LeishMANIAdb
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Cytochrome c oxidase assembly factor 5

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Cytochrome c oxidase assembly factor 5
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4H3Y6_LEIBR
TriTrypDb:
LbrM.04.0720 , LBRM2903_040016600
Length:
148

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H3Y6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H3Y6

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 112 114 PF00675 0.637
CLV_NRD_NRD_1 139 141 PF00675 0.610
CLV_NRD_NRD_1 89 91 PF00675 0.648
CLV_PCSK_KEX2_1 139 141 PF00082 0.610
CLV_PCSK_SKI1_1 38 42 PF00082 0.459
CLV_PCSK_SKI1_1 70 74 PF00082 0.639
DEG_APCC_DBOX_1 55 63 PF00400 0.439
DEG_SCF_FBW7_1 14 20 PF00400 0.626
DOC_CKS1_1 14 19 PF01111 0.627
DOC_PP4_FxxP_1 130 133 PF00568 0.531
DOC_WW_Pin1_4 13 18 PF00397 0.721
LIG_BIR_II_1 1 5 PF00653 0.582
LIG_BIR_III_4 117 121 PF00653 0.610
LIG_FHA_1 14 20 PF00498 0.626
LIG_LIR_Apic_2 128 133 PF02991 0.531
LIG_Pex14_1 92 96 PF04695 0.493
LIG_Rb_pABgroove_1 47 55 PF01858 0.489
LIG_SH2_STAP1 96 100 PF00017 0.512
LIG_SH2_STAT5 136 139 PF00017 0.535
LIG_SUMO_SIM_anti_2 48 54 PF11976 0.501
MOD_GlcNHglycan 144 147 PF01048 0.685
MOD_GlcNHglycan 22 25 PF01048 0.606
MOD_GSK3_1 13 20 PF00069 0.600
MOD_N-GLC_1 27 32 PF02516 0.512
MOD_NEK2_1 76 81 PF00069 0.536
MOD_PIKK_1 43 49 PF00454 0.481
MOD_PKA_2 43 49 PF00069 0.481
MOD_PKA_2 76 82 PF00069 0.526
MOD_Plk_4 125 131 PF00069 0.544
MOD_Plk_4 70 76 PF00069 0.529
MOD_ProDKin_1 13 19 PF00069 0.716
MOD_SUMO_rev_2 95 100 PF00179 0.583
TRG_DiLeu_BaLyEn_6 101 106 PF01217 0.525
TRG_DiLeu_BaLyEn_6 55 60 PF01217 0.440
TRG_ER_diArg_1 138 140 PF00400 0.592
TRG_ER_diArg_1 56 59 PF00400 0.449

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PCX0 Leptomonas seymouri 78% 100%
A0A0S4IMT7 Bodo saltans 68% 100%
A0A1X0NLQ6 Trypanosomatidae 68% 100%
A0A3S5H5D5 Leishmania donovani 94% 100%
A4HS86 Leishmania infantum 95% 100%
C9ZY82 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 67% 100%
E9AK74 Leishmania mexicana (strain MHOM/GT/2001/U1103) 94% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS