Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania braziliensis

UniProt:

A4H3I9_LEIBR

TriTrypDb:

LbrM.03.0180 , LBRM2903_030006700

Length:

192

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H3I9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H3I9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	129	133	PF00656	0.586
CLV_C14_Caspase3-7	148	152	PF00656	0.528
CLV_C14_Caspase3-7	155	159	PF00656	0.511
CLV_C14_Caspase3-7	70	74	PF00656	0.810
CLV_C14_Caspase3-7	88	92	PF00656	0.428
CLV_NRD_NRD_1	186	188	PF00675	0.537
CLV_PCSK_SKI1_1	139	143	PF00082	0.631
DOC_PP4_MxPP_1	55	58	PF00568	0.512
DOC_USP7_MATH_1	109	113	PF00917	0.460
DOC_USP7_MATH_1	115	119	PF00917	0.466
DOC_USP7_MATH_1	64	68	PF00917	0.707
DOC_USP7_MATH_1	75	79	PF00917	0.704
DOC_USP7_MATH_1	83	87	PF00917	0.636
DOC_WW_Pin1_4	140	145	PF00397	0.635
LIG_14-3-3_CanoR_1	76	81	PF00244	0.565
LIG_BIR_II_1	1	5	PF00653	0.789
LIG_CtBP_PxDLS_1	167	171	PF00389	0.742
LIG_FHA_1	47	53	PF00498	0.777
LIG_FHA_1	7	13	PF00498	0.658
LIG_FHA_2	146	152	PF00498	0.530
LIG_FHA_2	18	24	PF00498	0.460
LIG_LIR_Nem_3	48	53	PF02991	0.783
LIG_PCNA_yPIPBox_3	94	108	PF02747	0.575
LIG_SH2_SRC	100	103	PF00017	0.688
LIG_SH2_STAT5	100	103	PF00017	0.688
LIG_SUMO_SIM_anti_2	169	175	PF11976	0.518
LIG_TRAF2_1	45	48	PF00917	0.767
MOD_CDK_SPxK_1	140	146	PF00069	0.637
MOD_CK1_1	3	9	PF00069	0.747
MOD_CK1_1	79	85	PF00069	0.589
MOD_CK1_1	86	92	PF00069	0.671
MOD_CK2_1	115	121	PF00069	0.497
MOD_CK2_1	17	23	PF00069	0.472
MOD_CK2_1	64	70	PF00069	0.549
MOD_GlcNHglycan	154	157	PF01048	0.671
MOD_GlcNHglycan	66	69	PF01048	0.766
MOD_GlcNHglycan	81	84	PF01048	0.527
MOD_GSK3_1	117	124	PF00069	0.727
MOD_GSK3_1	13	20	PF00069	0.548
MOD_GSK3_1	3	10	PF00069	0.642
MOD_GSK3_1	58	65	PF00069	0.793
MOD_GSK3_1	75	82	PF00069	0.518
MOD_GSK3_1	83	90	PF00069	0.671
MOD_N-GLC_1	121	126	PF02516	0.527
MOD_N-GLC_1	152	157	PF02516	0.540
MOD_N-GLC_1	35	40	PF02516	0.751
MOD_NEK2_1	4	9	PF00069	0.523
MOD_PKA_2	75	81	PF00069	0.816
MOD_Plk_4	17	23	PF00069	0.666
MOD_ProDKin_1	140	146	PF00069	0.637
MOD_SUMO_rev_2	132	140	PF00179	0.549
MOD_SUMO_rev_2	154	162	PF00179	0.534
MOD_SUMO_rev_2	23	29	PF00179	0.434
MOD_SUMO_rev_2	38	45	PF00179	0.501

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A451EJM2	Leishmania donovani	62%	100%
A4HRS8	Leishmania infantum	62%	100%
E9ACG4	Leishmania major	65%	100%
E9AJQ2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	65%	99%