LeishMANIAdb
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Putative adenosine monophosphate deaminase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative adenosine monophosphate deaminase
Gene product:
adenosine monophosphate deaminase, putative
Species:
Leishmania braziliensis
UniProt:
A4H3U8_LEIBR
TriTrypDb:
LbrM.04.0320 , LBRM2903_040007800 *
Length:
1942

Annotations

LeishMANIAdb annotations

A conserved enzyme, likely cytosolic without any TM segments.

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 5
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 13
NetGPI no yes: 0, no: 13
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 1
GO:0005829 cytosol 2 3
GO:0005930 axoneme 2 1
GO:0110165 cellular anatomical entity 1 3

Expansion

Sequence features

A4H3U8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 14
GO:0006163 purine nucleotide metabolic process 5 14
GO:0006164 purine nucleotide biosynthetic process 6 14
GO:0006188 IMP biosynthetic process 8 14
GO:0006725 cellular aromatic compound metabolic process 3 14
GO:0006753 nucleoside phosphate metabolic process 4 14
GO:0006793 phosphorus metabolic process 3 14
GO:0006796 phosphate-containing compound metabolic process 4 14
GO:0006807 nitrogen compound metabolic process 2 14
GO:0008152 metabolic process 1 14
GO:0009058 biosynthetic process 2 14
GO:0009117 nucleotide metabolic process 5 14
GO:0009123 nucleoside monophosphate metabolic process 5 14
GO:0009124 nucleoside monophosphate biosynthetic process 6 14
GO:0009126 purine nucleoside monophosphate metabolic process 6 14
GO:0009127 purine nucleoside monophosphate biosynthetic process 7 14
GO:0009150 purine ribonucleotide metabolic process 6 14
GO:0009152 purine ribonucleotide biosynthetic process 7 14
GO:0009156 ribonucleoside monophosphate biosynthetic process 7 14
GO:0009161 ribonucleoside monophosphate metabolic process 6 14
GO:0009165 nucleotide biosynthetic process 6 14
GO:0009167 purine ribonucleoside monophosphate metabolic process 7 14
GO:0009168 purine ribonucleoside monophosphate biosynthetic process 8 14
GO:0009259 ribonucleotide metabolic process 5 14
GO:0009260 ribonucleotide biosynthetic process 6 14
GO:0009987 cellular process 1 14
GO:0018130 heterocycle biosynthetic process 4 14
GO:0019438 aromatic compound biosynthetic process 4 14
GO:0019637 organophosphate metabolic process 3 14
GO:0019693 ribose phosphate metabolic process 4 14
GO:0032261 purine nucleotide salvage 5 14
GO:0032264 IMP salvage 7 14
GO:0034641 cellular nitrogen compound metabolic process 3 14
GO:0034654 nucleobase-containing compound biosynthetic process 4 14
GO:0043094 cellular metabolic compound salvage 3 14
GO:0043101 purine-containing compound salvage 4 14
GO:0043173 nucleotide salvage 4 14
GO:0044237 cellular metabolic process 2 14
GO:0044238 primary metabolic process 2 14
GO:0044249 cellular biosynthetic process 3 14
GO:0044271 cellular nitrogen compound biosynthetic process 4 14
GO:0044281 small molecule metabolic process 2 14
GO:0046040 IMP metabolic process 7 14
GO:0046390 ribose phosphate biosynthetic process 5 14
GO:0046483 heterocycle metabolic process 3 14
GO:0055086 nucleobase-containing small molecule metabolic process 3 14
GO:0071704 organic substance metabolic process 2 14
GO:0072521 purine-containing compound metabolic process 4 14
GO:0072522 purine-containing compound biosynthetic process 5 14
GO:0090407 organophosphate biosynthetic process 4 14
GO:0106380 purine ribonucleotide salvage 6 14
GO:1901135 carbohydrate derivative metabolic process 3 14
GO:1901137 carbohydrate derivative biosynthetic process 4 14
GO:1901293 nucleoside phosphate biosynthetic process 5 14
GO:1901360 organic cyclic compound metabolic process 3 14
GO:1901362 organic cyclic compound biosynthetic process 4 14
GO:1901564 organonitrogen compound metabolic process 3 14
GO:1901566 organonitrogen compound biosynthetic process 4 14
GO:1901576 organic substance biosynthetic process 3 14
GO:0046033 AMP metabolic process 7 3
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 14
GO:0003876 AMP deaminase activity 5 14
GO:0016787 hydrolase activity 2 14
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 3 14
GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 4 14
GO:0019239 deaminase activity 3 14
GO:0047623 adenosine-phosphate deaminase activity 4 14

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1220 1224 PF00656 0.359
CLV_C14_Caspase3-7 1290 1294 PF00656 0.292
CLV_NRD_NRD_1 1168 1170 PF00675 0.432
CLV_NRD_NRD_1 1182 1184 PF00675 0.304
CLV_NRD_NRD_1 1440 1442 PF00675 0.398
CLV_NRD_NRD_1 1485 1487 PF00675 0.359
CLV_NRD_NRD_1 1563 1565 PF00675 0.303
CLV_NRD_NRD_1 1783 1785 PF00675 0.669
CLV_NRD_NRD_1 1876 1878 PF00675 0.624
CLV_NRD_NRD_1 1889 1891 PF00675 0.770
CLV_NRD_NRD_1 332 334 PF00675 0.353
CLV_NRD_NRD_1 669 671 PF00675 0.526
CLV_NRD_NRD_1 701 703 PF00675 0.546
CLV_NRD_NRD_1 734 736 PF00675 0.414
CLV_NRD_NRD_1 917 919 PF00675 0.329
CLV_NRD_NRD_1 954 956 PF00675 0.596
CLV_PCSK_FUR_1 1482 1486 PF00082 0.359
CLV_PCSK_FUR_1 330 334 PF00082 0.314
CLV_PCSK_FUR_1 732 736 PF00082 0.359
CLV_PCSK_KEX2_1 1168 1170 PF00082 0.439
CLV_PCSK_KEX2_1 1182 1184 PF00082 0.355
CLV_PCSK_KEX2_1 1332 1334 PF00082 0.359
CLV_PCSK_KEX2_1 1440 1442 PF00082 0.398
CLV_PCSK_KEX2_1 1484 1486 PF00082 0.359
CLV_PCSK_KEX2_1 1563 1565 PF00082 0.310
CLV_PCSK_KEX2_1 1783 1785 PF00082 0.671
CLV_PCSK_KEX2_1 1889 1891 PF00082 0.555
CLV_PCSK_KEX2_1 332 334 PF00082 0.352
CLV_PCSK_KEX2_1 671 673 PF00082 0.493
CLV_PCSK_KEX2_1 700 702 PF00082 0.550
CLV_PCSK_KEX2_1 732 734 PF00082 0.418
CLV_PCSK_KEX2_1 954 956 PF00082 0.624
CLV_PCSK_PC1ET2_1 1332 1334 PF00082 0.359
CLV_PCSK_PC1ET2_1 671 673 PF00082 0.453
CLV_PCSK_SKI1_1 1013 1017 PF00082 0.493
CLV_PCSK_SKI1_1 1235 1239 PF00082 0.429
CLV_PCSK_SKI1_1 1265 1269 PF00082 0.359
CLV_PCSK_SKI1_1 1673 1677 PF00082 0.468
CLV_PCSK_SKI1_1 1763 1767 PF00082 0.661
CLV_PCSK_SKI1_1 1889 1893 PF00082 0.565
CLV_PCSK_SKI1_1 458 462 PF00082 0.344
CLV_PCSK_SKI1_1 569 573 PF00082 0.577
CLV_PCSK_SKI1_1 918 922 PF00082 0.378
CLV_Separin_Metazoa 1834 1838 PF03568 0.491
DEG_APCC_DBOX_1 1234 1242 PF00400 0.359
DEG_APCC_DBOX_1 1264 1272 PF00400 0.359
DEG_SCF_FBW7_1 975 981 PF00400 0.488
DEG_SCF_FBW7_2 1725 1732 PF00400 0.474
DEG_SCF_FBW7_2 703 710 PF00400 0.458
DEG_SPOP_SBC_1 1821 1825 PF00917 0.582
DEG_SPOP_SBC_1 1924 1928 PF00917 0.605
DEG_SPOP_SBC_1 752 756 PF00917 0.355
DEG_SPOP_SBC_1 94 98 PF00917 0.479
DOC_AGCK_PIF_1 1487 1492 PF00069 0.331
DOC_CKS1_1 1816 1821 PF01111 0.639
DOC_CKS1_1 1850 1855 PF01111 0.539
DOC_CKS1_1 239 244 PF01111 0.610
DOC_CKS1_1 975 980 PF01111 0.497
DOC_CYCLIN_RxL_1 1177 1188 PF00134 0.359
DOC_CYCLIN_RxL_1 1259 1270 PF00134 0.359
DOC_CYCLIN_RxL_1 1886 1896 PF00134 0.584
DOC_CYCLIN_RxL_1 915 924 PF00134 0.327
DOC_CYCLIN_yCln2_LP_2 415 421 PF00134 0.257
DOC_MAPK_DCC_7 1621 1630 PF00069 0.274
DOC_MAPK_DCC_7 1641 1649 PF00069 0.234
DOC_MAPK_gen_1 1131 1140 PF00069 0.398
DOC_MAPK_gen_1 1168 1176 PF00069 0.268
DOC_MAPK_gen_1 1440 1448 PF00069 0.355
DOC_MAPK_gen_1 1563 1570 PF00069 0.315
DOC_MAPK_gen_1 1621 1630 PF00069 0.359
DOC_MAPK_gen_1 732 742 PF00069 0.416
DOC_MAPK_MEF2A_6 1307 1316 PF00069 0.257
DOC_MAPK_MEF2A_6 1440 1448 PF00069 0.331
DOC_MAPK_MEF2A_6 1563 1570 PF00069 0.310
DOC_MAPK_MEF2A_6 1641 1649 PF00069 0.257
DOC_MAPK_MEF2A_6 1673 1680 PF00069 0.468
DOC_MAPK_MEF2A_6 735 744 PF00069 0.368
DOC_MAPK_NFAT4_5 1673 1681 PF00069 0.467
DOC_PP1_RVXF_1 816 822 PF00149 0.359
DOC_PP2B_LxvP_1 1046 1049 PF13499 0.368
DOC_PP2B_LxvP_1 159 162 PF13499 0.534
DOC_PP2B_LxvP_1 1856 1859 PF13499 0.601
DOC_PP2B_LxvP_1 1922 1925 PF13499 0.593
DOC_PP2B_LxvP_1 413 416 PF13499 0.257
DOC_PP4_MxPP_1 1913 1916 PF00568 0.619
DOC_SPAK_OSR1_1 1486 1490 PF12202 0.359
DOC_USP7_MATH_1 1050 1054 PF00917 0.405
DOC_USP7_MATH_1 1088 1092 PF00917 0.359
DOC_USP7_MATH_1 1208 1212 PF00917 0.354
DOC_USP7_MATH_1 1289 1293 PF00917 0.359
DOC_USP7_MATH_1 138 142 PF00917 0.650
DOC_USP7_MATH_1 1455 1459 PF00917 0.257
DOC_USP7_MATH_1 1607 1611 PF00917 0.381
DOC_USP7_MATH_1 1712 1716 PF00917 0.547
DOC_USP7_MATH_1 1821 1825 PF00917 0.604
DOC_USP7_MATH_1 1830 1834 PF00917 0.733
DOC_USP7_MATH_1 1851 1855 PF00917 0.625
DOC_USP7_MATH_1 1925 1929 PF00917 0.614
DOC_USP7_MATH_1 215 219 PF00917 0.490
DOC_USP7_MATH_1 222 226 PF00917 0.521
DOC_USP7_MATH_1 276 280 PF00917 0.369
DOC_USP7_MATH_1 597 601 PF00917 0.484
DOC_USP7_MATH_1 69 73 PF00917 0.479
DOC_USP7_MATH_1 752 756 PF00917 0.313
DOC_USP7_MATH_1 802 806 PF00917 0.359
DOC_USP7_MATH_1 93 97 PF00917 0.584
DOC_USP7_MATH_1 970 974 PF00917 0.525
DOC_USP7_MATH_1 978 982 PF00917 0.553
DOC_USP7_MATH_1 995 999 PF00917 0.461
DOC_USP7_UBL2_3 188 192 PF12436 0.560
DOC_WW_Pin1_4 1099 1104 PF00397 0.319
DOC_WW_Pin1_4 1538 1543 PF00397 0.426
DOC_WW_Pin1_4 1571 1576 PF00397 0.359
DOC_WW_Pin1_4 1596 1601 PF00397 0.359
DOC_WW_Pin1_4 1707 1712 PF00397 0.563
DOC_WW_Pin1_4 1725 1730 PF00397 0.767
DOC_WW_Pin1_4 1807 1812 PF00397 0.677
DOC_WW_Pin1_4 1815 1820 PF00397 0.751
DOC_WW_Pin1_4 1826 1831 PF00397 0.532
DOC_WW_Pin1_4 1843 1848 PF00397 0.487
DOC_WW_Pin1_4 1849 1854 PF00397 0.542
DOC_WW_Pin1_4 1932 1937 PF00397 0.577
DOC_WW_Pin1_4 238 243 PF00397 0.674
DOC_WW_Pin1_4 272 277 PF00397 0.342
DOC_WW_Pin1_4 378 383 PF00397 0.492
DOC_WW_Pin1_4 600 605 PF00397 0.551
DOC_WW_Pin1_4 703 708 PF00397 0.509
DOC_WW_Pin1_4 854 859 PF00397 0.301
DOC_WW_Pin1_4 921 926 PF00397 0.481
DOC_WW_Pin1_4 966 971 PF00397 0.503
DOC_WW_Pin1_4 974 979 PF00397 0.518
LIG_14-3-3_CanoR_1 1040 1050 PF00244 0.433
LIG_14-3-3_CanoR_1 1054 1058 PF00244 0.281
LIG_14-3-3_CanoR_1 112 117 PF00244 0.579
LIG_14-3-3_CanoR_1 119 125 PF00244 0.527
LIG_14-3-3_CanoR_1 1209 1217 PF00244 0.421
LIG_14-3-3_CanoR_1 1265 1273 PF00244 0.274
LIG_14-3-3_CanoR_1 1342 1352 PF00244 0.397
LIG_14-3-3_CanoR_1 1385 1391 PF00244 0.383
LIG_14-3-3_CanoR_1 1395 1400 PF00244 0.359
LIG_14-3-3_CanoR_1 1412 1416 PF00244 0.359
LIG_14-3-3_CanoR_1 1567 1571 PF00244 0.359
LIG_14-3-3_CanoR_1 1608 1612 PF00244 0.416
LIG_14-3-3_CanoR_1 1673 1679 PF00244 0.441
LIG_14-3-3_CanoR_1 1900 1905 PF00244 0.563
LIG_14-3-3_CanoR_1 21 29 PF00244 0.581
LIG_14-3-3_CanoR_1 213 218 PF00244 0.416
LIG_14-3-3_CanoR_1 451 459 PF00244 0.405
LIG_14-3-3_CanoR_1 74 82 PF00244 0.486
LIG_14-3-3_CanoR_1 743 752 PF00244 0.331
LIG_14-3-3_CanoR_1 803 807 PF00244 0.422
LIG_14-3-3_CanoR_1 963 970 PF00244 0.538
LIG_14-3-3_CanoR_1 972 978 PF00244 0.508
LIG_Actin_WH2_2 1376 1393 PF00022 0.359
LIG_Actin_WH2_2 874 891 PF00022 0.257
LIG_AP_GAE_1 1868 1874 PF02883 0.529
LIG_APCC_ABBA_1 1415 1420 PF00400 0.257
LIG_BIR_II_1 1 5 PF00653 0.494
LIG_BIR_III_4 1720 1724 PF00653 0.527
LIG_BRCT_BRCA1_1 1092 1096 PF00533 0.359
LIG_BRCT_BRCA1_1 1363 1367 PF00533 0.330
LIG_BRCT_BRCA1_1 1616 1620 PF00533 0.359
LIG_BRCT_BRCA1_1 549 553 PF00533 0.481
LIG_BRCT_BRCA1_1 78 82 PF00533 0.432
LIG_BRCT_BRCA1_2 1092 1098 PF00533 0.274
LIG_CaM_IQ_9 1027 1042 PF13499 0.331
LIG_Clathr_ClatBox_1 1734 1738 PF01394 0.583
LIG_Clathr_ClatBox_1 1835 1839 PF01394 0.484
LIG_Clathr_ClatBox_1 420 424 PF01394 0.331
LIG_CtBP_PxDLS_1 68 74 PF00389 0.451
LIG_CtBP_PxDLS_1 711 715 PF00389 0.359
LIG_deltaCOP1_diTrp_1 1358 1367 PF00928 0.381
LIG_deltaCOP1_diTrp_1 507 514 PF00928 0.359
LIG_DLG_GKlike_1 547 555 PF00625 0.422
LIG_EH_1 1298 1302 PF12763 0.349
LIG_EH_1 1555 1559 PF12763 0.357
LIG_EH1_1 813 821 PF00400 0.331
LIG_EVH1_1 1046 1050 PF00568 0.331
LIG_EVH1_1 1856 1860 PF00568 0.538
LIG_EVH1_1 250 254 PF00568 0.569
LIG_FHA_1 1311 1317 PF00498 0.359
LIG_FHA_1 134 140 PF00498 0.492
LIG_FHA_1 148 154 PF00498 0.576
LIG_FHA_1 156 162 PF00498 0.568
LIG_FHA_1 1750 1756 PF00498 0.603
LIG_FHA_1 1764 1770 PF00498 0.615
LIG_FHA_1 1886 1892 PF00498 0.595
LIG_FHA_1 1893 1899 PF00498 0.573
LIG_FHA_1 226 232 PF00498 0.527
LIG_FHA_1 486 492 PF00498 0.373
LIG_FHA_1 49 55 PF00498 0.522
LIG_FHA_1 495 501 PF00498 0.323
LIG_FHA_1 515 521 PF00498 0.262
LIG_FHA_1 644 650 PF00498 0.441
LIG_FHA_1 707 713 PF00498 0.359
LIG_FHA_1 806 812 PF00498 0.387
LIG_FHA_1 883 889 PF00498 0.265
LIG_FHA_1 902 908 PF00498 0.305
LIG_FHA_1 963 969 PF00498 0.546
LIG_FHA_2 1218 1224 PF00498 0.390
LIG_FHA_2 1277 1283 PF00498 0.389
LIG_FHA_2 1288 1294 PF00498 0.455
LIG_FHA_2 1332 1338 PF00498 0.377
LIG_FHA_2 1342 1348 PF00498 0.446
LIG_FHA_2 1455 1461 PF00498 0.381
LIG_FHA_2 1545 1551 PF00498 0.274
LIG_FHA_2 1726 1732 PF00498 0.573
LIG_FHA_2 1788 1794 PF00498 0.553
LIG_FHA_2 184 190 PF00498 0.443
LIG_FHA_2 320 326 PF00498 0.257
LIG_FHA_2 364 370 PF00498 0.518
LIG_FHA_2 480 486 PF00498 0.350
LIG_FHA_2 570 576 PF00498 0.494
LIG_FHA_2 650 656 PF00498 0.564
LIG_FHA_2 807 813 PF00498 0.331
LIG_GBD_Chelix_1 1029 1037 PF00786 0.359
LIG_GBD_Chelix_1 816 824 PF00786 0.359
LIG_Integrin_isoDGR_2 1323 1325 PF01839 0.416
LIG_LIR_Apic_2 115 121 PF02991 0.475
LIG_LIR_Apic_2 705 711 PF02991 0.458
LIG_LIR_Gen_1 1120 1129 PF02991 0.331
LIG_LIR_Gen_1 1334 1341 PF02991 0.359
LIG_LIR_Gen_1 1358 1367 PF02991 0.439
LIG_LIR_Gen_1 611 621 PF02991 0.418
LIG_LIR_Gen_1 633 643 PF02991 0.437
LIG_LIR_Nem_3 1120 1125 PF02991 0.449
LIG_LIR_Nem_3 1129 1135 PF02991 0.356
LIG_LIR_Nem_3 123 129 PF02991 0.499
LIG_LIR_Nem_3 1334 1338 PF02991 0.379
LIG_LIR_Nem_3 1358 1363 PF02991 0.420
LIG_LIR_Nem_3 1398 1402 PF02991 0.376
LIG_LIR_Nem_3 1404 1410 PF02991 0.393
LIG_LIR_Nem_3 1461 1467 PF02991 0.328
LIG_LIR_Nem_3 1659 1665 PF02991 0.327
LIG_LIR_Nem_3 185 190 PF02991 0.584
LIG_LIR_Nem_3 1868 1874 PF02991 0.529
LIG_LIR_Nem_3 611 616 PF02991 0.470
LIG_LIR_Nem_3 618 624 PF02991 0.411
LIG_LIR_Nem_3 633 639 PF02991 0.463
LIG_LIR_Nem_3 713 719 PF02991 0.382
LIG_MYND_1 1917 1921 PF01753 0.664
LIG_MYND_3 1919 1923 PF01753 0.663
LIG_NRBOX 1263 1269 PF00104 0.359
LIG_NRBOX 1310 1316 PF00104 0.357
LIG_NRBOX 638 644 PF00104 0.448
LIG_NRP_CendR_1 1941 1942 PF00754 0.583
LIG_PCNA_yPIPBox_3 1307 1315 PF02747 0.358
LIG_Pex14_2 1407 1411 PF04695 0.381
LIG_Pex14_2 1558 1562 PF04695 0.357
LIG_Pex14_2 1616 1620 PF04695 0.416
LIG_Pex14_2 528 532 PF04695 0.405
LIG_Pex14_2 621 625 PF04695 0.434
LIG_PTAP_UEV_1 54 59 PF05743 0.515
LIG_PTB_Apo_2 829 836 PF02174 0.331
LIG_PTB_Phospho_1 829 835 PF10480 0.331
LIG_REV1ctd_RIR_1 1559 1568 PF16727 0.352
LIG_SH2_CRK 1043 1047 PF00017 0.359
LIG_SH2_CRK 118 122 PF00017 0.454
LIG_SH2_CRK 1387 1391 PF00017 0.359
LIG_SH2_CRK 1472 1476 PF00017 0.430
LIG_SH2_CRK 613 617 PF00017 0.407
LIG_SH2_GRB2like 1472 1475 PF00017 0.430
LIG_SH2_GRB2like 438 441 PF00017 0.257
LIG_SH2_GRB2like 610 613 PF00017 0.465
LIG_SH2_NCK_1 1589 1593 PF00017 0.357
LIG_SH2_NCK_1 847 851 PF00017 0.416
LIG_SH2_PTP2 636 639 PF00017 0.440
LIG_SH2_SRC 1402 1405 PF00017 0.359
LIG_SH2_SRC 1467 1470 PF00017 0.411
LIG_SH2_SRC 767 770 PF00017 0.359
LIG_SH2_SRC 787 790 PF00017 0.234
LIG_SH2_STAP1 157 161 PF00017 0.575
LIG_SH2_STAP1 847 851 PF00017 0.359
LIG_SH2_STAT3 1532 1535 PF00017 0.381
LIG_SH2_STAT3 157 160 PF00017 0.579
LIG_SH2_STAT5 1122 1125 PF00017 0.331
LIG_SH2_STAT5 1157 1160 PF00017 0.395
LIG_SH2_STAT5 1326 1329 PF00017 0.403
LIG_SH2_STAT5 1402 1405 PF00017 0.416
LIG_SH2_STAT5 1467 1470 PF00017 0.442
LIG_SH2_STAT5 1529 1532 PF00017 0.381
LIG_SH2_STAT5 1553 1556 PF00017 0.376
LIG_SH2_STAT5 157 160 PF00017 0.579
LIG_SH2_STAT5 1665 1668 PF00017 0.432
LIG_SH2_STAT5 362 365 PF00017 0.374
LIG_SH2_STAT5 419 422 PF00017 0.331
LIG_SH2_STAT5 472 475 PF00017 0.405
LIG_SH2_STAT5 480 483 PF00017 0.405
LIG_SH2_STAT5 636 639 PF00017 0.440
LIG_SH2_STAT5 708 711 PF00017 0.453
LIG_SH2_STAT5 716 719 PF00017 0.429
LIG_SH2_STAT5 720 723 PF00017 0.462
LIG_SH2_STAT5 767 770 PF00017 0.400
LIG_SH2_STAT5 787 790 PF00017 0.327
LIG_SH2_STAT5 847 850 PF00017 0.438
LIG_SH3_2 1049 1054 PF14604 0.257
LIG_SH3_3 1001 1007 PF00018 0.508
LIG_SH3_3 1044 1050 PF00018 0.441
LIG_SH3_3 1145 1151 PF00018 0.510
LIG_SH3_3 1250 1256 PF00018 0.359
LIG_SH3_3 1294 1300 PF00018 0.371
LIG_SH3_3 1378 1384 PF00018 0.310
LIG_SH3_3 1439 1445 PF00018 0.370
LIG_SH3_3 1808 1814 PF00018 0.723
LIG_SH3_3 1847 1853 PF00018 0.673
LIG_SH3_3 1854 1860 PF00018 0.605
LIG_SH3_3 1914 1920 PF00018 0.664
LIG_SH3_3 224 230 PF00018 0.561
LIG_SH3_3 234 240 PF00018 0.673
LIG_SH3_3 248 254 PF00018 0.721
LIG_SH3_3 291 297 PF00018 0.359
LIG_SH3_3 393 399 PF00018 0.257
LIG_SH3_3 52 58 PF00018 0.611
LIG_SH3_3 628 634 PF00018 0.462
LIG_SH3_3 922 928 PF00018 0.366
LIG_SH3_3 964 970 PF00018 0.533
LIG_SH3_3 972 978 PF00018 0.610
LIG_SUMO_SIM_anti_2 1309 1316 PF11976 0.359
LIG_SUMO_SIM_anti_2 761 766 PF11976 0.359
LIG_SUMO_SIM_par_1 1312 1319 PF11976 0.359
LIG_SUMO_SIM_par_1 1674 1679 PF11976 0.431
LIG_SUMO_SIM_par_1 1920 1930 PF11976 0.562
LIG_SUMO_SIM_par_1 419 424 PF11976 0.510
LIG_SUMO_SIM_par_1 494 501 PF11976 0.313
LIG_SUMO_SIM_par_1 709 715 PF11976 0.359
LIG_SUMO_SIM_par_1 761 766 PF11976 0.359
LIG_SUMO_SIM_par_1 919 924 PF11976 0.421
LIG_TRAF2_1 1334 1337 PF00917 0.359
LIG_TRAF2_1 1356 1359 PF00917 0.331
LIG_TRAF2_1 1457 1460 PF00917 0.315
LIG_TRAF2_1 1729 1732 PF00917 0.464
LIG_TRAF2_1 1903 1906 PF00917 0.549
LIG_TRAF2_1 873 876 PF00917 0.257
LIG_UBA3_1 1237 1244 PF00899 0.344
LIG_UBA3_1 1311 1317 PF00899 0.360
LIG_WRC_WIRS_1 1396 1401 PF05994 0.381
LIG_WRC_WIRS_1 1489 1494 PF05994 0.444
LIG_WRC_WIRS_1 520 525 PF05994 0.407
LIG_WRC_WIRS_1 871 876 PF05994 0.416
MOD_CDC14_SPxK_1 969 972 PF00782 0.511
MOD_CDK_SPK_2 1725 1730 PF00069 0.657
MOD_CDK_SPxK_1 966 972 PF00069 0.503
MOD_CDK_SPxxK_3 1099 1106 PF00069 0.314
MOD_CK1_1 103 109 PF00069 0.626
MOD_CK1_1 1053 1059 PF00069 0.347
MOD_CK1_1 1099 1105 PF00069 0.281
MOD_CK1_1 11 17 PF00069 0.543
MOD_CK1_1 1389 1395 PF00069 0.288
MOD_CK1_1 1488 1494 PF00069 0.331
MOD_CK1_1 151 157 PF00069 0.562
MOD_CK1_1 1541 1547 PF00069 0.437
MOD_CK1_1 1569 1575 PF00069 0.416
MOD_CK1_1 1590 1596 PF00069 0.359
MOD_CK1_1 1601 1607 PF00069 0.389
MOD_CK1_1 1614 1620 PF00069 0.369
MOD_CK1_1 1696 1702 PF00069 0.731
MOD_CK1_1 1715 1721 PF00069 0.748
MOD_CK1_1 1820 1826 PF00069 0.758
MOD_CK1_1 1829 1835 PF00069 0.549
MOD_CK1_1 1866 1872 PF00069 0.584
MOD_CK1_1 1927 1933 PF00069 0.603
MOD_CK1_1 2 8 PF00069 0.531
MOD_CK1_1 202 208 PF00069 0.722
MOD_CK1_1 225 231 PF00069 0.584
MOD_CK1_1 24 30 PF00069 0.619
MOD_CK1_1 378 384 PF00069 0.355
MOD_CK1_1 522 528 PF00069 0.434
MOD_CK1_1 600 606 PF00069 0.696
MOD_CK1_1 747 753 PF00069 0.359
MOD_CK1_1 805 811 PF00069 0.368
MOD_CK1_1 827 833 PF00069 0.378
MOD_CK1_1 86 92 PF00069 0.505
MOD_CK1_1 862 868 PF00069 0.333
MOD_CK1_1 901 907 PF00069 0.463
MOD_CK1_1 924 930 PF00069 0.381
MOD_CK1_1 96 102 PF00069 0.569
MOD_CK1_1 973 979 PF00069 0.562
MOD_CK2_1 1331 1337 PF00069 0.374
MOD_CK2_1 1341 1347 PF00069 0.387
MOD_CK2_1 1353 1359 PF00069 0.381
MOD_CK2_1 1395 1401 PF00069 0.377
MOD_CK2_1 1454 1460 PF00069 0.402
MOD_CK2_1 1492 1498 PF00069 0.422
MOD_CK2_1 1696 1702 PF00069 0.635
MOD_CK2_1 1725 1731 PF00069 0.594
MOD_CK2_1 1787 1793 PF00069 0.597
MOD_CK2_1 1900 1906 PF00069 0.534
MOD_CK2_1 2 8 PF00069 0.437
MOD_CK2_1 319 325 PF00069 0.257
MOD_CK2_1 355 361 PF00069 0.302
MOD_CK2_1 363 369 PF00069 0.338
MOD_CK2_1 459 465 PF00069 0.283
MOD_CK2_1 479 485 PF00069 0.368
MOD_CK2_1 600 606 PF00069 0.524
MOD_CK2_1 649 655 PF00069 0.479
MOD_CK2_1 807 813 PF00069 0.331
MOD_CK2_1 869 875 PF00069 0.377
MOD_Cter_Amidation 668 671 PF01082 0.527
MOD_GlcNHglycan 1 4 PF01048 0.480
MOD_GlcNHglycan 102 105 PF01048 0.746
MOD_GlcNHglycan 1098 1101 PF01048 0.386
MOD_GlcNHglycan 1355 1358 PF01048 0.359
MOD_GlcNHglycan 136 139 PF01048 0.654
MOD_GlcNHglycan 140 143 PF01048 0.794
MOD_GlcNHglycan 150 153 PF01048 0.748
MOD_GlcNHglycan 1523 1526 PF01048 0.349
MOD_GlcNHglycan 1633 1636 PF01048 0.359
MOD_GlcNHglycan 1666 1669 PF01048 0.431
MOD_GlcNHglycan 1695 1698 PF01048 0.689
MOD_GlcNHglycan 1715 1718 PF01048 0.512
MOD_GlcNHglycan 1819 1822 PF01048 0.794
MOD_GlcNHglycan 1853 1856 PF01048 0.692
MOD_GlcNHglycan 1865 1868 PF01048 0.568
MOD_GlcNHglycan 1871 1874 PF01048 0.652
MOD_GlcNHglycan 393 396 PF01048 0.489
MOD_GlcNHglycan 448 451 PF01048 0.396
MOD_GlcNHglycan 452 455 PF01048 0.383
MOD_GlcNHglycan 55 58 PF01048 0.603
MOD_GlcNHglycan 583 586 PF01048 0.582
MOD_GlcNHglycan 593 596 PF01048 0.748
MOD_GlcNHglycan 599 602 PF01048 0.693
MOD_GlcNHglycan 673 676 PF01048 0.557
MOD_GlcNHglycan 747 750 PF01048 0.555
MOD_GlcNHglycan 755 758 PF01048 0.293
MOD_GlcNHglycan 85 88 PF01048 0.642
MOD_GlcNHglycan 950 953 PF01048 0.615
MOD_GlcNHglycan 972 975 PF01048 0.532
MOD_GlcNHglycan 987 990 PF01048 0.472
MOD_GSK3_1 1086 1093 PF00069 0.343
MOD_GSK3_1 1114 1121 PF00069 0.530
MOD_GSK3_1 134 141 PF00069 0.575
MOD_GSK3_1 1341 1348 PF00069 0.359
MOD_GSK3_1 1366 1373 PF00069 0.394
MOD_GSK3_1 1385 1392 PF00069 0.519
MOD_GSK3_1 147 154 PF00069 0.637
MOD_GSK3_1 1488 1495 PF00069 0.380
MOD_GSK3_1 1607 1614 PF00069 0.344
MOD_GSK3_1 1689 1696 PF00069 0.568
MOD_GSK3_1 1712 1719 PF00069 0.548
MOD_GSK3_1 1803 1810 PF00069 0.725
MOD_GSK3_1 1817 1824 PF00069 0.601
MOD_GSK3_1 1826 1833 PF00069 0.622
MOD_GSK3_1 1859 1866 PF00069 0.586
MOD_GSK3_1 1894 1901 PF00069 0.557
MOD_GSK3_1 1923 1930 PF00069 0.630
MOD_GSK3_1 200 207 PF00069 0.592
MOD_GSK3_1 253 260 PF00069 0.733
MOD_GSK3_1 268 275 PF00069 0.404
MOD_GSK3_1 387 394 PF00069 0.468
MOD_GSK3_1 442 449 PF00069 0.318
MOD_GSK3_1 464 471 PF00069 0.326
MOD_GSK3_1 49 56 PF00069 0.537
MOD_GSK3_1 494 501 PF00069 0.398
MOD_GSK3_1 510 517 PF00069 0.414
MOD_GSK3_1 532 539 PF00069 0.397
MOD_GSK3_1 706 713 PF00069 0.431
MOD_GSK3_1 747 754 PF00069 0.314
MOD_GSK3_1 77 84 PF00069 0.506
MOD_GSK3_1 801 808 PF00069 0.352
MOD_GSK3_1 865 872 PF00069 0.423
MOD_GSK3_1 897 904 PF00069 0.357
MOD_GSK3_1 96 103 PF00069 0.570
MOD_GSK3_1 962 969 PF00069 0.539
MOD_GSK3_1 970 977 PF00069 0.527
MOD_N-GLC_1 1114 1119 PF02516 0.487
MOD_N-GLC_1 1197 1202 PF02516 0.359
MOD_N-GLC_1 147 152 PF02516 0.602
MOD_N-GLC_1 1544 1549 PF02516 0.401
MOD_N-GLC_1 1614 1619 PF02516 0.357
MOD_N-GLC_1 1636 1641 PF02516 0.349
MOD_N-GLC_1 1693 1698 PF02516 0.546
MOD_N-GLC_1 1807 1812 PF02516 0.681
MOD_N-GLC_1 446 451 PF02516 0.274
MOD_N-GLC_1 752 757 PF02516 0.342
MOD_N-GLC_1 82 87 PF02516 0.436
MOD_N-GLC_2 340 342 PF02516 0.359
MOD_N-GLC_2 724 726 PF02516 0.359
MOD_NEK2_1 1096 1101 PF00069 0.333
MOD_NEK2_1 1203 1208 PF00069 0.341
MOD_NEK2_1 1216 1221 PF00069 0.359
MOD_NEK2_1 1345 1350 PF00069 0.342
MOD_NEK2_1 1372 1377 PF00069 0.395
MOD_NEK2_1 1521 1526 PF00069 0.405
MOD_NEK2_1 1566 1571 PF00069 0.416
MOD_NEK2_1 1630 1635 PF00069 0.378
MOD_NEK2_1 1724 1729 PF00069 0.486
MOD_NEK2_1 1764 1769 PF00069 0.615
MOD_NEK2_1 183 188 PF00069 0.535
MOD_NEK2_1 1898 1903 PF00069 0.583
MOD_NEK2_1 387 392 PF00069 0.341
MOD_NEK2_1 446 451 PF00069 0.355
MOD_NEK2_1 459 464 PF00069 0.494
MOD_NEK2_1 48 53 PF00069 0.561
MOD_NEK2_1 498 503 PF00069 0.369
MOD_NEK2_1 583 588 PF00069 0.606
MOD_NEK2_1 625 630 PF00069 0.473
MOD_NEK2_1 643 648 PF00069 0.475
MOD_NEK2_1 660 665 PF00069 0.612
MOD_NEK2_1 763 768 PF00069 0.343
MOD_NEK2_1 77 82 PF00069 0.542
MOD_NEK2_1 806 811 PF00069 0.367
MOD_NEK2_1 824 829 PF00069 0.366
MOD_NEK2_2 1411 1416 PF00069 0.441
MOD_NEK2_2 215 220 PF00069 0.419
MOD_NEK2_2 69 74 PF00069 0.445
MOD_OFUCOSY 293 299 PF10250 0.359
MOD_OFUCOSY 342 347 PF10250 0.331
MOD_PIKK_1 104 110 PF00454 0.574
MOD_PIKK_1 1086 1092 PF00454 0.343
MOD_PIKK_1 1578 1584 PF00454 0.407
MOD_PIKK_1 1796 1802 PF00454 0.626
MOD_PIKK_1 1822 1828 PF00454 0.707
MOD_PIKK_1 1927 1933 PF00454 0.605
MOD_PIKK_1 225 231 PF00454 0.532
MOD_PIKK_1 464 470 PF00454 0.257
MOD_PIKK_1 836 842 PF00454 0.333
MOD_PIKK_1 979 985 PF00454 0.510
MOD_PIKK_1 995 1001 PF00454 0.464
MOD_PK_1 1485 1491 PF00069 0.359
MOD_PK_1 1900 1906 PF00069 0.534
MOD_PK_1 213 219 PF00069 0.417
MOD_PKA_1 1485 1491 PF00069 0.359
MOD_PKA_1 671 677 PF00069 0.439
MOD_PKA_2 1053 1059 PF00069 0.355
MOD_PKA_2 111 117 PF00069 0.579
MOD_PKA_2 1208 1214 PF00069 0.416
MOD_PKA_2 134 140 PF00069 0.522
MOD_PKA_2 1341 1347 PF00069 0.472
MOD_PKA_2 1411 1417 PF00069 0.359
MOD_PKA_2 1485 1491 PF00069 0.359
MOD_PKA_2 1492 1498 PF00069 0.359
MOD_PKA_2 1566 1572 PF00069 0.359
MOD_PKA_2 1607 1613 PF00069 0.436
MOD_PKA_2 1785 1791 PF00069 0.514
MOD_PKA_2 183 189 PF00069 0.516
MOD_PKA_2 1899 1905 PF00069 0.558
MOD_PKA_2 22 28 PF00069 0.498
MOD_PKA_2 225 231 PF00069 0.584
MOD_PKA_2 450 456 PF00069 0.400
MOD_PKA_2 468 474 PF00069 0.389
MOD_PKA_2 671 677 PF00069 0.454
MOD_PKA_2 75 81 PF00069 0.482
MOD_PKA_2 802 808 PF00069 0.400
MOD_PKA_2 962 968 PF00069 0.731
MOD_PKB_1 110 118 PF00069 0.530
MOD_PKB_1 21 29 PF00069 0.520
MOD_PKB_1 74 82 PF00069 0.428
MOD_Plk_1 148 154 PF00069 0.759
MOD_Plk_1 1587 1593 PF00069 0.378
MOD_Plk_1 1614 1620 PF00069 0.352
MOD_Plk_1 494 500 PF00069 0.383
MOD_Plk_1 567 573 PF00069 0.600
MOD_Plk_1 685 691 PF00069 0.362
MOD_Plk_1 758 764 PF00069 0.359
MOD_Plk_1 862 868 PF00069 0.277
MOD_Plk_1 897 903 PF00069 0.425
MOD_Plk_2-3 1276 1282 PF00069 0.331
MOD_Plk_2-3 1341 1347 PF00069 0.381
MOD_Plk_2-3 1498 1504 PF00069 0.333
MOD_Plk_4 1053 1059 PF00069 0.475
MOD_Plk_4 1080 1086 PF00069 0.257
MOD_Plk_4 1118 1124 PF00069 0.306
MOD_Plk_4 120 126 PF00069 0.570
MOD_Plk_4 1310 1316 PF00069 0.369
MOD_Plk_4 1607 1613 PF00069 0.357
MOD_Plk_4 1894 1900 PF00069 0.580
MOD_Plk_4 215 221 PF00069 0.420
MOD_Plk_4 355 361 PF00069 0.309
MOD_Plk_4 468 474 PF00069 0.257
MOD_Plk_4 510 516 PF00069 0.351
MOD_Plk_4 712 718 PF00069 0.310
MOD_Plk_4 758 764 PF00069 0.345
MOD_Plk_4 77 83 PF00069 0.433
MOD_ProDKin_1 1099 1105 PF00069 0.319
MOD_ProDKin_1 1538 1544 PF00069 0.426
MOD_ProDKin_1 1571 1577 PF00069 0.359
MOD_ProDKin_1 1596 1602 PF00069 0.359
MOD_ProDKin_1 1707 1713 PF00069 0.559
MOD_ProDKin_1 1725 1731 PF00069 0.765
MOD_ProDKin_1 1807 1813 PF00069 0.678
MOD_ProDKin_1 1815 1821 PF00069 0.751
MOD_ProDKin_1 1826 1832 PF00069 0.530
MOD_ProDKin_1 1843 1849 PF00069 0.491
MOD_ProDKin_1 1932 1938 PF00069 0.576
MOD_ProDKin_1 238 244 PF00069 0.675
MOD_ProDKin_1 272 278 PF00069 0.342
MOD_ProDKin_1 378 384 PF00069 0.492
MOD_ProDKin_1 600 606 PF00069 0.552
MOD_ProDKin_1 703 709 PF00069 0.498
MOD_ProDKin_1 854 860 PF00069 0.301
MOD_ProDKin_1 921 927 PF00069 0.477
MOD_ProDKin_1 966 972 PF00069 0.506
MOD_ProDKin_1 974 980 PF00069 0.520
MOD_SUMO_for_1 1620 1623 PF00179 0.359
MOD_SUMO_for_1 1729 1732 PF00179 0.481
MOD_SUMO_rev_2 1062 1071 PF00179 0.331
MOD_SUMO_rev_2 1617 1625 PF00179 0.359
MOD_SUMO_rev_2 271 276 PF00179 0.395
MOD_SUMO_rev_2 632 637 PF00179 0.443
MOD_SUMO_rev_2 872 881 PF00179 0.359
MOD_SUMO_rev_2 912 921 PF00179 0.359
TRG_DiLeu_BaEn_1 1166 1171 PF01217 0.359
TRG_DiLeu_BaEn_1 1310 1315 PF01217 0.359
TRG_DiLeu_BaEn_1 1358 1363 PF01217 0.331
TRG_DiLeu_BaEn_1 917 922 PF01217 0.331
TRG_DiLeu_BaEn_4 1358 1364 PF01217 0.331
TRG_DiLeu_BaEn_4 311 317 PF01217 0.359
TRG_DiLeu_BaLyEn_6 1572 1577 PF01217 0.387
TRG_DiLeu_BaLyEn_6 1581 1586 PF01217 0.374
TRG_DiLeu_BaLyEn_6 173 178 PF01217 0.580
TRG_DiLeu_BaLyEn_6 1760 1765 PF01217 0.578
TRG_DiLeu_BaLyEn_6 1887 1892 PF01217 0.562
TRG_DiLeu_BaLyEn_6 815 820 PF01217 0.359
TRG_DiLeu_BaLyEn_6 839 844 PF01217 0.359
TRG_DiLeu_LyEn_5 1166 1171 PF01217 0.268
TRG_ENDOCYTIC_2 1002 1005 PF00928 0.548
TRG_ENDOCYTIC_2 1043 1046 PF00928 0.344
TRG_ENDOCYTIC_2 1122 1125 PF00928 0.462
TRG_ENDOCYTIC_2 1132 1135 PF00928 0.284
TRG_ENDOCYTIC_2 1157 1160 PF00928 0.370
TRG_ENDOCYTIC_2 1387 1390 PF00928 0.416
TRG_ENDOCYTIC_2 1472 1475 PF00928 0.446
TRG_ENDOCYTIC_2 187 190 PF00928 0.603
TRG_ENDOCYTIC_2 439 442 PF00928 0.366
TRG_ENDOCYTIC_2 613 616 PF00928 0.413
TRG_ENDOCYTIC_2 636 639 PF00928 0.468
TRG_ER_diArg_1 110 113 PF00400 0.567
TRG_ER_diArg_1 1167 1169 PF00400 0.406
TRG_ER_diArg_1 1181 1183 PF00400 0.300
TRG_ER_diArg_1 1440 1442 PF00400 0.400
TRG_ER_diArg_1 1481 1484 PF00400 0.359
TRG_ER_diArg_1 1485 1487 PF00400 0.234
TRG_ER_diArg_1 1562 1564 PF00400 0.303
TRG_ER_diArg_1 1741 1744 PF00400 0.482
TRG_ER_diArg_1 1782 1784 PF00400 0.675
TRG_ER_diArg_1 181 184 PF00400 0.578
TRG_ER_diArg_1 1874 1877 PF00400 0.542
TRG_ER_diArg_1 1889 1891 PF00400 0.555
TRG_ER_diArg_1 331 333 PF00400 0.343
TRG_ER_diArg_1 699 702 PF00400 0.552
TRG_ER_diArg_1 731 734 PF00400 0.416
TRG_ER_diArg_1 74 77 PF00400 0.519
TRG_NES_CRM1_1 1262 1276 PF08389 0.331
TRG_Pf-PMV_PEXEL_1 1168 1172 PF00026 0.345
TRG_Pf-PMV_PEXEL_1 1265 1270 PF00026 0.359
TRG_Pf-PMV_PEXEL_1 1746 1750 PF00026 0.576
TRG_Pf-PMV_PEXEL_1 365 369 PF00026 0.257

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HSA4 Leptomonas seymouri 65% 92%
A0A3Q8IIT0 Leishmania donovani 38% 100%
A0A3S5H592 Leishmania donovani 76% 98%
A4HNE4 Leishmania braziliensis 39% 100%
A4HS23 Leishmania infantum 78% 100%
A4IC17 Leishmania infantum 38% 100%
D0A6M8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 27% 100%
E9AFV5 Leishmania major 39% 100%
E9AK10 Leishmania mexicana (strain MHOM/GT/2001/U1103) 75% 96%
E9APC2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 27% 100%
Q4QG56 Leishmania major 27% 100%
Q9XZY8 Leishmania major 76% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS