RNA pseudouridylate synthase-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

RNA pseudouridylate synthase-like protein

Species:

Leishmania braziliensis

UniProt:

A4H3U5_LEIBR

TriTrypDb:

LbrM.04.0290 , LBRM2903_040007500

Length:

1340

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H3U5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Show entries

Biological processes
Term	Name	Level	Count
GO:0000154	rRNA modification	6	1
GO:0000455	enzyme-directed rRNA pseudouridine synthesis	8	1
GO:0001522	pseudouridine synthesis	6	7
GO:0006139	nucleobase-containing compound metabolic process	3	7
GO:0006364	rRNA processing	8	1
GO:0006396	RNA processing	6	1
GO:0006725	cellular aromatic compound metabolic process	3	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0008152	metabolic process	1	7
GO:0009451	RNA modification	5	7

Previous1 2 3Next

Show entries

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	7
GO:0003723	RNA binding	4	7
GO:0003824	catalytic activity	1	7
GO:0005488	binding	1	7
GO:0009982	pseudouridine synthase activity	4	7
GO:0016853	isomerase activity	2	7
GO:0016866	intramolecular transferase activity	3	7
GO:0097159	organic cyclic compound binding	2	7
GO:1901363	heterocyclic compound binding	2	7

Previous1Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1015	1019	PF00656	0.438
CLV_C14_Caspase3-7	1286	1290	PF00656	0.590
CLV_C14_Caspase3-7	183	187	PF00656	0.711
CLV_C14_Caspase3-7	23	27	PF00656	0.440
CLV_C14_Caspase3-7	664	668	PF00656	0.472
CLV_C14_Caspase3-7	673	677	PF00656	0.446
CLV_C14_Caspase3-7	784	788	PF00656	0.540
CLV_C14_Caspase3-7	949	953	PF00656	0.537
CLV_NRD_NRD_1	1077	1079	PF00675	0.345
CLV_NRD_NRD_1	1234	1236	PF00675	0.346

Previous1 2 3 4 5…45Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBF4	Leptomonas seymouri	41%	97%
A0A451EJX2	Leishmania donovani	74%	91%
A4HS20	Leishmania infantum	74%	91%
E9AK07	Leishmania mexicana (strain MHOM/GT/2001/U1103)	73%	92%
Q9U190	Leishmania major	73%	100%

Previous1Next