Stomatin-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

stomatin-like protein

Species:

Leishmania braziliensis

UniProt:

A4H4E9_LEIBR

TriTrypDb:

LbrM.05.1040 , LBRM2903_050016400

Length:

358

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Show entries

Cellular components
Term	Name	Level	Count
GO:0005739	mitochondrion	5	1
GO:0005886	plasma membrane	3	1
GO:0016020	membrane	2	12
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	12

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Expansion

Sequence features

A4H4E9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H4E9

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	187	189	PF00675	0.289
CLV_NRD_NRD_1	212	214	PF00675	0.260
CLV_NRD_NRD_1	222	224	PF00675	0.232
CLV_NRD_NRD_1	225	227	PF00675	0.226
CLV_NRD_NRD_1	4	6	PF00675	0.490
CLV_PCSK_FUR_1	223	227	PF00082	0.243
CLV_PCSK_KEX2_1	187	189	PF00082	0.271
CLV_PCSK_KEX2_1	198	200	PF00082	0.176
CLV_PCSK_KEX2_1	212	214	PF00082	0.243
CLV_PCSK_KEX2_1	225	227	PF00082	0.226

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HTU5	Leptomonas seymouri	84%	99%
A0A0S4INS2	Bodo saltans	61%	100%
A0A1X0NKE1	Trypanosomatidae	68%	84%
A0A3R7M6V7	Trypanosoma rangeli	62%	93%
A0A3S5H5L4	Leishmania donovani	93%	100%
A4HSM6	Leishmania infantum	93%	100%
C9ZND8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	66%	67%
E9AKL0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
E9AS80	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
O60121	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	46%	100%

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