Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

A4H3C3_LEIBR

TriTrypDb:

LbrM.02.0300 , LBRM2903_020008100

Length:


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

A4H3C3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H3C3


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	35	37	PF00675	0.557
CLV_PCSK_KEX2_1	35	37	PF00082	0.557
DEG_Nend_Nbox_1	1	3	PF02207	0.678
DOC_WW_Pin1_4	58	63	PF00397	0.487
LIG_14-3-3_CanoR_1	47	51	PF00244	0.587
LIG_BRCT_BRCA1_1	9	13	PF00533	0.440
LIG_FHA_1	59	65	PF00498	0.568
LIG_LIR_Gen_1	22	30	PF02991	0.566
LIG_LIR_Gen_1	38	46	PF02991	0.542
LIG_LIR_Nem_3	22	28	PF02991	0.564
LIG_LIR_Nem_3	38	42	PF02991	0.549
LIG_Pex14_2	42	46	PF04695	0.534
LIG_Pex14_2	5	9	PF04695	0.525
LIG_SH2_STAP1	25	29	PF00017	0.564
MOD_DYRK1A_RPxSP_1	58	62	PF00069	0.484
MOD_GSK3_1	56	63	PF00069	0.531
MOD_NEK2_1	24	29	PF00069	0.563
MOD_PKA_2	46	52	PF00069	0.592
MOD_Plk_4	24	30	PF00069	0.652
MOD_Plk_4	60	66	PF00069	0.497
MOD_ProDKin_1	58	64	PF00069	0.490
TRG_ENDOCYTIC_2	25	28	PF00928	0.567


Protein	Taxonomy	Sequence identity	Coverage
A0A1X0NLH5	Trypanosomatidae	77%	69%
A0A3S5H4Z3	Leishmania donovani	84%	100%
A4HRM4	Leishmania infantum	84%	100%
C9ZIZ2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	70%	67%
E9ACA2	Leishmania major	84%	100%
E9AJJ0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%