LeishMANIAdb
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ATPase alpha subunit

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
ATPase alpha subunit
Gene product:
ATP synthase F1, alpha subunit, putative (fragment)
Species:
Leishmania braziliensis
UniProt:
A4H496_LEIBR
TriTrypDb:
LbrM.05.0510 , LBRM2903_050010200 *
Length:
237

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 5
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H496
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H496

Function

Biological processes
TermNameLevelCount
GO:0006139 nucleobase-containing compound metabolic process 3 2
GO:0006163 purine nucleotide metabolic process 5 2
GO:0006164 purine nucleotide biosynthetic process 6 2
GO:0006725 cellular aromatic compound metabolic process 3 2
GO:0006753 nucleoside phosphate metabolic process 4 2
GO:0006754 ATP biosynthetic process 8 2
GO:0006793 phosphorus metabolic process 3 2
GO:0006796 phosphate-containing compound metabolic process 4 2
GO:0006807 nitrogen compound metabolic process 2 2
GO:0006810 transport 3 2
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Molecular functions
TermNameLevelCount
GO:0000166 nucleotide binding 3 2
GO:0005488 binding 1 2
GO:0005524 ATP binding 5 2
GO:0017076 purine nucleotide binding 4 2
GO:0030554 adenyl nucleotide binding 5 2
GO:0032553 ribonucleotide binding 3 2
GO:0032555 purine ribonucleotide binding 4 2
GO:0032559 adenyl ribonucleotide binding 5 2
GO:0035639 purine ribonucleoside triphosphate binding 4 2
GO:0036094 small molecule binding 2 2
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 34 38 PF00656 0.600
CLV_NRD_NRD_1 87 89 PF00675 0.600
CLV_PCSK_KEX2_1 234 236 PF00082 0.820
CLV_PCSK_PC1ET2_1 234 236 PF00082 0.820
CLV_PCSK_SKI1_1 182 186 PF00082 0.836
CLV_PCSK_SKI1_1 221 225 PF00082 0.842
CLV_PCSK_SKI1_1 227 231 PF00082 0.715
CLV_PCSK_SKI1_1 45 49 PF00082 0.600
CLV_PCSK_SKI1_1 81 85 PF00082 0.600
DEG_Nend_Nbox_1 1 3 PF02207 0.812
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Homologs

ProteinTaxonomySequence identityCoverage
A0ALL5 LISW6 51% 47%
A0JY66 ARTS2 50% 43%
A0LDA2 MAGMM 51% 47%
A0LLG0 SYNFM 52% 47%
A0LSL4 ACIC1 53% 43%
A0PUK2 MYCUA 46% 43%
A0Q2Z6 CLONN 52% 47%
A0QCX6 MYCA1 41% 43%
A0R202 MYCS2 46% 43%
A0RR28 CAMFF 49% 47%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS