	PF02747	0.317
LIG_SH2_CRK	194	198	PF00017	0.377
LIG_SH2_STAP1	166	170	PF00017	0.429
LIG_SH2_STAP1	444	448	PF00017	0.327
LIG_SH2_STAT5	244	247	PF00017	0.368
LIG_SH2_STAT5	257	260	PF00017	0.280
LIG_SH2_STAT5	300	303	PF00017	0.360
LIG_SH2_STAT5	310	313	PF00017	0.317
LIG_SH2_STAT5	505	508	PF00017	0.562
LIG_SH3_2	66	71	PF14604	0.484
LIG_SH3_3	246	252	PF00018	0.360
LIG_SH3_3	256	262	PF00018	0.267
LIG_SH3_3	343	349	PF00018	0.317
LIG_SH3_3	351	357	PF00018	0.405
LIG_SH3_3	63	69	PF00018	0.481
LIG_SH3_3	9	15	PF00018	0.601
LIG_SH3_4	402	409	PF00018	0.463
LIG_UBA3_1	21	26	PF00899	0.489
LIG_WRC_WIRS_1	47	52	PF05994	0.411
MOD_CDC14_SPxK_1	68	71	PF00782	0.484
MOD_CDK_SPK_2	65	70	PF00069	0.482
MOD_CDK_SPxK_1	106	112	PF00069	0.603
MOD_CDK_SPxK_1	65	71	PF00069	0.483
MOD_CK1_1	116	122	PF00069	0.556
MOD_CK1_1	65	71	PF00069	0.483
MOD_CK1_1	82	88	PF00069	0.384
MOD_CK2_1	320	326	PF00069	0.451
MOD_CK2_1	34	40	PF00069	0.446
MOD_CK2_1	486	492	PF00069	0.317
MOD_CK2_1	53	59	PF00069	0.401
MOD_Cter_Amidation	437	440	PF01082	0.390
MOD_DYRK1A_RPxSP_1	11	15	PF00069	0.486
MOD_GlcNHglycan	131	134	PF01048	0.521
MOD_GlcNHglycan	81	84	PF01048	0.423
MOD_GlcNHglycan	90	93	PF01048	0.390
MOD_GSK3_1	11	18	PF00069	0.485
MOD_GSK3_1	134	141	PF00069	0.470
MOD_GSK3_1	213	220	PF00069	0.325
MOD_GSK3_1	26	33	PF00069	0.433
MOD_GSK3_1	335	342	PF00069	0.344
MOD_GSK3_1	380	387	PF00069	0.467
MOD_GSK3_1	439	446	PF00069	0.336
MOD_GSK3_1	500	507	PF00069	0.380
MOD_N-GLC_1	284	289	PF02516	0.429
MOD_NEK2_1	1	6	PF00069	0.495
MOD_NEK2_1	113	118	PF00069	0.475
MOD_NEK2_1	123	128	PF00069	0.608
MOD_NEK2_1	183	188	PF00069	0.433
MOD_NEK2_1	197	202	PF00069	0.238
MOD_NEK2_1	271	276	PF00069	0.292
MOD_NEK2_1	289	294	PF00069	0.315
MOD_NEK2_1	368	373	PF00069	0.317
MOD_NEK2_1	53	58	PF00069	0.434
MOD_NEK2_1	79	84	PF00069	0.692
MOD_NEK2_1	96	101	PF00069	0.579
MOD_NEK2_2	166	171	PF00069	0.463
MOD_OFUCOSY	80	86	PF10250	0.423
MOD_PIKK_1	2	8	PF00454	0.496
MOD_PIKK_1	492	498	PF00454	0.336
MOD_PK_1	486	492	PF00069	0.317
MOD_PKA_1	384	390	PF00069	0.429
MOD_PKA_1	439	445	PF00069	0.390
MOD_PKA_2	1	7	PF00069	0.645
MOD_PKA_2	10	16	PF00069	0.467
MOD_PKA_2	333	339	PF00069	0.336
MOD_PKA_2	371	377	PF00069	0.445
MOD_PKA_2	384	390	PF00069	0.384
MOD_PKA_2	396	402	PF00069	0.301
MOD_PKA_2	439	445	PF00069	0.390
MOD_PKA_2	88	94	PF00069	0.597
MOD_PKA_2	96	102	PF00069	0.575
MOD_Plk_1	166	172	PF00069	0.336
MOD_Plk_1	388	394	PF00069	0.301
MOD_Plk_4	197	203	PF00069	0.395
MOD_Plk_4	295	301	PF00069	0.425
MOD_Plk_4	439	445	PF00069	0.307
MOD_Plk_4	497	503	PF00069	0.260
MOD_ProDKin_1	106	112	PF00069	0.603
MOD_ProDKin_1	11	17	PF00069	0.484
MOD_ProDKin_1	27	33	PF00069	0.429
MOD_ProDKin_1	62	68	PF00069	0.478
MOD_ProDKin_1	73	79	PF00069	0.443
MOD_SUMO_rev_2	479	488	PF00179	0.317
TRG_DiLeu_BaEn_1	229	234	PF01217	0.463
TRG_DiLeu_BaEn_1	422	427	PF01217	0.317
TRG_DiLeu_BaLyEn_6	17	22	PF01217	0.495
TRG_DiLeu_BaLyEn_6	228	233	PF01217	0.390
TRG_DiLeu_BaLyEn_6	249	254	PF01217	0.498
TRG_ENDOCYTIC_2	194	197	PF00928	0.329
TRG_ENDOCYTIC_2	300	303	PF00928	0.317
TRG_ENDOCYTIC_2	310	313	PF00928	0.317
TRG_ER_diArg_1	69	71	PF00400	0.488
TRG_ER_diArg_1	73	75	PF00400	0.471

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0C6DRW4	Rhodococcus erythropolis	23%	100%
A0A0N0P3D6	Leptomonas seymouri	27%	81%
A0A0N1HXP9	Leptomonas seymouri	82%	100%
A0A0N1I6H4	Leptomonas seymouri	32%	100%
A0A0N1IMF9	Leptomonas seymouri	34%	100%
A0A0S4IM43	Bodo saltans	34%	100%
A0A0S4IUT5	Bodo saltans	29%	70%
A0A0S4IY66	Bodo saltans	28%	100%
A0A0S4J7W1	Bodo saltans	33%	100%
A0A0S4JFP0	Bodo saltans	38%	100%
A0A0S4JQE6	Bodo saltans	24%	79%
A0A0S4KIH4	Bodo saltans	69%	100%
A0A1X0NL04	Trypanosomatidae	63%	100%
A0A1X0NQM6	Trypanosomatidae	28%	82%
A0A1X0P4C4	Trypanosomatidae	34%	100%
A0A1X0P5J1	Trypanosomatidae	35%	100%
A0A3Q8IIB9	Leishmania donovani	27%	81%
A0A3Q8IVB5	Leishmania donovani	35%	100%
A0A3R7LB59	Trypanosoma rangeli	61%	100%
A0A3R7LXK2	Trypanosoma rangeli	28%	100%
A0A3S5H5T1	Leishmania donovani	88%	100%
A0A3S7X0K3	Leishmania donovani	32%	100%
A0A422N1U9	Trypanosoma rangeli	33%	100%
A0A422NKY7	Trypanosoma rangeli	26%	82%
A0R4Z9	Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)	28%	100%
A1A789	Escherichia coli O1:K1 / APEC	29%	100%
A4H4Q2	Leishmania braziliensis	100%	100%
A4HFL6	Leishmania braziliensis	31%	100%
A4HGV3	Leishmania braziliensis	28%	81%
A4HMU0	Leishmania braziliensis	36%	100%
A4HSY0	Leishmania infantum	88%	100%
A4I353	Leishmania infantum	32%	100%
A4I3Y3	Leishmania infantum	28%	81%
A4IBE1	Leishmania infantum	35%	100%
A5A6I0	Pan troglodytes	61%	100%
A7ZHD0	Escherichia coli O139:H28 (strain E24377A / ETEC)	29%	100%
A7ZVY9	Escherichia coli O9:H4 (strain HS)	29%	100%
A8ALR4	Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)	28%	100%
A8WP91	Caenorhabditis briggsae	50%	100%
A8XNF0	Caenorhabditis briggsae	52%	100%
A9MQH5	Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)	30%	100%
A9MYJ9	Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)	28%	100%
B1IRD7	Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks)	29%	100%
B1LFX2	Escherichia coli (strain SMS-3-5 / SECEC)	29%	100%
B1WC61	Rattus norvegicus	33%	82%
B1XBG4	Escherichia coli (strain K12 / DH10B)	29%	100%
B2AM55	Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383)	27%	100%
B2CML6	Mycobacterium goodii	23%	100%
B4EY23	Proteus mirabilis (strain HI4320)	29%	100%
B4T6J8	Salmonella newport (strain SL254)	28%	100%
B4TIH2	Salmonella heidelberg (strain SL476)	28%	100%
B4TWR6	Salmonella schwarzengrund (strain CVM19633)	28%	100%
B5BL57	Salmonella paratyphi A (strain AKU_12601)	28%	100%
B5F752	Salmonella agona (strain SL483)	28%	100%
B5FHG7	Salmonella dublin (strain CT_02021853)	28%	100%
B5R1R2	Salmonella enteritidis PT4 (strain P125109)	28%	100%
B5RGA6	Salmonella gallinarum (strain 287/91 / NCTC 13346)	28%	100%
B5YYD3	Escherichia coli O157:H7 (strain EC4115 / EHEC)	29%	100%
B6HYZ0	Escherichia coli (strain SE11)	29%	100%
B7L4G2	Escherichia coli (strain 55989 / EAEC)	29%	100%
B7LWN0	Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)	29%	100%
B7M0D6	Escherichia coli O8 (strain IAI1)	29%	100%
B7MAG2	Escherichia coli O45:K1 (strain S88 / ExPEC)	29%	100%
B7MNP6	Escherichia coli O81 (strain ED1a)	29%	100%
B7N7R4	Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)	29%	100%
B7NHE3	Escherichia coli O7:K1 (strain IAI39 / ExPEC)	29%	100%
B7UI85	Escherichia coli O127:H6 (strain E2348/69 / EPEC)	29%	100%
B9U6P5	Variovorax paradoxus	32%	100%
C0Q4L5	Salmonella paratyphi C (strain RKS4594)	28%	100%
C3UVB0	Desulfococcus multivorans	35%	100%
C4ZPW5	Escherichia coli (strain K12 / MC4100 / BW2952)	29%	100%
D0A5U7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
D3JV03	Cereibacter sphaeroides	34%	93%
E9AD70	Leishmania major	32%	100%
E9AF97	Leishmania major	35%	100%
E9AKW6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%
E9AYZ5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
E9B073	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	81%
E9B6F2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
F8GVD3	Cupriavidus necator (strain ATCC 43291 / DSM 13513 / CCUG 52238 / LMG 8453 / N-1)	32%	100%
G3KIM8	Anaerotignum propionicum	35%	100%
H6LGM6	Acetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655 / WB1)	38%	100%
I6Y3V5	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	27%	100%
I6YCA3	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	26%	100%
J7TF92	Clostridium sporogenes (strain ATCC 15579)	37%	100%
K4L7X3	Advenella mimigardefordensis (strain DSM 17166 / LMG 22922 / DPN7)	30%	100%
O32176	Bacillus subtilis (strain 168)	30%	86%
O34421	Bacillus subtilis (strain 168)	37%	100%
O54143	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	32%	100%
P08503	Rattus norvegicus	59%	100%
P0A9U8	Escherichia coli (strain K12)	28%	100%
P0A9U9	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	28%	100%
P0A9V0	Escherichia coli O157:H7	28%	100%
P11310	Homo sapiens	61%	100%
P12007	Rattus norvegicus	31%	100%
P15650	Rattus norvegicus	29%	100%
P15651	Rattus norvegicus	37%	100%
P16219	Homo sapiens	36%	100%
P26440	Homo sapiens	31%	100%
P28330	Homo sapiens	29%	100%
P34275	Caenorhabditis elegans	32%	100%
P41367	Sus scrofa	59%	100%
P45857	Bacillus subtilis (strain 168)	37%	100%
P45867	Bacillus subtilis (strain 168)	42%	100%
P45952	Mus musculus	59%	100%
P45953	Rattus norvegicus	29%	78%
P45954	Homo sapiens	34%	100%
P46703	Mycobacterium leprae (strain TN)	37%	100%
P48818	Bos taurus	30%	78%
P49748	Homo sapiens	30%	78%
P50544	Mus musculus	31%	78%
P51174	Mus musculus	29%	100%
P52042	Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)	38%	100%
P54998	Rhodococcus sp. (strain ATCC 53968 / IGTS8)	23%	100%
P60584	Escherichia coli (strain K12)	29%	100%
P60585	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	29%	100%
P60586	Escherichia coli O157:H7	29%	100%
P60587	Shigella flexneri	29%	100%
P63428	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	39%	100%
P63430	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	30%	79%
P70584	Rattus norvegicus	35%	100%
P71858	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	24%	100%
P79273	Sus scrofa	35%	100%
P79274	Sus scrofa	30%	100%
P81140	Sus scrofa	28%	100%
P95280	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	27%	100%
P96608	Bacillus subtilis (strain 168)	24%	100%
P96831	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	23%	100%
P96855	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	26%	72%
P9WQF6	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	30%	79%
P9WQF7	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	30%	79%
P9WQG0	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	39%	100%
P9WQG1	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	39%	100%
P9WQG2	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	31%	100%
P9WQG3	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	31%	100%
Q06319	Megasphaera elsdenii	39%	100%
Q07417	Mus musculus	37%	100%
Q0NXR6	Bos taurus	32%	100%
Q0T8F5	Shigella flexneri serotype 5b (strain 8401)	29%	100%
Q0TLV0	Escherichia coli O6:K15:H31 (strain 536 / UPEC)	29%	100%
Q13PC1	Paraburkholderia xenovorans (strain LB400)	35%	100%
Q1BBA3	Mycobacterium sp. (strain MCS)	25%	100%
Q1RGF9	Escherichia coli (strain UTI89 / UPEC)	29%	100%
Q20772	Caenorhabditis elegans	28%	100%
Q22347	Caenorhabditis elegans	53%	100%
Q2KHZ9	Bos taurus	29%	100%
Q2LQN9	Syntrophus aciditrophicus (strain SB)	37%	100%
Q2LQP0	Syntrophus aciditrophicus (strain SB)	39%	100%
Q32K58	Shigella dysenteriae serotype 1 (strain Sd197)	29%	100%
Q3SZB4	Bos taurus	59%	100%
Q3SZI8	Bos taurus	31%	100%
Q3Z5W9	Shigella sonnei (strain Ss046)	29%	100%
Q3ZBF6	Bos taurus	36%	100%
Q4KCY6	Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)	28%	100%
Q4Q812	Leishmania major	27%	81%
Q4QIY9	Leishmania major	88%	100%
Q50LG2	Alternaria alternata	30%	100%
Q54IM8	Dictyostelium discoideum	34%	100%
Q54R47	Dictyostelium discoideum	29%	100%
Q54RR5	Dictyostelium discoideum	33%	100%
Q57TI8	Salmonella choleraesuis (strain SC-B67)	28%	100%
Q5ATG5	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	27%	100%
Q5EAD4	Bos taurus	34%	100%
Q5LLW7	Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)	29%	87%
Q5PIN6	Salmonella paratyphi A (strain ATCC 9150 / SARB42)	28%	100%
Q5RAS0	Pongo abelii	36%	100%
Q5RBD5	Pongo abelii	32%	100%
Q5RF40	Pongo abelii	34%	100%
Q5W271	Serratia sp. (strain ATCC 39006)	26%	100%
Q60759	Mus musculus	28%	100%
Q60HI0	Macaca fascicularis	29%	100%
Q6WNP1	Rhodococcus erythropolis (strain XP)	23%	100%
Q75IM9	Oryza sativa subsp. japonica	36%	100%
Q7U0Y2	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	31%	100%
Q8GB20	Proteus sp. (strain LE138)	29%	100%
Q8HXX8	Macaca fascicularis	29%	100%
Q8HXY7	Macaca fascicularis	33%	78%
Q8HXY8	Macaca fascicularis	59%	100%
Q8JZN5	Mus musculus	33%	82%
Q8X1D8	Fusarium oxysporum	24%	100%
Q8Z9L2	Salmonella typhi	28%	100%
Q8ZRX2	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	28%	100%
Q92947	Homo sapiens	28%	100%
Q96329	Arabidopsis thaliana	30%	100%
Q9D7B6	Mus musculus	32%	100%
Q9DBL1	Mus musculus	34%	100%
Q9FS87	Solanum tuberosum	33%	100%
Q9FS88	Solanum tuberosum	34%	100%
Q9H845	Homo sapiens	34%	82%
Q9JHI5	Mus musculus	31%	100%
Q9KJE8	Thauera aromatica	28%	100%
Q9SWG0	Arabidopsis thaliana	33%	100%
Q9UKU7	Homo sapiens	32%	100%
Q9VSA3	Drosophila melanogaster	60%	100%
V5B8K6	Trypanosoma cruzi	32%	100%
V5BKL8	Trypanosoma cruzi	28%	100%
V5BY79	Trypanosoma cruzi	34%	100%
V5DCV2	Trypanosoma cruzi	27%	82%
V5DPQ5	Trypanosoma cruzi	64%	100%