LeishMANIAdb
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Replicative DNA helicase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Replicative DNA helicase
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4H3N7_LEIBR
TriTrypDb:
LbrM.03.0660 , LBRM2903_030012500 *
Length:
99

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H3N7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H3N7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 59 61 PF00675 0.814
CLV_PCSK_SKI1_1 53 57 PF00082 0.770
DEG_Nend_UBRbox_3 1 3 PF02207 0.743
DOC_USP7_UBL2_3 61 65 PF12436 0.797
LIG_14-3-3_CanoR_1 67 75 PF00244 0.754
LIG_FHA_1 41 47 PF00498 0.746
LIG_NRBOX 47 53 PF00104 0.758
LIG_SH2_PTP2 34 37 PF00017 0.708
LIG_SH2_STAT5 24 27 PF00017 0.716
LIG_SH2_STAT5 34 37 PF00017 0.533
LIG_SH2_STAT5 78 81 PF00017 0.704
LIG_UBA3_1 51 58 PF00899 0.768
MOD_CK2_1 33 39 PF00069 0.713
MOD_NEK2_1 33 38 PF00069 0.709
MOD_NEK2_1 90 95 PF00069 0.790
MOD_PK_1 42 48 PF00069 0.748
MOD_PKA_2 66 72 PF00069 0.766
TRG_DiLeu_BaEn_1 47 52 PF01217 0.756
TRG_ENDOCYTIC_2 34 37 PF00928 0.708
TRG_Pf-PMV_PEXEL_1 8 12 PF00026 0.736

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS