LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein
Species:
Leishmania braziliensis
UniProt:
A4H442_LEIBR
TriTrypDb:
LbrM.04.1290 , LBRM2903_040012300 *
Length:
1271

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H442
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H442

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 1004 1008 PF00656 0.718
CLV_C14_Caspase3-7 1090 1094 PF00656 0.585
CLV_C14_Caspase3-7 380 384 PF00656 0.575
CLV_C14_Caspase3-7 424 428 PF00656 0.649
CLV_C14_Caspase3-7 614 618 PF00656 0.550
CLV_C14_Caspase3-7 893 897 PF00656 0.395
CLV_NRD_NRD_1 1128 1130 PF00675 0.628
CLV_NRD_NRD_1 1239 1241 PF00675 0.596
CLV_NRD_NRD_1 1256 1258 PF00675 0.552
CLV_NRD_NRD_1 161 163 PF00675 0.583
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3S5H5B6 Leishmania donovani 54% 99%
A4HS57 Leishmania infantum 54% 99%
E9AK44 Leishmania mexicana (strain MHOM/GT/2001/U1103) 52% 100%
Q9NEE0 Leishmania major 53% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS