Organ specific protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

repeat gene hypothetical protein

Species:

Leishmania braziliensis

UniProt:

A4H3H0_LEIBR

TriTrypDb:

LbrM.02.0770

Length:

399

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H3H0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H3H0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	140	144	PF00656	0.743
CLV_C14_Caspase3-7	234	238	PF00656	0.732
CLV_C14_Caspase3-7	332	336	PF00656	0.635
CLV_NRD_NRD_1	134	136	PF00675	0.722
CLV_PCSK_KEX2_1	136	138	PF00082	0.742
CLV_PCSK_KEX2_1	242	244	PF00082	0.742
CLV_PCSK_KEX2_1	340	342	PF00082	0.639
CLV_PCSK_KEX2_1	46	48	PF00082	0.738
CLV_PCSK_PC1ET2_1	136	138	PF00082	0.742
CLV_PCSK_PC1ET2_1	242	244	PF00082	0.742
CLV_PCSK_PC1ET2_1	340	342	PF00082	0.639
CLV_PCSK_PC1ET2_1	46	48	PF00082	0.738
CLV_PCSK_SKI1_1	102	106	PF00082	0.709
CLV_PCSK_SKI1_1	200	204	PF00082	0.707
CLV_PCSK_SKI1_1	298	302	PF00082	0.820
DOC_MAPK_gen_1	189	199	PF00069	0.711
DOC_MAPK_gen_1	285	297	PF00069	0.710
DOC_MAPK_gen_1	383	395	PF00069	0.598
DOC_MAPK_gen_1	91	101	PF00069	0.706
DOC_USP7_MATH_1	119	123	PF00917	0.702
DOC_USP7_UBL2_3	286	290	PF12436	0.705
DOC_USP7_UBL2_3	384	388	PF12436	0.590
DOC_WW_Pin1_4	130	135	PF00397	0.695
DOC_WW_Pin1_4	228	233	PF00397	0.715
DOC_WW_Pin1_4	32	37	PF00397	0.709
DOC_WW_Pin1_4	326	331	PF00397	0.716
LIG_FHA_1	105	111	PF00498	0.604
LIG_FHA_1	7	13	PF00498	0.679
LIG_LIR_Apic_2	128	134	PF02991	0.693
LIG_PTB_Apo_2	170	177	PF02174	0.695
LIG_PTB_Apo_2	268	275	PF02174	0.697
LIG_PTB_Apo_2	72	79	PF02174	0.683
LIG_SH2_CRK	131	135	PF00017	0.695
LIG_SH2_SRC	167	170	PF00017	0.695
LIG_SH2_SRC	222	225	PF00017	0.701
LIG_SH2_SRC	26	29	PF00017	0.698
LIG_SH2_SRC	265	268	PF00017	0.700
LIG_SH2_SRC	363	366	PF00017	0.596
LIG_SH2_SRC	69	72	PF00017	0.689
LIG_SH2_STAP1	167	171	PF00017	0.694
LIG_SH2_STAP1	265	269	PF00017	0.698
LIG_SH2_STAP1	363	367	PF00017	0.593
LIG_SH2_STAP1	69	73	PF00017	0.685
LIG_SH2_STAT5	124	127	PF00017	0.718
LIG_SH2_STAT5	185	188	PF00017	0.719
LIG_SH2_STAT5	222	225	PF00017	0.701
LIG_SH2_STAT5	26	29	PF00017	0.698
LIG_SH2_STAT5	283	286	PF00017	0.718
LIG_SH2_STAT5	320	323	PF00017	0.722
LIG_SH2_STAT5	381	384	PF00017	0.604
LIG_SH2_STAT5	87	90	PF00017	0.711
LIG_SUMO_SIM_par_1	107	113	PF11976	0.606
LIG_SUMO_SIM_par_1	9	15	PF11976	0.681
LIG_TRAF2_1	127	130	PF00917	0.710
LIG_TRAF2_1	225	228	PF00917	0.706
LIG_TRAF2_1	29	32	PF00917	0.699
LIG_TRAF2_1	323	326	PF00917	0.724
MOD_CDC14_SPxK_1	133	136	PF00782	0.714
MOD_CDK_SPK_2	130	135	PF00069	0.695
MOD_CDK_SPK_2	228	233	PF00069	0.715
MOD_CDK_SPK_2	32	37	PF00069	0.709
MOD_CDK_SPK_2	326	331	PF00069	0.716
MOD_CDK_SPxK_1	130	136	PF00069	0.700
MOD_CDK_SPxxK_3	130	137	PF00069	0.707
MOD_CDK_SPxxK_3	228	235	PF00069	0.722
MOD_CDK_SPxxK_3	32	39	PF00069	0.716
MOD_CDK_SPxxK_3	326	333	PF00069	0.722
MOD_CK2_1	124	130	PF00069	0.714
MOD_CK2_1	222	228	PF00069	0.705
MOD_CK2_1	26	32	PF00069	0.699
MOD_CK2_1	320	326	PF00069	0.722
MOD_GlcNHglycan	116	119	PF01048	0.696
MOD_GlcNHglycan	312	315	PF01048	0.706
MOD_GSK3_1	104	111	PF00069	0.705
MOD_GSK3_1	148	155	PF00069	0.735
MOD_GSK3_1	202	209	PF00069	0.705
MOD_GSK3_1	246	253	PF00069	0.737
MOD_GSK3_1	300	307	PF00069	0.810
MOD_GSK3_1	344	351	PF00069	0.735
MOD_GSK3_1	50	57	PF00069	0.731
MOD_GSK3_1	6	13	PF00069	0.680
MOD_PIKK_1	137	143	PF00454	0.746
MOD_PIKK_1	235	241	PF00454	0.731
MOD_PIKK_1	333	339	PF00454	0.736
MOD_PIKK_1	39	45	PF00454	0.731
MOD_PK_1	212	218	PF00069	0.694
MOD_PKB_1	135	143	PF00069	0.745
MOD_PKB_1	233	241	PF00069	0.732
MOD_PKB_1	331	339	PF00069	0.736
MOD_PKB_1	37	45	PF00069	0.731
MOD_ProDKin_1	130	136	PF00069	0.700
MOD_ProDKin_1	228	234	PF00069	0.718
MOD_ProDKin_1	32	38	PF00069	0.713
MOD_ProDKin_1	326	332	PF00069	0.719
MOD_SUMO_rev_2	145	154	PF00179	0.740
TRG_ENDOCYTIC_2	167	170	PF00928	0.695
TRG_ENDOCYTIC_2	265	268	PF00928	0.700
TRG_ENDOCYTIC_2	363	366	PF00928	0.596
TRG_ENDOCYTIC_2	69	72	PF00928	0.689
TRG_ER_diArg_1	134	137	PF00400	0.730
TRG_ER_diLys_1	396	399	PF00400	0.607
TRG_NLS_Bipartite_1	120	140	PF00514	0.715
TRG_NLS_MonoExtC_3	134	139	PF00514	0.736
TRG_NLS_MonoExtN_4	134	140	PF00514	0.737

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4H3G3	Leishmania braziliensis	96%	100%