SLACS like gene retrotransposon element

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

SLACS like gene retrotransposon element (fragment)

Species:

Leishmania braziliensis

UniProt:

A4H3G9_LEIBR

TriTrypDb:

LbrM.02.0760 , LBRM2903_160011000

Length:

438

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H3G9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H3G9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	137	139	PF00675	0.561
CLV_NRD_NRD_1	390	392	PF00675	0.666
CLV_NRD_NRD_1	411	413	PF00675	0.632
CLV_NRD_NRD_1	419	421	PF00675	0.571
CLV_NRD_NRD_1	428	430	PF00675	0.721
CLV_NRD_NRD_1	55	57	PF00675	0.756
CLV_PCSK_KEX2_1	137	139	PF00082	0.561
CLV_PCSK_KEX2_1	3	5	PF00082	0.805
CLV_PCSK_KEX2_1	411	413	PF00082	0.632
CLV_PCSK_KEX2_1	419	421	PF00082	0.571
CLV_PCSK_KEX2_1	428	430	PF00082	0.721
CLV_PCSK_KEX2_1	55	57	PF00082	0.756
CLV_PCSK_PC1ET2_1	3	5	PF00082	0.805
CLV_PCSK_SKI1_1	137	141	PF00082	0.592
DEG_Nend_Nbox_1	1	3	PF02207	0.602
DOC_MAPK_DCC_7	234	243	PF00069	0.640
DOC_MAPK_MEF2A_6	234	243	PF00069	0.640
DOC_PP2B_LxvP_1	116	119	PF13499	0.657
DOC_USP7_MATH_1	11	15	PF00917	0.722
DOC_USP7_MATH_1	32	36	PF00917	0.709
DOC_USP7_MATH_1	71	75	PF00917	0.606
DOC_WW_Pin1_4	118	123	PF00397	0.620
DOC_WW_Pin1_4	264	269	PF00397	0.391
DOC_WW_Pin1_4	423	428	PF00397	0.666
DOC_WW_Pin1_4	50	55	PF00397	0.724
DOC_WW_Pin1_4	57	62	PF00397	0.633
LIG_14-3-3_CanoR_1	351	355	PF00244	0.712
LIG_AP2alpha_2	347	349	PF02296	0.776
LIG_APCC_ABBA_1	215	220	PF00400	0.564
LIG_BRCT_BRCA1_1	185	189	PF00533	0.649
LIG_FHA_1	327	333	PF00498	0.897
LIG_FHA_1	420	426	PF00498	0.638
LIG_FHA_1	74	80	PF00498	0.583
LIG_FHA_2	104	110	PF00498	0.664
LIG_FHA_2	128	134	PF00498	0.643
LIG_FHA_2	18	24	PF00498	0.662
LIG_FHA_2	289	295	PF00498	0.720
LIG_IBAR_NPY_1	255	257	PF08397	0.620
LIG_LIR_Apic_2	167	173	PF02991	0.674
LIG_LIR_Apic_2	7	11	PF02991	0.765
LIG_LIR_Nem_3	186	192	PF02991	0.668
LIG_LIR_Nem_3	283	288	PF02991	0.658
LIG_PTAP_UEV_1	336	341	PF05743	0.890
LIG_SH2_GRB2like	31	34	PF00017	0.706
LIG_SH2_NCK_1	170	174	PF00017	0.696
LIG_SH2_STAT5	149	152	PF00017	0.673
LIG_SH2_STAT5	18	21	PF00017	0.632
LIG_SH2_STAT5	274	277	PF00017	0.612
LIG_SH3_2	331	336	PF14604	0.905
LIG_SH3_2	341	346	PF14604	0.642
LIG_SH3_2	424	429	PF14604	0.673
LIG_SH3_3	116	122	PF00018	0.635
LIG_SH3_3	223	229	PF00018	0.582
LIG_SH3_3	233	239	PF00018	0.553
LIG_SH3_3	242	248	PF00018	0.330
LIG_SH3_3	294	300	PF00018	0.716
LIG_SH3_3	311	317	PF00018	0.466
LIG_SH3_3	328	334	PF00018	0.601
LIG_SH3_3	337	343	PF00018	0.723
LIG_SH3_3	371	377	PF00018	0.797
LIG_SH3_3	421	427	PF00018	0.629
LIG_SH3_3	83	89	PF00018	0.606
LIG_TRAF2_1	361	364	PF00917	0.837
MOD_CDC14_SPxK_1	426	429	PF00782	0.634
MOD_CDK_SPK_2	264	269	PF00069	0.391
MOD_CDK_SPK_2	423	428	PF00069	0.629
MOD_CDK_SPK_2	50	55	PF00069	0.724
MOD_CDK_SPxK_1	423	429	PF00069	0.673
MOD_CDK_SPxK_1	50	56	PF00069	0.731
MOD_CK1_1	211	217	PF00069	0.615
MOD_CK1_1	50	56	PF00069	0.731
MOD_CK2_1	103	109	PF00069	0.675
MOD_Cter_Amidation	409	412	PF01082	0.623
MOD_GlcNHglycan	192	195	PF01048	0.695
MOD_GlcNHglycan	210	213	PF01048	0.294
MOD_GlcNHglycan	49	52	PF01048	0.736
MOD_GSK3_1	202	209	PF00069	0.692
MOD_GSK3_1	246	253	PF00069	0.656
MOD_GSK3_1	288	295	PF00069	0.711
MOD_GSK3_1	304	311	PF00069	0.363
MOD_GSK3_1	376	383	PF00069	0.888
MOD_GSK3_1	419	426	PF00069	0.656
MOD_GSK3_1	65	72	PF00069	0.654
MOD_GSK3_1	99	106	PF00069	0.648
MOD_N-GLC_1	32	37	PF02516	0.711
MOD_NEK2_1	140	145	PF00069	0.614
MOD_NEK2_1	308	313	PF00069	0.654
MOD_NEK2_1	99	104	PF00069	0.677
MOD_NEK2_2	288	293	PF00069	0.709
MOD_PIKK_1	250	256	PF00454	0.664
MOD_PIKK_1	381	387	PF00454	0.857
MOD_PKA_1	419	425	PF00069	0.635
MOD_PKA_2	332	338	PF00069	0.903
MOD_PKA_2	350	356	PF00069	0.417
MOD_PKA_2	413	419	PF00069	0.644
MOD_PKA_2	99	105	PF00069	0.682
MOD_Plk_1	91	97	PF00069	0.651
MOD_Plk_2-3	301	307	PF00069	0.675
MOD_Plk_4	12	18	PF00069	0.688
MOD_Plk_4	211	217	PF00069	0.612
MOD_Plk_4	304	310	PF00069	0.641
MOD_Plk_4	91	97	PF00069	0.651
MOD_ProDKin_1	118	124	PF00069	0.623
MOD_ProDKin_1	264	270	PF00069	0.388
MOD_ProDKin_1	423	429	PF00069	0.666
MOD_ProDKin_1	50	56	PF00069	0.731
MOD_ProDKin_1	57	63	PF00069	0.624
TRG_ER_diArg_1	136	138	PF00400	0.557
TRG_ER_diArg_1	411	414	PF00400	0.682
TRG_ER_diArg_1	418	420	PF00400	0.685
TRG_ER_diArg_1	427	429	PF00400	0.728
TRG_ER_diArg_1	54	56	PF00400	0.738

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4H3G2	Leishmania braziliensis	96%	100%