LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4H404_LEIBR
TriTrypDb:
LbrM.04.0900 , LBRM2903_040013200 *
Length:
1063

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 5
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H404
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H404

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 1022 1026 PF00656 0.684
CLV_C14_Caspase3-7 424 428 PF00656 0.534
CLV_C14_Caspase3-7 781 785 PF00656 0.549
CLV_NRD_NRD_1 100 102 PF00675 0.599
CLV_NRD_NRD_1 1027 1029 PF00675 0.560
CLV_NRD_NRD_1 1046 1048 PF00675 0.689
CLV_NRD_NRD_1 1061 1063 PF00675 0.554
CLV_NRD_NRD_1 145 147 PF00675 0.679
CLV_NRD_NRD_1 187 189 PF00675 0.619
CLV_NRD_NRD_1 272 274 PF00675 0.698
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1HZU1 Leptomonas seymouri 32% 100%
A0A3S7WNS9 Leishmania donovani 64% 97%
A4HS66 Leishmania infantum 65% 100%
E9AK53 Leishmania mexicana (strain MHOM/GT/2001/U1103) 62% 99%
Q9NED2 Leishmania major 63% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS