Putative heat shock protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

heat shock protein, putative

Species:

Leishmania braziliensis

UniProt:

A4H3Z0_LEIBR

TriTrypDb:

LbrM.04.0760 , LBRM2903_040013900

Length:

594

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	9
GO:0020016	ciliary pocket	2	1
GO:0110165	cellular anatomical entity	1	9

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Expansion

Sequence features

A4H3Z0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H3Z0

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	260	264	PF00656	0.411
CLV_NRD_NRD_1	158	160	PF00675	0.333
CLV_NRD_NRD_1	30	32	PF00675	0.331
CLV_NRD_NRD_1	409	411	PF00675	0.508
CLV_PCSK_KEX2_1	158	160	PF00082	0.310
CLV_PCSK_KEX2_1	30	32	PF00082	0.330
CLV_PCSK_KEX2_1	409	411	PF00082	0.511
CLV_PCSK_KEX2_1	448	450	PF00082	0.709
CLV_PCSK_PC1ET2_1	448	450	PF00082	0.709
CLV_PCSK_SKI1_1	170	174	PF00082	0.444

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2R3	Leptomonas seymouri	49%	100%
A0A3R7M9P3	Trypanosoma rangeli	26%	100%
A0A3S7WNV0	Leishmania donovani	72%	100%
A4HS75	Leishmania infantum	73%	100%
C9ZY69	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
E9AK61	Leishmania mexicana (strain MHOM/GT/2001/U1103)	68%	100%
O97211	Leishmania major	72%	96%
V5BMT5	Trypanosoma cruzi	28%	100%

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