Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania braziliensis

UniProt:

A4H428_LEIBR

TriTrypDb:

LbrM.04.1150 , LBRM2903_040019100

Length:

303

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H428

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H428

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	32	34	PF00675	0.655
CLV_PCSK_FUR_1	169	173	PF00082	0.411
CLV_PCSK_KEX2_1	14	16	PF00082	0.580
CLV_PCSK_KEX2_1	171	173	PF00082	0.423
CLV_PCSK_PC1ET2_1	14	16	PF00082	0.652
CLV_PCSK_PC1ET2_1	171	173	PF00082	0.423
CLV_Separin_Metazoa	257	261	PF03568	0.551
DEG_SCF_TRCP1_1	269	274	PF00400	0.549
DEG_SPOP_SBC_1	104	108	PF00917	0.547
DOC_PP2B_LxvP_1	291	294	PF13499	0.496
DOC_PP4_FxxP_1	21	24	PF00568	0.438
DOC_USP7_MATH_1	235	239	PF00917	0.806
DOC_USP7_MATH_1	275	279	PF00917	0.708
DOC_USP7_UBL2_3	34	38	PF12436	0.606
DOC_WW_Pin1_4	105	110	PF00397	0.719
DOC_WW_Pin1_4	123	128	PF00397	0.591
DOC_WW_Pin1_4	230	235	PF00397	0.538
DOC_WW_Pin1_4	247	252	PF00397	0.566
DOC_WW_Pin1_4	271	276	PF00397	0.769
LIG_14-3-3_CanoR_1	115	121	PF00244	0.565
LIG_14-3-3_CanoR_1	197	202	PF00244	0.484
LIG_14-3-3_CanoR_1	82	92	PF00244	0.569
LIG_14-3-3_CanoR_1	96	100	PF00244	0.772
LIG_AP2alpha_2	55	57	PF02296	0.573
LIG_BIR_II_1	1	5	PF00653	0.672
LIG_FHA_1	156	162	PF00498	0.476
LIG_FHA_1	225	231	PF00498	0.528
LIG_FHA_2	218	224	PF00498	0.534
LIG_FHA_2	248	254	PF00498	0.555
LIG_LIR_Gen_1	55	64	PF02991	0.735
LIG_LIR_Nem_3	55	60	PF02991	0.723
LIG_SH2_STAP1	93	97	PF00017	0.539
LIG_SH2_STAT3	17	20	PF00017	0.463
LIG_SH3_3	231	237	PF00018	0.557
LIG_SH3_3	253	259	PF00018	0.557
LIG_SH3_3	269	275	PF00018	0.631
LIG_SH3_3	50	56	PF00018	0.621
LIG_SH3_4	34	41	PF00018	0.581
LIG_WW_3	257	261	PF00397	0.551
LIG_WW_3	51	55	PF00397	0.655
MOD_CDK_SPxxK_3	105	112	PF00069	0.714
MOD_CK1_1	108	114	PF00069	0.596
MOD_CK1_1	156	162	PF00069	0.476
MOD_CK1_1	285	291	PF00069	0.625
MOD_CK1_1	3	9	PF00069	0.523
MOD_CK2_1	162	168	PF00069	0.457
MOD_CK2_1	215	221	PF00069	0.530
MOD_CK2_1	247	253	PF00069	0.555
MOD_GlcNHglycan	155	158	PF01048	0.560
MOD_GlcNHglycan	163	167	PF01048	0.516
MOD_GlcNHglycan	217	220	PF01048	0.581
MOD_GlcNHglycan	237	240	PF01048	0.572
MOD_GlcNHglycan	269	272	PF01048	0.674
MOD_GlcNHglycan	287	290	PF01048	0.519
MOD_GlcNHglycan	87	90	PF01048	0.762
MOD_GSK3_1	119	126	PF00069	0.623
MOD_GSK3_1	211	218	PF00069	0.484
MOD_GSK3_1	224	231	PF00069	0.609
MOD_GSK3_1	267	274	PF00069	0.770
MOD_GSK3_1	3	10	PF00069	0.524
MOD_GSK3_1	91	98	PF00069	0.691
MOD_GSK3_1	99	106	PF00069	0.598
MOD_LATS_1	27	33	PF00433	0.604
MOD_NEK2_1	1	6	PF00069	0.556
MOD_NEK2_1	282	287	PF00069	0.601
MOD_NEK2_1	97	102	PF00069	0.581
MOD_PIKK_1	74	80	PF00454	0.699
MOD_PKA_2	114	120	PF00069	0.647
MOD_PKA_2	95	101	PF00069	0.760
MOD_Plk_4	156	162	PF00069	0.476
MOD_Plk_4	197	203	PF00069	0.498
MOD_Plk_4	224	230	PF00069	0.580
MOD_ProDKin_1	105	111	PF00069	0.722
MOD_ProDKin_1	123	129	PF00069	0.591
MOD_ProDKin_1	230	236	PF00069	0.539
MOD_ProDKin_1	247	253	PF00069	0.570
MOD_ProDKin_1	271	277	PF00069	0.768
TRG_ER_diArg_1	202	205	PF00400	0.497
TRG_ER_FFAT_2	149	159	PF00635	0.482

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIT4	Leptomonas seymouri	33%	94%
A0A3S5H5F0	Leishmania donovani	56%	100%
A4HSB2	Leishmania infantum	55%	100%
E9AK95	Leishmania mexicana (strain MHOM/GT/2001/U1103)	56%	85%
O97195	Leishmania major	58%	99%