HSP70-like protein

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

HSP70-like protein

Gene product:

HSP70-like protein

Species:

Leishmania braziliensis

UniProt:

A4H397_LEIBR

TriTrypDb:

LbrM.01.0790 , LBRM2903_010011900

Length:

1118

Annotations

LeishMANIAdb annotations

Appears to be a secreted chaperone, related to mammalian HYOU1 proteins. Probably ER-localized as in other eukaryotes

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 3, no: 6
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0043226	organelle	2	10
GO:0110165	cellular anatomical entity	1	10
GO:0005634	nucleus	5	1
GO:0005737	cytoplasm	2	1
GO:0005788	endoplasmic reticulum lumen	5	1
GO:0016020	membrane	2	2
GO:0031974	membrane-enclosed lumen	2	1
GO:0032991	protein-containing complex	1	1
GO:0034663	endoplasmic reticulum chaperone complex	3	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0140534	endoplasmic reticulum protein-containing complex	2	1

Expansion

Sequence features

A4H397

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A4H397

Function

Biological processes
Term	Name	Level	Count
GO:0006457	protein folding	2	1
GO:0006458	'de novo' protein folding	3	1
GO:0006508	proteolysis	4	1
GO:0006511	ubiquitin-dependent protein catabolic process	7	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0006950	response to stress	2	1
GO:0006986	response to unfolded protein	4	1
GO:0007165	signal transduction	2	1
GO:0008152	metabolic process	1	1
GO:0009056	catabolic process	2	1
GO:0009057	macromolecule catabolic process	4	1
GO:0009987	cellular process	1	1
GO:0010033	response to organic substance	3	1
GO:0010243	response to organonitrogen compound	4	1
GO:0010498	proteasomal protein catabolic process	5	1
GO:0019538	protein metabolic process	3	1
GO:0019941	modification-dependent protein catabolic process	6	1
GO:0030163	protein catabolic process	4	1
GO:0030433	ubiquitin-dependent ERAD pathway	6	1
GO:0030968	endoplasmic reticulum unfolded protein response	3	1
GO:0033554	cellular response to stress	3	1
GO:0034620	cellular response to unfolded protein	5	1
GO:0034976	response to endoplasmic reticulum stress	4	1
GO:0035966	response to topologically incorrect protein	3	1
GO:0035967	cellular response to topologically incorrect protein	4	1
GO:0036503	ERAD pathway	5	1
GO:0042026	protein refolding	3	1
GO:0042221	response to chemical	2	1
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	6	1
GO:0043170	macromolecule metabolic process	3	1
GO:0043632	modification-dependent macromolecule catabolic process	5	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044248	cellular catabolic process	3	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0044265	obsolete cellular macromolecule catabolic process	4	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0050896	response to stimulus	1	1
GO:0051084	'de novo' post-translational protein folding	4	1
GO:0051085	chaperone cofactor-dependent protein refolding	4	1
GO:0051603	proteolysis involved in protein catabolic process	5	1
GO:0051716	cellular response to stimulus	2	1
GO:0061077	chaperone-mediated protein folding	3	1
GO:0065007	biological regulation	1	1
GO:0070887	cellular response to chemical stimulus	3	1
GO:0071310	cellular response to organic substance	4	1
GO:0071704	organic substance metabolic process	2	1
GO:1901564	organonitrogen compound metabolic process	3	1
GO:1901565	organonitrogen compound catabolic process	4	1
GO:1901575	organic substance catabolic process	3	1
GO:1901698	response to nitrogen compound	3	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	10
GO:0005488	binding	1	10
GO:0005524	ATP binding	5	10
GO:0017076	purine nucleotide binding	4	10
GO:0030554	adenyl nucleotide binding	5	10
GO:0032553	ribonucleotide binding	3	10
GO:0032555	purine ribonucleotide binding	4	10
GO:0032559	adenyl ribonucleotide binding	5	10
GO:0035639	purine ribonucleoside triphosphate binding	4	10
GO:0036094	small molecule binding	2	10
GO:0043167	ion binding	2	10
GO:0043168	anion binding	3	10
GO:0044183	protein folding chaperone	1	10
GO:0097159	organic cyclic compound binding	2	10
GO:0097367	carbohydrate derivative binding	2	10
GO:0140657	ATP-dependent activity	1	10
GO:0140662	ATP-dependent protein folding chaperone	2	10
GO:1901265	nucleoside phosphate binding	3	10
GO:1901363	heterocyclic compound binding	2	10
GO:0003824	catalytic activity	1	1
GO:0005515	protein binding	2	1
GO:0016462	pyrophosphatase activity	5	1
GO:0016787	hydrolase activity	2	1
GO:0016817	hydrolase activity, acting on acid anhydrides	3	1
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	1
GO:0016887	ATP hydrolysis activity	7	1
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	1
GO:0031072	heat shock protein binding	3	1
GO:0051082	unfolded protein binding	3	1
GO:0051787	misfolded protein binding	3	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	158	162	PF00656	0.607
CLV_C14_Caspase3-7	340	344	PF00656	0.483
CLV_C14_Caspase3-7	932	936	PF00656	0.450
CLV_MEL_PAP_1	975	981	PF00089	0.643
CLV_NRD_NRD_1	1007	1009	PF00675	0.619
CLV_NRD_NRD_1	1021	1023	PF00675	0.538
CLV_NRD_NRD_1	125	127	PF00675	0.628
CLV_NRD_NRD_1	170	172	PF00675	0.633
CLV_NRD_NRD_1	18	20	PF00675	0.581
CLV_NRD_NRD_1	333	335	PF00675	0.625
CLV_NRD_NRD_1	357	359	PF00675	0.593
CLV_NRD_NRD_1	46	48	PF00675	0.633
CLV_NRD_NRD_1	511	513	PF00675	0.570
CLV_NRD_NRD_1	528	530	PF00675	0.378
CLV_NRD_NRD_1	580	582	PF00675	0.586
CLV_NRD_NRD_1	597	599	PF00675	0.462
CLV_PCSK_FUR_1	1019	1023	PF00082	0.603
CLV_PCSK_KEX2_1	1007	1009	PF00082	0.619
CLV_PCSK_KEX2_1	1021	1023	PF00082	0.538
CLV_PCSK_KEX2_1	170	172	PF00082	0.633
CLV_PCSK_KEX2_1	18	20	PF00082	0.541
CLV_PCSK_KEX2_1	333	335	PF00082	0.585
CLV_PCSK_KEX2_1	45	47	PF00082	0.632
CLV_PCSK_KEX2_1	511	513	PF00082	0.547
CLV_PCSK_KEX2_1	528	530	PF00082	0.379
CLV_PCSK_KEX2_1	580	582	PF00082	0.586
CLV_PCSK_KEX2_1	597	599	PF00082	0.462
CLV_PCSK_PC7_1	14	20	PF00082	0.549
CLV_PCSK_PC7_1	507	513	PF00082	0.507
CLV_PCSK_SKI1_1	1068	1072	PF00082	0.551
CLV_PCSK_SKI1_1	1108	1112	PF00082	0.575
CLV_PCSK_SKI1_1	279	283	PF00082	0.641
CLV_PCSK_SKI1_1	315	319	PF00082	0.528
CLV_PCSK_SKI1_1	401	405	PF00082	0.535
CLV_PCSK_SKI1_1	511	515	PF00082	0.470
CLV_PCSK_SKI1_1	546	550	PF00082	0.492
CLV_PCSK_SKI1_1	580	584	PF00082	0.462
CLV_PCSK_SKI1_1	605	609	PF00082	0.507
CLV_PCSK_SKI1_1	738	742	PF00082	0.501
DEG_APCC_DBOX_1	510	518	PF00400	0.243
DEG_SPOP_SBC_1	109	113	PF00917	0.519
DEG_SPOP_SBC_1	143	147	PF00917	0.482
DEG_SPOP_SBC_1	2	6	PF00917	0.266
DEG_SPOP_SBC_1	419	423	PF00917	0.308
DEG_SPOP_SBC_1	953	957	PF00917	0.500
DOC_ANK_TNKS_1	633	640	PF00023	0.292
DOC_CKS1_1	137	142	PF01111	0.378
DOC_CYCLIN_yClb5_NLxxxL_5	473	480	PF00134	0.191
DOC_CYCLIN_yCln2_LP_2	390	396	PF00134	0.307
DOC_MAPK_DCC_7	126	134	PF00069	0.496
DOC_MAPK_DCC_7	23	32	PF00069	0.391
DOC_MAPK_gen_1	126	134	PF00069	0.413
DOC_MAPK_gen_1	439	448	PF00069	0.262
DOC_MAPK_HePTP_8	276	288	PF00069	0.403
DOC_MAPK_MEF2A_6	126	134	PF00069	0.482
DOC_MAPK_MEF2A_6	23	32	PF00069	0.452
DOC_MAPK_MEF2A_6	279	288	PF00069	0.451
DOC_MAPK_MEF2A_6	386	394	PF00069	0.246
DOC_MAPK_MEF2A_6	971	979	PF00069	0.402
DOC_MAPK_RevD_3	33	47	PF00069	0.228
DOC_PP2B_LxvP_1	390	393	PF13499	0.267
DOC_PP4_FxxP_1	137	140	PF00568	0.494
DOC_SPAK_OSR1_1	634	638	PF12202	0.267
DOC_USP7_MATH_1	1048	1052	PF00917	0.503
DOC_USP7_MATH_1	1066	1070	PF00917	0.434
DOC_USP7_MATH_1	2	6	PF00917	0.278
DOC_USP7_MATH_1	227	231	PF00917	0.552
DOC_USP7_MATH_1	311	315	PF00917	0.449
DOC_USP7_MATH_1	361	365	PF00917	0.366
DOC_USP7_MATH_1	469	473	PF00917	0.284
DOC_USP7_MATH_1	564	568	PF00917	0.335
DOC_USP7_MATH_1	743	747	PF00917	0.350
DOC_USP7_MATH_1	758	762	PF00917	0.288
DOC_USP7_MATH_1	844	848	PF00917	0.378
DOC_USP7_MATH_1	850	854	PF00917	0.385
DOC_USP7_MATH_1	959	963	PF00917	0.582
DOC_WW_Pin1_4	1052	1057	PF00397	0.524
DOC_WW_Pin1_4	125	130	PF00397	0.457
DOC_WW_Pin1_4	136	141	PF00397	0.475
DOC_WW_Pin1_4	153	158	PF00397	0.463
DOC_WW_Pin1_4	754	759	PF00397	0.403
DOC_WW_Pin1_4	939	944	PF00397	0.555
DOC_WW_Pin1_4	954	959	PF00397	0.599
DOC_WW_Pin1_4	970	975	PF00397	0.398
LIG_14-3-3_CanoR_1	1019	1029	PF00244	0.371
LIG_14-3-3_CanoR_1	1079	1088	PF00244	0.341
LIG_14-3-3_CanoR_1	170	177	PF00244	0.501
LIG_14-3-3_CanoR_1	273	277	PF00244	0.517
LIG_14-3-3_CanoR_1	301	309	PF00244	0.382
LIG_14-3-3_CanoR_1	31	36	PF00244	0.272
LIG_14-3-3_CanoR_1	417	427	PF00244	0.301
LIG_14-3-3_CanoR_1	45	54	PF00244	0.424
LIG_14-3-3_CanoR_1	580	585	PF00244	0.391
LIG_14-3-3_CanoR_1	662	672	PF00244	0.293
LIG_14-3-3_CanoR_1	714	720	PF00244	0.323
LIG_14-3-3_CanoR_1	796	801	PF00244	0.354
LIG_14-3-3_CanoR_1	992	996	PF00244	0.517
LIG_Actin_WH2_2	1005	1023	PF00022	0.435
LIG_Actin_WH2_2	1097	1114	PF00022	0.387
LIG_Actin_WH2_2	965	980	PF00022	0.456
LIG_BRCT_BRCA1_1	48	52	PF00533	0.504
LIG_BRCT_BRCA1_1	781	785	PF00533	0.351
LIG_Clathr_ClatBox_1	73	77	PF01394	0.473
LIG_CtBP_PxDLS_1	683	687	PF00389	0.314
LIG_CtBP_PxDLS_1	974	978	PF00389	0.333
LIG_deltaCOP1_diTrp_1	1083	1088	PF00928	0.275
LIG_deltaCOP1_diTrp_1	601	608	PF00928	0.307
LIG_DLG_GKlike_1	31	38	PF00625	0.205
LIG_FHA_1	111	117	PF00498	0.554
LIG_FHA_1	197	203	PF00498	0.408
LIG_FHA_1	210	216	PF00498	0.363
LIG_FHA_1	22	28	PF00498	0.675
LIG_FHA_1	323	329	PF00498	0.419
LIG_FHA_1	373	379	PF00498	0.395
LIG_FHA_1	380	386	PF00498	0.311
LIG_FHA_1	389	395	PF00498	0.269
LIG_FHA_1	46	52	PF00498	0.545
LIG_FHA_1	620	626	PF00498	0.313
LIG_FHA_1	672	678	PF00498	0.383
LIG_FHA_1	69	75	PF00498	0.515
LIG_FHA_1	702	708	PF00498	0.311
LIG_FHA_1	742	748	PF00498	0.404
LIG_FHA_1	795	801	PF00498	0.364
LIG_FHA_2	1093	1099	PF00498	0.273
LIG_FHA_2	153	159	PF00498	0.431
LIG_FHA_2	183	189	PF00498	0.484
LIG_FHA_2	217	223	PF00498	0.489
LIG_FHA_2	67	73	PF00498	0.468
LIG_FHA_2	881	887	PF00498	0.478
LIG_FHA_2	903	909	PF00498	0.536
LIG_FHA_2	930	936	PF00498	0.478
LIG_LIR_Apic_2	601	606	PF02991	0.307
LIG_LIR_Gen_1	238	247	PF02991	0.444
LIG_LIR_Gen_1	462	471	PF02991	0.243
LIG_LIR_Gen_1	705	716	PF02991	0.350
LIG_LIR_Nem_3	238	242	PF02991	0.440
LIG_LIR_Nem_3	462	466	PF02991	0.388
LIG_LIR_Nem_3	633	638	PF02991	0.292
LIG_LIR_Nem_3	705	711	PF02991	0.289
LIG_LYPXL_SIV_4	430	438	PF13949	0.332
LIG_Pex14_1	1084	1088	PF04695	0.385
LIG_Pex14_1	504	508	PF04695	0.332
LIG_PTB_Apo_2	233	240	PF02174	0.363
LIG_RPA_C_Fungi	42	54	PF08784	0.469
LIG_RPA_C_Fungi	712	724	PF08784	0.395
LIG_SH2_CRK	387	391	PF00017	0.403
LIG_SH2_GRB2like	508	511	PF00017	0.205
LIG_SH2_NCK_1	431	435	PF00017	0.205
LIG_SH2_NCK_1	708	712	PF00017	0.273
LIG_SH2_PTP2	445	448	PF00017	0.403
LIG_SH2_SRC	776	779	PF00017	0.557
LIG_SH2_STAP1	211	215	PF00017	0.481
LIG_SH2_STAP1	237	241	PF00017	0.617
LIG_SH2_STAP1	331	335	PF00017	0.409
LIG_SH2_STAP1	461	465	PF00017	0.475
LIG_SH2_STAT5	136	139	PF00017	0.642
LIG_SH2_STAT5	211	214	PF00017	0.553
LIG_SH2_STAT5	285	288	PF00017	0.679
LIG_SH2_STAT5	445	448	PF00017	0.429
LIG_SH2_STAT5	508	511	PF00017	0.373
LIG_SH2_STAT5	794	797	PF00017	0.438
LIG_SH2_STAT5	856	859	PF00017	0.422
LIG_SH3_3	1051	1057	PF00018	0.524
LIG_SH3_3	192	198	PF00018	0.539
LIG_SH3_3	281	287	PF00018	0.558
LIG_SH3_3	375	381	PF00018	0.553
LIG_SH3_3	736	742	PF00018	0.455
LIG_SH3_3	746	752	PF00018	0.564
LIG_SH3_3	940	946	PF00018	0.572
LIG_SUMO_SIM_anti_2	115	120	PF11976	0.510
LIG_SUMO_SIM_anti_2	34	39	PF11976	0.313
LIG_SUMO_SIM_par_1	36	41	PF11976	0.349
LIG_SUMO_SIM_par_1	64	72	PF11976	0.599
LIG_SUMO_SIM_par_1	674	681	PF11976	0.406
LIG_SUMO_SIM_par_1	760	768	PF11976	0.483
LIG_TRAF2_1	1096	1099	PF00917	0.490
LIG_TRAF2_1	162	165	PF00917	0.541
LIG_TRAF2_1	320	323	PF00917	0.359
LIG_TRAF2_1	904	907	PF00917	0.561
LIG_TYR_ITIM	385	390	PF00017	0.480
LIG_TYR_ITIM	443	448	PF00017	0.394
LIG_UBA3_1	1032	1037	PF00899	0.321
LIG_UBA3_1	733	738	PF00899	0.290
LIG_WRC_WIRS_1	460	465	PF05994	0.272
MOD_CK1_1	112	118	PF00069	0.774
MOD_CK1_1	304	310	PF00069	0.567
MOD_CK1_1	379	385	PF00069	0.408
MOD_CK1_1	4	10	PF00069	0.359
MOD_CK1_1	41	47	PF00069	0.607
MOD_CK1_1	715	721	PF00069	0.529
MOD_CK1_1	779	785	PF00069	0.649
MOD_CK1_1	899	905	PF00069	0.625
MOD_CK1_1	952	958	PF00069	0.670
MOD_CK1_1	981	987	PF00069	0.611
MOD_CK2_1	1092	1098	PF00069	0.314
MOD_CK2_1	159	165	PF00069	0.541
MOD_CK2_1	182	188	PF00069	0.624
MOD_CK2_1	216	222	PF00069	0.547
MOD_CK2_1	307	313	PF00069	0.665
MOD_CK2_1	317	323	PF00069	0.396
MOD_CK2_1	630	636	PF00069	0.215
MOD_CK2_1	66	72	PF00069	0.597
MOD_CK2_1	765	771	PF00069	0.460
MOD_CK2_1	880	886	PF00069	0.658
MOD_CK2_1	924	930	PF00069	0.694
MOD_GlcNHglycan	10	13	PF01048	0.773
MOD_GlcNHglycan	1068	1071	PF01048	0.478
MOD_GlcNHglycan	1092	1095	PF01048	0.524
MOD_GlcNHglycan	140	143	PF01048	0.630
MOD_GlcNHglycan	147	150	PF01048	0.719
MOD_GlcNHglycan	203	206	PF01048	0.636
MOD_GlcNHglycan	229	232	PF01048	0.702
MOD_GlcNHglycan	309	312	PF01048	0.598
MOD_GlcNHglycan	378	381	PF01048	0.754
MOD_GlcNHglycan	382	385	PF01048	0.488
MOD_GlcNHglycan	40	43	PF01048	0.287
MOD_GlcNHglycan	48	51	PF01048	0.554
MOD_GlcNHglycan	514	517	PF01048	0.205
MOD_GlcNHglycan	549	552	PF01048	0.424
MOD_GlcNHglycan	656	659	PF01048	0.406
MOD_GlcNHglycan	704	707	PF01048	0.517
MOD_GlcNHglycan	714	717	PF01048	0.520
MOD_GlcNHglycan	767	770	PF01048	0.476
MOD_GlcNHglycan	773	776	PF01048	0.510
MOD_GlcNHglycan	782	785	PF01048	0.520
MOD_GlcNHglycan	822	825	PF01048	0.742
MOD_GlcNHglycan	846	849	PF01048	0.416
MOD_GlcNHglycan	85	88	PF01048	0.653
MOD_GlcNHglycan	895	899	PF01048	0.669
MOD_GlcNHglycan	951	954	PF01048	0.778
MOD_GlcNHglycan	980	983	PF01048	0.637
MOD_GlcNHglycan	998	1001	PF01048	0.450
MOD_GSK3_1	1	8	PF00069	0.338
MOD_GSK3_1	1048	1055	PF00069	0.657
MOD_GSK3_1	1066	1073	PF00069	0.607
MOD_GSK3_1	108	115	PF00069	0.669
MOD_GSK3_1	1088	1095	PF00069	0.604
MOD_GSK3_1	138	145	PF00069	0.636
MOD_GSK3_1	159	166	PF00069	0.593
MOD_GSK3_1	216	223	PF00069	0.649
MOD_GSK3_1	247	254	PF00069	0.712
MOD_GSK3_1	301	308	PF00069	0.642
MOD_GSK3_1	318	325	PF00069	0.596
MOD_GSK3_1	372	379	PF00069	0.569
MOD_GSK3_1	41	48	PF00069	0.557
MOD_GSK3_1	512	519	PF00069	0.249
MOD_GSK3_1	68	75	PF00069	0.704
MOD_GSK3_1	754	761	PF00069	0.427
MOD_GSK3_1	776	783	PF00069	0.579
MOD_GSK3_1	79	86	PF00069	0.581
MOD_GSK3_1	885	892	PF00069	0.679
MOD_GSK3_1	945	952	PF00069	0.688
MOD_GSK3_1	973	980	PF00069	0.545
MOD_N-GLC_1	152	157	PF02516	0.567
MOD_N-GLC_1	216	221	PF02516	0.506
MOD_N-GLC_1	235	240	PF02516	0.540
MOD_N-GLC_1	247	252	PF02516	0.538
MOD_N-GLC_1	924	929	PF02516	0.771
MOD_N-GLC_1	948	953	PF02516	0.622
MOD_NEK2_1	1002	1007	PF00069	0.587
MOD_NEK2_1	1020	1025	PF00069	0.302
MOD_NEK2_1	1088	1093	PF00069	0.405
MOD_NEK2_1	182	187	PF00069	0.628
MOD_NEK2_1	209	214	PF00069	0.600
MOD_NEK2_1	235	240	PF00069	0.561
MOD_NEK2_1	247	252	PF00069	0.670
MOD_NEK2_1	288	293	PF00069	0.619
MOD_NEK2_1	3	8	PF00069	0.299
MOD_NEK2_1	38	43	PF00069	0.367
MOD_NEK2_1	418	423	PF00069	0.406
MOD_NEK2_1	672	677	PF00069	0.413
MOD_NEK2_1	688	693	PF00069	0.657
MOD_NEK2_1	819	824	PF00069	0.457
MOD_NEK2_1	83	88	PF00069	0.672
MOD_NEK2_1	889	894	PF00069	0.608
MOD_NEK2_1	977	982	PF00069	0.565
MOD_NEK2_2	589	594	PF00069	0.403
MOD_NEK2_2	743	748	PF00069	0.502
MOD_NEK2_2	79	84	PF00069	0.690
MOD_OFUCOSY	793	798	PF10250	0.453
MOD_PIKK_1	196	202	PF00454	0.527
MOD_PIKK_1	21	27	PF00454	0.579
MOD_PIKK_1	258	264	PF00454	0.516
MOD_PIKK_1	450	456	PF00454	0.369
MOD_PIKK_1	688	694	PF00454	0.385
MOD_PIKK_1	812	818	PF00454	0.523
MOD_PIKK_1	899	905	PF00454	0.731
MOD_PIKK_1	959	965	PF00454	0.564
MOD_PKA_1	1021	1027	PF00069	0.458
MOD_PKA_1	170	176	PF00069	0.535
MOD_PKA_1	45	51	PF00069	0.554
MOD_PKA_1	580	586	PF00069	0.205
MOD_PKA_2	1020	1026	PF00069	0.448
MOD_PKA_2	170	176	PF00069	0.535
MOD_PKA_2	272	278	PF00069	0.697
MOD_PKA_2	305	311	PF00069	0.468
MOD_PKA_2	45	51	PF00069	0.571
MOD_PKA_2	534	540	PF00069	0.358
MOD_PKA_2	580	586	PF00069	0.342
MOD_PKA_2	688	694	PF00069	0.471
MOD_PKA_2	780	786	PF00069	0.447
MOD_PKA_2	977	983	PF00069	0.572
MOD_PKA_2	991	997	PF00069	0.396
MOD_PKB_1	1019	1027	PF00069	0.492
MOD_Plk_1	182	188	PF00069	0.624
MOD_Plk_1	235	241	PF00069	0.540
MOD_Plk_1	304	310	PF00069	0.471
MOD_Plk_1	322	328	PF00069	0.448
MOD_Plk_1	660	666	PF00069	0.287
MOD_Plk_1	885	891	PF00069	0.560
MOD_Plk_2-3	72	78	PF00069	0.475
MOD_Plk_4	1028	1034	PF00069	0.516
MOD_Plk_4	114	120	PF00069	0.622
MOD_Plk_4	272	278	PF00069	0.630
MOD_Plk_4	31	37	PF00069	0.265
MOD_Plk_4	534	540	PF00069	0.344
MOD_Plk_4	672	678	PF00069	0.491
MOD_Plk_4	758	764	PF00069	0.405
MOD_Plk_4	95	101	PF00069	0.764
MOD_ProDKin_1	1052	1058	PF00069	0.672
MOD_ProDKin_1	125	131	PF00069	0.576
MOD_ProDKin_1	136	142	PF00069	0.607
MOD_ProDKin_1	153	159	PF00069	0.588
MOD_ProDKin_1	754	760	PF00069	0.502
MOD_ProDKin_1	939	945	PF00069	0.719
MOD_ProDKin_1	954	960	PF00069	0.777
MOD_ProDKin_1	970	976	PF00069	0.493
MOD_SUMO_for_1	432	435	PF00179	0.403
MOD_SUMO_rev_2	307	317	PF00179	0.451
MOD_SUMO_rev_2	902	910	PF00179	0.541
TRG_DiLeu_BaEn_1	349	354	PF01217	0.605
TRG_DiLeu_BaEn_1	534	539	PF01217	0.368
TRG_DiLeu_BaEn_3	1098	1104	PF01217	0.466
TRG_DiLeu_BaEn_3	322	328	PF01217	0.437
TRG_DiLeu_BaLyEn_6	25	30	PF01217	0.205
TRG_DiLeu_BaLyEn_6	61	66	PF01217	0.693
TRG_DiLeu_BaLyEn_6	643	648	PF01217	0.406
TRG_ENDOCYTIC_2	285	288	PF00928	0.679
TRG_ENDOCYTIC_2	387	390	PF00928	0.403
TRG_ENDOCYTIC_2	445	448	PF00928	0.381
TRG_ENDOCYTIC_2	708	711	PF00928	0.396
TRG_ER_diArg_1	1007	1010	PF00400	0.494
TRG_ER_diArg_1	1018	1021	PF00400	0.506
TRG_ER_diArg_1	1100	1103	PF00400	0.561
TRG_ER_diArg_1	18	20	PF00400	0.760
TRG_ER_diArg_1	333	335	PF00400	0.533
TRG_ER_diArg_1	45	47	PF00400	0.605
TRG_ER_diArg_1	511	513	PF00400	0.368
TRG_ER_diArg_1	580	582	PF00400	0.274
TRG_ER_diArg_1	596	598	PF00400	0.393
TRG_ER_diArg_1	686	689	PF00400	0.435
TRG_ER_diArg_1	747	750	PF00400	0.523
TRG_Pf-PMV_PEXEL_1	605	609	PF00026	0.368
TRG_Pf-PMV_PEXEL_1	646	650	PF00026	0.422
TRG_Pf-PMV_PEXEL_1	662	667	PF00026	0.255

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5L8	Leptomonas seymouri	49%	100%
A0A0S4IUZ2	Bodo saltans	30%	100%
A0A1X0P2S1	Trypanosomatidae	29%	100%
A0A3S5H4W3	Leishmania donovani	69%	100%
A4HRI7	Leishmania infantum	69%	100%
C9ZXL9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	100%
E9AC55	Leishmania major	69%	100%
E9AJF1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	68%	100%