MYND finger domain-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

MYND finger domain-like protein

Species:

Leishmania braziliensis

UniProt:

A4H4J6_LEIBR

TriTrypDb:

LbrM.06.0280 , LBRM2903_060008400

Length:

180

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H4J6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H4J6

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	7
GO:0043167	ion binding	2	7
GO:0043169	cation binding	3	7
GO:0046872	metal ion binding	4	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	49	53	PF00656	0.304
CLV_NRD_NRD_1	30	32	PF00675	0.354
CLV_PCSK_KEX2_1	23	25	PF00082	0.375
CLV_PCSK_KEX2_1	30	32	PF00082	0.337
CLV_PCSK_PC1ET2_1	23	25	PF00082	0.375
CLV_PCSK_SKI1_1	153	157	PF00082	0.325
DEG_SPOP_SBC_1	138	142	PF00917	0.286
DOC_CKS1_1	173	178	PF01111	0.377
DOC_USP7_MATH_1	98	102	PF00917	0.298
DOC_USP7_UBL2_3	164	168	PF12436	0.383
DOC_WW_Pin1_4	114	119	PF00397	0.510
DOC_WW_Pin1_4	172	177	PF00397	0.451
LIG_Clathr_ClatBox_1	103	107	PF01394	0.498
LIG_FHA_1	139	145	PF00498	0.326
LIG_FHA_1	62	68	PF00498	0.385
LIG_FHA_2	17	23	PF00498	0.308
LIG_FHA_2	41	47	PF00498	0.456
LIG_FHA_2	7	13	PF00498	0.293
LIG_Pex14_2	73	77	PF04695	0.497
LIG_SH2_STAT5	102	105	PF00017	0.492
LIG_SH2_STAT5	157	160	PF00017	0.328
LIG_SH3_3	170	176	PF00018	0.363
LIG_TRAF2_1	36	39	PF00917	0.466
LIG_WW_3	77	81	PF00397	0.405
MOD_CK1_1	130	136	PF00069	0.221
MOD_CK2_1	40	46	PF00069	0.453
MOD_CK2_1	6	12	PF00069	0.286
MOD_CK2_1	89	95	PF00069	0.311
MOD_GlcNHglycan	129	132	PF01048	0.221
MOD_N-GLC_1	89	94	PF02516	0.305
MOD_N-GLC_2	119	121	PF02516	0.396
MOD_NEK2_1	15	20	PF00069	0.571
MOD_NEK2_1	54	59	PF00069	0.402
MOD_NEK2_1	73	78	PF00069	0.507
MOD_PIKK_1	22	28	PF00454	0.635
MOD_PK_1	156	162	PF00069	0.383
MOD_PKA_2	147	153	PF00069	0.381
MOD_Plk_1	107	113	PF00069	0.354
MOD_Plk_4	40	46	PF00069	0.393
MOD_Plk_4	67	73	PF00069	0.447
MOD_Plk_4	98	104	PF00069	0.399
MOD_ProDKin_1	114	120	PF00069	0.499
MOD_ProDKin_1	172	178	PF00069	0.378
MOD_SUMO_rev_2	161	169	PF00179	0.383
TRG_DiLeu_BaLyEn_6	62	67	PF01217	0.425
TRG_ENDOCYTIC_2	157	160	PF00928	0.383
TRG_ER_diArg_1	29	31	PF00400	0.361

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IL36	Leptomonas seymouri	74%	100%
A0A0S4JPC0	Bodo saltans	37%	100%
A0A3S5H5P3	Leishmania donovani	83%	100%
A4HSS1	Leishmania infantum	83%	100%
E9AKQ8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	100%
Q4QJ49	Leishmania major	81%	94%