RNA helicase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

RNA helicase

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H3V5_LEIBR

TriTrypDb:

LbrM.04.0390 , LBRM2903_040008600

Length:

291

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A4H3V5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H3V5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	131	135	PF00656	0.531
CLV_NRD_NRD_1	124	126	PF00675	0.525
CLV_NRD_NRD_1	195	197	PF00675	0.474
CLV_NRD_NRD_1	210	212	PF00675	0.433
CLV_NRD_NRD_1	259	261	PF00675	0.514
CLV_NRD_NRD_1	281	283	PF00675	0.542
CLV_PCSK_FUR_1	256	260	PF00082	0.506
CLV_PCSK_KEX2_1	115	117	PF00082	0.479
CLV_PCSK_KEX2_1	195	197	PF00082	0.474
CLV_PCSK_KEX2_1	209	211	PF00082	0.432
CLV_PCSK_KEX2_1	258	260	PF00082	0.516
CLV_PCSK_KEX2_1	281	283	PF00082	0.542
CLV_PCSK_PC1ET2_1	115	117	PF00082	0.479
CLV_PCSK_PC1ET2_1	209	211	PF00082	0.506
CLV_PCSK_PC1ET2_1	281	283	PF00082	0.542
CLV_PCSK_SKI1_1	115	119	PF00082	0.494
CLV_PCSK_SKI1_1	126	130	PF00082	0.490
CLV_PCSK_SKI1_1	173	177	PF00082	0.465
CLV_PCSK_SKI1_1	190	194	PF00082	0.406
CLV_PCSK_SKI1_1	195	199	PF00082	0.439
CLV_PCSK_SKI1_1	27	31	PF00082	0.489
CLV_PCSK_SKI1_1	273	277	PF00082	0.545
DEG_APCC_DBOX_1	10	18	PF00400	0.474
DEG_Nend_UBRbox_4	1	3	PF02207	0.531
DOC_CYCLIN_yCln2_LP_2	96	102	PF00134	0.763
DOC_MAPK_DCC_7	51	61	PF00069	0.487
DOC_MAPK_FxFP_2	55	58	PF00069	0.490
DOC_MAPK_gen_1	115	124	PF00069	0.496
DOC_PP2B_LxvP_1	96	99	PF13499	0.571
DOC_PP4_FxxP_1	55	58	PF00568	0.525
DOC_PP4_FxxP_1	84	87	PF00568	0.552
DOC_USP7_MATH_1	18	22	PF00917	0.519
DOC_USP7_MATH_1	262	266	PF00917	0.560
DOC_USP7_MATH_1	42	46	PF00917	0.525
DOC_USP7_MATH_1	88	92	PF00917	0.565
DOC_USP7_UBL2_3	111	115	PF12436	0.504
DOC_WW_Pin1_4	227	232	PF00397	0.735
DOC_WW_Pin1_4	86	91	PF00397	0.754
LIG_14-3-3_CanoR_1	173	179	PF00244	0.465
LIG_14-3-3_CanoR_1	27	32	PF00244	0.492
LIG_BRCT_BRCA1_1	167	171	PF00533	0.497
LIG_FHA_1	184	190	PF00498	0.504
LIG_FHA_2	118	124	PF00498	0.504
LIG_FHA_2	196	202	PF00498	0.592
LIG_GSK3_LRP6_1	86	92	PF00069	0.558
LIG_LIR_Apic_2	52	58	PF02991	0.482
LIG_LIR_Gen_1	52	61	PF02991	0.515
LIG_LIR_Nem_3	52	56	PF02991	0.504
LIG_MYND_1	94	98	PF01753	0.560
LIG_PCNA_yPIPBox_3	35	44	PF02747	0.515
LIG_Pex14_2	275	279	PF04695	0.551
LIG_Pex14_2	53	57	PF04695	0.502
LIG_REV1ctd_RIR_1	273	282	PF16727	0.547
LIG_SH2_STAP1	141	145	PF00017	0.492
LIG_SH3_3	74	80	PF00018	0.609
LIG_SH3_3	84	90	PF00018	0.631
LIG_SH3_3	91	97	PF00018	0.651
LIG_SUMO_SIM_par_1	41	49	PF11976	0.599
LIG_SUMO_SIM_par_1	57	63	PF11976	0.501
LIG_WRC_WIRS_1	184	189	PF05994	0.508
MOD_CDK_SPK_2	227	232	PF00069	0.567
MOD_CK1_1	71	77	PF00069	0.658
MOD_CK1_1	89	95	PF00069	0.682
MOD_CK2_1	117	123	PF00069	0.498
MOD_CK2_1	195	201	PF00069	0.551
MOD_GlcNHglycan	136	139	PF01048	0.473
MOD_GlcNHglycan	20	23	PF01048	0.496
MOD_GlcNHglycan	264	267	PF01048	0.607
MOD_GSK3_1	126	133	PF00069	0.546
MOD_GSK3_1	65	72	PF00069	0.565
MOD_GSK3_1	86	93	PF00069	0.687
MOD_N-GLC_1	249	254	PF02516	0.479
MOD_NEK2_1	139	144	PF00069	0.502
MOD_NEK2_1	154	159	PF00069	0.426
MOD_NEK2_1	249	254	PF00069	0.479
MOD_NEK2_1	60	65	PF00069	0.539
MOD_NEK2_2	174	179	PF00069	0.466
MOD_PIKK_1	249	255	PF00454	0.481
MOD_PKA_1	195	201	PF00069	0.467
MOD_PKA_2	195	201	PF00069	0.572
MOD_Plk_4	271	277	PF00069	0.511
MOD_Plk_4	60	66	PF00069	0.590
MOD_ProDKin_1	227	233	PF00069	0.738
MOD_ProDKin_1	86	92	PF00069	0.757
TRG_DiLeu_BaLyEn_6	55	60	PF01217	0.492
TRG_ER_diArg_1	194	196	PF00400	0.476
TRG_ER_diArg_1	256	259	PF00400	0.505
TRG_NLS_MonoCore_2	279	284	PF00514	0.545
TRG_NLS_MonoExtC_3	279	285	PF00514	0.544
TRG_NLS_MonoExtN_4	278	284	PF00514	0.546

Homologs


Protein	Taxonomy	Sequence identity	Coverage
Q9XZX5	Leishmania major	89%	100%