LeishMANIAdb
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RING-type domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
RING-type domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4H4E5_LEIBR
TriTrypDb:
LbrM.05.1000 , LBRM2903_050016000
Length:
104

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H4E5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H4E5

Putative motif mimicry

Leishmania From To Domain/Motif Score
DEG_Nend_UBRbox_2 1 3 PF02207 0.670
DOC_CYCLIN_yCln2_LP_2 42 45 PF00134 0.539
DOC_PP2B_LxvP_1 42 45 PF13499 0.604
DOC_PP2B_LxvP_1 61 64 PF13499 0.405
LIG_Pex14_2 69 73 PF04695 0.368
LIG_SH3_3 38 44 PF00018 0.537
LIG_SH3_3 60 66 PF00018 0.327
MOD_CK1_1 23 29 PF00069 0.458
MOD_CK1_1 7 13 PF00069 0.532
MOD_NEK2_1 98 103 PF00069 0.369

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HVG8 Leptomonas seymouri 74% 98%
A0A3S7WP79 Leishmania donovani 78% 100%
A4HSM2 Leishmania infantum 77% 100%
E9AKK6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 76% 100%
Q4QJA2 Leishmania major 74% 99%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS