HTH_Tnp_Tc3_2 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania braziliensis

UniProt:

A4H3G1_LEIBR

TriTrypDb:

LbrM.02.0680 , LBRM2903_020012700 , LBRM2903_020012800

Length:

514

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A4H3G1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H3G1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	179	183	PF00656	0.703
CLV_C14_Caspase3-7	288	292	PF00656	0.705
CLV_C14_Caspase3-7	390	394	PF00656	0.547
CLV_C14_Caspase3-7	499	503	PF00656	0.685
CLV_C14_Caspase3-7	70	74	PF00656	0.708
CLV_C14_Caspase3-7	86	90	PF00656	0.534
CLV_NRD_NRD_1	118	120	PF00675	0.710
CLV_NRD_NRD_1	163	165	PF00675	0.624
CLV_NRD_NRD_1	172	174	PF00675	0.567
CLV_NRD_NRD_1	227	229	PF00675	0.709
CLV_NRD_NRD_1	272	274	PF00675	0.762
CLV_NRD_NRD_1	281	283	PF00675	0.654
CLV_NRD_NRD_1	397	399	PF00675	0.542
CLV_NRD_NRD_1	54	56	PF00675	0.623
CLV_NRD_NRD_1	63	65	PF00675	0.561
CLV_PCSK_FUR_1	161	165	PF00082	0.616
CLV_PCSK_FUR_1	170	174	PF00082	0.571
CLV_PCSK_FUR_1	270	274	PF00082	0.625
CLV_PCSK_FUR_1	279	283	PF00082	0.583
CLV_PCSK_FUR_1	52	56	PF00082	0.614
CLV_PCSK_FUR_1	61	65	PF00082	0.566
CLV_PCSK_KEX2_1	117	119	PF00082	0.718
CLV_PCSK_KEX2_1	163	165	PF00082	0.624
CLV_PCSK_KEX2_1	172	174	PF00082	0.567
CLV_PCSK_KEX2_1	226	228	PF00082	0.717
CLV_PCSK_KEX2_1	272	274	PF00082	0.631
CLV_PCSK_KEX2_1	281	283	PF00082	0.582
CLV_PCSK_KEX2_1	54	56	PF00082	0.623
CLV_PCSK_KEX2_1	63	65	PF00082	0.561
CLV_PCSK_PC7_1	114	120	PF00082	0.721
CLV_PCSK_PC7_1	159	165	PF00082	0.612
CLV_PCSK_PC7_1	223	229	PF00082	0.718
CLV_PCSK_PC7_1	268	274	PF00082	0.618
CLV_PCSK_PC7_1	50	56	PF00082	0.606
CLV_PCSK_SKI1_1	510	514	PF00082	0.729
DEG_Nend_UBRbox_2	1	3	PF02207	0.742
DEG_SPOP_SBC_1	504	508	PF00917	0.687
DOC_CKS1_1	302	307	PF01111	0.683
DOC_CKS1_1	329	334	PF01111	0.666
DOC_CKS1_1	356	361	PF01111	0.652
DOC_CKS1_1	411	416	PF01111	0.633
DOC_CKS1_1	438	443	PF01111	0.659
DOC_CKS1_1	465	470	PF01111	0.669
DOC_MAPK_gen_1	159	168	PF00069	0.614
DOC_MAPK_gen_1	268	277	PF00069	0.620
DOC_MAPK_gen_1	50	59	PF00069	0.609
DOC_SPAK_OSR1_1	157	161	PF12202	0.604
DOC_SPAK_OSR1_1	266	270	PF12202	0.604
DOC_SPAK_OSR1_1	48	52	PF12202	0.594
DOC_USP7_MATH_1	311	315	PF00917	0.653
DOC_USP7_MATH_1	336	340	PF00917	0.630
DOC_USP7_MATH_1	365	369	PF00917	0.624
DOC_USP7_MATH_1	420	424	PF00917	0.635
DOC_USP7_MATH_1	445	449	PF00917	0.636
DOC_USP7_MATH_1	474	478	PF00917	0.658
DOC_WW_Pin1_4	301	306	PF00397	0.695
DOC_WW_Pin1_4	328	333	PF00397	0.679
DOC_WW_Pin1_4	355	360	PF00397	0.670
DOC_WW_Pin1_4	410	415	PF00397	0.648
DOC_WW_Pin1_4	437	442	PF00397	0.673
DOC_WW_Pin1_4	464	469	PF00397	0.685
DOC_WW_Pin1_4	491	496	PF00397	0.697
DOC_WW_Pin1_4	6	11	PF00397	0.710
LIG_14-3-3_CanoR_1	148	158	PF00244	0.606
LIG_14-3-3_CanoR_1	257	267	PF00244	0.650
LIG_14-3-3_CanoR_1	39	49	PF00244	0.595
LIG_14-3-3_CanoR_1	505	512	PF00244	0.708
LIG_Actin_WH2_2	200	216	PF00022	0.708
LIG_Actin_WH2_2	91	107	PF00022	0.704
LIG_EH_1	384	388	PF12763	0.556
LIG_FHA_1	93	99	PF00498	0.698
LIG_FHA_2	193	199	PF00498	0.712
LIG_FHA_2	388	394	PF00498	0.548
LIG_FHA_2	497	503	PF00498	0.685
LIG_FHA_2	84	90	PF00498	0.707
LIG_LIR_Nem_3	169	174	PF02991	0.685
LIG_LIR_Nem_3	278	283	PF02991	0.678
LIG_LIR_Nem_3	382	387	PF02991	0.565
LIG_LIR_Nem_3	491	496	PF02991	0.697
LIG_LIR_Nem_3	60	65	PF02991	0.691
LIG_SH2_NCK_1	146	150	PF00017	0.632
LIG_SH2_NCK_1	255	259	PF00017	0.611
LIG_SH2_NCK_1	37	41	PF00017	0.619
LIG_SH3_1	100	106	PF00018	0.707
LIG_SH3_3	104	110	PF00018	0.621
LIG_SH3_3	204	210	PF00018	0.707
LIG_SH3_3	213	219	PF00018	0.613
LIG_SH3_3	95	101	PF00018	0.699
MOD_CDK_SPxxK_3	6	13	PF00069	0.711
MOD_CK1_1	108	114	PF00069	0.729
MOD_CK1_1	217	223	PF00069	0.722
MOD_CK1_1	491	497	PF00069	0.697
MOD_CK2_1	149	155	PF00069	0.607
MOD_CK2_1	258	264	PF00069	0.593
MOD_CK2_1	40	46	PF00069	0.596
MOD_Cter_Amidation	115	118	PF01082	0.724
MOD_Cter_Amidation	224	227	PF01082	0.719
MOD_GlcNHglycan	107	110	PF01048	0.721
MOD_GlcNHglycan	151	154	PF01048	0.633
MOD_GlcNHglycan	204	207	PF01048	0.712
MOD_GlcNHglycan	216	219	PF01048	0.582
MOD_GlcNHglycan	260	263	PF01048	0.583
MOD_GlcNHglycan	42	45	PF01048	0.585
MOD_GlcNHglycan	95	98	PF01048	0.751
MOD_GSK3_1	129	136	PF00069	0.695
MOD_GSK3_1	178	185	PF00069	0.760
MOD_GSK3_1	192	199	PF00069	0.560
MOD_GSK3_1	2	9	PF00069	0.721
MOD_GSK3_1	20	27	PF00069	0.697
MOD_GSK3_1	238	245	PF00069	0.740
MOD_GSK3_1	287	294	PF00069	0.704
MOD_GSK3_1	69	76	PF00069	0.709
MOD_NEK2_1	387	392	PF00069	0.557
MOD_NEK2_1	496	501	PF00069	0.681
MOD_PKA_1	118	124	PF00069	0.707
MOD_PKA_1	227	233	PF00069	0.708
MOD_PKA_2	118	124	PF00069	0.707
MOD_PKA_2	133	139	PF00069	0.512
MOD_PKA_2	227	233	PF00069	0.708
MOD_PKA_2	24	30	PF00069	0.671
MOD_PKA_2	242	248	PF00069	0.498
MOD_PKA_2	504	510	PF00069	0.697
MOD_Plk_4	311	317	PF00069	0.654
MOD_Plk_4	338	344	PF00069	0.634
MOD_Plk_4	365	371	PF00069	0.622
MOD_Plk_4	420	426	PF00069	0.631
MOD_Plk_4	447	453	PF00069	0.642
MOD_Plk_4	474	480	PF00069	0.657
MOD_ProDKin_1	301	307	PF00069	0.688
MOD_ProDKin_1	328	334	PF00069	0.674
MOD_ProDKin_1	355	361	PF00069	0.660
MOD_ProDKin_1	410	416	PF00069	0.642
MOD_ProDKin_1	437	443	PF00069	0.665
MOD_ProDKin_1	464	470	PF00069	0.675
MOD_ProDKin_1	491	497	PF00069	0.697
MOD_ProDKin_1	6	12	PF00069	0.710
TRG_ER_diArg_1	117	119	PF00400	0.718
TRG_ER_diArg_1	158	161	PF00400	0.602
TRG_ER_diArg_1	171	173	PF00400	0.519
TRG_ER_diArg_1	226	228	PF00400	0.717
TRG_ER_diArg_1	267	270	PF00400	0.604
TRG_ER_diArg_1	280	282	PF00400	0.542
TRG_ER_diArg_1	49	52	PF00400	0.593
TRG_ER_diArg_1	62	64	PF00400	0.527
TRG_NLS_Bipartite_1	117	132	PF00514	0.712
TRG_NLS_Bipartite_1	226	241	PF00514	0.710
TRG_NLS_MonoExtC_3	127	133	PF00514	0.709
TRG_NLS_MonoExtC_3	18	24	PF00514	0.714
TRG_NLS_MonoExtC_3	236	242	PF00514	0.704
TRG_NLS_MonoExtN_4	17	23	PF00514	0.726
TRG_Pf-PMV_PEXEL_1	164	169	PF00026	0.734
TRG_Pf-PMV_PEXEL_1	273	278	PF00026	0.631
TRG_Pf-PMV_PEXEL_1	55	60	PF00026	0.623

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HG38	Leishmania braziliensis	91%	100%