SLACS like gene retrotransposon element

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

SLACS like gene retrotransposon element

Species:

Leishmania braziliensis

UniProt:

A4H3G5_LEIBR

TriTrypDb:

LbrM.02.0720 , LBRM2903_160010900

Length:

251

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H3G5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H3G5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	168	170	PF00675	0.527
CLV_NRD_NRD_1	246	248	PF00675	0.350
CLV_PCSK_KEX2_1	109	111	PF00082	0.546
CLV_PCSK_KEX2_1	168	170	PF00082	0.438
CLV_PCSK_KEX2_1	246	248	PF00082	0.393
CLV_PCSK_PC1ET2_1	109	111	PF00082	0.541
CLV_PCSK_PC1ET2_1	168	170	PF00082	0.438
CLV_PCSK_SKI1_1	17	21	PF00082	0.432
CLV_PCSK_SKI1_1	215	219	PF00082	0.520
CLV_PCSK_SKI1_1	246	250	PF00082	0.420
CLV_PCSK_SKI1_1	59	63	PF00082	0.379
DEG_APCC_DBOX_1	58	66	PF00400	0.368
DEG_Nend_UBRbox_3	1	2	PF02207	0.547
DEG_SPOP_SBC_1	121	125	PF00917	0.518
DOC_CYCLIN_RxL_1	11	22	PF00134	0.429
DOC_CYCLIN_yCln2_LP_2	40	46	PF00134	0.517
DOC_MAPK_gen_1	57	64	PF00069	0.368
DOC_MAPK_MEF2A_6	38	47	PF00069	0.596
DOC_MAPK_MEF2A_6	57	64	PF00069	0.239
DOC_MAPK_NFAT4_5	57	65	PF00069	0.364
DOC_PP1_RVXF_1	107	114	PF00149	0.468
DOC_USP7_MATH_1	119	123	PF00917	0.504
LIG_14-3-3_CanoR_1	120	129	PF00244	0.515
LIG_14-3-3_CanoR_1	151	160	PF00244	0.452
LIG_14-3-3_CterR_2	246	251	PF00244	0.529
LIG_deltaCOP1_diTrp_1	105	113	PF00928	0.464
LIG_FHA_1	140	146	PF00498	0.429
LIG_FHA_1	188	194	PF00498	0.444
LIG_FHA_1	3	9	PF00498	0.484
LIG_FHA_1	35	41	PF00498	0.505
LIG_FHA_2	122	128	PF00498	0.529
LIG_FHA_2	214	220	PF00498	0.472
LIG_FXI_DFP_1	47	51	PF00024	0.354
LIG_LIR_Gen_1	196	205	PF02991	0.449
LIG_LIR_Gen_1	216	225	PF02991	0.360
LIG_LIR_Gen_1	49	60	PF02991	0.458
LIG_LIR_Nem_3	180	185	PF02991	0.371
LIG_LIR_Nem_3	196	201	PF02991	0.339
LIG_LIR_Nem_3	216	221	PF02991	0.366
LIG_LIR_Nem_3	49	55	PF02991	0.363
LIG_PCNA_yPIPBox_3	57	65	PF02747	0.457
LIG_SH2_STAT5	235	238	PF00017	0.566
LIG_SH3_3	113	119	PF00018	0.482
LIG_SH3_3	61	67	PF00018	0.468
LIG_SH3_3	83	89	PF00018	0.514
LIG_SUMO_SIM_par_1	183	190	PF11976	0.452
LIG_TRAF2_1	217	220	PF00917	0.453
LIG_ULM_U2AF65_1	167	172	PF00076	0.506
MOD_CK1_1	122	128	PF00069	0.529
MOD_CK1_1	186	192	PF00069	0.449
MOD_CK1_1	213	219	PF00069	0.475
MOD_CK1_1	223	229	PF00069	0.435
MOD_CK2_1	121	127	PF00069	0.522
MOD_CK2_1	213	219	PF00069	0.475
MOD_CK2_1	99	105	PF00069	0.459
MOD_CMANNOS	171	174	PF00535	0.497
MOD_GlcNHglycan	101	104	PF01048	0.457
MOD_GlcNHglycan	124	127	PF01048	0.532
MOD_GlcNHglycan	153	156	PF01048	0.582
MOD_GSK3_1	183	190	PF00069	0.545
MOD_N-GLC_2	83	85	PF02516	0.489
MOD_NEK2_1	129	134	PF00069	0.457
MOD_NEK2_1	187	192	PF00069	0.449
MOD_PKA_2	119	125	PF00069	0.419
MOD_Plk_1	129	135	PF00069	0.458
MOD_Plk_4	15	21	PF00069	0.423
TRG_AP2beta_CARGO_1	49	59	PF09066	0.454
TRG_DiLeu_BaLyEn_6	244	249	PF01217	0.377
TRG_DiLeu_BaLyEn_6	56	61	PF01217	0.369
TRG_ER_diArg_1	246	248	PF00400	0.379
TRG_ER_diArg_1	56	59	PF00400	0.450
TRG_NLS_MonoCore_2	166	171	PF00514	0.508
TRG_NLS_MonoExtC_3	167	173	PF00514	0.512
TRG_NLS_MonoExtN_4	167	172	PF00514	0.506
TRG_Pf-PMV_PEXEL_1	227	231	PF00026	0.435
TRG_Pf-PMV_PEXEL_1	38	42	PF00026	0.410
TRG_Pf-PMV_PEXEL_1	63	68	PF00026	0.376

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A1X0NL69	Trypanosomatidae	31%	87%
A4HEK6	Leishmania braziliensis	95%	100%