LeishMANIAdb
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Transposase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Transposase
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
A4H3I6_LEIBR
TriTrypDb:
LbrM.03.0150 , LBRM2903_030006400 *
Length:
139

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H3I6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H3I6

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 88 92 PF00656 0.510
CLV_NRD_NRD_1 110 112 PF00675 0.695
CLV_NRD_NRD_1 122 124 PF00675 0.455
CLV_NRD_NRD_1 32 34 PF00675 0.585
CLV_NRD_NRD_1 55 57 PF00675 0.479
CLV_PCSK_FUR_1 108 112 PF00082 0.699
CLV_PCSK_FUR_1 120 124 PF00082 0.448
CLV_PCSK_KEX2_1 110 112 PF00082 0.672
CLV_PCSK_KEX2_1 122 124 PF00082 0.605
CLV_PCSK_KEX2_1 31 33 PF00082 0.599
CLV_PCSK_KEX2_1 55 57 PF00082 0.479
CLV_PCSK_PC1ET2_1 31 33 PF00082 0.628
CLV_PCSK_SKI1_1 111 115 PF00082 0.590
DEG_APCC_DBOX_1 110 118 PF00400 0.660
DEG_Nend_UBRbox_1 1 4 PF02207 0.621
DOC_MAPK_gen_1 120 129 PF00069 0.594
DOC_MAPK_MEF2A_6 62 69 PF00069 0.639
DOC_MAPK_NFAT4_5 62 70 PF00069 0.713
DOC_USP7_MATH_1 85 89 PF00917 0.695
DOC_USP7_MATH_1 92 96 PF00917 0.767
LIG_Dynein_DLC8_1 101 107 PF01221 0.491
LIG_FHA_2 23 29 PF00498 0.619
LIG_LIR_Gen_1 38 48 PF02991 0.620
LIG_LIR_Nem_3 38 44 PF02991 0.577
LIG_SH2_CRK 23 27 PF00017 0.716
LIG_SH2_STAT5 13 16 PF00017 0.612
LIG_SH2_STAT5 43 46 PF00017 0.647
LIG_TRAF2_1 113 116 PF00917 0.653
MOD_CK1_1 6 12 PF00069 0.587
MOD_CK2_1 87 93 PF00069 0.643
MOD_CK2_1 96 102 PF00069 0.639
MOD_GlcNHglycan 5 8 PF01048 0.588
MOD_GlcNHglycan 87 90 PF01048 0.704
MOD_GSK3_1 92 99 PF00069 0.753
MOD_PIKK_1 133 139 PF00454 0.702
MOD_PIKK_1 96 102 PF00454 0.730
MOD_PKA_2 102 108 PF00069 0.585
MOD_PKA_2 9 15 PF00069 0.579
MOD_Plk_2-3 87 93 PF00069 0.490
MOD_Plk_4 9 15 PF00069 0.616
TRG_ENDOCYTIC_2 23 26 PF00928 0.751
TRG_ER_diArg_1 54 56 PF00400 0.628
TRG_ER_diArg_1 62 65 PF00400 0.621
TRG_Pf-PMV_PEXEL_1 132 137 PF00026 0.572

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IJS5 Leptomonas seymouri 60% 97%
A0A0S4JDM7 Bodo saltans 42% 100%
A0A1X0P8N0 Trypanosomatidae 43% 100%
A0A422N7L0 Trypanosoma rangeli 42% 100%
A0A451EJL9 Leishmania donovani 79% 100%
D0A221 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 42% 100%
E9ACG1 Leishmania major 80% 100%
E9AG33 Leishmania infantum 80% 100%
E9AJP9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 78% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS