LeishMANIAdb
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Coiled-coil domain-containing protein 177

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Coiled-coil domain-containing protein 177
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4H3S6_LEIBR
TriTrypDb:
LbrM.04.0100 , LBRM2903_040005800
Length:
549

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 9
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H3S6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H3S6

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 173 175 PF00675 0.673
CLV_NRD_NRD_1 244 246 PF00675 0.520
CLV_NRD_NRD_1 257 259 PF00675 0.443
CLV_NRD_NRD_1 336 338 PF00675 0.579
CLV_NRD_NRD_1 446 448 PF00675 0.517
CLV_NRD_NRD_1 453 455 PF00675 0.477
CLV_NRD_NRD_1 460 462 PF00675 0.471
CLV_NRD_NRD_1 474 476 PF00675 0.526
CLV_NRD_NRD_1 517 519 PF00675 0.646
CLV_PCSK_FUR_1 174 178 PF00082 0.511
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3S5H573 Leishmania donovani 58% 100%
A4HS01 Leishmania infantum 58% 100%
E9AJY9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 54% 100%
Q95Z90 Leishmania major 57% 95%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS