SBF2 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania braziliensis

UniProt:

A4H4F0_LEIBR

TriTrypDb:

LbrM.05.1050 , LBRM2903_050016500

Length:

517

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H4F0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H4F0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	168	172	PF00656	0.668
CLV_NRD_NRD_1	213	215	PF00675	0.554
CLV_NRD_NRD_1	229	231	PF00675	0.560
CLV_NRD_NRD_1	365	367	PF00675	0.499
CLV_NRD_NRD_1	429	431	PF00675	0.542
CLV_NRD_NRD_1	436	438	PF00675	0.584
CLV_NRD_NRD_1	500	502	PF00675	0.570
CLV_PCSK_KEX2_1	212	214	PF00082	0.563
CLV_PCSK_KEX2_1	229	231	PF00082	0.560
CLV_PCSK_KEX2_1	364	366	PF00082	0.500
CLV_PCSK_KEX2_1	429	431	PF00082	0.542
CLV_PCSK_KEX2_1	436	438	PF00082	0.584
CLV_PCSK_KEX2_1	500	502	PF00082	0.570
CLV_PCSK_PC1ET2_1	212	214	PF00082	0.563
CLV_PCSK_PC1ET2_1	364	366	PF00082	0.527
CLV_PCSK_SKI1_1	148	152	PF00082	0.651
CLV_PCSK_SKI1_1	421	425	PF00082	0.532
CLV_PCSK_SKI1_1	446	450	PF00082	0.629
CLV_PCSK_SKI1_1	492	496	PF00082	0.583
CLV_PCSK_SKI1_1	73	77	PF00082	0.587
CLV_PCSK_SKI1_1	85	89	PF00082	0.745
DOC_ANK_TNKS_1	402	409	PF00023	0.625
DOC_CYCLIN_RxL_1	148	158	PF00134	0.707
DOC_PP1_SILK_1	177	182	PF00149	0.519
DOC_PP2B_LxvP_1	81	84	PF13499	0.772
DOC_USP7_MATH_1	182	186	PF00917	0.721
DOC_USP7_MATH_1	406	410	PF00917	0.615
DOC_WW_Pin1_4	12	17	PF00397	0.488
DOC_WW_Pin1_4	504	509	PF00397	0.486
DOC_WW_Pin1_4	52	57	PF00397	0.486
LIG_14-3-3_CanoR_1	124	134	PF00244	0.810
LIG_14-3-3_CanoR_1	213	221	PF00244	0.433
LIG_14-3-3_CanoR_1	365	370	PF00244	0.582
LIG_14-3-3_CanoR_1	391	400	PF00244	0.523
LIG_14-3-3_CanoR_1	403	411	PF00244	0.514
LIG_14-3-3_CanoR_1	437	443	PF00244	0.548
LIG_Actin_WH2_2	483	499	PF00022	0.581
LIG_APCC_ABBA_1	268	273	PF00400	0.436
LIG_APCC_ABBA_1	445	450	PF00400	0.682
LIG_BIR_II_1	1	5	PF00653	0.504
LIG_BRCT_BRCA1_1	42	46	PF00533	0.501
LIG_BRCT_BRCA1_1	59	63	PF00533	0.464
LIG_CtBP_PxDLS_1	106	110	PF00389	0.568
LIG_deltaCOP1_diTrp_1	407	415	PF00928	0.514
LIG_FHA_1	140	146	PF00498	0.537
LIG_FHA_1	174	180	PF00498	0.756
LIG_FHA_1	216	222	PF00498	0.397
LIG_FHA_1	489	495	PF00498	0.579
LIG_FHA_1	60	66	PF00498	0.512
LIG_FHA_1	76	82	PF00498	0.716
LIG_FHA_1	88	94	PF00498	0.616
LIG_FHA_2	190	196	PF00498	0.608
LIG_FHA_2	262	268	PF00498	0.530
LIG_FHA_2	319	325	PF00498	0.728
LIG_FHA_2	475	481	PF00498	0.692
LIG_LIR_Gen_1	185	194	PF02991	0.583
LIG_LIR_Gen_1	348	359	PF02991	0.608
LIG_LIR_Gen_1	368	378	PF02991	0.273
LIG_LIR_Nem_3	185	190	PF02991	0.558
LIG_LIR_Nem_3	348	354	PF02991	0.614
LIG_LIR_Nem_3	368	373	PF02991	0.271
LIG_LIR_Nem_3	505	509	PF02991	0.731
LIG_NRBOX	149	155	PF00104	0.706
LIG_PCNA_yPIPBox_3	141	154	PF02747	0.634
LIG_PCNA_yPIPBox_3	197	210	PF02747	0.556
LIG_Pex14_2	29	33	PF04695	0.495
LIG_Pex14_2	63	67	PF04695	0.459
LIG_REV1ctd_RIR_1	65	75	PF16727	0.464
LIG_SH2_GRB2like	277	280	PF00017	0.555
LIG_SH2_STAP1	217	221	PF00017	0.420
LIG_SH2_STAP1	266	270	PF00017	0.538
LIG_SH2_STAP1	351	355	PF00017	0.500
LIG_SH2_STAP1	370	374	PF00017	0.266
LIG_SH2_STAP1	400	404	PF00017	0.523
LIG_SH2_STAP1	427	431	PF00017	0.534
LIG_SH2_STAT3	343	346	PF00017	0.534
LIG_SH2_STAT5	217	220	PF00017	0.399
LIG_SH2_STAT5	343	346	PF00017	0.534
LIG_SH2_STAT5	506	509	PF00017	0.494
LIG_SH3_1	10	16	PF00018	0.490
LIG_SH3_3	10	16	PF00018	0.605
LIG_SUMO_SIM_par_1	130	135	PF11976	0.574
LIG_SxIP_EBH_1	10	23	PF03271	0.490
LIG_WRC_WIRS_1	64	69	PF05994	0.460
MOD_CK1_1	125	131	PF00069	0.711
MOD_CK1_1	34	40	PF00069	0.680
MOD_CK1_1	465	471	PF00069	0.689
MOD_CK1_1	55	61	PF00069	0.578
MOD_CK2_1	182	188	PF00069	0.613
MOD_CK2_1	189	195	PF00069	0.578
MOD_CK2_1	261	267	PF00069	0.526
MOD_CK2_1	365	371	PF00069	0.526
MOD_CK2_1	507	513	PF00069	0.676
MOD_GlcNHglycan	114	118	PF01048	0.677
MOD_GlcNHglycan	157	160	PF01048	0.702
MOD_GlcNHglycan	381	384	PF01048	0.365
MOD_GlcNHglycan	42	45	PF01048	0.562
MOD_GlcNHglycan	59	62	PF01048	0.674
MOD_GlcNHglycan	90	93	PF01048	0.742
MOD_GSK3_1	109	116	PF00069	0.711
MOD_GSK3_1	31	38	PF00069	0.495
MOD_GSK3_1	402	409	PF00069	0.492
MOD_GSK3_1	55	62	PF00069	0.557
MOD_GSK3_1	88	95	PF00069	0.801
MOD_N-GLC_1	290	295	PF02516	0.489
MOD_N-GLC_1	34	39	PF02516	0.497
MOD_N-GLC_2	420	422	PF02516	0.535
MOD_NEK2_1	122	127	PF00069	0.751
MOD_NEK2_1	153	158	PF00069	0.714
MOD_NEK2_1	180	185	PF00069	0.744
MOD_NEK2_1	423	428	PF00069	0.636
MOD_NEK2_1	57	62	PF00069	0.496
MOD_NEK2_1	63	68	PF00069	0.546
MOD_NEK2_1	69	74	PF00069	0.720
MOD_NEK2_1	75	80	PF00069	0.709
MOD_NEK2_2	182	187	PF00069	0.614
MOD_PIKK_1	125	131	PF00454	0.565
MOD_PIKK_1	215	221	PF00454	0.396
MOD_PIKK_1	391	397	PF00454	0.536
MOD_PK_1	290	296	PF00069	0.495
MOD_PKA_1	212	218	PF00069	0.405
MOD_PKA_1	365	371	PF00069	0.604
MOD_PKA_2	123	129	PF00069	0.808
MOD_PKA_2	137	143	PF00069	0.712
MOD_PKA_2	180	186	PF00069	0.637
MOD_PKA_2	212	218	PF00069	0.405
MOD_PKA_2	261	267	PF00069	0.526
MOD_PKA_2	365	371	PF00069	0.592
MOD_PKA_2	379	385	PF00069	0.556
MOD_PKA_2	402	408	PF00069	0.539
MOD_PKA_2	76	82	PF00069	0.755
MOD_Plk_1	290	296	PF00069	0.495
MOD_Plk_1	318	324	PF00069	0.648
MOD_Plk_1	462	468	PF00069	0.703
MOD_Plk_4	182	188	PF00069	0.613
MOD_Plk_4	365	371	PF00069	0.604
MOD_Plk_4	37	43	PF00069	0.496
MOD_Plk_4	406	412	PF00069	0.543
MOD_Plk_4	474	480	PF00069	0.627
MOD_Plk_4	59	65	PF00069	0.463
MOD_ProDKin_1	12	18	PF00069	0.487
MOD_ProDKin_1	504	510	PF00069	0.492
MOD_ProDKin_1	52	58	PF00069	0.486
MOD_SUMO_rev_2	226	235	PF00179	0.551
TRG_DiLeu_BaEn_2	204	210	PF01217	0.643
TRG_DiLeu_BaLyEn_6	128	133	PF01217	0.573
TRG_ENDOCYTIC_2	351	354	PF00928	0.607
TRG_ENDOCYTIC_2	370	373	PF00928	0.268
TRG_ER_diArg_1	228	230	PF00400	0.587
TRG_ER_diArg_1	25	28	PF00400	0.741
TRG_ER_diArg_1	284	287	PF00400	0.689
TRG_ER_diArg_1	436	438	PF00400	0.584
TRG_ER_diArg_1	500	502	PF00400	0.570
TRG_NLS_MonoCore_2	363	368	PF00514	0.609
TRG_Pf-PMV_PEXEL_1	148	152	PF00026	0.714
TRG_Pf-PMV_PEXEL_1	197	201	PF00026	0.574

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3V2	Leptomonas seymouri	65%	100%
A0A3S5H5L5	Leishmania donovani	86%	100%
A4HSM7	Leishmania infantum	86%	100%
E9AKL1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%
Q4QJ97	Leishmania major	84%	100%