Putative ADP-ribosylation factor

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ADP-ribosylation factor, putative

Species:

Leishmania braziliensis

UniProt:

A4H3W8_LEIBR

TriTrypDb:

LbrM.04.0530 , LBRM2903_040010300

Length:

190

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4H3W8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H3W8

Function

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	1
GO:0006886	intracellular protein transport	4	1
GO:0008104	protein localization	4	1
GO:0009987	cellular process	1	1
GO:0015031	protein transport	4	1
GO:0016192	vesicle-mediated transport	4	1
GO:0033036	macromolecule localization	2	1
GO:0045184	establishment of protein localization	3	1
GO:0046907	intracellular transport	3	1
GO:0051179	localization	1	1
GO:0051234	establishment of localization	2	1
GO:0051641	cellular localization	2	1
GO:0051649	establishment of localization in cell	3	1
GO:0070727	cellular macromolecule localization	3	1
GO:0071702	organic substance transport	4	1
GO:0071705	nitrogen compound transport	4	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003824	catalytic activity	1	12
GO:0003924	GTPase activity	7	12
GO:0005488	binding	1	12
GO:0005525	GTP binding	5	12
GO:0016462	pyrophosphatase activity	5	12
GO:0016787	hydrolase activity	2	12
GO:0016817	hydrolase activity, acting on acid anhydrides	3	12
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	12
GO:0017076	purine nucleotide binding	4	12
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	12
GO:0019001	guanyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032561	guanyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	138	142	PF00656	0.405
CLV_PCSK_KEX2_1	72	74	PF00082	0.423
CLV_PCSK_PC1ET2_1	72	74	PF00082	0.406
CLV_PCSK_SKI1_1	108	112	PF00082	0.372
CLV_PCSK_SKI1_1	59	63	PF00082	0.312
DEG_APCC_DBOX_1	103	111	PF00400	0.339
DEG_COP1_1	41	49	PF00400	0.334
DOC_MAPK_DCC_7	43	51	PF00069	0.389
DOC_MAPK_gen_1	14	23	PF00069	0.267
DOC_MAPK_MEF2A_6	16	25	PF00069	0.294
DOC_MAPK_MEF2A_6	43	51	PF00069	0.411
DOC_PP1_RVXF_1	57	64	PF00149	0.304
DOC_WW_Pin1_4	132	137	PF00397	0.320
LIG_14-3-3_CanoR_1	108	114	PF00244	0.424
LIG_14-3-3_CanoR_1	59	64	PF00244	0.425
LIG_BIR_III_4	26	30	PF00653	0.304
LIG_BRCT_BRCA1_1	5	9	PF00533	0.609
LIG_FHA_1	29	35	PF00498	0.297
LIG_FHA_1	60	66	PF00498	0.451
LIG_FHA_2	133	139	PF00498	0.339
LIG_FHA_2	30	36	PF00498	0.425
LIG_FHA_2	39	45	PF00498	0.425
LIG_LIR_Nem_3	173	179	PF02991	0.320
LIG_LIR_Nem_3	55	61	PF02991	0.304
LIG_LIR_Nem_3	6	12	PF02991	0.502
LIG_NRBOX	106	112	PF00104	0.320
LIG_PALB2_WD40_1	4	12	PF16756	0.523
LIG_PCNA_PIPBox_1	71	80	PF02747	0.320
LIG_PCNA_yPIPBox_3	71	79	PF02747	0.320
LIG_PDZ_Class_3	185	190	PF00595	0.561
LIG_Pex14_1	78	82	PF04695	0.304
LIG_Pex14_2	9	13	PF04695	0.264
LIG_PTB_Apo_2	57	64	PF02174	0.320
LIG_SH2_CRK	58	62	PF00017	0.304
LIG_SH2_STAT5	156	159	PF00017	0.391
LIG_SH2_STAT5	163	166	PF00017	0.327
LIG_TYR_ITIM	56	61	PF00017	0.304
LIG_UBA3_1	121	127	PF00899	0.349
LIG_UBA3_1	33	38	PF00899	0.376
MOD_CK1_1	42	48	PF00069	0.419
MOD_CK2_1	132	138	PF00069	0.339
MOD_CK2_1	29	35	PF00069	0.199
MOD_CK2_1	38	44	PF00069	0.164
MOD_GlcNHglycan	116	119	PF01048	0.338
MOD_GlcNHglycan	5	8	PF01048	0.454
MOD_GSK3_1	38	45	PF00069	0.342
MOD_N-GLC_1	59	64	PF02516	0.429
MOD_NMyristoyl	1	7	PF02799	0.498
MOD_PK_1	16	22	PF00069	0.412
MOD_PKA_1	16	22	PF00069	0.315
MOD_PKA_2	42	48	PF00069	0.425
MOD_Plk_1	59	65	PF00069	0.451
MOD_Plk_4	16	22	PF00069	0.313
MOD_Plk_4	29	35	PF00069	0.279
MOD_ProDKin_1	132	138	PF00069	0.320
TRG_DiLeu_BaEn_1	106	111	PF01217	0.320
TRG_DiLeu_BaLyEn_6	111	116	PF01217	0.361
TRG_ENDOCYTIC_2	176	179	PF00928	0.425
TRG_ENDOCYTIC_2	58	61	PF00928	0.304
TRG_ER_diArg_1	97	100	PF00400	0.394
TRG_Pf-PMV_PEXEL_1	108	113	PF00026	0.308
TRG_Pf-PMV_PEXEL_1	146	150	PF00026	0.451

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3A0	Leptomonas seymouri	31%	70%
A0A0N0P3Q3	Leptomonas seymouri	83%	100%
A0A0N0P4P7	Leptomonas seymouri	35%	100%
A0A0N0P633	Leptomonas seymouri	49%	100%
A0A0N0P8D4	Leptomonas seymouri	39%	100%
A0A0N0P8Z3	Leptomonas seymouri	37%	100%
A0A0N1HS40	Leptomonas seymouri	39%	100%
A0A0N1HTN6	Leptomonas seymouri	41%	100%
A0A0N1I3A9	Leptomonas seymouri	33%	100%
A0A0N1I556	Leptomonas seymouri	50%	100%
A0A0N1I6N0	Leptomonas seymouri	40%	100%
A0A0N1PBC8	Leptomonas seymouri	30%	70%
A0A0N1PD39	Leptomonas seymouri	34%	100%
A0A0S4IQT8	Bodo saltans	35%	100%
A0A0S4IS60	Bodo saltans	46%	100%
A0A0S4J2X3	Bodo saltans	40%	100%
A0A0S4J3L7	Bodo saltans	34%	100%
A0A0S4J5U8	Bodo saltans	40%	100%
A0A0S4J8H6	Bodo saltans	64%	100%
A0A0S4JHS1	Bodo saltans	31%	83%
A0A0S4JK65	Bodo saltans	40%	100%
A0A0S4JQ13	Bodo saltans	36%	97%
A0A0S4JWF1	Bodo saltans	29%	67%
A0A0S4KGN8	Bodo saltans	29%	85%
A0A0S4KJ70	Bodo saltans	51%	89%
A0A0S4KKS9	Bodo saltans	52%	100%
A0A1X0NKM5	Trypanosomatidae	42%	100%
A0A1X0NKZ8	Trypanosomatidae	38%	98%
A0A1X0NLB1	Trypanosomatidae	71%	100%
A0A1X0NLP5	Trypanosomatidae	35%	100%
A0A1X0NR74	Trypanosomatidae	27%	91%
A0A1X0NT19	Trypanosomatidae	39%	100%
A0A1X0NZX3	Trypanosomatidae	39%	100%
A0A1X0P0A2	Trypanosomatidae	34%	100%
A0A1X0P0D4	Trypanosomatidae	34%	98%
A0A1X0P1V3	Trypanosomatidae	27%	82%
A0A1X0P1Y5	Trypanosomatidae	30%	100%
A0A1X0P2L5	Trypanosomatidae	33%	98%
A0A1X0P5P0	Trypanosomatidae	49%	100%
A0A1X0P676	Trypanosomatidae	35%	99%
A0A1X0P850	Trypanosomatidae	29%	69%
A0A221LG87	Leishmania donovani	33%	97%
A0A3Q8IDS2	Leishmania donovani	33%	100%
A0A3Q8IFX9	Leishmania donovani	33%	100%
A0A3R7KSW8	Trypanosoma rangeli	35%	100%
A0A3R7L2X6	Trypanosoma rangeli	50%	100%
A0A3R7MW79	Trypanosoma rangeli	70%	100%
A0A3R7NC73	Trypanosoma rangeli	40%	100%
A0A3R7NMH3	Trypanosoma rangeli	35%	100%
A0A3R7RGT1	Trypanosoma rangeli	36%	100%
A0A3S5H598	Leishmania donovani	36%	100%
A0A3S5H5A9	Leishmania donovani	94%	100%
A0A3S5IQP0	Trypanosoma rangeli	41%	100%
A0A3S5ISB1	Trypanosoma rangeli	35%	100%
A0A3S7WU76	Leishmania donovani	39%	100%
A0A3S7X4X3	Leishmania donovani	49%	100%
A0A3S7X8N3	Leishmania donovani	40%	100%
A0A3S7XC57	Leishmania donovani	35%	100%
A0A422MYB1	Trypanosoma rangeli	49%	100%
A0A422MYF8	Trypanosoma rangeli	55%	100%
A0A422MZM4	Trypanosoma rangeli	33%	98%
A0A422NNC6	Trypanosoma rangeli	36%	99%
A0A422NRN0	Trypanosoma rangeli	37%	100%
A0A422NW53	Trypanosoma rangeli	33%	100%
A1CRG9	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	33%	100%
A1D4D1	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	33%	100%
A3LTA2	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	32%	100%
A4H3V3	Leishmania braziliensis	39%	95%
A4H449	Leishmania braziliensis	34%	100%
A4H8R6	Leishmania braziliensis	33%	100%
A4H8V3	Leishmania braziliensis	40%	100%
A4HH98	Leishmania braziliensis	38%	100%
A4HJL1	Leishmania braziliensis	50%	97%
A4HJR7	Leishmania braziliensis	48%	96%
A4HLP5	Leishmania braziliensis	29%	87%
A4HM52	Leishmania braziliensis	40%	100%
A4HNU2	Leishmania braziliensis	30%	66%
A4HQE3	Leishmania braziliensis	34%	100%
A4HS29	Leishmania infantum	36%	100%
A4HS43	Leishmania infantum	94%	100%
A4HSC6	Leishmania infantum	33%	97%
A4HX34	Leishmania infantum	33%	100%
A4HX72	Leishmania infantum	39%	100%
A4I4E4	Leishmania infantum	38%	100%
A4I5R5	Leishmania infantum	33%	100%
A4I784	Leishmania infantum	49%	100%
A4IAR4	Leishmania infantum	40%	100%
A4IE34	Leishmania infantum	35%	100%
A5DR82	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	31%	100%
A5E5G3	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	30%	100%
A6NH57	Homo sapiens	34%	100%
A8ISN6	Chlamydomonas reinhardtii	37%	100%
B5FYQ0	Taeniopygia guttata	35%	100%
C9ZL19	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
C9ZPY6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	98%
C9ZR33	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	100%
C9ZTU8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZVV9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	100%
C9ZY21	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	98%
C9ZY41	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	72%	100%
C9ZZD4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	100%
C9ZZD6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	100%
D0A1F6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	71%
D0A2E8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
D0A2Q7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	70%
D0A3V1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	69%
E9ADU4	Leishmania major	38%	100%
E9AEJ0	Leishmania major	39%	100%
E9AHL7	Leishmania infantum	50%	100%
E9AIU0	Leishmania braziliensis	33%	100%
E9AK16	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
E9AK30	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
E9AKA7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	97%
E9ALY6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	37%	100%
E9AQU9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E9ARC9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	39%	100%
E9AU58	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
E9B110	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E9B229	Leishmania mexicana (strain MHOM/GT/2001/U1103)	50%	100%
E9B278	Leishmania mexicana (strain MHOM/GT/2001/U1103)	49%	100%
E9B5Q1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	37%	100%
F1PTE3	Canis lupus familiaris	25%	94%
F4IZ82	Arabidopsis thaliana	34%	100%
O00909	Dictyostelium discoideum	51%	100%
O04266	Brassica campestris	34%	98%
O04267	Brassica campestris	36%	97%
O04834	Arabidopsis thaliana	36%	98%
O08697	Rattus norvegicus	39%	100%
O23778	Catharanthus roseus	49%	100%
O42819	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	29%	88%
O45379	Caenorhabditis elegans	35%	100%
O48649	Salix bakko	53%	100%
O48920	Vigna unguiculata	51%	100%
O88848	Mus musculus	36%	100%
O95716	Homo sapiens	30%	87%
P01123	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	27%	92%
P07560	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	29%	88%
P0C583	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	33%	100%
P0C950	Aspergillus niger	30%	100%
P0C951	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	32%	100%
P0CM16	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	52%	100%
P0CM17	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	52%	100%
P0CR30	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	33%	100%
P0CR31	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	33%	100%
P0CT16	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	33%	100%
P0CT17	Magnaporthe oryzae (strain Y34)	33%	100%
P0DH91	Arabidopsis thaliana	51%	100%
P10536	Rattus norvegicus	29%	95%
P11076	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	48%	100%
P11620	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	27%	94%
P18085	Homo sapiens	52%	100%
P19146	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	48%	100%
P20606	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	32%	100%
P20790	Dictyostelium discoideum	24%	91%
P20791	Dictyostelium discoideum	25%	94%
P22125	Diplobatis ommata	28%	94%
P22274	Candida albicans (strain SC5314 / ATCC MYA-2876)	49%	100%
P25160	Drosophila melanogaster	41%	100%
P26990	Gallus gallus	50%	100%
P26991	Giardia intestinalis	48%	99%
P28186	Arabidopsis thaliana	25%	88%
P33723	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	27%	94%
P34140	Dictyostelium discoideum	28%	92%
P34212	Caenorhabditis elegans	43%	100%
P34727	Ajellomyces capsulatus	51%	100%
P36397	Arabidopsis thaliana	51%	100%
P36404	Homo sapiens	39%	100%
P36405	Homo sapiens	35%	100%
P36536	Mus musculus	32%	96%
P36579	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	50%	100%
P36861	Volvox carteri	30%	88%
P37996	Rattus norvegicus	36%	100%
P38116	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	42%	100%
P40616	Homo sapiens	42%	100%
P40617	Homo sapiens	41%	95%
P40940	Arabidopsis thaliana	41%	100%
P40945	Drosophila melanogaster	51%	100%
P40946	Drosophila melanogaster	49%	100%
P40994	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	45%	100%
P49076	Zea mays	52%	100%
P49702	Gallus gallus	50%	100%
P49703	Homo sapiens	39%	95%
P51146	Rattus norvegicus	30%	89%
P51153	Homo sapiens	26%	94%
P51643	Xenopus laevis	52%	100%
P51644	Xenopus laevis	50%	100%
P51645	Xenopus laevis	50%	100%
P51646	Rattus norvegicus	42%	100%
P51821	Chlamydomonas reinhardtii	51%	100%
P51822	Daucus carota	51%	100%
P51823	Oryza sativa subsp. japonica	51%	100%
P51824	Solanum tuberosum	51%	96%
P52884	Solanum lycopersicum	35%	98%
P56559	Homo sapiens	41%	99%
P61017	Canis lupus familiaris	30%	89%
P61018	Homo sapiens	30%	89%
P61204	Homo sapiens	51%	100%
P61205	Mus musculus	51%	100%
P61206	Rattus norvegicus	51%	100%
P61207	Takifugu rubripes	51%	100%
P61208	Mus musculus	41%	99%
P61209	Drosophila melanogaster	52%	100%
P61210	Locusta migratoria	52%	100%
P61211	Mus musculus	42%	100%
P61212	Rattus norvegicus	42%	100%
P61213	Mus musculus	41%	95%
P61214	Rattus norvegicus	41%	95%
P61750	Mus musculus	50%	100%
P61751	Rattus norvegicus	50%	100%
P62330	Homo sapiens	49%	100%
P62331	Mus musculus	49%	100%
P62332	Rattus norvegicus	49%	100%
P62820	Homo sapiens	28%	93%
P62821	Mus musculus	28%	93%
P62822	Canis lupus familiaris	28%	93%
P78976	Hypocrea jecorina	32%	100%
P84077	Homo sapiens	53%	100%
P84078	Mus musculus	53%	100%
P84079	Rattus norvegicus	53%	100%
P84080	Bos taurus	53%	100%
P84081	Bos taurus	52%	100%
P84082	Rattus norvegicus	52%	100%
P84083	Rattus norvegicus	51%	100%
P84084	Mus musculus	51%	100%
P84085	Homo sapiens	51%	100%
P90726	Caenorhabditis briggsae	29%	94%
P91924	Dugesia japonica	52%	100%
Q007T5	Sus scrofa	49%	100%
Q01474	Arabidopsis thaliana	33%	98%
Q01475	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	33%	100%
Q01890	Phytophthora infestans	28%	95%
Q02804	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	32%	96%
Q05974	Lymnaea stagnalis	28%	93%
Q06396	Oryza sativa subsp. japonica	51%	100%
Q06849	Drosophila melanogaster	39%	100%
Q06AU4	Sus scrofa	32%	73%
Q06AU7	Sus scrofa	28%	95%
Q08DE8	Bos taurus	27%	95%
Q09767	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	35%	100%
Q0CUN7	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	32%	100%
Q0IIM2	Bos taurus	37%	100%
Q0P5N6	Homo sapiens	28%	96%
Q0UKC0	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	31%	100%
Q0VC18	Bos taurus	38%	95%
Q10943	Caenorhabditis elegans	53%	100%
Q13795	Homo sapiens	33%	95%
Q18510	Caenorhabditis elegans	35%	100%
Q19705	Caenorhabditis elegans	38%	100%
Q1MTE5	Danio rerio	35%	100%
Q20758	Caenorhabditis elegans	43%	100%
Q23445	Caenorhabditis elegans	34%	98%
Q25761	Plasmodium falciparum (isolate NF54)	47%	100%
Q2HA55	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	34%	100%
Q2HJH2	Bos taurus	28%	95%
Q2KI07	Bos taurus	34%	100%
Q2KJ96	Bos taurus	42%	100%
Q2TA37	Bos taurus	39%	100%
Q2TBW6	Bos taurus	35%	100%
Q2YDM1	Bos taurus	42%	100%
Q32LJ2	Bos taurus	32%	95%
Q39222	Arabidopsis thaliana	31%	88%
Q39434	Beta vulgaris	31%	89%
Q39572	Chlamydomonas reinhardtii	29%	88%
Q3SXC5	Mus musculus	37%	99%
Q3SZF2	Bos taurus	50%	100%
Q3T0D7	Bos taurus	32%	96%
Q3T0M9	Bos taurus	41%	95%
Q3T0T7	Bos taurus	33%	96%
Q40191	Lotus japonicus	30%	84%
Q40193	Lotus japonicus	30%	88%
Q40194	Lotus japonicus	30%	87%
Q40520	Nicotiana tabacum	30%	86%
Q40522	Nicotiana tabacum	29%	86%
Q40523	Nicotiana tabacum	29%	88%
Q40723	Oryza sativa subsp. japonica	30%	88%
Q4P0I7	Ustilago maydis (strain 521 / FGSC 9021)	33%	100%
Q4Q0D7	Leishmania major	35%	100%
Q4Q404	Leishmania major	30%	88%
Q4Q5Y0	Leishmania major	49%	96%
Q4Q756	Leishmania major	33%	98%
Q4QEJ1	Leishmania major	40%	100%
Q4QEM9	Leishmania major	33%	100%
Q4QGD2	Leishmania major	28%	90%
Q4R4S4	Macaca fascicularis	37%	100%
Q4R5P2	Macaca fascicularis	53%	100%
Q4R8X3	Macaca fascicularis	29%	95%
Q4UB16	Theileria annulata	29%	86%
Q4WJS7	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	32%	100%
Q52NJ2	Sus scrofa	28%	93%
Q52NJ3	Sus scrofa	32%	96%
Q52NJ4	Sus scrofa	35%	100%
Q54HK2	Dictyostelium discoideum	43%	100%
Q54I24	Dictyostelium discoideum	40%	88%
Q54JJ3	Dictyostelium discoideum	46%	100%
Q54R04	Dictyostelium discoideum	36%	100%
Q54RX9	Dictyostelium discoideum	30%	89%
Q54UF1	Dictyostelium discoideum	40%	100%
Q54V41	Dictyostelium discoideum	46%	100%
Q54V47	Dictyostelium discoideum	46%	100%
Q54Y14	Dictyostelium discoideum	41%	98%
Q54YV7	Dictyostelium discoideum	26%	97%
Q550H6	Dictyostelium discoideum	32%	85%
Q559R0	Dictyostelium discoideum	40%	100%
Q55AD9	Dictyostelium discoideum	41%	100%
Q58DI9	Bos taurus	44%	100%
Q58DS5	Bos taurus	26%	94%
Q59S78	Candida albicans (strain SC5314 / ATCC MYA-2876)	31%	100%
Q5BGB9	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	33%	100%
Q5BK71	Rattus norvegicus	43%	100%
Q5E9I6	Bos taurus	51%	100%
Q5EA19	Bos taurus	29%	94%
Q5HZY2	Rattus norvegicus	33%	96%
Q5M9P8	Danio rerio	35%	100%
Q5PYH3	Sus scrofa	33%	96%
Q5R4A3	Pongo abelii	25%	92%
Q5R4G5	Pongo abelii	36%	100%
Q5R548	Pongo abelii	32%	96%
Q5R579	Pongo abelii	33%	95%
Q5R5P7	Pongo abelii	51%	100%
Q5R6E7	Pongo abelii	34%	100%
Q5RCF1	Pongo abelii	52%	100%
Q5RCQ6	Pongo abelii	28%	100%
Q5RE13	Pongo abelii	28%	95%
Q5REU3	Pongo abelii	39%	95%
Q5RFN0	Pongo abelii	29%	93%
Q5U1Y1	Rattus norvegicus	31%	73%
Q5VLR7	Leishmania donovani	50%	100%
Q5ZKQ8	Gallus gallus	33%	100%
Q60Z38	Caenorhabditis briggsae	37%	100%
Q61LA8	Caenorhabditis briggsae	53%	100%
Q627K4	Caenorhabditis briggsae	38%	100%
Q63055	Rattus norvegicus	33%	95%
Q64008	Mus musculus	31%	73%
Q66HA6	Rattus norvegicus	34%	100%
Q68EK7	Danio rerio	29%	89%
Q6BVA7	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	30%	100%
Q6CB54	Yarrowia lipolytica (strain CLIB 122 / E 150)	36%	100%
Q6CWR7	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	30%	100%
Q6FUZ9	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	32%	100%
Q6IMM3	Leishmania major	50%	97%
Q6NYB7	Rattus norvegicus	28%	93%
Q6NZW8	Danio rerio	35%	100%
Q6P068	Mus musculus	39%	100%
Q6P3A9	Mus musculus	44%	100%
Q6P8C8	Xenopus tropicalis	32%	100%
Q755D7	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	31%	100%
Q75A26	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	47%	100%
Q76NM7	Plasmodium falciparum (isolate 3D7)	32%	92%
Q7KQL3	Plasmodium falciparum (isolate 3D7)	47%	100%
Q7RVM2	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	52%	100%
Q7T3A4	Danio rerio	25%	95%
Q80ZU0	Mus musculus	42%	100%
Q877B9	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	33%	100%
Q8BGR6	Mus musculus	29%	93%
Q8BSL7	Mus musculus	52%	100%
Q8BXL7	Mus musculus	33%	95%
Q8MQT8	Giardia intestinalis	32%	99%
Q8MXS1	Caenorhabditis elegans	29%	94%
Q8N4G2	Homo sapiens	38%	99%
Q8N8L6	Homo sapiens	34%	78%
Q8QHI3	Xenopus laevis	35%	100%
Q8SQH8	Encephalitozoon cuniculi (strain GB-M1)	38%	92%
Q8SS09	Encephalitozoon cuniculi (strain GB-M1)	33%	86%
Q8VEA8	Mus musculus	28%	95%
Q8VEH3	Mus musculus	33%	100%
Q8VY57	Arabidopsis thaliana	33%	100%
Q8W4C8	Arabidopsis thaliana	38%	100%
Q8WQ53	Geodia cydonium	28%	83%
Q91ZR1	Mus musculus	30%	89%
Q93Y31	Arabidopsis thaliana	32%	100%
Q94231	Caenorhabditis elegans	45%	100%
Q94650	Plasmodium falciparum	47%	100%
Q96283	Arabidopsis thaliana	29%	88%
Q96361	Brassica rapa subsp. pekinensis	41%	100%
Q969Q4	Homo sapiens	44%	97%
Q96BM9	Homo sapiens	33%	100%
Q96KC2	Homo sapiens	41%	100%
Q99PE9	Mus musculus	40%	95%
Q9BZG1	Homo sapiens	30%	73%
Q9CQC9	Mus musculus	33%	96%
Q9CQW2	Mus musculus	34%	100%
Q9D0J4	Mus musculus	39%	100%
Q9D1G1	Mus musculus	29%	95%
Q9D4P0	Mus musculus	41%	100%
Q9DD03	Mus musculus	25%	94%
Q9FIF9	Arabidopsis thaliana	30%	88%
Q9FJN8	Arabidopsis thaliana	30%	84%
Q9GP33	Echinococcus multilocularis	31%	85%
Q9H0F7	Homo sapiens	36%	100%
Q9H0U4	Homo sapiens	28%	95%
Q9LNW1	Arabidopsis thaliana	31%	89%
Q9LQC8	Arabidopsis thaliana	51%	100%
Q9N6B0	Leishmania donovani	38%	100%
Q9NR31	Homo sapiens	32%	96%
Q9NVJ2	Homo sapiens	34%	100%
Q9NXU5	Homo sapiens	29%	93%
Q9P4C8	Komagataella phaffii (strain GS115 / ATCC 20864)	31%	100%
Q9QVY3	Cricetulus griseus	33%	96%
Q9QXJ4	Mus musculus	32%	78%
Q9SHU5	Arabidopsis thaliana	45%	93%
Q9SMQ6	Arabidopsis thaliana	28%	85%
Q9TVU5	Theileria parva	29%	86%
Q9U0T6	Leishmania major	93%	100%
Q9VHV5	Drosophila melanogaster	33%	100%
Q9WUL7	Mus musculus	35%	100%
Q9XZX2	Leishmania major	37%	95%
Q9Y689	Homo sapiens	42%	100%
Q9Y6B6	Homo sapiens	33%	96%
Q9Y7Z2	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	50%	100%
Q9ZPX1	Arabidopsis thaliana	38%	100%
V5B891	Trypanosoma cruzi	39%	100%
V5DJR8	Trypanosoma cruzi	43%	100%