LeishMANIAdb
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BBE domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
BBE domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4H4E7_LEIBR
TriTrypDb:
LbrM.05.1020 , LBRM2903_050016200 *
Length:
847

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
TermNameLevelCount
GO:0005730 nucleolus 5 1
GO:0005856 cytoskeleton 5 1
GO:0005929 cilium 4 2
GO:0031514 motile cilium 5 2
GO:0042995 cell projection 2 2
GO:0043226 organelle 2 2
GO:0043227 membrane-bounded organelle 3 2
GO:0043228 non-membrane-bounded organelle 3 2
GO:0043229 intracellular organelle 3 2
GO:0043232 intracellular non-membrane-bounded organelle 4 2
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Expansion

Sequence features

A4H4E7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H4E7

Function

Biological processes
TermNameLevelCount
GO:0009987 cellular process 1 1
GO:0048870 cell motility 2 1
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Could not find GO molecular_function term for this entry.

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 155 159 PF00656 0.649
CLV_C14_Caspase3-7 215 219 PF00656 0.509
CLV_C14_Caspase3-7 301 305 PF00656 0.442
CLV_NRD_NRD_1 195 197 PF00675 0.417
CLV_NRD_NRD_1 281 283 PF00675 0.605
CLV_NRD_NRD_1 308 310 PF00675 0.609
CLV_NRD_NRD_1 386 388 PF00675 0.403
CLV_NRD_NRD_1 422 424 PF00675 0.487
CLV_NRD_NRD_1 478 480 PF00675 0.416
CLV_NRD_NRD_1 638 640 PF00675 0.368
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I0W5 Leptomonas seymouri 67% 93%
A0A0S4JUW0 Bodo saltans 43% 98%
A0A1X0NLT5 Trypanosomatidae 43% 87%
A0A3R7LNV4 Trypanosoma rangeli 44% 87%
A0A3S7WP94 Leishmania donovani 85% 92%
A4HSM4 Leishmania infantum 85% 92%
E9AKK8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 83% 92%
G2HE57 Pan troglodytes 27% 97%
Q0V9S9 Xenopus tropicalis 27% 99%
Q2T9M4 Bos taurus 27% 97%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS