LeishMANIAdb
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BZIP domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
BZIP domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4H3T4_LEIBR
TriTrypDb:
LbrM.04.0180 , LBRM2903_040006600
Length:
158

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H3T4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H3T4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 118 120 PF00675 0.532
CLV_NRD_NRD_1 127 129 PF00675 0.533
CLV_PCSK_KEX2_1 118 120 PF00082 0.532
CLV_PCSK_SKI1_1 133 137 PF00082 0.490
CLV_PCSK_SKI1_1 63 67 PF00082 0.451
DOC_CYCLIN_RxL_1 60 69 PF00134 0.567
DOC_MAPK_gen_1 133 141 PF00069 0.616
DOC_PP2B_LxvP_1 15 18 PF13499 0.583
DOC_USP7_MATH_1 72 76 PF00917 0.634
DOC_USP7_MATH_1 77 81 PF00917 0.639
DOC_USP7_MATH_1 94 98 PF00917 0.444
DOC_USP7_UBL2_3 129 133 PF12436 0.492
DOC_WW_Pin1_4 41 46 PF00397 0.716
LIG_14-3-3_CanoR_1 102 111 PF00244 0.496
LIG_FHA_1 134 140 PF00498 0.613
LIG_FHA_1 31 37 PF00498 0.603
LIG_FHA_1 59 65 PF00498 0.454
LIG_LIR_Gen_1 19 28 PF02991 0.460
LIG_LIR_Gen_1 3 11 PF02991 0.412
LIG_LIR_Nem_3 19 25 PF02991 0.477
LIG_LIR_Nem_3 3 7 PF02991 0.412
LIG_LIR_Nem_3 59 65 PF02991 0.498
LIG_SH2_CRK 22 26 PF00017 0.539
LIG_SH2_GRB2like 10 13 PF00017 0.418
LIG_SH2_SRC 10 13 PF00017 0.535
LIG_SH2_STAT5 10 13 PF00017 0.418
LIG_SH3_3 90 96 PF00018 0.625
MOD_CK1_1 37 43 PF00069 0.672
MOD_CK1_1 57 63 PF00069 0.335
MOD_CK1_1 79 85 PF00069 0.641
MOD_GlcNHglycan 28 31 PF01048 0.753
MOD_GlcNHglycan 36 39 PF01048 0.662
MOD_GlcNHglycan 50 54 PF01048 0.413
MOD_GlcNHglycan 74 77 PF01048 0.601
MOD_GlcNHglycan 79 82 PF01048 0.611
MOD_GSK3_1 139 146 PF00069 0.638
MOD_GSK3_1 26 33 PF00069 0.600
MOD_GSK3_1 37 44 PF00069 0.653
MOD_GSK3_1 54 61 PF00069 0.482
MOD_GSK3_1 72 79 PF00069 0.472
MOD_PIKK_1 2 8 PF00454 0.439
MOD_PKA_1 133 139 PF00069 0.492
MOD_PKA_2 77 83 PF00069 0.695
MOD_Plk_1 2 8 PF00069 0.415
MOD_Plk_1 49 55 PF00069 0.476
MOD_Plk_1 58 64 PF00069 0.413
MOD_ProDKin_1 41 47 PF00069 0.710
TRG_ENDOCYTIC_2 22 25 PF00928 0.569
TRG_ER_diArg_1 117 119 PF00400 0.529
TRG_ER_diArg_1 154 157 PF00400 0.624

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P3X6 Leptomonas seymouri 75% 99%
A0A1X0NLW6 Trypanosomatidae 45% 100%
A0A3S5H579 Leishmania donovani 89% 100%
A0A422NND8 Trypanosoma rangeli 47% 100%
A4HS09 Leishmania infantum 89% 100%
C9ZY07 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 46% 100%
E9ACP6 Leishmania major 90% 100%
E9AJZ7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS