Putative 60S ribosomal protein L19

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

60S ribosomal protein L19, putative

Species:

Leishmania braziliensis

UniProt:

A4H4K8_LEIBR

TriTrypDb:

LbrM.06.0410

Length:

176

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0015934	large ribosomal subunit	4	2
GO:0022625	cytosolic large ribosomal subunit	5	2
GO:0032991	protein-containing complex	1	2
GO:0044391	ribosomal subunit	3	2
GO:1990904	ribonucleoprotein complex	2	2

Expansion

Sequence features

A4H4K8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H4K8

Function

Biological processes
Term	Name	Level	Count
GO:0006412	translation	4	2
GO:0006518	peptide metabolic process	4	2
GO:0006807	nitrogen compound metabolic process	2	2
GO:0008152	metabolic process	1	2
GO:0009058	biosynthetic process	2	2
GO:0009059	macromolecule biosynthetic process	4	2
GO:0009987	cellular process	1	2
GO:0019538	protein metabolic process	3	2
GO:0034641	cellular nitrogen compound metabolic process	3	2
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	2
GO:0043043	peptide biosynthetic process	5	2
GO:0043170	macromolecule metabolic process	3	2
GO:0043603	amide metabolic process	3	2
GO:0043604	amide biosynthetic process	4	2
GO:0044237	cellular metabolic process	2	2
GO:0044238	primary metabolic process	2	2
GO:0044249	cellular biosynthetic process	3	2
GO:0044260	obsolete cellular macromolecule metabolic process	3	2
GO:0044271	cellular nitrogen compound biosynthetic process	4	2
GO:0071704	organic substance metabolic process	2	2
GO:1901564	organonitrogen compound metabolic process	3	2
GO:1901566	organonitrogen compound biosynthetic process	4	2
GO:1901576	organic substance biosynthetic process	3	2

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	2
GO:0003723	RNA binding	4	2
GO:0003735	structural constituent of ribosome	2	2
GO:0005198	structural molecule activity	1	2
GO:0005488	binding	1	2
GO:0097159	organic cyclic compound binding	2	2
GO:1901363	heterocyclic compound binding	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	11	13	PF00675	0.392
CLV_NRD_NRD_1	2	4	PF00675	0.549
CLV_NRD_NRD_1	78	80	PF00675	0.743
CLV_NRD_NRD_1	8	10	PF00675	0.444
CLV_NRD_NRD_1	94	96	PF00675	0.464
CLV_PCSK_FUR_1	38	42	PF00082	0.549
CLV_PCSK_FUR_1	92	96	PF00082	0.738
CLV_PCSK_KEX2_1	2	4	PF00082	0.549
CLV_PCSK_KEX2_1	40	42	PF00082	0.549
CLV_PCSK_KEX2_1	8	10	PF00082	0.444
CLV_PCSK_KEX2_1	85	87	PF00082	0.741
CLV_PCSK_KEX2_1	94	96	PF00082	0.587
CLV_PCSK_PC1ET2_1	40	42	PF00082	0.549
CLV_PCSK_PC1ET2_1	85	87	PF00082	0.741
CLV_PCSK_PC7_1	90	96	PF00082	0.737
CLV_PCSK_SKI1_1	8	12	PF00082	0.549
DEG_Nend_UBRbox_1	1	4	PF02207	0.549
DOC_USP7_MATH_1	110	114	PF00917	0.805
DOC_USP7_MATH_1	121	125	PF00917	0.653
DOC_USP7_MATH_1	129	133	PF00917	0.503
DOC_USP7_MATH_1	137	141	PF00917	0.547
DOC_USP7_MATH_1	171	175	PF00917	0.841
DOC_USP7_UBL2_3	172	176	PF12436	0.845
DOC_USP7_UBL2_3	51	55	PF12436	0.705
DOC_USP7_UBL2_3	80	84	PF12436	0.742
LIG_NRBOX	6	12	PF00104	0.549
LIG_SH2_STAT5	29	32	PF00017	0.549
LIG_SH3_2	154	159	PF14604	0.843
LIG_SH3_3	151	157	PF00018	0.841
LIG_UBA3_1	43	51	PF00899	0.549
LIG_UBA3_1	6	13	PF00899	0.549
MOD_GlcNHglycan	112	115	PF01048	0.819
MOD_GlcNHglycan	123	126	PF01048	0.653
MOD_GlcNHglycan	131	134	PF01048	0.502
MOD_SUMO_for_1	50	53	PF00179	0.697
TRG_DiLeu_BaLyEn_6	6	11	PF01217	0.549
TRG_ENDOCYTIC_2	25	28	PF00928	0.549
TRG_ER_diArg_1	1	3	PF00400	0.549
TRG_ER_diArg_1	7	9	PF00400	0.444
TRG_ER_diArg_1	92	95	PF00400	0.738
TRG_ER_diLys_1	172	176	PF00400	0.845
TRG_NLS_Bipartite_1	2	16	PF00514	0.549
TRG_NLS_MonoExtC_3	11	17	PF00514	0.549
TRG_NLS_MonoExtC_3	171	176	PF00514	0.845
TRG_NLS_MonoExtN_4	170	176	PF00514	0.843
TRG_NLS_MonoExtN_4	9	16	PF00514	0.549
TRG_Pf-PMV_PEXEL_1	41	45	PF00026	0.549
TRG_Pf-PMV_PEXEL_1	58	62	PF00026	0.422

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A1D8PK40	CANAL	51%	93%
D0VWQ5	CANLF	43%	90%
O02639	CAEEL	51%	89%
O42699	SCHPO	49%	91%
O59437	PYRHO	60%	100%
P05734	SCHPO	49%	91%
P0CX82	YEAST	47%	93%
P0CX83	YEAST	47%	93%
P14329	DICDI	52%	95%
P36241	DROME	61%	87%
P49693	ARATH	61%	85%
P84098	HUMAN	43%	90%
P84099	MOUSE	43%	90%
P84100	RAT	43%	90%
Q3T0W9	BOVIN	43%	90%
Q5RB99	PONAB	43%	90%
Q6P5L3	DANRE	67%	90%
Q7ZYS1	XENLA	43%	89%
Q8HXN9	MACFA	43%	90%
Q8U016	PYRFU	56%	100%
Q90YU8	ICTPU	63%	90%
Q9LUQ6	ARATH	56%	84%
Q9SRX2	ARATH	52%	82%